Work Participation Outcome Measures · Brouwer et al.,: Relationships among work productivity...
Transcript of Work Participation Outcome Measures · Brouwer et al.,: Relationships among work productivity...
![Page 1: Work Participation Outcome Measures · Brouwer et al.,: Relationships among work productivity concepts and health-related quality of life ... Work performance – the ability to work](https://reader035.fdocuments.us/reader035/viewer/2022070805/5f0394257e708231d409bed6/html5/thumbnails/1.jpg)
Monique A.M. Gignac, PhD Associate Scientific Director & Senior Scientist,
Institute for Work and Health;
Senior Scientist, Toronto Western Research Institute, University Health Network;
Associate Professor, Dalla Lana School of Public Health, University of Toronto
Work Participation
Outcome Measures Initiative on Methods, Measurement and Pain Assessment in Clinical Trials (IMMPACT-
XVII), Washington, DC, April 17-18, 2014
![Page 2: Work Participation Outcome Measures · Brouwer et al.,: Relationships among work productivity concepts and health-related quality of life ... Work performance – the ability to work](https://reader035.fdocuments.us/reader035/viewer/2022070805/5f0394257e708231d409bed6/html5/thumbnails/2.jpg)
Presentation Overview
1) Types of work outcomes
2) Challenges related to work participation concepts and
their measurement
3) The complexity of the work – keeping context in mind
2 www.iwh.on.ca
![Page 3: Work Participation Outcome Measures · Brouwer et al.,: Relationships among work productivity concepts and health-related quality of life ... Work performance – the ability to work](https://reader035.fdocuments.us/reader035/viewer/2022070805/5f0394257e708231d409bed6/html5/thumbnails/3.jpg)
OMERACT Worker Productivity Working Group
Rheumatic diseases as a model for understanding work
participation:
Associated with significant amounts of pain
New treatments can be “life altering”
3 www.iwh.on.ca
![Page 4: Work Participation Outcome Measures · Brouwer et al.,: Relationships among work productivity concepts and health-related quality of life ... Work performance – the ability to work](https://reader035.fdocuments.us/reader035/viewer/2022070805/5f0394257e708231d409bed6/html5/thumbnails/4.jpg)
OMERACT Worker Productivity Working Group
Patient Research Partners:
Ailsa Bosworth, U.K.;
Catherine Hofstetter, Canada;
Amye Leong, U.S.A.;
David Magnusson, Sweden;
Albert Schiepers, Netherlands.
Industry Research Partners:
Mary Cifaldi, Abbvie, U.S.A.;
Oana Purcaru, UCB Pharma, Belgium;
Carol Gaiche, Eli Lilly, U.S.A.;
Evo Alemao, BMS, U.S.A.
Researchers:
Dorcas Beaton, Canada;
Claire Bombardier, Canada;
Annelies Boonen, Netherlands;
Anne Marie Braakman, Netherlands;
Sabrina Dadoun, France;
Reuben Escorpizo, U.S.A.,
Bruno Fautrel, France;
Monique Gignac, Canada;
Sofia Hagel, Sweden;
Diane Lacaille, Canada;
Sarah Leggett, U.K.;
Jolanda Luime, Netherlands;
Antje Neunen, Netherlands;
Ingemar Petersson, Sweden;
Carmen Stolwijk, Netherlands;
Ken Tang, Canada;
Suzanne Verstappen, U.K.
4 www.iwh.on.ca
![Page 5: Work Participation Outcome Measures · Brouwer et al.,: Relationships among work productivity concepts and health-related quality of life ... Work performance – the ability to work](https://reader035.fdocuments.us/reader035/viewer/2022070805/5f0394257e708231d409bed6/html5/thumbnails/5.jpg)
OMERACT Worker Productivity Working Group
Patient Research Partners:
Ailsa Bosworth, U.K.;
Catherine Hofstetter, Canada;
Amye Leong, U.S.A.;
David Magnusson, Sweden;
Albert Schiepers, Netherlands.
Industry Research Partners:
Mary Cifaldi, Abbvie, U.S.A.;
Oana Purcaru, UCB Pharma, Belgium;
Carol Gaiche, Eli Lilly, U.S.A.;
Evo Alemao, BMS, U.S.A.
