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Transcript of Why RDF for Healthcare Interoperability? - Yosemite …yosemiteproject.org/webinars/why-rdf.pdf ·...
![Page 1: Why RDF for Healthcare Interoperability? - Yosemite …yosemiteproject.org/webinars/why-rdf.pdf · Why RDF for Healthcare Interoperability? Part 2 of Yosemite Series David Booth,](https://reader031.fdocuments.us/reader031/viewer/2022030615/5adfb5987f8b9a6e5c8c7624/html5/thumbnails/1.jpg)
Why RDF for Healthcare Interoperability?Part 2 of Yosemite Series
David Booth, Ph.D.HRG / Rancho BioSciences
23-Jul-2015
Latest version of these slides: http://yosemiteproject.org/2015/webinars/why-rdf/
![Page 2: Why RDF for Healthcare Interoperability? - Yosemite …yosemiteproject.org/webinars/why-rdf.pdf · Why RDF for Healthcare Interoperability? Part 2 of Yosemite Series David Booth,](https://reader031.fdocuments.us/reader031/viewer/2022030615/5adfb5987f8b9a6e5c8c7624/html5/thumbnails/2.jpg)
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About the Speaker
David Booth, PhD, is a senior software architect at Hawaii Resource Group and at Rancho BioSciences, using Semantic Web technology to make clinical healthcare data interoperable between diverse systems. He previously worked at KnowMED, using Semantic Web technology for healthcare quality-of-care and clinical outcomes measurement, and at PanGenX, applying Semantic Web technology to genomics in support of personalized medicine. Before that he worked on Cleveland Clinic's SemanticDB project, which uses RDF and other semantic technologies to perform cardiovascular research. Prior to that was a software architect at HP Software. He was also a W3C Fellow from 2002 to 2005, where he worked on Web Services standards before becoming involved in Semantic Web technology. He holds a Ph.D. in Computer Science from UCLA.
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Outline
• What is RDF?
• Why RDF (in general)?
• Why RDF as a universal information representation for healthcare?
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What is RDF?
• "Resource Description Framework"
– But think "Reusable Data Framework"
• Language for representing information
• International standard by W3C
• Mature: 10+ years
• Used in many domains, including biomedical and pharma
![Page 7: Why RDF for Healthcare Interoperability? - Yosemite …yosemiteproject.org/webinars/why-rdf.pdf · Why RDF for Healthcare Interoperability? Part 2 of Yosemite Series David Booth,](https://reader031.fdocuments.us/reader031/viewer/2022030615/5adfb5987f8b9a6e5c8c7624/html5/thumbnails/7.jpg)
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PREFIX ex: <http://.../data/>PREFIX v: <http://.../vocab/>ex:patient319 v:fullName "John Doe" .ex:patient319 v:systolicBP ex:obs_001 .
ex:obs_001 v:value 120 .
ex:obs_001 v:units v:mmHg .
RDF Assertions (a/k/a "Triples")
![Page 8: Why RDF for Healthcare Interoperability? - Yosemite …yosemiteproject.org/webinars/why-rdf.pdf · Why RDF for Healthcare Interoperability? Part 2 of Yosemite Series David Booth,](https://reader031.fdocuments.us/reader031/viewer/2022030615/5adfb5987f8b9a6e5c8c7624/html5/thumbnails/8.jpg)
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PREFIX ex: <http://.../data/>PREFIX v: <http://.../vocab/>ex:patient319 v:fullName "John Doe" .ex:patient319 v:systolicBP ex:obs_001 .
ex:obs_001 v:value 120 .
ex:obs_001 v:units v:mmHg .
RDF Assertions (a/k/a "Triples")Subject Predicate
or PropertyObject
or Value
![Page 9: Why RDF for Healthcare Interoperability? - Yosemite …yosemiteproject.org/webinars/why-rdf.pdf · Why RDF for Healthcare Interoperability? Part 2 of Yosemite Series David Booth,](https://reader031.fdocuments.us/reader031/viewer/2022030615/5adfb5987f8b9a6e5c8c7624/html5/thumbnails/9.jpg)
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PREFIX ex: <http://.../data/>PREFIX v: <http://.../vocab/>ex:patient319 v:fullName "John Doe" .ex:patient319 v:systolicBP ex:obs_001 .
ex:obs_001 v:value 120 .
ex:obs_001 v:units v:mmHg .
RDF Assertions (a/k/a "Triples")Equivalent English sentence:
Patient319 has full name "John Doe".
