Welcome to LEWA Process Technologies, Inc. · Version Sept. 2014 Rev. 6 Welcome to LEWA Process...
Transcript of Welcome to LEWA Process Technologies, Inc. · Version Sept. 2014 Rev. 6 Welcome to LEWA Process...
Version Sept. 2014 Rev. 6
Welcome toLEWA Process Technologies, Inc.
LEWA Center Of Excellence for High Purity– Devens, MA
LEWA Process Technologies; LEWA PT Business Overview. .
Version Sept. 2014 Rev. 6
Agenda
– Corporate Structure – Main Groups: Nikkiso – LEWA – LEWA PT
– LEWA Group – Global Look at LEWA Products
– LEWA Process Technologies, Inc. “Clean Market”
– Example Systems Produced by LPT
– Example Systems Produced by LEWA GmbH for Clean Market
LEWA Process Technologies; Introduction to our company 2
Nikkiso Factsheet
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NIKKISO CO., LTD.
Executive Management
Headquarters
Date of Establishment
Registered Capital
Net Sales (cons.) March 2013
No. of employees
Stock Exchange Listing
Core business
Toshihiko Kai, President & CEO
Yebisu Garden Place Tower
Tokyo 150-6022, Japan
December 26, 1953
6,544 million yen
104,000 million yen (consolidated)
5,411 (consolidated)
First Section of Tokyo Stock
Exchange
80,286,464 issued shares
Industrial Division
Aerospace Division
Precision Equipment
Medical Division
LEWA-Nikkiso Industrial Division (pumps + systems) – Factsheet
9/17/2014© LEWA GmbH 4
LEWA-Nikkiso Industrial Division
Executive Management
Naota Shikano (CEO),
Dr.-Ing. Martin Fiedler (COO)
Stefan Glasmeyer (CMO)
HeadquartersLEWA GmbH,
Leonberg / Germany
Net Sales (cons.)
March/2013
Thereof LEWA USD 280 m
Add. LPT USD 10 m
No. of employees
2,088 in total
560 in Germany of LEWA
520 in Japan of NIKKISO
768 Intl. of LEWA & NIKKISO
75 LEWA Process
Technologies
Core business
Chromatography Systems
Reciprocating pumps
Canned motor pumps
Cryogenic pumps
Metering & conditioning
systems Services
Geveke
IPT >> LEWA Process Technologies affiliates Nikkiso
LEWA
affiliates
Original
Manufacturers,
system integrators,
sales / service
engineers
Places
Reciprocating
Pumps
Systems &
Packages
Canned Motor
Pumps
Cryogenic
Pumps
Partner
Products
Services &
Aftersales
LEWA-Nikkiso Business
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Core Business Strategic Business
Clean
MarketsOil & Gas
Upstream
Process Industry
& Downstream Utilities
Package
Diversification
LNG supply chain
markets
LEWA-Nikkiso Industrial Division – Overview
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Customer Solutions
Various Applications of
– Pharmaceutical
– Personal Care
– Food
– Beverages
– Oil & Gas
– Chemicals
– Petrochemicals
– Plastics
– Cleaning
– Detergents
– Energy
– Environment
– Other IndustriesWater Treatment
LEWA ecoflowNikkiso Non-
Seal Pump
LEWA diaphragm
process pump
Geveke N2 generation
Exclusive rights in
many regions for
Partner Products
Nikkiso Cryogenic
EcoPrime LPLC
affiliates
Original
Manufacturers,
system integrators,
sales / service
engineers
Products
LEWA Process Technologies – Factsheet(Former Integrated Process Technologies)
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Jim Banks (CEO)
Christopher Sandusky (CTO)
Gerard Gach (CMO)
US Devens, MA
2000
100% subsidiary of LEWA-
Nikkiso America, Inc.
EUR 7.6 m ($10.4 m)
75
Bio / pharmaceutical
Personal Care
Fine Chemical
Systems engineering and
services integrating
– Process expertise
– Fabrication
– Automation
– Installation Services
LEWA Process Technologies, Inc.
Executive Management
Headquarters in
Date of Establishment
Ownership
Net Sales (cons.) 2013
No. of employees
Target markets
Core business
Version Sept. 2014 Rev. 6
Agenda
– Corporate Structure – Main Groups: Nikkiso – LEWA – LEWA PT
– LEWA Group – A Global Look at LEWA Products
– LEWA Process Technologies “Clean Market”
– Example Systems Produced by LPT
– Example Systems Produced by LEWA GmbH for Clean Market
LEWA Process Technologies; Introduction to our company 8
LEWA Group
LEWA Milestones – from Family Business to International Group
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1952
First ACHEMA G4T – biggest process
diaphragm pump
Company
Foundation
Integration LEWA-
NikkisoAcquisition of
Integrated
Process
Technologies,
Inc.