Researchers:
Dorcas Beaton, Canada;
Claire Bombardier, Canada;
Annelies Boonen, Netherlands;
Anne Marie Braakman, Netherlands;
Sabrina Dadoun, France;
Reuben Escorpizo, U.S.A.,
Bruno Fautrel, France;
Monique Gignac, Canada;
Sofia Hagel, Sweden;
Diane Lacaille, Canada;
Sarah Leggett, U.K.;
Jolanda Luime, Netherlands;
Antje Neunen, Netherlands;
Ingemar Petersson, Sweden;
Carmen Stolwijk, Netherlands;
Ken Tang, Canada;
Suzan Verstappen, U.K.
5 www.iwh.on.ca
Dorcas Beaton
Annelies Boonen
Suzanne Verstappen
![Page 6: Work Participation Outcome Measures · Brouwer et al.,: Relationships among work productivity concepts and health-related quality of life ... Work performance – the ability to work](https://reader035.fdocuments.us/reader035/viewer/2022070805/5f0394257e708231d409bed6/html5/thumbnails/6.jpg)
Are employment outcomes of value in trials and
other interventions?
Work provides:
Financial resources
Potential access to employer benefit plans
(medication, extended health)
Psychological advantages (e.g., identity, purpose)
Social benefits
May promote physical activity
6 www.iwh.on.ca
![Page 7: Work Participation Outcome Measures · Brouwer et al.,: Relationships among work productivity concepts and health-related quality of life ... Work performance – the ability to work](https://reader035.fdocuments.us/reader035/viewer/2022070805/5f0394257e708231d409bed6/html5/thumbnails/7.jpg)
Work across the life span
Youth employment experiences linked to education
and later employment
Aging workers:
Youngest of the baby boomers are 50 years old
Mandatory retirement disappearing
Workers encouraged/need to work longer
Age associated with increased risk of various painful
health conditions
7 www.iwh.on.ca
![Page 8: Work Participation Outcome Measures · Brouwer et al.,: Relationships among work productivity concepts and health-related quality of life ... Work performance – the ability to work](https://reader035.fdocuments.us/reader035/viewer/2022070805/5f0394257e708231d409bed6/html5/thumbnails/8.jpg)
Work of interest to employers, insurers, organized labour,
health and safety associations, governments, clinicians
and others
Disability and productivity costs estimated to be 2-4 times
greater than direct health care costs (Allaire et al., 2005; Fautrel &
Guillemin, 2002; Gabriel et al., 1997; Li et al., 2006; Merkesdal et al., 2001; Wolfe et al., 2005; Yelin et al.,
2004)
8 www.iwh.on.ca
![Page 9: Work Participation Outcome Measures · Brouwer et al.,: Relationships among work productivity concepts and health-related quality of life ... Work performance – the ability to work](https://reader035.fdocuments.us/reader035/viewer/2022070805/5f0394257e708231d409bed6/html5/thumbnails/9.jpg)
Conceptual Models
WHO International Classification of Functioning,
Disability and Health (ICF) (WHO, 2001)
Brouwer et al.,: Relationships among work productivity
concepts and health-related quality of life (Brouwer, Meerding,
Lamers &Severens, 2005)
Sandqvist & Henriksson: The person-environment fit in
work participation (Sandqvist & Henriksson, 2004).
9 www.iwh.on.ca
![Page 10: Work Participation Outcome Measures · Brouwer et al.,: Relationships among work productivity concepts and health-related quality of life ... Work performance – the ability to work](https://reader035.fdocuments.us/reader035/viewer/2022070805/5f0394257e708231d409bed6/html5/thumbnails/10.jpg)
Conceptual Models
Factors contributing to work participation go beyond
pain and health-related factors
Work participation outcomes are inter-connected
10 www.iwh.on.ca
![Page 11: Work Participation Outcome Measures · Brouwer et al.,: Relationships among work productivity concepts and health-related quality of life ... Work performance – the ability to work](https://reader035.fdocuments.us/reader035/viewer/2022070805/5f0394257e708231d409bed6/html5/thumbnails/11.jpg)
Conceptual Models
Pain is complex and determined by biological,
psychological, social and environmental factors
Health→Work Work→Health
11 www.iwh.on.ca
![Page 12: Work Participation Outcome Measures · Brouwer et al.,: Relationships among work productivity concepts and health-related quality of life ... Work performance – the ability to work](https://reader035.fdocuments.us/reader035/viewer/2022070805/5f0394257e708231d409bed6/html5/thumbnails/12.jpg)
Conceptual Models
The nature of the pain experience (e.g., flares, episodic,
continuous) needs to be considered in light of work
12 www.iwh.on.ca
![Page 13: Work Participation Outcome Measures · Brouwer et al.,: Relationships among work productivity concepts and health-related quality of life ... Work performance – the ability to work](https://reader035.fdocuments.us/reader035/viewer/2022070805/5f0394257e708231d409bed6/html5/thumbnails/13.jpg)
Work Outcomes
Job status (e.g., long-term disability/work disability)
Sick leave or short-term disability
Absenteeism
13 www.iwh.on.ca
![Page 14: Work Participation Outcome Measures · Brouwer et al.,: Relationships among work productivity concepts and health-related quality of life ... Work performance – the ability to work](https://reader035.fdocuments.us/reader035/viewer/2022070805/5f0394257e708231d409bed6/html5/thumbnails/14.jpg)
Absenteeism
Prior 3 months/6 months?
