We know how it works. - · PDF fileGeneral Information. Page 4 / 20. Analytics and Application...

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Service catalogue2018
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4 - 7 Analytics and Application Testing
8 - 10 Biological Product Testing
11 - 14 Product Development
15 - 17 Insect Breeding
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General Information
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Analytics and Application TestingOur service portfolio for product analysis and application testing
The analytical services of BioGenius can be performed according to the OECD GLP guidelines as well as under NON GLP conditions.Therefore BioGenius is capable of supporting its customers with data packages for any product authorization according to the following international regulations e.g:
Biocidal Products Regulation 528 / 2012 AVPMA and US EPA Plant Protection Products Regulation 1107 / 2009 EC 440 / 2008 (REACH)
as well as further international product authorization requirements.
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Analytical Data Packages
Description Methods
1. Analytical method development for active ingredients and products
Insecticides and repellents Rodenticides Wood preservation Disinfectants, hygiene, preservatives Water treatment, metal working fluid
2. Validation of analytical methods for product authorization
GC FID/MS, HPLC-DAD/MS, IC, titration, UV-VIS photometry
SANCO 3030 / 99
4. Shelf life studies for product authorization and preliminaryscreening tests
Accelerated stability of product and packaging e.g.:
- 0 C, 54 C, 40 C, 35 C, 30 C
Real time stability of product and packaging e.g. Stability against metals and ions according to OPPTS 830.6113
The studies can be combined with all necessary application parameters which are required for the product authorization
CIPAC MT 39.3CIPAC MT 46.3
5. Determination of content for active substances, impurities and by-products
PT 18 and 19 Insecticides and repellents PT 14 Rodenticides PT 8 Wood preservation PT 1 - 6 Disinfectants, hygiene, preservatives PT 11 and 13 Water treatment, metal working fluid
Other product types on request.
3. 5-Batch analyses of actives, active isomers, co-formulants and impurities in accordance to BPR and PPP
Method development Method transfer Method validation 5-Batch analysis
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Description Methods
6. Physical / chemical properties for product authorization
6.1 Spray Application
Intermediate appearance, colour, odour Packaging appearance Weight loss Particle size distribution using Malvern Spraytec laser evaluation Density of intermediate / propellant mix. Spray and stream character (picture, diameter, etc.) Total discharge / residue after use Discharge rate Valve clogging Can pressure (20 C and 50 C) Flame length and ignition distance of spray cans Drum test (space ignition of spray cans)
CIPAC MT 187A.03 / FEA 605FEA 644WHO / FAOFEA 643WHO / FAOFEA 604 / 606UNUN
6.2 Liquid Application
Formulation appearance, colour, odour Packaging appearance Weight loss Corrosion testing Viscosity Rel. density pH-value Acidity / alkalinity Refractive index Surface tension Particle size distribution for powders using Malvern spraytec laser evaluation Persistent foaming Suspensibility Dispersion stability Dilution stability Emulsion stability Pourability of suspension concentrates Water content (Karl-Fischer) Wet sieving Spontaneity of dispersion
DIN 50905-1 / ASTM G31-72OECD 114 / CIPAC MT 192 / MT 22.1EC A.3 + OECD 109CIPAC MT 75.3CIPAC MT 191
EC A.5CIPAC MT 187CIPAC MT 47.3 + 47.2CIPAC MT 184CIPAC MT 180CIPAC MT 41.1 + 41CIPAC MT 36.3CIPAC MT 148 +148.1CIPAC MT 30.5CIPAC MT 185CIPAC MT 160
6.3 Solid Application (granular, tablet, paste, block, etc.)
Formulation appearance, colour, odour Packaging appearance Weight loss Particle size distribution for powders using Malvern spraytec laser evaluation Bulk density Wettability Suspensibility Sieve analysis, dry sieving Attrition resistance Attrition of tablets Flowability Dustiness Water content (Karl-Fischer) Disintegration time for tablets Dissolution rate of water soluble bags Wet sieving Loss on drying Spontaneity of dispersion of water dispersible granules Degree of dissolution and dilution stability
CIPAC MT 187CIPAC MT 186CIPAC MT 53.3CIPAC MT 184CIPAC MT 170CIPAC MT 178 + 178.2CIPAC MT 193CIPAC MT 172CIPAC MT 171CIPAC MT 30.5WHO / M / 28CIPAC MT 176CIPAC MT 185CIPAC MT 17.4CIPAC MT 174CIPAC MT 179
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6.3 pH-value Acidity Persistent foaming Tablet integrity
MT 75.3MT 19.1MT 47.2 + 47.3WHO / M / 27
6.4 Safety data packages for product authorization
In-house Melting point Boiling point Rel. density Surface tension Flash point Flammability solid, screening or complete test Oxidising properties for solids
External Vapour pressure Water solubility flask method or column elution method Flammability gases, screening or complete test Flammability contact with water Pyrophoric properties Explosive properties Auto ignition temperature (liquids and gases) Rel. self ignition temperature for solids Oxidising properties liquids Flash point Flammability solid, screening or complete test Oxidising properties for solids
EC 440 / 2008
EC A.1EC A.2EC A.3EC A.5EC A.9EC A.10EC A.17
EC A.4EC A.6EC A.11EC A.12 / UN N.5EC A.13 / UN N.2 / N.3EC A.14 / UN 1 (c), 2 (c), C.1EC A.15EC A.16 / UN N.4EC A.21 / UN O.2UN L.2UN N.1UN O.1;O.3
7. Specific studies and application testing
Corrosivity testing analogue UN test C.18 DIN 50.905 part 4 Evaporation properties of vaporizer products Residue of active ingredients in vaporizer products after use Product treatment properties during use Stain tests to determine colour or liquid stains on fabrics or other surfaces
Gravimetrical or in-house analytical methods
In-house method
8. Determination of active ingredient concentration in spaces
Concentration of active ingredients during usage time
Determination of max. concentration and degradation of active ingredients during use
Determination of active ingredient and residues on surfaces during use
In accordance with data requirements for product exposure scenarios and product risk assessments
Non GLP
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Description Methods
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The efficacy test services of BioGenius can be performed analogous to GLP.Therefore BioGenius is capable of supporting its customers with data packages for product screening as well as for product authorization according to the following international regulations:
Guidance on the Biocidal Products Regulation according to BPR 528 / 2012 WHO guidelines
and further international product authorization requirements.
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Biological Product TestingOur service portfolio for efficacy testing of insecticide and repellent products
General Information

