Week 4 Lecture Outlinhe
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Transcript of Week 4 Lecture Outlinhe
Vital Signs: Body Temperature
Video 4.1: Introduction to Thermoregulation
- metabolic rate: measure of all of the chemical reactions going on in the body at a given time
o certain organs have continuous rate of metabolism that contributes significantly to establishing our resting metabolic rate --e.g., the heart, brain, liver, kidneys
o body core –the internal region of body where we normally maintain a fairly constant temperature
o heat is released with an increase in metabolic rate because cells are not 100% efficient –increased metabolism, as occurs during exercise, creates more heat
o core body temperature-
normal range: 35.8°C-38.2°C
normal core temperatures vary between individuals and throughout the day
lowest during-
highest during-
important to maintain a normal temperature for optimal enzyme activity-
o body shell
more temperature fluctuation occurs in the body shell based on atmospheric temperature and body’s metabolic
rate
blood – mechanism of heat transfer in body
picks up heat in body core > carries heat to less metabolically active parts of body
- types of heat transfer:o conduction –heat transfer between 2 objects in direct content
o radiation –transfer of heat in the form of infrared waves
o convection –heat loss that occurs because a warm fluid (which could be air or liquid) rises away from the body surface and is replaced by a cooler fluid
body heat will transfer to the cold fluid, which will then rise away from the body surface and be replaced by cooler fluid
the cooler fluid will warm (due to heat transfer from the body) –and then it will rise away from the body surface
the greater the temperature gradient between the body and the cool fluid that replaces the warm fluid, the greater will be the heat loss
wind chill
o evaporation heat is required to vaporize water (called the “heat of
vaporization”) it is not sweating per se that makes us feel cooler –it is
the evaporation of sweat that cools us when sweat evaporates, it is body heat that vaporizes the
water in sweat
heat index
- heat loss from the body can be sensible or insensible:
o sensible heat loss-
example: sweating
o insensible heat loss-
example: evaporation that occurs as air moves past the airway surfaces during inhalation
Video 4.2: Maintaining Body Temperature
Reflex arc:
- all reflex arcs begin with a sensory receptor –the temperature sensors of the body are called thermoreceptors
o peripheral thermoreceptors
sensitive to hot and cold peripheral thermoreceptors provide the information which helps
us cope with environmental temperature changes
body has high water content which creates thermal inertia –peripheral thermoreceptors make the brain aware of changes in environmental temperature so that adjustments can be made to maintain core temperature
o central thermoreceptors
- neurons carry the sensory input to the hypothalamus, which is the control center for body temperature regulation
o temperature control center is located in the preoptic nucleus of the hypothalamus
- motor effects allow us to maintain our temperature
o temperature homeostasis –state of dynamic equilibrium in which we maintain our body core temperature within the normal range (35.8°C-38.2°C)
o decreased body temperature –when body temperature falls below the hypothalamic set point it causes:
vasoconstriction of subcutaneous blood vessels
shivering- the slight shaking or shuddering that we call “shivering” is
due to rapid involuntary muscle contractions remember: about 60% of the energy stored in the
molecular bonds of fuel molecules is released as heat thus, as skeletal muscles generate ATP to fuel shivering,
they also generate a lot of heat
hormonal secretion in prolonged cold, hormones can stimulate metabolism &
help to maintain a normal body temperature
o increased body temperature – body/blood is warmer than the hypothalamic set point
vasodilation of subcutaneous blood vessels
increases heat loss via radiation (and possibly convection)
sweating
o negative feedback is built into the temperature regulating system
Video 4.3: Hypothermia & Hyperthermia
- hypothermia –condition in which the body core temperature falls below the normal range
o normal physiological mechanisms to warm body (constriction of subcutaneous blood vessels, shivering) are not enough to raise body temperature back to the normal range
o manifestations - decreased heart rate decreased respiration rate decreased blood pressure brain functions will also begin to fail if the hypothermia become
severe enough and/or prolonged
o interventions -
- hyperthermia:
o varies in severity
heat exhaustion
blood cannot circulate effectively due to blood volume loss from excessive sweating
conflicting signals
can occur after prolonged exercise in heat
manifestations
interventions:
heat stroke –condition is more severe than heat exhaustion
positive feedback cycle created that generates heat loss mechanisms that worsen the condition
manifestations: o hot, dry skin
o organs shut down (i.e., organ failure)
predisposing factors can put some people at higher risk :o older adults
o young children and neonates
o people with cardiovascular disease-
o pregnant women-
o people who have impaired fluid regulation capability (as in chronic kidney failure)-
interventions :
Video 4.4: Fever
- Fever:
o pyrogens –molecules released by the cells of the immune system that have the ability to raise the hypothalamic set point
released by cells of the immune system (mainly) and can circulate in the blood
when they arrive in the brain, they affect hypothalamic function when hypothalamus set point is increased, the higher body
temperature of a fever is interpreted by the hypothalamus as “normal”
o may feel cool despite high temperature
o a fever “breaks” when the pyrogens are removed from body and hypothalamus returns to normal set point
o fever is not always a bad thing
Video 4.5: Assessing Body Temperature Demo
- Types of thermometers-
o oral
place probe of thermometer in sublingual pocket-
close to sublingual artery – a deep artery, which gives a more accurate measure of core body temperature
o temporal
run probe over patient’s forehead –assesses temperature in temporal artery, which also carries blood a short distance from the core and gives a relatively accurate measure of core temperature
o tympanic
placed in external auditory canal against tympanic membrane (or ear drum)
close to hypothalamus --thus, gives a fairly accurate measure of core temperature
o axillary
measured in axilla (or armpit) it is difficult to get an accurate reading at this site, for
various reasons
o rectal
sensor probe is placed in rectum requires practice and training for accurate readings
- important to take a temperature when patient is healthy –then, are able to compare future readings to this baseline temperature