1999 pyridine derivatives

pyridine derivativesR 0380

33 - 157Synthesis of Chiral 1,4-Dihydropyridines by Diastereoface-SelectiveAsymmetric Addition to Nicotinic Amides. — The pyridinium saltsderived from compounds (I) and (V) undergo diastereoface-selective additionreactions with organometallic reagents yield chiral 1,4-dihydropyridines (IV)and (VIII). — (YAMADA, SHINJI; ICHIKAWA, MAYUMI; Tetrahedron Lett.40 (1999) 22, 4231-4234; Dep. Chem., Fac. Sci., Ochanomizu Univ., Bunkyo,Tokyo 112, Japan; EN)

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