First Patent LEWA ecoflow DBAG and Quadriga
Capital acuire LEWAStrategic Business
Diversification in
„Clean Markets“
New Management for
Strategy 2018+
1953 1954 1955 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013…
Record Project
USD 40 m
Integrated
Process Technologies,
Inc. Founded 2000
LEWA; System Integrator and Engineering Services
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© LEWA Process Technologies, Inc.
10
LEWA Systems
LEWA-Nikkiso acts as a system integrator and global packager for Industrial and Clean Markets
LEWA Process Technologies acts as a system integrator and engineering services specializing in the Life
Sciences and Regulated Industries globally leveraging LEWA- Nikkiso companies
We combine mechanical engineering, fluid dynamics, electrical control, large-scale fabrication, and project
management know-how.
LEWA Systems Capability
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LEWA ecofoam®
System for metering various blowing
agents in plastic manufacture in
combination with extruders
LEWA EcoPrime®
Chromatography system with innovative,
mechatronic drive and hygienic
diaphragm metering pumps
LEWA odorizing system
LEWA has built odorizing systems for over
40 years, e.g., for natural gas, oxygen,
nitrogen and carbon dioxide
Buffer Inline Dilution
System to mix all ingoing fluids, e.g. prior
to a chromatography system
Nitrogen Generation
Industry-scale, custom-designed
membrane-type package with very low
lifecycle costs
LEWA production unit
Customer specific batch/continuous
systems for production processes
Chemical Injection Package
Customer specific packages for
chemical injection in the oil and gas
industry
OEM Systems
Systems designed and fabricated for OEM
clients in Clean Process Industry
LEWA Process
Technologies Products
LEWA Process
Technologies Products
LEWA Process
Technologies Products
LEWA Group:Industrial Division – Order Bookings Split 2013 by Industry in %
9/17/2014© LEWA Process Technologies, Inc. 12
Oil & Gas
39
Refinery,
Petrochemicals,
Chemicals
32
Clean
Markets*
10
Plastic,
Ceramic,
Textiles
11
Power Plants
& Nuclear
5
Others
6
* Does not reflect full Clean Market supply; OEM business not fully recognized.
„Number 1 in ‘Creating Fluid Solutions’
for all customers in our target markets.“
LEWA Group Vision: “No. 1 in Creating Fluid Solutions”
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...Solutions
We understand customer’s
processes and identify their
respective “pain points”.
Therefore we offer complete
systems backed by high-
quality life-cycle services.
Creating...
“Creating” suits the brand
personality of LEWA as an
ambitious maker and
creative manufacturer, who
goes beyond (technological)
boundaries.
...Fluid...
“Fluid” designates the core
business. LEWA doses,
injects, conveys, mixes, fills,
separates and heats or
cools liquids and knows how
to handle critical fluids in all
states as well as their
interactions with materials.
LEWA: Focus on own Research & Development
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Structured Innovation Management
– Internal R&D department works independently
of our daily business
– Structured process for innovation management in place
– Various patents in place
– Knowledge network with universities
– Test stand - process pumps:
max. ca. 350kW hydraulic power
– Latest software tools in use
– CAD solid edge
– Electrical design
– Finite element analysis (FEM): ANSYS
– Computational fluid dynamics (CFD): CFX
– Computer aided measurement
LEWA Group Hub Subsidiaries
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LEWA Process Technologies
– Engineering
– Fabrication
LEWA-Nikkiso
America, Inc.
– Sales
– Engineering
– Fabrication
LEWA Bombas, Brazil
– Sales
– Engineering
– Fabrication
LEWA S.R.L.
– Sales
– Engineering
– Fabrication
LEWA Middle East FZE
– Sales
– Engineering
– Fabrication
Nikkiso Pumps
Korea Ltd.
– Sales
LEWA China
– Sales
– Engineering
– Pump production
– Fabrication
LEWA GmbH
Headquarters
Industrial Division
– Sales
– Engineering
– Pump production
– Fabrication
Nikkiso Co., Ltd.
