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WORLD CONFERENCEON LUTEINIZING HORMONE IN ARTSECOND EDITION:

6 - 7 November 2020 Athens, Greece

A NEW GALAXY IS BORN

InternationalConference

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OverviewThe role of luteinizing hormone (LH) during folliculogenesis has intrigued the scientific and medical community for at least three decades. There is an emerging galaxy of research to explore concerning this enigmatic subject.

The availability of recombinant drugs now offers, for the first time, the opportunity to examine the role of follicle stimulating hormone and LH separately. An emerging topic during last year’s conference was LH supplementation to improve the outcome in a subgroup of low prognosis patients selected according to POSEIDON classification. During this conference we will discuss the management of these low prognosis patients in greater detail. Notably, we will move beyond controlled ovarian stimulation to explore further the involvement of LH in personalizing the luteal phase and in male infertility. Also, on the agenda will be the extra-gonadal effect of LH, including potential immune-modulation at the endometrium. Following the precedent set at last year’s conference, considerable time will be devoted to basic science, alongside such controversial issues as progesterone rise and pharmacogenomics. This year we have attracted prominent scientists from the worlds of endocrinology, andrology, immunology and embryology to take part in our engaging exploration of the LH galaxy.

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Conference attendees will leave with the ability to;

• Understand the importance of luteinizing activity during folliculogenesis and beyond.

• Understand the dynamics of hypothalamic-pituitary axis in the pathogenesis of hypo- and normo-gonadotropic amenorrhea.

• Comprehend the concept of relative gonadotropin deficiency.

• Discuss and debate the management of low prognosis patients.

• Comprehend the clinical utility of the POSEIDON classification for the management of low prognosis women.

• Discover the clinical relevance of LH supplementation in ART.

• Appreciate the clinical relevance and pathogenesis of the progesterone rise during COS.

• Analyse the relevance of LH during the luteal phase and Introduce the concept of individualized luteal phase support.

• Explore the potential of LH in male infertility.

Learning Objectives

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This programme is designed for clinicians and biologists working in assisted reproductive medicine, who want to acquire up-to date information to improve their current practice.

This programme will be submitted for CME accreditation to EACCME® (European Accreditation Council for Continuing for Medical Education).

Target Audience

Accreditation

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Faculty

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Chairs Carlo Alviggi Federico II University of NaplesNaples, Italy

Sandro C. EstevesANDROFERT - Andrology & Human Reproduction ClinicCampinas, Brazil

Robert FischerFertility Centre HamburgHamburg, Germany

Peter HumaidanFertility Clinic, Skive Regional HospitalFaculty of Health, Aarhus UniversityAarhus, Denmark

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FacultyCarlo Alviggi Federico II University of NaplesNaples, Italy

Sandro C. EstevesANDROFERT - Andrology & Human Reproduction ClinicCampinas, Brazil

Robert FischerFertility Centre HamburgHamburg, Germany

Jean-Noël HuguesUniversity Paris XIIIParis, France

Peter HumaidanFertility Clinic, Skive Regional HospitalFaculty of Health, Aarhus UniversityAarhus, Denmark

Philippe LehertFaculty of EconomicsAcademy of LouvainLouvain, Belgium

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Antonis MakrigiannakisLaboratory of Human ReproductionMedical School, University of CreteHeraklion, Greece

Nick Raine-FenningNurture Fertility, School of MedicineUniversity of NottinghamNottingham, UK

Daniele SantiUniversity of Modena and Reggio EmiliaModena, Italy

Manuela SimoniUniversity of Modena and Reggio EmiliaModena, Italy

Marc-André SirardCentre de Recherche en Biologie de la ReproductionLaval UniversityQuébec, Canada

Sesh K. SunkaraKing’s College LondonLondon, UK

Filippo Maria UbaldiG.E.N.E.R.A. Centre for Reproductive MedicineRome, Italy

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Scientific Programme

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Scientific Programme

Friday, 6 November 2020

Session I

Moving away from earth:lessons from gonadotropins system

Chairs: Carlo Alviggi, Italy - Robert Fischer, Germany

08.00

08.30

08.35

08.40

08.45

09.10

09.20

09.45

L1

L2

Registration

MedEA WelcomeRobert Fischer, Germany

Local welcomeTo be announced Welcome and introductionCarlo Alviggi, Italy

Gonadotropins during the ovarian cycles:the galaxy we knowMarc-André Sirard, Canada