Number of days versus an “episode”?
Attributed to a health condition?
The price of better health – more absenteeism?
14 www.iwh.on.ca
![Page 15: Work Participation Outcome Measures · Brouwer et al.,: Relationships among work productivity concepts and health-related quality of life ... Work performance – the ability to work](https://reader035.fdocuments.us/reader035/viewer/2022070805/5f0394257e708231d409bed6/html5/thumbnails/15.jpg)
Presenteeism: Measuring reduced work
quantity and quality
1. Is working easy or difficult (worker ability/ functioning)?
2. Are workers with painful conditions like arthritis as
productive as they could be if they had no health
problem?
15 www.iwh.on.ca
![Page 16: Work Participation Outcome Measures · Brouwer et al.,: Relationships among work productivity concepts and health-related quality of life ... Work performance – the ability to work](https://reader035.fdocuments.us/reader035/viewer/2022070805/5f0394257e708231d409bed6/html5/thumbnails/16.jpg)
Work Outcomes
Work scheduling
Job disruptions
Job stress
Changing jobs
(Gignac, Cao, Lacaille, Anis & Badley, 2008)
16 www.iwh.on.ca
![Page 17: Work Participation Outcome Measures · Brouwer et al.,: Relationships among work productivity concepts and health-related quality of life ... Work performance – the ability to work](https://reader035.fdocuments.us/reader035/viewer/2022070805/5f0394257e708231d409bed6/html5/thumbnails/17.jpg)
OMERACT Worker Productivity Working Group
(2006) Four work streams:
1. Global assessments of at-work limitations/productivity
loss
2. Multi-item approaches to measuring at-work
limitations/productivity
3. Contextual factors related to worker productivity
4. Interpretability of worker productivity outcomes (e.g.,
PAS, MID)
17 www.iwh.on.ca
![Page 18: Work Participation Outcome Measures · Brouwer et al.,: Relationships among work productivity concepts and health-related quality of life ... Work performance – the ability to work](https://reader035.fdocuments.us/reader035/viewer/2022070805/5f0394257e708231d409bed6/html5/thumbnails/18.jpg)
OMERACT Worker Productivity Working Group
(2006)
Started with 26 different instruments
Measures evaluated using the OMERACT filter:
1. Truth (face/content validity and construct validity)
2. Discrimination (reliability, responsiveness, use in RCTs,
score interpretability)
3. Feasibility (ease of application)
18 www.iwh.on.ca
![Page 19: Work Participation Outcome Measures · Brouwer et al.,: Relationships among work productivity concepts and health-related quality of life ... Work performance – the ability to work](https://reader035.fdocuments.us/reader035/viewer/2022070805/5f0394257e708231d409bed6/html5/thumbnails/19.jpg)
Work productivity is nuanced…
Work performance – the ability to work with relative ease
or difficulty
Work productivity – the assessment of the quality and
quantity of work output
19 www.iwh.on.ca
![Page 20: Work Participation Outcome Measures · Brouwer et al.,: Relationships among work productivity concepts and health-related quality of life ... Work performance – the ability to work](https://reader035.fdocuments.us/reader035/viewer/2022070805/5f0394257e708231d409bed6/html5/thumbnails/20.jpg)
20
* Acronym definitions: WAI-Work Ability Index; QQ-Quantity and Quality Method; WPAI-Work Productivity and Activity Impairment/specific health
problem version; WPS-RA-Rheumatoid Arthritis-specific Work Productivity Survey (Tang et al., 2013 JRheum).
