Prepared by: Joevi Jhun A. Idul BSE- BioSci 3
Botulism
Botulism(food poisoning)
DiseaseCause
Signs and SymptomsIncubation Period
TreatmentPrevention
DiseaseBotulism is a rare but serious illness caused by Clostridium botulinum bacteria. The bacteria may enter the body through wounds, or by eating them from improperly canned or preserved food.
Foodborne botulismcaused by eating foods that contain botulism toxin
Intestinal botulism (infant and child/adult)caused by ingesting spores of the bacteria which germinate and produce toxin in the intestine
Wound botulism C. botulinum spores germinate in the wound
Inhalation botulism
Aerosolized toxin is inhaleddoes not occur naturally and may be indicative of bioterrorism
Botulism(food poisoning)
DiseaseCause
Signs and SymptomsIncubation Period
TreatmentPrevention
CauseClostridium botulinum is found in soil and untreated
water throughout the world.
Clostridium botulinum is a Gram-positive, rod-shaped, anaerobic, spore-forming, motile bacterium with the
ability to produce the neurotoxin botulinium.
Clostridium botulinum
Clostridium botulinum
• COLONIZATION OF THE GUTThe most common form in Western countries is infant botulism. This occurs in infants who are colonized with the bacterium in the small intestine during the early stages of their lives.
The bacterium then produces the toxin, which is absorbed into the bloodstream. The consumption of honey during the first year of life has been identified as a risk factor for infant botulism.
• FOOD
Toxin that is produced by the bacterium within containers of food that have been improperly preserved is the most common cause of food-borne botulism.
• WOUNDWound botulism results from the contamination of a wound with the bacteria, which then secrete the toxin into the bloodstream.
• INHALATIONIsolated cases of botulism have been described after inhalation by laboratory workers.
• INJECTIONBotulism has occurred after cosmetic use of inappropriate strengths of Botox.
Botulism(food poisoning)
DiseaseCause
Signs and SymptomsIncubation Period
TreatmentPrevention
Signs and SymptomsIn adults, symptoms may include:
• Abdominal cramps• Breathing difficulty that
may lead to respiratory failure
• Difficulty swallowing and speaking
• Double vision• Nausea• Vomiting• Weakness with paralysis
(equal on both sides of the body)
Signs and Symptoms
Symptoms in infants may include:
• Constipation• Drooling• Poor feeding and weak
sucking• Respiratory distress• Weak cry• Weakness, loss of muscle
tone
Botulism(food poisoning)
DiseaseCause
Signs and SymptomsIncubation Period
TreatmentPrevention
Incubation Period
Infants: 3-30 daysChildren and adults: 12-72 hours
Botulism(food poisoning)
DiseaseCause
Signs and SymptomsIncubation Period
TreatmentPrevention
TreatmentYou will need medicine to fight the toxin produced by the bacteria, called botulinus antitoxin.
You will have to stay in the hospital if you have breathing trouble. A tube may be inserted through the nose or mouth into the windpipe to provide an airway for oxygen. You may need a breathing machine.
Patients who have trouble swallowing may be given fluids through a vein (by IV). A feeding tube may be inserted.
Health care providers must tell state health authorities or the U.S. Centers for Disease Control and Prevention about patients with botulism, so that the contaminated food can be removed from stores.
Some people are given antibiotics, but they may not always help.
Botulism(food poisoning)
DiseaseCause
Signs and SymptomsIncubation Period
TreatmentPrevention
PreventionNEVER give honey or corn syrup to infants younger than 1 year old -- not even just a little taste on a pacifier.
Prevent infant botulism by breastfeeding only, if possible.
Always throw away bulging cans or foul-smelling preserved foods. Sterilizing home-canned foods by pressure cooking them at 250 degrees Fahrenheit for 30 minutes may reduce the risk for botulism.
Keep foil-wrapped baked potatoes hot or in the refrigerator, not at room temperature.
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