Workshop No. 237 FLUIDIZED BED AS MULTIPURPOSE...
Transcript of Workshop No. 237 FLUIDIZED BED AS MULTIPURPOSE...
WHY PARTICIPATING?
This workshop on fluidized bed technology is a perfect combination of theory, hands-on training and demonstrations.
The workshop provides the basics of drying, granulating, coating and pelletizing and outlines their applications in the powder processing industry.
This workshop is the perfect investment for those who wish to acquire knowledge of fluidized bed technology.
WHO SHOULD PARTICIPATE?
Typically, operators and researchers from the pharmaceutical and related industries will get the most out of this workshop.
However, the workshop is also perfectly suitable for those who want a detailed overview of fluidized bed technology in a short space of time.
PROGRAM
TUESDAY, 23 JANUARY 201812:00 Transfer from hotel to TTC
12:15 Reception and registration, snack bu�et
12:50 Introduction. Andreas Gottschalk
13:00 Basic principles of �uidized bed processing Focussing on the advantages and disadvantages of �uidization. Also covering characteristics of the �uidized bed, mixing, and segregation during the �uidization process. Agba Salman
13:45 Fluidized bed processing: the �uidized bed drying process. Outlining the fundamentals of the �uidized bed drying process with special emphasis on the heat transfer process. Also discussing the in�uence of various process variables on the drying time and �uidized bed temperature. Agba Salman
14:30 Co�ee break
15:00 Fluidized bed processing: the �uidized bed granulation process. Identifying how process parameters impact on the granulation process in �uidized bed granulation. Various results from literature are compared and discussed. Agba Salman
16:00 Scale-up of �uid bed processes. Introduction to scienti�cally and empirically based approaches, allowing for successful scale-up from lab to production volumes. Annette Grave
16:45 PAT case study 1: Inline moisture measurement by microwave technology. Carmen Diáz
17:30 Transfer to hotel
19:30 Workshop dinner
WEDNESDAY, 24 JANUARY 201808:40 Transfer from hotel to TTC
09:00 Spray systems for �uidized bed applications. Looking closer at the most relevant spray technologies for pharmaceutical applications. Discussing the impact of an adequate spray system function on product and process quality. Norbert Pöllinger
09:45 Continuous �uidized bed processing. Comparing batch and continuous operations and describing their various process options. Giving an overview on state-of-the-art equipment for continuous �uidized bed processing. Michael Jacob
10:30 Hands-on demonstration - a close look at traditional and innovative �uidized bed processes (GMP/non-GMP) – MicroPx Technology- how to produce high drug loaded micropellets. Michael Jacob
11:00 Co�ee break
11:30 Process optimization considering QbD and using DoE - the basis for successful scale-up. Process optimization is a pre-requisite for successful scale-up and process validation. Presenting real-life examples of how to apply Quality by Design and Design of Experiments. Guido Büch
12:30 Lunch
13:30 PAT case study 2: Inline particle size monitoring by spatial �lter technology (SFT). Stefan Dietrich
14:15 From lab to production scale - a look at equipment for the real world. Discovering the full range of state-of-the-art �uidized beds units from grams to tons. Sales Team
14:45 Co�ee break / Transfer to Innovation Center
15:20 Hands-on demonstration - a close look at traditional and innovative �uidized bed processes.– CPS Technology - the new �uidized bed rotor process for direct pelletisation – Fluidized bed granulation - applying a new tangential spraying technology – Wurster �uidized bed pellet coating - modern applications with an established technology– MODCOS wet granulation/drying A modular contiuous processing solution– MODCOS direct compaction - from powder to tablet
Lilia Sprich & Team Innovation Center
17:00 Transfer to hotel
19:00 Workshop dinner
THURSDAY, 25 JANUARY 201808:40 Check-out from hotel and transfer to TTC
09:00 Powder Layering - a real high speed processOutlining and discussing �ndings from a process to quickly gain particle mass and size. Norbert Pöllinger
09:45 Preparation of multiparticulates using �uidized bed - principles of drug layering and functional coating. Covering formulation and process variables in�uencing drug layering and coating at di�erent scales. Also addressing post coating processes (e.g. curing) and their in�uence on drug release and stability. Finally introducing an “assembly kit” for small scale development of multilayer pellets. Karl-Gerhard Wagner
10:30 Co�ee break
11:00 Excipients for �uidized bed processes. Providing an insight into the common exipients for the various �uidized bed processes such as granulation, pelletization and coating. Jörg Brunemann
11:45 Semi- and fully automatic cleaning of �uidized bed installations applying WIP and CIP. Exploring how to best use cleaning systems in the latest pharmaceutical processes - illustrated on �uidized bed systems. Axel Schi�mann
12:30 Summary and snack bu�et
13:00 Transfer to Basel, German Railway Station (Badischer Bahnhof), Swiss Railway Station (SBB) and EuroAirport
SPEAKERS
Dr. Jörg Brunemann HARKE Pharma GmbH, GermanyDr. Guido Büch Novartis AG, SwitzerlandCarmen Diáz TEWS Elektronik GmbH & Co. KG, GermanyStefan Dietrich Parsum GmbH, GermanyDr. Michael Jacob Glatt Ingenieurtechnik GmbH, GermanyDr. Norbert Pöllinger Glatt GmbH, GermanyProf. Dr. Agba Salman University of Sheffield, United KingdomDr. Axel Schiffmann F. Hoffmann-La Roche AG , SwitzerlandProf. Dr. Gerhard Wagner Universität Bonn, Germany
MODERATION
Andreas Gottschalk, Technology Training Center, Germany
DETAILS >> The participation fee is € 1.490,– (exclusive of VAT).
>> This fee includes participation, accompanying course notes, daytime catering and dinner. Any other expenses are to be borne by the attendee.
>> Free attendance granted to a limited number of students.
>> Participation is limited. Registrations will be confirmed on a first come first serve basis.
>> Courses taking place in Germany are subject to Value Added Tax (VAT).
>> Each participant will receive a certificate of attendance at the end of the course.
>> Registration deadline: 07 December 2017
REGISTRATION
Workshop:FLUIDIZED BED PROCESSING23 – 25 January 2018
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ORGANIZATON AND LOCATION
TTC - Technology Training CenterRegina Bernstein / Andreas Gottschalk / Bianca NowakWerner-Glatt-Straße 1, 79589 Binzen, GermanyTel +49 7621 - 664 308Fax +49 7621 - 664 798E-mail [email protected]
For further information or online registration please visit us on
www.ttc-binzen.de