![Page 10: Why RDF for Healthcare Interoperability? - Yosemite …yosemiteproject.org/webinars/why-rdf.pdf · Why RDF for Healthcare Interoperability? Part 2 of Yosemite Series David Booth,](https://reader031.fdocuments.us/reader031/viewer/2022030615/5adfb5987f8b9a6e5c8c7624/html5/thumbnails/10.jpg)
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PREFIX ex: <http://.../data/>PREFIX v: <http://.../vocab/>ex:patient319 v:fullName "John Doe" .ex:patient319 v:systolicBP ex:obs_001 .
ex:obs_001 v:value 120 .
ex:obs_001 v:units v:mmHg .
RDF Assertions (a/k/a "Triples")
Equivalent English sentence:Patient319 has a systolic blood pressure observation obs_001.
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PREFIX ex: <http://.../data/>PREFIX v: <http://.../vocab/>ex:patient319 v:fullName "John Doe" .ex:patient319 v:systolicBP ex:obs_001 .
ex:obs_001 v:value 120 .
ex:obs_001 v:units v:mmHg .
RDF Assertions (a/k/a "Triples")
Equivalent English sentence:Obs_001 has a value of 120.
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PREFIX ex: <http://.../data/>PREFIX v: <http://.../vocab/>ex:patient319 v:fullName "John Doe" .ex:patient319 v:systolicBP ex:obs_001 .
ex:obs_001 v:value 120 .
ex:obs_001 v:units v:mmHg .
RDF Assertions (a/k/a "Triples")
Equivalent English sentence:Obs_001 has units of mmHg.
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PREFIX ex: <http://.../data/>PREFIX v: <http://.../vocab/>ex:patient319 v:fullName "John Doe" .ex:patient319 v:systolicBP ex:obs_001 .
ex:obs_001 v:value 120 .
ex:obs_001 v:units v:mmHg .
RDF Assertions (a/k/a "Triples")
Sets of assertions form an RDF graph . . .
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PREFIX ex: <http://.../data/>PREFIX v: <http://.../vocab/>ex:patient319 v:fullName "John Doe" .ex:patient319 v:systolicBP ex:obs_001 .
ex:obs_001 v:value 120 .
ex:obs_001 v:units v:mmHg .
RDF Graph
RDF graph
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PREFIX ex: <http://.../data/>PREFIX v: <http://.../vocab/>ex:patient319 v:fullName "John Doe" .ex:patient319 v:systolicBP ex:obs_001 .
ex:obs_001 v:value 120 .
ex:obs_001 v:units v:mmHg .
RDF Graph
RDF graph
![Page 16: Why RDF for Healthcare Interoperability? - Yosemite …yosemiteproject.org/webinars/why-rdf.pdf · Why RDF for Healthcare Interoperability? Part 2 of Yosemite Series David Booth,](https://reader031.fdocuments.us/reader031/viewer/2022030615/5adfb5987f8b9a6e5c8c7624/html5/thumbnails/16.jpg)
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PREFIX ex: <http://.../data/>PREFIX v: <http://.../vocab/>ex:patient319 v:fullName "John Doe" .ex:patient319 v:systolicBP ex:obs_001 .
ex:obs_001 v:value 120 .
ex:obs_001 v:units v:mmHg .
RDF Graph
RDF graph
![Page 17: Why RDF for Healthcare Interoperability? - Yosemite …yosemiteproject.org/webinars/why-rdf.pdf · Why RDF for Healthcare Interoperability? Part 2 of Yosemite Series David Booth,](https://reader031.fdocuments.us/reader031/viewer/2022030615/5adfb5987f8b9a6e5c8c7624/html5/thumbnails/17.jpg)
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PREFIX ex: <http://.../data/>PREFIX v: <http://.../vocab/>ex:patient319 v:fullName "John Doe" .ex:patient319 v:systolicBP ex:obs_001 .
ex:obs_001 v:value 120 .
ex:obs_001 v:units v:mmHg .
RDF Graph
RDF graph
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PREFIX ex: <http://.../data/>PREFIX v: <http://.../vocab/>ex:patient319 v:fullName "John Doe" .ex:patient319 v:systolicBP ex:obs_001 .
ex:obs_001 v:value 120 .
ex:obs_001 v:units v:mmHg .
RDF Graph
RDF graph
![Page 19: Why RDF for Healthcare Interoperability? - Yosemite …yosemiteproject.org/webinars/why-rdf.pdf · Why RDF for Healthcare Interoperability? Part 2 of Yosemite Series David Booth,](https://reader031.fdocuments.us/reader031/viewer/2022030615/5adfb5987f8b9a6e5c8c7624/html5/thumbnails/19.jpg)
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Why RDF (in general)?