Global
Measures
Content/
Source
Concept Recall
Period
Disease
Attribution
Comparative
Referencing
Scaling
WAI* Item 1 Work ability Current None In relation to
lifetime best 0-10 (0=
completely unable to
work; assume best
work ability =10)
QQ Multiplication
of 2 items
How much
work performed
and the quality
of the work
Last work-
day
None (N/A) Compared to a
normal “work-
day”
Quantity: 0-
10 (practically
nothing to normal
quantity);
Quality: 0-10 (very poor to normal
quality)
WPAI
Item 5 Work
productivity
Last 7 days Can be
adapted to
any health
condition
None 0-10 (health
problem had no
effect on my work to
completely
prevented me from
working)
WPS-RA Item 4 Interference
with work
productivity
Last month Arthritis None 0-14 (no
interference to
complete
interference)
![Page 21: Work Participation Outcome Measures · Brouwer et al.,: Relationships among work productivity concepts and health-related quality of life ... Work performance – the ability to work](https://reader035.fdocuments.us/reader035/viewer/2022070805/5f0394257e708231d409bed6/html5/thumbnails/21.jpg)
21
++ = evidence from 2 or more studies, in the absence of conflicting evidence
+ = evidence from at least 1 study, and overall body of evidence supporting >refuting
(+) = estimates expected from an ongoing study; (+)* = not exclusively MSK
OMERACT
Truth
OMERACT
Discrimination
OMERACT
Feasibility
Global
measures
Face/content
validity
Construct
validity
Reliability Responsiveness RCTs Score
Interpretability
WPAI
(item 5)
++ ++ ++ ++ ++ + ++
WPS-RA
(item 4)
+ + ++ ++ ++ (+) ++
QQ + + ++ + + + ++
WAI
(item 1)
++ ++ ++ ++ (+)* + ++
![Page 22: Work Participation Outcome Measures · Brouwer et al.,: Relationships among work productivity concepts and health-related quality of life ... Work performance – the ability to work](https://reader035.fdocuments.us/reader035/viewer/2022070805/5f0394257e708231d409bed6/html5/thumbnails/22.jpg)
22
*Acronym definitions: WALS-Workplace Activity Limitations Scale; WLQ-25 (modPD)-Work Limitations Questionnaire with modified
physical demands scale (PD scale reoriented to be consistent with other subscales; with permission of developers [D. Lerner]) (Beaton et al., 2009)
Multi-item
Measures
Concept Scored Scales &
Number of Items
Time Frame
WALS* Amount/level of
difficulty
Summed score of 12
items
Not specified
WLQ-25 (modPD) Frequency/proportion
of time having difficulty
25 items: Physical
demands; Mental-
interpersonal; Time
management; Output
demands
Past 2 weeks
![Page 23: Work Participation Outcome Measures · Brouwer et al.,: Relationships among work productivity concepts and health-related quality of life ... Work performance – the ability to work](https://reader035.fdocuments.us/reader035/viewer/2022070805/5f0394257e708231d409bed6/html5/thumbnails/23.jpg)
23
++ = evidence from 2 or more studies, in the absence of conflicting evidence
+ = evidence from at least 1 study, and overall body of evidence supporting >refuting
(+)# = Trials ongoing. For WLQ, trials were negative and difference in WLQ was negative. Both WALS and WLQ have
evidence of discrimination between subgroups (one group improved; other not). Monitoring trial results is ongoing
OMERACT
Truth
OMERACT
Discrimination
OMERACT
Feasibility
Multi-Item
Measures
Face/content
validity
Construct
validity
Reliability Responsiveness RCTs Score
Interpretability
WALS ++ ++ ++ ++ (+)# + ++
WLQ-25 ++ ++ ++ ++ (+)# + ++
![Page 24: Work Participation Outcome Measures · Brouwer et al.,: Relationships among work productivity concepts and health-related quality of life ... Work performance – the ability to work](https://reader035.fdocuments.us/reader035/viewer/2022070805/5f0394257e708231d409bed6/html5/thumbnails/24.jpg)
Possible Work Outcome Contextual Factors
24 www.iwh.on.ca
![Page 25: Work Participation Outcome Measures · Brouwer et al.,: Relationships among work productivity concepts and health-related quality of life ... Work performance – the ability to work](https://reader035.fdocuments.us/reader035/viewer/2022070805/5f0394257e708231d409bed6/html5/thumbnails/25.jpg)
Thank you!
25 www.iwh.on.ca
![Page 26: Work Participation Outcome Measures · Brouwer et al.,: Relationships among work productivity concepts and health-related quality of life ... Work performance – the ability to work](https://reader035.fdocuments.us/reader035/viewer/2022070805/5f0394257e708231d409bed6/html5/thumbnails/26.jpg)