Group
Headquarters
LEWA PTE LTD
– Sales
– Engineering
– Fabrication
Geveke
– Sales
– Engineering
– Fabrication
LEWA Group Service – Worldwide
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Service Portfolio
– Customer service
– Repairs
– Commissioning
of equipment
– Health checks
– Spare parts
– Fast and worldwide
– Maintenance contracts
– Revamping of
entire systems
– Fluid evaluation
– Internal and external seminars
for users
Certificates, Memberships, Standards within LEWA Corporation
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Member of VDMA
e.V. (Association
of German
Machine and Plant
Engineering)
Member of ISPE
International
Society for
Pharmaceutical
Engineering
Member of the
Europump
Organization
Member of the
VDMA e-market
Member of
the Hydraulic
Institute
Member of
network of
competence
process
engineering
Pro3 e.V.
Material ac-
cording to U.S.
Food and Drug
Administration
GOST-R
Export-certificate
for Russia
Pumps according
to guidelines:
API 674 and
API 675
Registered at
FPAL First Point
Assessment
Certified
according to
DIN EN ISO 9001
TÜV SÜD
Member of
DIN e.V. (German
Institute for
Standardization)
Partner of the
Engineering
Industry
Sustainability
Initiative
Member of
Cleaning
Excellence
Center
Pumps according
to guidelines of
the European
Hygienic
Engineering &
Design Group
Version Sept. 2014 Rev. 6
Agenda
– Corporate Structure – Main Groups: Nikkiso – LEWA – LEWA PT
– LEWA Group – Global Look at LEWA Products
– LEWA Process Technologies “Clean Market”
– Example Systems Produced by LPT
– Example Systems Produced by LEWA GmbH for Clean Market
LEWA Process Technologies; Introduction to our company 18
LEWA Process Technologies, Inc.
More information at www.lewapt.com
“LPT”
• New name,
• New brand,
• New website
www.lewapt.com
September 2014
The Product Structure of LEWA Process Technologies, Inc.
9/17/2014© LEWA Process Technologies, Inc. 20
LEWA Process Technologies, Inc. - Products & Services
Our Offerings
Professional
Services /
Design – Build
Engineering
LPLC, HPLC
Chromatography
Systems
Batch to
Continuous
Processing
Systems
OEM &
Custom
Engineered
Products
Automation
Field Piping &
Installation
Example of our work: Purification Systems
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LEWA EcoPrime® LPLC
– Custom-designed
chromatography system
– Pressure: 0.04 l/min
up to 33.1 l/min
(EcoPrime 500)
– Flow rate: up to 10 bar
– Precise flow rate with
minimum pulsation
– Dynamic flow range 1:150
– Low holdup volume
– 0.5 to 99.5% step and linear
gradient capability
– Low shear to process
biomolecules
– Target markets:
pharmaceutical
and biopharmaceutical
LEWA Process Technologies, Inc.
Our Purpose
To become the world’s leading
innovator of systems that reinvent the
downstream processing of critical
fluids.
Our Value Proposition
LEWA Process Technologies is the
only company that combines deep
expertise in fluid dynamics with
proven pump technology to engineer
advanced systems that move fluids
with unmatched precision,
reproducibility, flexibility and
efficiency.
We work with you…
…to provide them with the industry’s most
advanced and well-engineered fluid processing
platforms so they can create products with
unmatched precision and efficiency.
Processing
Brilliance.
We are:
Innovative
End-to-end
Nimble
Precise
Reproducible
Flexible
Accurate
Experienced
Processing Brilliance
Customer Base & Industry Requirements
9/17/2014LEWA Process Technologies CONFIDENTIAL Use of logo or name does not imply endorsement. Logo‘s are property of respective companies. 23
Industry Requirements
– Software with ease of
validation.
– High metering accuracy
(recipe consistency)
– Good repeatability (HACCP)
– High reliability
– Gentle to the product
– Good cleanability to ensure
food safety, CIP, SIP
– Use of approved material
and lubricants (FDA, NSF)
– Hygienic pump selection
for critical application
(EHEDG)
Representative List of Customer Base
Work Flow For LEWA Process Technologies - our Strength, Your Benefit
LPT maintains a full compliment of departments that ensure the project has the right resources
9/17/2014© LEWA Process Technologies, Inc. 24
A clear differientiator from
other ”suppliers”.
– Complete array of expertise
to ensure comprehensive
management of the design
– Process experts at each
step.
Process Engineering
Mechanical/Design/CAD Engineering
Automation Engineering
Manufacturing / Fabrication
1
2
3
Project Mangement
QA/QC
Constant Customer Interface
Field
Installation /
Service
4
Subject
Matter
Experts
The Well Defined Project Work
Flow at LEWA Process
Technologies Assures a Quality
End Product.