QuestionsMarc-André Sirard, Canada

Hypothalamic amenorrhea and PCOS:two sides of the moonAntonis Makrigiannakis, Greece

QuestionsAntonis Makrigiannakis, Greece

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09.55

10.15

10.40

10.50

11.15

11.25

12.30

13.30

13.55

L3

L4

L5

Coffee break

The role of LH in male infertility: an altered connection between space and earth Manuela Simoni, Italy

QuestionsManuela Simoni, Italy

Isoforms and polymorphisms of gonadotropins and their receptors in human reproduction:a partial eclipse Daniele Santi, Italy

QuestionsDaniele Santi, Italy

Panel discussion

Lunch

The periodic comet of POR:the novel POSEIDON classificationSandro C. Esteves, Brazil

QuestionsSandro C. Esteves, Brazil

Session II

Flying through the stars: how to maximize success in controlled ovarian stimulation

Chairs: Robert Fischer, GermanyAntonis Makrigiannakis, Greece

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14.05

14.30

14.40

15.00

15.25

15.35

16.00

16.10

17.00

L6

L7

L8

Orbiting around clinical practice:management of the four POSEIDON groupsCarlo Alviggi, Italy

QuestionsCarlo Alviggi, Italy Coffee break

Progesterone rise: the black hole of controlled ovarian stimulationJean-Noël Hugues, France

QuestionsJean-Noël Hugues, France

Ongoing pregnancy rate as a valid endpoint: mapping a new star systemSesh Sunkara, UK

QuestionsSesh Sunkara, UK

Panel discussion

End of first day

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Session III

A new universe to explore: medical trends in ART

Saturday, 7 November 2020

09.00

09.25

09.35

10.00

10.10

10.30

10.55

L9

L10

L11

Antral follicle count: an “objective” dimension?Nick Raine-Fenning, UK

QuestionsNick Raine-Fenning, UK

Follicular waves during the natural cycle:use of Duo-Stim in POSEIDON groupsFilippo M. Ubaldi, Italy

QuestionsFilippo M. Ubaldi, Italy

Coffee break

Ovulation triggering: the big bang of an adequate luteal phasePeter Humaidan, Denmark

QuestionsPeter Humaidan, Denmark

Chairs: Robert Fischer, GermanySandro C. Esteves, Brazil

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11.05

11.30

11.40

12.40

12.45

L12 Landing in Real World “Data”Philippe Lehert, Belgium

QuestionsPhilippe Lehert, Belgium

Panel discussion

Concluding remarks Peter Humaidan, Denmark

End of the conference and closing lunch

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General Information

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Venue

Language

CME Provider

This live educational conference will take place at: Grand Hyatt Athens115, Syngrou AvenueAthens, 117 45

www.hyatt.com/en-US/hotel/greece/grand-hyatt-athens/athgh

The official language of this live educational conference will be English.

Med.E.A – Medical Education AcademyChloe Xilinas: Programme and Relations Manager in Medical Educationchloe.xilinas@medea.academy

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RegistrationFor registration, dinner, accommodation and any logistic inquiry, please contact:

EVENT PLANET SRLathens2020@eventplanetgroup.comPhone: +39 (0)81 552 9399

Registration fee

225.00€

The registration includes:• Scientific sessions• Coffee breaks and lunch• Educational materials• Certificate of attendanceDinner is not included

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Funding

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Med.E.A Srl educational programmes are organized solely to promote the exchange and dissemination of scientific and medical information. No forms of promotional activities are permitted. There may be presentations discussing investigational uses of various products.

These views are the responsibility of the named speakers, and do not represent an endorsement or recommendation on the part of Med.E.A. Srl. This independent programme is made possible thanks to an educational grant received from Merck KGaA.

www.medea.academy

Copyright © MedEA, 2020. All rigths reserved

Med.E.A. Medical Education AcademyVia Turati n 40 / 20121 Milan, Italy