#5: RDF is self describing– RDF uses URIs as identifiers
#4: RDF is easy to map from other data representations– RDF data is made of assertions
#3: RDF captures information – not syntax– RDF is format independent
#2: Multiple data models and vocabularies can be easily combined and interrelated
– RDF is multi-schema friendly
#1: RDF enables smarter data use and automated data translation– RDF enables inference
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#5: RDF is self describing
• Uses URIs as identifiershttp://www.drugbank.ca/drugs/DB00945
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#5: RDF is self describing
• Uses URIs as identifiershttp://www.drugbank.ca/drugs/DB00945
drugbank: DB00945
Often abbreviated in RDF:PREFIX drugbank: <http://www.drugbank.ca/drugs/> drugbank:DB00945 . . . .
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#5: RDF is self describing
• Uses URIs as identifiershttp://www.drugbank.ca/drugs/DB00945
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Why is this important?
• Terms, data models, vocabularies, etc., can be linked to definitions
• Definition can be found by any party
– Reduces ambiguity
• Aids in bootstrapping new terms toward standardization
Supports standards and innovation
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#4: RDF is easy to map from other data representations
• RDF is made up of lots of small, atomic statements, called assertions or triples
• Easy to represent any data
• Easy to incorporate any data model
– Hierarchical, relational, graph, etc.
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Hierarchical data model in RDF
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Relational data model in RDF
ID fname addr
7 Bob 18
8 Sue 19
See W3C Direct Mapping of Relational Data to RDF:http://www.w3.org/TR/rdb-direct-mapping/
ID City State
18 Concord NH
19 Boston MA
People Addresses
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Why does this matter?
• Easy to map any data format to RDF
– E.g., XML, JSON, CSV, SQL tables, etc.
• Enables RDF to act as a universal information representation
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#3: RDF captures information – not syntax
• RDF is format independent
• There are multiple RDF syntaxes: Turtle, N-Triples, JSON-LD, RDF/XML, etc.
• The same information can be written in different formats
• Any data format can be mapped to RDF
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Different source formats, same RDF
OBX|1|CE|37270^BPsystolic, sitting||120||mmHg|
<Observation xmlns="http://hl7.org/fhir"> <system value="http://loinc.org"/> <code value="37270"/> <display value="BPsystolic, sitting"/> <value value="120"/> <units value="mmHg"/></Observation>
HL7 v2.x FHIR
RDF graph
Maps to
Maps to
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Why does this matter?
• Emphasis is on the meaning (where it should be)
• RDF acts as a universal information representation
– Different formats can be exchanged with the same meaning
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RDF as a universal information representation
OBX|1|CE|37270^BPsystolic, sitting||120||mmHg|
HL7 v2.x
<Observation ...> <system value="http://loinc.org"/> <code value="37270"/> ...</Observation>
FHIR
RDF
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Why does this matter?
• Helps avoid the bike shed effect in standards, a/k/a Parkinson's Law of Triviality
– Standards committees often spend hours arguing over syntax and naming -- irrelevant to computable information content
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Bike shed effecta/k/a Parkinson's Law of Triviality
Organizations spend disproportionate timeon trivial issues. -- C.N. Parkinson, 1957
2. Bike ShedCost: $1,000
Discussion: 45 minutes
1. Nuclear PlantCost: $28,000,000
Discussion: 2.5 minutes
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@@ TODO: Add slide showing two computers thinking RDF @@
• TODO: Maybe also add a slide showing how data can be added without breaking clients
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#2: Multiple data models and vocabularies can be easily combined
and interrelated
• RDF is multi-schema friendly*
• Multiple data models/schemas and vocabularies can peacefully co-exist, semantically connected
*A/k/a schema-promiscuous, schema-flexible, schema-less, etc.
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Multi-schema friendly
HomePhone Town ZipPlus4 FullName Country Address FirstName LastName Email
City ZipCode
Red Model Blue ModelGreen Model
Country
subClassOf
sameAshasLast
hasFirst
Multiple models peacefully co-exist
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Multi-schema friendly
• Blue app sees Blue model
HomePhone Town ZipPlus4 FullName Country Address FirstName LastName Email
City ZipCode
Red Model Blue ModelGreen Model
CountryCountry Address FirstName LastName Email
City ZipCode
Blue Model
Country
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Multi-schema friendly
• Red app sees Red model
HomePhone Town ZipPlus4 FullName Country Address FirstName LastName Email
City ZipCode
Red Model Blue ModelGreen Model
CountryHomePhone Town ZipPlus4 FullName Country
Red Model
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Multi-schema friendly
• Green app sees Green model
HomePhone Town ZipPlus4 FullName Country Address FirstName LastName Email
City ZipCode
Red Model Blue ModelGreen Model
CountryHomePhone Town ZipPlus4 Country FirstName LastName Email
Green Model
Country
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Why is this important?