Full workflow charts available for
review within on site audit meetings© LEWA Process Technologies, Inc. Confidential - Non Controlled Copy
On Spec.
On Budget.
On Time.
Custom Specialists.
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Getting you what you want –
LEWA Process Technologies
understands the best system is designed
to your standard.
We are experts in custom design
systems.
Engineering Services.
9/17/2014© LEWA Process Technologies, Inc. 27
LEWA Process Technologies is long
known for unique insights into high purity
processes.
A comprehensive staff of process
engineers, project manages, automation
engineers, world class fabrication and on
site installation sets LEWA Process
Technologies apart from others.
Downstream Expertise.
9/17/2014© LEWA Process Technologies, Inc. 28
LEWA Process Technologies
understands downstream and creates
value through reduction in footprint,
batch to batch reproducibility and
precision that results in yield
improvement.
Ingenuity with process integrity is our
commitment.
Version Sept. 2014 Rev. 6
Agenda
– Corporate Structure – Main Groups: Nikkiso – LEWA – LEWA PT
– LEWA Group – Global Look at LEWA Products
– LEWA Process Technologies “Clean Market”
– Example Systems Produced by LPT
– Example Systems Produced by LEWA GmbH for Clean Market
LEWA Process Technologies; Introduction to our company 29
Application Example: Bulk Filling Station
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USA (Pharma Production
facilities), multiple units
delivered since 2011
Location
Application
Filling intermediate and bulk liquid
drug substances from 0.2 to 5.0L
in microbial controlled semi
automated portable station with
built in weighing.
LEWA Process Technologies
original design in concert with
major biopharmaceutical
company.
LEWA solution
Application Example: Continuous Processing
9/17/2014© LEWA Process Technologies, Inc. 31
USA (Biopharma Process
Development facilities).
Delivered 2014
Location
Application
Multiple purification processes
linked to performed continuous
processing of protein based
therapies under development.
LEWA Process Technologies
original design in concert with
major biopharmaceutical
company. LPT automation,
system design and manufacture.
LEWA solution
Application Example: Chromatography Systems Processing
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Asia
Delivered 2014
Location
Application
Low Pressure Chromatography
skids for monoclonal antibody
production for GMP production.
LEWA original design in concert
with major biopharmaceutical
company. Employed LEWA
Intellidrive EcoDos pumps with
system design and manufacture
by LPT.
LEWA solution
Application Example: Ultrafiltration Processing System
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EU, USA, Asia (Multiple
Biopharma Facilities).
Delivered series of units starting
2008
Location
Application
Hollow Fiber Membrane
production skid for GMP
production.
LEWA OEM design for major life
sciences technology supply
company. LEWA Process
Technologies design and
manufacture based on OEM
supplied concept.
LEWA solution
Application Example: Membrane Purification System
9/17/2014© LEWA Process Technologies, Inc. - Confidential 34
USA (Biopharma Facilitiy).
Delivered 2011
Location
Application
Hollow Fiber Membrane
production skid for GMP
production.
LEWA original design for major
biopharmaceutical company.
Employed LEWA EcoDos pumps
with system design and
manufacture by LPT.
LEWA solution
Application Example: Centrifuge System
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USA (Biopharma Facilitiy).
Delivered 2014
Location
Application
Clarification of biologic in a GMP
production plant.
OEM centrifuge complimented
by LEWA design and
manufacture for a
biopharmaceutical company.
Employed LEWA pumps.
LEWA solution
Application Example: Buffer Dilution System
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USA (GMP Bio/pharma Facility).
Delivered 2009
Location
Application
Buffer preparation for
pharmaceutical manufacturing
processing
LEWA Process Technologies
design and manufacture purpose
built to meet A&E design.
Manufactured, FAT and
disassembled for shipping and
re-assembly on customer site.
LEWA solution
~60 ft (19 m)
~10 ft
(3 m
)
Application Example: Hydrogen Storage; Utility Support
9/17/2014© LEWA Process Technologies, Inc. - Confidential37
Installation in Germany (Clean
Energy Site) in 2015
Manufactured in USA at LPT in
2014
Location
Application
Storage of wind energy in form of
hydrogen.
LEWA Process
Technologies design and
manufacture purpose built
to meet customer design.
Fabricated in the mobile
container for shipping and
operation with at the
customer site.
