Water soluble vitamins biotin ppt Lecture 4 BIOCHEMISTRY [email protected]
-
Upload
vijaya-marakala -
Category
Health & Medicine
-
view
1.142 -
download
15
Transcript of Water soluble vitamins biotin ppt Lecture 4 BIOCHEMISTRY [email protected]
![Page 1: Water soluble vitamins biotin ppt Lecture 4 BIOCHEMISTRY vkunder637@gmail.com](https://reader033.fdocuments.us/reader033/viewer/2022052121/554e92a2b4c90573338b4ec9/html5/thumbnails/1.jpg)
WATER SOLUBLE VITAMINS
Dr Vijay Marakala MBBS.,MD.Assistant professor
BiochemistrySIMS&RC
![Page 2: Water soluble vitamins biotin ppt Lecture 4 BIOCHEMISTRY vkunder637@gmail.com](https://reader033.fdocuments.us/reader033/viewer/2022052121/554e92a2b4c90573338b4ec9/html5/thumbnails/2.jpg)
WATER SOLUBLE VITAMINS
BIOTIN
![Page 3: Water soluble vitamins biotin ppt Lecture 4 BIOCHEMISTRY vkunder637@gmail.com](https://reader033.fdocuments.us/reader033/viewer/2022052121/554e92a2b4c90573338b4ec9/html5/thumbnails/3.jpg)
BIOTIN - CHEMISTRY
Imidazole ring
Thiophene ring Valeric acid
![Page 4: Water soluble vitamins biotin ppt Lecture 4 BIOCHEMISTRY vkunder637@gmail.com](https://reader033.fdocuments.us/reader033/viewer/2022052121/554e92a2b4c90573338b4ec9/html5/thumbnails/4.jpg)
BIOTIN - SOURCES
It is widely distributed in
the foods
Liver, kidney, vegetables and
egg yolk are important
source
Biotin also synthesized by
intestinal bacteria
![Page 5: Water soluble vitamins biotin ppt Lecture 4 BIOCHEMISTRY vkunder637@gmail.com](https://reader033.fdocuments.us/reader033/viewer/2022052121/554e92a2b4c90573338b4ec9/html5/thumbnails/5.jpg)
BIOTIN - RDA
RDA 20=30µg/day
![Page 6: Water soluble vitamins biotin ppt Lecture 4 BIOCHEMISTRY vkunder637@gmail.com](https://reader033.fdocuments.us/reader033/viewer/2022052121/554e92a2b4c90573338b4ec9/html5/thumbnails/6.jpg)
BIOTIN - ABSORPTION
It is absorbed in the small
intestine and reaches liver
and other tissues through
circulation
![Page 7: Water soluble vitamins biotin ppt Lecture 4 BIOCHEMISTRY vkunder637@gmail.com](https://reader033.fdocuments.us/reader033/viewer/2022052121/554e92a2b4c90573338b4ec9/html5/thumbnails/7.jpg)
BIOTIN - FUNCTIONS
Biotin is a coenzyme of carboxylase
reactions
4 enzymes in the body require
biotin
![Page 8: Water soluble vitamins biotin ppt Lecture 4 BIOCHEMISTRY vkunder637@gmail.com](https://reader033.fdocuments.us/reader033/viewer/2022052121/554e92a2b4c90573338b4ec9/html5/thumbnails/8.jpg)
BIOTIN - FUNCTIONS
Acetyl CoA carboxylase
Propionyl CoA carboxylase
Pyruvate carboxylase
β Methyl crotonyl CoA carboxylase
BIOTIN
![Page 9: Water soluble vitamins biotin ppt Lecture 4 BIOCHEMISTRY vkunder637@gmail.com](https://reader033.fdocuments.us/reader033/viewer/2022052121/554e92a2b4c90573338b4ec9/html5/thumbnails/9.jpg)
![Page 10: Water soluble vitamins biotin ppt Lecture 4 BIOCHEMISTRY vkunder637@gmail.com](https://reader033.fdocuments.us/reader033/viewer/2022052121/554e92a2b4c90573338b4ec9/html5/thumbnails/10.jpg)
![Page 11: Water soluble vitamins biotin ppt Lecture 4 BIOCHEMISTRY vkunder637@gmail.com](https://reader033.fdocuments.us/reader033/viewer/2022052121/554e92a2b4c90573338b4ec9/html5/thumbnails/11.jpg)
![Page 12: Water soluble vitamins biotin ppt Lecture 4 BIOCHEMISTRY vkunder637@gmail.com](https://reader033.fdocuments.us/reader033/viewer/2022052121/554e92a2b4c90573338b4ec9/html5/thumbnails/12.jpg)
BIOTIN DEFICIENCY
Biotin deficiency is rare in humans because it is present in most of the common foods.
However experimentally induced biotin deficiency symptoms in man are dermatitis, alopecia, depression, muscular pain and anemia
![Page 13: Water soluble vitamins biotin ppt Lecture 4 BIOCHEMISTRY vkunder637@gmail.com](https://reader033.fdocuments.us/reader033/viewer/2022052121/554e92a2b4c90573338b4ec9/html5/thumbnails/13.jpg)
BIOTIN - ANTAGONISTS
AVIDIN
![Page 14: Water soluble vitamins biotin ppt Lecture 4 BIOCHEMISTRY vkunder637@gmail.com](https://reader033.fdocuments.us/reader033/viewer/2022052121/554e92a2b4c90573338b4ec9/html5/thumbnails/14.jpg)