ZyCoV-D THE Egypt Cadilla healthcare + Dr. Reddy’s Lab · 2021. 1. 4. · Dr. Reddy’s Lab +...
Transcript of ZyCoV-D THE Egypt Cadilla healthcare + Dr. Reddy’s Lab · 2021. 1. 4. · Dr. Reddy’s Lab +...
THE RICH AXISFor universal immunisation, the world would need 2 doses of vaccines for 7.8 billion people. But the rich countries have already ordered a bulk of the vaccines to be manufactured in 2021
Seven vaccines are in various stages of clinical trials on humans in India. The vaccine industry is working on both international and domestic vaccine candidates
Cambridge. UKCambridge. UKAstrazeneca/Oxford Astrazeneca/Oxford
CanadaCanada
MexicoMexico
BrazilBrazil
Latin America Latin America Bloc**Bloc**
EgyptEgypt
EU*EU*
UzbekistanUzbekistan
IndiaIndia
NepalNepal
ChinaChina
IndonesiaIndonesia
AustraliaAustralia
JapanJapanS KoreaS Korea
Maryland, USAMaryland, USANovavaxNovavax
New York, USANew York, USAPfizer/ BioNTechPfizer/ BioNTech
Massachucetts, USMassachucetts, USModernaModerna
Moscow, RussiaMoscow, RussiaGamaleyaGamaleya
Paris, FranceParis, FranceSanofi/GSKSanofi/GSK
Countries with ongoing phase 3 clinical trials
Top 6 vaccine manufacturers and destination of their product
7.8 billiontotal people to be vaccinated
4.7 billionPeople to be vaccinated for herd immunity***
2.2 billionAdults at severe risk of infection
2.3 millionTotal vaccine doses administered****
3.7 billionPeople are willing to take the vaccine
2 billiondoses COVAX will be provided in 2021
162vaccine candidates in pre-clinical trials
52 vaccine candidates in clinical trials
13 vaccine candidates in phase 3
Advance market commitments (as of December 18, 2020 data)• Total worldwide confirmed purchases of covid-19 vaccines: 7.7 billion doses • Total confirmed doses purchased by high-income countries: 4 billion• Total confirmed doses purchased by upper-middle-income countries 1.1 billion• Total confirmed doses purchased by lower-middle-income countries: 1.8 billion• Purchases by low-income countries: 0 • Total purchased by covax: 870 million
Top 5 hoarders of COVID 19 vaccines
USACOVAX
EUIndia
UK
Explanation: *EU: 27 countries of the European Union; **Latin America bloc: all countries in the region, except Brazil;***at least 60% population needs to be vaccinated for herd immunity. The companies are providing to their home countries too. ****as of December 22, 2020; Covax is a global body which would supply to most countries in the world
Source: London School of Hygiene & Tropical Medicine Vaccine Centre, Duke Global Health Innovation Center, www.bloomberg.com, www.ourworldindata.org, www.who.int; www.pib.nic.in; https://www.bmj.com/content/371/bmj.m4704
THE INDIAN VACCINE BAZAAR
Covishield (chimpanzee adenovirus platform) SII + AstraZeneca Phase 2/3
Applied for EUA
Covaxin (inactivated virus) Bharat biotech + ICMR Phase 3
Applied for EUA
ZyCoV-D (DNA vaccine) Cadilla healthcare + dept of biotechnology Phase 2
Sputnik V (human adenovirus vaccine) Dr. Reddy’s Lab + Gamaleya National Centre phase 3 about to begin
NVX-CoV2373 (protein subunit) SII + Novavax phase 3 under consideration
COVID-19 vaccine (recombinant protein antigen based vaccine) Biological E Phase 1 and 2
HGCO 19 (mRNA based vaccine) Gennova + HDT USA phase 1 and 2 human trials approved
0M 200M 400M 600M 800M 1000M 1200M 1400M 1600M 1800M 2000M 2200M 2400M 2600M
Potential dose purchases Confirmed dose purchases
COVER STORY/VACCINE
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