Warm-up: 1.When you are finished with your quiz, pick up a “Pedigree Analysis” guideline from...
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Transcript of Warm-up: 1.When you are finished with your quiz, pick up a “Pedigree Analysis” guideline from...
Warm-up:
1. When you are finished with your quiz, pick up a “Pedigree Analysis” guideline from the front of the classroom. You can use this paper to write down your notes on Pedigree Charts.
Read the “Biology Update: Huntington Disease” on page 192 of your text book.
2.
Overview
I. What is a pedigree? A. Definition
B. Uses
II. Constructing a pedigree A. Symbols
B. Connecting the symbols
C. Example
III. Interpreting a pedigree
A Pedigree is…
GenerallyGenerally: A genetic family tree: A genetic family tree
SpecificallySpecifically: It is a chart of the : It is a chart of the genetic history of family over several genetic history of family over several generations.generations.
Back to Overview
A Pedigree is used to…
• Diagnose the likelihood of a Diagnose the likelihood of a disease or trait.disease or trait.
• Scientists or a genetic counselor Scientists or a genetic counselor would find out about your family would find out about your family history and make this chart to history and make this chart to analyze.analyze.
Back to Overview
Connecting Pedigree Symbols
• Married couples
• Siblings
Examples of connected symbols:Examples of connected symbols:
Connecting Pedigree Symbols
• Fraternal twins
• Identical twins
Examples of connected symbols:Examples of connected symbols:
Back to Overview
Interpreting a Pedigree Chart
1. Determine if the pedigree chart shows an autosomal or X-linked disease.
a. If most of the males in the pedigree are affected the disorder is .
b. If it is a 50/50 ratio between men and women the disorder is .
X-linked
autosomal
Interpreting a Pedigree Chart
2. Determine whether the disorder is dominant or recessive.
a. If the disorder is dominant, one of the parents must have the disorder.
b. If the disorder is recessive, neither parent has to have the disorder because they can be heterozygous.