Exercise as a Treatment for Weight Loss and Well-BeingDavid Baron, DO
Physiologic effects of exercise well documented– Runner high(opioid)– Increased self-esteem– Caloric control improved– Effective treatment for Depression
Substantial evidence, retrospective, prospective, animal & human,
Exercise has a neuroprotective effect (Kramer,Erickson, Colcombe)
Delay the onset of cognitive decline, Alzheimer’s Proliferation of active capillary beds New dendritic connections Neuronal growth in hippocampus
Data demonstrated exercise several/week(Institute Brain Aging UCI)– Reduces rate of cognitive decline with age– Increases BDNF– Decreases B-amyloid
Gunstad J. in press Comprehensive Psychiatry– 408 subjects– 20-82 yo– Body mass index inversely related to
performance all cognitive tests Regular exercise improved cognitive
performance Overall sense of well-being
Diet and exercise represent the mainstays of obesity treatment. No systematic review has been conducted comparing the effect of dietary and exercise intervention in reducing metabolic risks in overweight children.
To compare the effects of diet-only intervention with those of diet plus exercise or exercise only on weight loss and metabolic risk reduction in overweight children.
Date of download: 3/4/2014Copyright © 2014 American Medical
Association. All rights reserved.
From: Impact of Dietary and Exercise Interventions on Weight Change and Metabolic Outcomes in Obese Children and Adolescents: A Systematic Review and Meta-analysis of Randomized TrialsJAMA Pediatr. 2013;167(8):759-768. doi:10.1001/jamapediatrics.2013.1453
Flowchart for Identification of Trials for Inclusion in the Systematic Review and Meta-analyses
Obesity in children and adolescents is a major public health problem, with high or increasing prevalence reported in many countries
Diet and exercise represent the mainstays of obesity treatment
unclear whether diet plus exercise or exercise only is more effective than a diet-only intervention for improving weight status in overweight and obese children and adolescents
Fifteen studies were identified 1975-2010 Both diet-only and diet plus exercise
interventions resulted in weight loss and metabolic profile improvement.
Addition of exercise to dietary intervention led to greater improvements in – HDL– Fasting glucose, fasting insulin– triglycerides – Improved sense of well-being
Dietary interventions in conjunction with exercise interventions are effective in reducing metabolic risks, particularly HDL-C and fasting insulin levels, in overweight and obese children
How much is enough(exercise and weight loss) Must be enjoyable
– Reward– Negative reinforcement– Punishment
Aerobic vs anaerobic Effect throughout life-cycle (peds-gero)
– Gonadal steroid modulation Fad diets vs sound nutritional intake
– Many claims, limited data Supplements, herbs etc
All things in moderation
05/02/23 RiverMend Health, LLC 10
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