Target Description Methods
1. Cockroaches - Direct spray treatment- Residual effect on surfaces- Cockroach bait testing- Flushing effect- Egg stopper effect- Attractiveness and repellent effect- Secondary kill (Domino effect)- Space effect- Repellent effect
Laboratory test (screening)Simulated-use testField test
2. Ants - Direct spray treatment- Residual effect on surfaces- Ant bait tests against workers (kill)- Ant bait tests (colony kill)- Attractiveness- Repellent and space (repellent) effect
3. Termites - Residual effect on surfaces- Direct spray treatment
Laboratory test (screening)
4. Bed bugs - Residual effect on surfaces- Direct spray treatment- Space effect- Tests with treated fabric
Laboratory test (screening)Simulated-use test
5. Ticks - Tests for skin repellent- Tests with treated fabric- Residual effect on surfaces- Direct spray treatment- Space effect
6. Mites - Efficacy against house dust mites- Residual effect against mites- Repellent effect against mites- Direct spray treatment red poultry mites- Space effect red poultry mites
7. Fleas - Direct spray treatment- Residual effect on surfaces- Larvicidal effect- Space effect
New
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Target Description Method
Test rooms
9. Textile attacking insects
- Moth product testing in cabinets / drawers- Repellent effect on clothes moths- Test of traps- Larvicidal effect against clothes moth- Larvicidal effect against carpet bettles- Carpet beetle tests in cabinets / drawers- Textile damage (according woolmark method)- Space effect
Laboratory test (screening)Simulated-use testISO 3998
10. Stored goods-attacking insects
- Test of glue/pheromone traps- Direct spray treatment- Larvicidal effect- Space effect
11. Flies - Aerosol tests- Residual effect on surfaces/in rooms- Efficacy of fly catcher/window sticker- Arm in cage test / space repellent effect- Larvicidal effect- Attractivness of baits- Bait tests
12. Mosquitoes - Aerosol tests- Residual effect on surfaces/in rooms- Arm in cage tests for skin repellent- Arm in cage tests using treated fabrics- Efficacy of bed nets against mosq

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