What does Sefar have to do

with your breakfast ?

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7

Preserving

agents

Chemical

Industry

Coffee filter

Filter Elements

Light

Architecture

Diagnostics

Healthcare

Cutlery

Mining

Industry

Sugar

Food

Water

Environment

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Marketing

& Sales

Application

Engineering

Manufacturing

Synthetic Filter

Products

Core Competencies

- weaving

- finishing

- making-up

- large product range on stock

- application know-how

- customized products

- global distribution

network

- corporate identity

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Filtration Worldwide

Sales Office

Fabrication

Mesh&Fabric

Production

Filtration

Separation of solids from liquids = wet filtration

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Little Filtration Guide

1. Overview Solid-Liquid Separation

2. Cake-Filtration

3. Overview Filter Media

4. Woven Filter Media

5. Filter Solution

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Filtration Overview

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No cake formation !

Dead-end filtration Cross-flow filtration

Filtration Overview

Depth Filtration Surface Filtration

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Cake Filtration

bridge building

Filter cake

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Filtration by size

Membranes

Needlefelts

Woven fabrics

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Woven

Filtermedia

Non-Woven

Filtermedia

Filtration / Separation

Media

Monofilament Fabrics

Multifilament Fabrics

Staple Fiber Fabrics

Knitted Fabrics

Needlefelts

Fleece

Sinterproducts

Membranes

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Woven Filter Media => Fibers

monofilament

yarn

multifilament

yarn

staple fiber

yarn

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Woven Filter Media => Weave patterns

plain twill PRD = plain

reverse dutch

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Finishing: Adapted For The End Use

Washing

Pre - shrinking

Pre - stretching

Heat - setting

Antistatic treatment

Customer-specific

treatments

Calendering

Dyeing

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Product Rangemesh opening: 1 - 5000 µm

wire diameter: 24 - 1000 µm

1400 different open mesh fabrics

400 different filtration fabrics

Thousands of tailor-made fabrics and made-up

products

PA monofilament: Ø 24 µm

human hair: Ø 65 µm

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Filtration solutions

Customers requirements generally involve

Specific industry requirements

Filter machines and separation systems

Process Technology

Filter media and fabrication

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Typical general requirements

Mechanical and chemical stability

Life-time

Filter efficiency

Capacity

No clogging

Good cake release and cleanability

Filter performance

Easy maintenance and filter change

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Filter Equipment

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Focus on Industry Life Science / Pharma

Sefar customized filter solutions for Pharma API

Manufacturing / wet Filtration

Wet Process Separation including Chemical Synthesis,

Fermentation & Extraction

Liquid Product Polishing

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Focus on Equipment

Important separation equipment with filter media

Liner or Peeler

Centrifuge

Bag Centrifuge Filter NutscheHeinkel

Inverting Filter

Centrifuge

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Polymer Choice

Standard -> polypropylene

Good chemical resistance

Broad resistance to acid and caustic mixture

Reasonable temperature resistance

Some alternatives available in PHARMA-Grade:

Polyester

Polyamide

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Polymer Choice

use of high performance materials like

PEEK, PTFE

high temperature resistance

where overheated steam

(sterilisation) or extreme

drying conditions are required

best chemical resistance

PEEK material available for

best food and bio-compatibility

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Fabric solutions

SEFAR TETEX MONO optimal particle retention

good defined pore size

pure surface / cake filtration

less clogging

easy cleaning

SEFAR TETEX MULTI good mechanical resistance

recommended for structure parts

smallest particles retained

due to some depth filtration

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Fabric Solution

Clogging / Cleaning Issues

Monofilament Fabric

Multifilament Fabric

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Fabric Solution

SEFAR TETEX DLW

optimal particle retention

good defined pore size

pure surface / cake filtration

less clogging

easy cleaning

easier installation / maintenance

better mechanical resistance

included support / drainage

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Fabric Solution

SEFAR TETEX DLW

avoids wrinkles and reduces dilatation

reduces installation, maintenance time

integrated backing support with drainage function

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Fabric solution

Proposed selection of fabrics for Life Science and Pharma

SEFAR PHARMA Grade Fabrics

Most are successfully used since years in pharmaceutical

application

Others have been optimized for the specific requirements

FDA conformity and extraction tests are defined as

standard specifications

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Fabrication Liner Centrifuge

Liners available for all models of horizontal or vertical peeler

centrifuge

Drop-In ready

liners

DLW-liners ideal

for peeler units

with minimum

plow tolerances

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Fabrication Liner Centrifuge

Seal design adapted to your

centrifuge filter machine

1 filter fabric

2 support fabric

3 ultrasonic contiweld

4 TETEX DLW options

1

2

1

2

1

2

1

2

4 4

3

a b c d e f

1 2

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Special requirements from Life Science

and pharmaceutical industries

Certifications (FDA conformity)

Traceability

Consistency of specs

Cleanliness

Easy handling

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PHARMA Grade fabrication

introduction of new fabrication standards in order to avoid

additional contamination of the fabricated filters

central registration of all used supply items and

accessories

all items in contact with product are either FDA-compliant

or limited in quantity to ensure extractable levels do not

exceed a tolerable limit of 1500 mg/m2.

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Sefar GMP Guidelines for

PHARMA-Fabrication

Introduction of specific Guidelines that control

Cleanliness / Sanitary control

Quality control / Final inspection

Manufacturing Documentation / Work Instructions

Employee Training

Fabrication Sites

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Adapted Fabrication procedures

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Enhanced Final Inspection

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Restriction of supply items

Only specifically registered items are allowed in PHARMA

fabrication

All product contact items are in conformity with FDA or their

use is limited so that extractable levels do not exceed a

tolerable level of total 1500 mg/m2

If conform items are available on the market they will replace

non conform items immediately after positive technical

evaluation

example FDA-conform glue to cover pin holes on fluid bed

dryers

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Extraction proceduresSame as for fabrics !

Based on the extractions according to FDA-regulations

(FDA CFR title 21 part 177) for PES and PA

Extraction solvents:

Ethanol 50% Soxlet at total reflux

Ethanol 96% Soxlet at total reflux

Petrol-Ether Soxlet at total reflux

Water (120°C)

For the routine extraction the extraction with maximum result

but without extraction of oligomers is chosen

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Fabrication Documentation

Manufacturer specific inspection report O /

PHARMA Fabrication

DIN 55350 – 18 – 4.2.1

specification sheet including the fabric certifications

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PHARMA-Grade packing

Easy identification as a Sefar quality product

Every single item is

wrapped separately

in PE-foil and stored

in the PHARMA box

Reusable PHARMA box

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PHARMA labelling

Ultrasonic-welded text

for identifiction and tracing

Non Fading

Non Shedding

No introduction of

additional foreign material

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Welding in Fabrication

After thorough evaluation and testing of newest technologies

we replace sewing with optimal welding technologies

(replacement of existing articles only after checking back

with the end user)

No stitching holes

No shedding of fibers from the sewing yarn

No attack of the joint through abrasion

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Hungry for more ?

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