Download - Enlightenment 2.0 - Joseph P. Jackson III - H+ Summit @ Harvard

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Page 1: Enlightenment 2.0 - Joseph P. Jackson III - H+ Summit @ Harvard

Biomedical Innovation today

Biotech 2.0

Page 2: Enlightenment 2.0 - Joseph P. Jackson III - H+ Summit @ Harvard

A Tale of 2 Technologies, Computing Vs Biology

The Futurist's Bias: Accidents of History, Economics, CultureSTEMI (J Smart) compression not inevitable.

Transistor, anti-trust forced to be licensed broadly, Shockley alienated co-workers, ARPA Net, open standards = Web explosion

No Guarantee we're going to make it for biomedicine!Optimism, G Church Like the 50s for sny bio parts (transistors+capacitors) Even with Electronics because we can use CAD. Unique advantage of directed evolution, trillions of combinations to throw at problem. Hard take off, sequenced/synthesis... will it be enough?

Page 3: Enlightenment 2.0 - Joseph P. Jackson III - H+ Summit @ Harvard

Show me the Money ?$$

Show me the Innovation!

Cure Entrepreneurs! Biotech has destroyed more capital than any sector in history (-90 biliion until 2008 when it finally showed a profit). PHARMA doesn't create improved health outcomes.

Myth of Patents: Penicillin, Polio Vaccine, Defeat of Smallpox Recombinant DNA

Salk: Can we Patent the Sun? (Polio Vaccine)Are we being good ancestors? NO!

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Open Science/Biology/Innovation Paradigm IS

1) Collective Intelligence: semantic web for biology, BioTorrents, massive open data sets, OA Publishing, Slashdot for Science Karma systems to supplant static peereview, Mendley (Last FM for research papers) Don't wait for AI, build Epistemology 2.0 NOW

2) Interoperable technology stacks: Stem Cells, Gene therapy vectors, BiobricksBiology fundamentally distributed, cheap (sunlight + sugar), self replicating, cell cultures--share and share alike Biobanking for these components should be DEFAULT. No one click shopping? 3) Radically better business models, financing mechanisms/prizes/instruments, incentivize sharing, require it, demand to get what your taxes pay for. Monopolies are Obsolete, Progress/Evolution depends on Copying...whether in Biology or Culture. Perversity of Patent as "incentive" for progress. Greenxchange, Innocentive, etc

Page 5: Enlightenment 2.0 - Joseph P. Jackson III - H+ Summit @ Harvard
Page 6: Enlightenment 2.0 - Joseph P. Jackson III - H+ Summit @ Harvard

Modern University... Obsolete? Open Courseware, Fab Lab Network Schizophrenic, Public vs Private? Harvard Horror Story

Page 7: Enlightenment 2.0 - Joseph P. Jackson III - H+ Summit @ Harvard

How to Blow a Billion

40 Billion $ endowment 8 billion evaporated over night. Tech TransferWhere Innovation goes to Die. Wanna bet your future on them?

Page 8: Enlightenment 2.0 - Joseph P. Jackson III - H+ Summit @ Harvard

Desperate Times = Garage Biotech

Page 9: Enlightenment 2.0 - Joseph P. Jackson III - H+ Summit @ Harvard

Tired of Doing it all Yourself DIY?

Come Do it With US

Community Lab Hackerspace for Citizen Science

Page 10: Enlightenment 2.0 - Joseph P. Jackson III - H+ Summit @ Harvard

She's BioCurious!

Page 11: Enlightenment 2.0 - Joseph P. Jackson III - H+ Summit @ Harvard

Straining Towards the Singularity

Innovation Constipation20 yr patent monopoliesSingularity is not NEAR!

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P2P Shall set us Free DIY or DIEopensciencesummit.com