University of Washington WERA Update 2009 Steven Roberts

•Pathogens

•Shellfish Genomics

Pathogens

• Vibrio tubiashii

Vibrio tubiashii

226 million bp

Vibrio tubiashii

chitinase, serine protease, RSE

Genomics

• Basics

• Crassostrea gigas

• Disease Tolerance

• Crassostrea virginica

• Haliotis cracherodii

• Mercenaria mercenaria

C. gigas plated hemocytes

Roberts et al 2009

C. gigas plated hemocytes

Roberts et al 2009

C. gigas Vibrio challenge

Roberts et al 2009

C. gigas Vibrio challenge

Roberts et al 2008

C. gigas Vibrio challenge

ProstaglandinE2 receptorEP4 subtype

Prostaglandins

Gavery; Poster

Value-added

Disease Resistance

• C. virginica

• H. cracherodii

• M. mercenaria

C. virginica

H. cracherodii

H. cracherodii

M. mercenaria

photo: Dale Leavitt (RWU)

Other stuff

• Epigenetics (methylation)

• Gene annotation effort? (wiki)