Week of September 29, 2008

24 year old female. ThinPrep papA. LactobacillusB. GonorrheaC. TrichomonasD. Bacterial VaginosisE. Artifact 1

24 year old female. ThinPrep papD. Bacterial Vaginosis –

coccobacilli cover the squamous cells. Also called “Clue cells” 1

2

43 year old male. FNA of neck massA. Nematode wormB. RhabdomyosarcomaC. Normal muscleD. Squamous cell carcinomaE. Colloid

2

43 year old male. FNA of neck massC. Normal muscle – strips/chunks of

muscle with peripherally placed nuclei and striations

3

57 year old male. Urine cytology

A. Reactive urothelial cellsB. High grade TCCC. Low grade TCCD. Squamous cell carcinomaE. Polyoma virus

3

57 year old male. Urine cytologyE. Polyoma virus – enlarged cell with

smudgy intranuclear inclusion. Do not mistake for High grade TCC!

4

62 year old female. Peritoneal fluidA. Positive for tumor - AdenocarcinomaB. Reactive mesothelial cellsC. AtypicalD. Positive for tumor – LymphomaE. Benign lymphocytic effusion

4

62 year old female. Pleural fluidA. Positive for tumor - Adenocarcinoma “Cannonball” group of epithelial cells with

large nuclei and distinct cell borders. Pleomorphism and irregular nuclear membranes are seen. Patient had history of breast cancer.

5

53 year old female. Pleural fluidA. Positive for tumor - AdenocarcinomaB. Reactive mesothelial cellsC. AtypicalD. Positive for tumor – LymphomaE. Benign lymphocytic effusion

5

53 year old female. Pleural fluidA. Positive for tumor – Adenocarcinoma Large pleomorphic single cells with secretory vacuoles c/w adenoca. Signet rings forms are noted. Pt also has history of breast cancer. Don’t miss single malignant cells in effusions!

6

36 year old female. Thyroid FNAA. GoiterB. IndeterminateC. Positive for tumor – papillary

thyroid carcinomaD. Positive for tumor – follicular

carcinomaE. Hurthle cell neoplasm

6

36 year old female. Thyroid FNAB. Indeterminate – multiple

microfollicles with no colloid in the background. This is suspicious for a potential follicular neoplasm. On cytology we call this indeterminate because we cannot determine whether this is a follicular adenoma or a follicular carcinoma (for which you need to see either capsular +/or vascular invasion on histo)

7

60 year old male s/p bilateral lung transplant. BAL

A. AspergillusB. CandidaC. PCPD. MucorE. Fusarium

7

60 year old male s/p bilateral lung transplant. BAL

A. Aspergillus – septated hyphae with 45 degree branching

8

29 year old female. ThinPrep pap

A. ReactiveB. Endocervical cellsC. ASC-USD. LSILE. HSIL

8

29 year old female. ThinPrep pap

D. LSIL – enlarged nuclei with koilocytic change. Also have binucleates

9

63 year old male. FNA of lungA. AdenocarcinomaB. Squamous cell carcinomaC. Small cell carcinomaD. BACE. Reactive lymphocytes

9

63 year old male. FNA of lungC. Small cell carcinoma – note the

molding

10

26 year old female. ThinPrep papA. LSILB. HSILC. Endometrial cellsD. Squamous cell carcinomaE. Tubal metaplasia

10

26 year old female. ThinPrep papB. HSIL