FASCIOLA HEPATICA
FASCIOLA hepatica
Disease:Fascioliasis & liver rot in animals.
Distribution:- Common in cattle & sheep raising
countries.
FASCIOLA hepatica
Definitive host : man
Reservoir host: Cattle, sheep ,goats, buffaloes
Habitat: Bile ducts.
Intermediate host: Lymnaea snails.
Infective stage : Encysted metacercaria.
Mode of infection
Ingestion of raw vegitation or water containing encysted metacercaria.
Life cycle:
Adult FASCIOLA Hepatica
Egg:
•Size : 140 X 70 µm.
•Shape: Oval, Thin walled with
operculum.
• Color : Yellowish brown (bile stained).
•Contents : Ovum & yolk cells
(immature).
Miracidium
•Pyriform.
•Ciliated.
Lymnaea snails
Cercaria (Leptocercus)Last larval stage inside the
snail.
No sexual organs.
Cystogenous glands (help in passing out of snail & in encysting on vegetations or water).
Tail: simple & helps in leaving the snail.
Encysted MetacercariaWithout tail.
Surrounded by a
cyst
wall.
Clinical Picture :Fever. Pain & tenderness in right hypochondrium.Biliary colics.Hepatomegaly,Jaundice.Vomiting & diarrhoea. Toxaemia.Anaemia & eosinophilia.
Diagnosis
I. Clinically : A highly suggestive tetrad of:
Fever. Hepatomegaly. Pain & tenderness in the right
hypochondrium. Eosinophilia.
Diagnosis
II- Laboratory : a. Direct methods 1. Stool examination by direct smear &
concentration methods to find the characteristic eggs.
2. Bile aspiration from the duodenum & examine for eggs.
3. US.4. Computerized tomography (C.T).
Diagnosis
Diagnosis
b. Indirect Methods
ELISA, IHA ,CIEP Eosinophilia.
Thank You
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