LEWA solution
Version Sept. 2014 Rev. 6
Agenda
– Corporate Structure – Main Groups: Nikkiso – LEWA – LEWA PT
– LEWA Group – Global Look at LEWA Products
– LEWA Process Technologies “Clean Market”
– Example Systems Produced by LPT
– Example Systems Produced by LEWA GmbH for “Clean" Market
LEWA Process Technologies; Introduction to our company 38
Application Example: Production of Powder
9/17/2014© LEWA GmbH, LEWA v1.0 39
Germany (R&D facilities),
delivered in 2006
Location
Application
Production of powder by spray
drying system with hot food or
plastic melts, supercritical CO2
160 l/h, 320 l/h @ 350 bar
Temperature controlled pumps,
LEWA ecoflow LDE3
LEWA solution
Application Example: Production of aromatized water
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France, delivered in 2007
Location
Dosing of aroma for the production
of aromatized water
15 l/h @ 10 bar
– LEWA ecodos metering pump
– Mass flow meter
and pressure gauge
– SPS-controlled dosing system
Application
LEWA solution
Application Example: Continuous Blending
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Germany, delivered in 2001
Location
Continuous blending of gelatine,
aroma, colorant and citric acid
2.5 t/h @ 6 bar
– LEWA plunger pump
– Vessels
– Mass flow meters
– Electrical control
Application
LEWA solution
Application Example: Liquid Metering for Pharma Extruder
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Germany, Puerto Rico, USA,
delivered in 2006, 2007
Location
Application
Liquid metering for pharma
extruder application
– Complete system with
impeller type mixer, control
system, LEWA ecoflow LDB
– Designed according all
qualification and validation
steps (cGMP, GAMP)
LEWA solution
Application Example: Production of Buffer for Protein Purification
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Germany, delivered 2008
Location
Application
Production of buffer and protein
solution, water for injection
15 – 800 l/h, 60 – 2,100 l/h
@ 6 bar
Entire system, LEWA ecodos
hygienic with multiplex heads,
frequency converter, multiphase
motor and control system
LEWA solution
LEWA Process Technologies, Inc. benefits:
9/17/2014© LEWA GmbH, filename, purpose 44
– Global strength, financial security of LEWA-Nikkiso
– History of ingenuity and execution in GMP
environments
– Full service design – engineering – fabrication –
installation; not just a supplier or A&E but a single
point vertical supplier from concept to on-site
implementation
– Automation, Process Engineering, Mechanical
Design, Fabrication all under one roof assures
commercial and technical project certainty
– Our customer auditing successes illustrate an
environment of attention to quality and an
environment in tune with GMP customer expectations
– Your partner of choice for programs that demand high
precision, reliable performance using the best in class
engineering experience and practice
Version 2014 Rev. 6
Thank you!
Visit www.lewapt.com for more information on
LEWA Process Technologies, Inc.
Join us on
LEWA Process Technologies; Introduction to our company
Version Sept. 2014 Rev. 6
Addenda Slides
The following slides may enhance your understanding of LEWA
Process Technologies.
These are supplied for additional information.
LEWA Process Technologies; Introduction to our company 46
Mission
9/17/2014© LEWA Process Technologies, Inc. 47
LEWA Process Technologies – Processing Brilliance
LEWA Process Technologies draws on its deep expertise in fluid
dynamics to conceive, construct and install advanced downstream
processing platforms.
Our solutions combine years of research in manipulating the
movement of critical fluids with proven pump technology to deliver
systems with unmatched precision, reproducibility, flexibility and
efficiency.
We help customers in clean industries such as biotechnology and
pharmaceuticals gain competitive advantage by giving them tools to
create the next generation of breakthrough products.
More at www.lewapt.com
Reliable and Safe.
Consistent and Precise.
9/17/2014© LEWA GmbH 48
LEWA Process Technologies systems do
not compromise on process integrity. We
employ our leading sanitary and hygienic
pumps known for exceptional precision
and long life with low maintenance.
Ingenuity coupled with leading pump
technology. That is the no compromise
promise from LEWA Process
Technologies.
Flow Purity.
System Integrity.
9/17/2014© LEWA GmbH, v1.0 49
LEWA Process Technologies systems
are centered on leading sanitary and
hygienic pumps known for exceptional
precision and long life with low
maintenance.
Ingenuity coupled with leading pump
technology. That sets LEWA Process
Technologies apart from others.
Precise. Repeatable.
Formulation Consistency
9/17/2014© LEWA GmbH, v1.0 50
Making your process repeatable and the
quality spot on batch to batch is a
strength of LEWA. We employ our
leading sanitary and hygienic pumps
known for exceptional precision and our
automation package simplifies control
and quality documentation.
Ingenuity coupled with leading pump &
dispensing technology. That is the no
compromise promise from LEWA.