• Different formats, data models and vocabularies can be:
– used together harmoniously
– semantically linked
• New ones (or new versions) can be gracefully incorporated
– Healthcare vocabularies are revised ~3-8% per year
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Different views for different systems
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Different views for different systems
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Different views for different systems
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#1: RDF enables smarter data use and automated data translation
• RDF enables inference
• Inference derives new assertions from old
– "Entailments"
• Query for v:HeartValve surgeries can find v:MitralValve surgeries
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Inference example
• If you know:?x a v:MitralValve .v:MitralValve rdfs:subClassOf v:HeartValve .
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Inference example
• If you know:?x a v:MitralValve .v:MitralValve rdfs:subClassOf v:HeartValve .
• You can infer:?x a v:HeartValve .
Infer
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Inference example: sameAs
• If you know: Town
• You can infer: City (or vice versa)
HomePhone Town ZipPlus4 FullName Country Address FirstName LastName Email
City ZipCode
Red Model Blue ModelGreen Model
subClassOf
sameAshasLast
hasFirst
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Inference example: composition
• If you know: FirstName + LastName
• You can infer: FullName
– But not necessarily vice versa
HomePhone Town ZipPlus4 FullName Country Address FirstName LastName Email
City ZipCode
Red Model Blue ModelGreen Model
subClassOf
sameAshasLast
hasFirst
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Why is this important?
• Smarter data use
– Query for v:HeartValve surgeries can find v:MitralValve surgeries
• Automated data translation
– Red Model data + Blue Model data => Green Model data
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Translation as inference
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Translation as inference
Translate
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Why RDF as a universal information representation
for healthcare?
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Standard Vocabularies in UMLS
AIR ALT AOD AOT BI CCC CCPSS CCS CDT CHV COSTAR CPM CPT CPTSP CSP CST DDB DMDICD10 DMDUMD DSM3R DSM4 DXP FMA HCDT HCPCS HCPT HL7V2.5 HL7V3.0 HLREL ICD10 ICD10AE ICD10AM ICD10AMAE ICD10CM ICD10DUT ICD10PCS ICD9CM ICF
ICF-CY ICPC ICPC2EDUT ICPC2EENG ICPC2ICD10DUT ICPC2ICD10ENG ICPC2P ICPCBAQ ICPCDAN ICPCDUT ICPCFIN
ICPCFRE ICPCGER ICPCHEB ICPCHUN ICPCITA ICPCNOR ICPCPOR ICPCSPA ICPCSWE JABL KCD5 LCH LNC_AD8 LNC_MDS30 MCM
MEDLINEPLUS MSHCZE MSHDUT MSHFIN MSHFRE MSHGER MSHITA MSHJPN MSHLAV MSHNOR MSHPOL MSHPOR MSHRUS MSHSCR MSHSPA MSHSWE MTH MTHCH MTHHH MTHICD9 MTHICPC2EAE
MTHICPC2ICD10AE MTHMST MTHMSTFRE MTHMSTITA NAN NCISEER NIC NOC OMS PCDS PDQ PNDS PPAC PSY QMR RAM RCD
RCDAE RCDSA RCDSY SNM SNMI SOP SPN SRC TKMT ULT UMD USPMG UWDA WHO WHOFRE WHOGER WHOPOR WHOSPA
Over 100!
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Each standard is an island
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How RDF helps standardize the standards
• Meaning of each standard can be captured in RDF (& family)
– RDF as a universal information representation
• Encourages clarity and consistency
• Enables semantic linkage between standards
• Allows distributed extensibility and late linkage
• Facilitates standards convergence
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Bridging healthcare standards
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Bridging healthcare standards
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Summary: Why RDF?Standardizing the Standards
How RDF helps:
• Captures information content, regardless of data format
• Allows multiple data models to co-exist, interlinked
• Enables linkage between standards
• Facilitates standards convergence
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Summary: Why RDF?Crowdsourcing Translations
How RDF helps:
• Facilitates automated data translation, for:
– Legacy data formats and models
– Versioning standards
– Diverse use cases
• Common basis for crowdsourcing translation rules
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Summary: Why RDF?
The "best available candidate" for a universal information representation
– See Yosemite Manifesto
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Upcoming webinars
• Aug 6 - drugdocs: Using RDF to produce one coherent, definitive dataset about drugs, Conor Dowling, Caregraf - Part 3 of Yosemite Series
• Sept 3 - Linked VistA: VA Linked Data Approach to Semantic Interoperability, Rafael Richards, Veterans Affairs - Part 4 of Yosemite Series
• Sept 17 - Clinical data in FHIR RDF: Intro and Representation, Josh Mandel, Children's Hospital Informatics Program at Harvard-MIT, and David Booth, HRG - Part 5 of Yosemite Series
• Others to be announced
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Join the announcements list
http://YosemiteProject.org/
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Join the announcements list
http://YosemiteProject.org/
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Questions?
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BACKUP SLIDES
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De jure versus de facto standards
• De facto standards evolve faster than de jure standards
• RDF supports both