Warfarin underused in elderly women with AF

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Inpharma 1294 - 30 Jun 2001 Warfarin underused in elderly women with AF Elderly women with atrial fibrillation (AF) are less likely to receive warfarin than elderly men, report researchers from Canada. Their 3-year study included data for 773 patients with newly diagnosed AF enrolled in the Canadian Registry of AF (CARAF). * The overall use of antithrombotic agents, or of other cardiac medications, did not differ significantly by gender. However, among patients aged 75 years with 1 stroke risk factor, women were significantly less likely to receive warfarin than men (24.5 vs 44.9%). On the other hand, women aged 75 years were twice as likely to receive aspirin, compared with men of that age group. The analysis also showed that women receiving warfarin were 3.35 times more likely to experience a major bleed than men receiving warfarin. * This study was supported by Procter and Gamble Pharmaceutical Canada, Inc. CARAF received support from Knoll Pharmaceuticals and DuPont Pharma. Humphries KH, et al. New-onset atrial fibrillation: sex differences in presentation, treatment, and outcome. Circulation 103: 2365-2370, 15 May 2001 800867957 1 Inpharma 30 Jun 2001 No. 1294 1173-8324/10/1294-0001/$14.95 Adis © 2010 Springer International Publishing AG. All rights reserved

Transcript of Warfarin underused in elderly women with AF

Inpharma 1294 - 30 Jun 2001

Warfarin underused in elderlywomen with AF

Elderly women with atrial fibrillation (AF) are lesslikely to receive warfarin than elderly men, reportresearchers from Canada.

Their 3-year study included data for 773 patients withnewly diagnosed AF enrolled in the Canadian Registry ofAF (CARAF).* The overall use of antithrombotic agents,or of other cardiac medications, did not differsignificantly by gender. However, among patients aged≥ 75 years with ≥ 1 stroke risk factor, women weresignificantly less likely to receive warfarin than men(24.5 vs 44.9%). On the other hand, women aged ≥ 75years were twice as likely to receive aspirin, comparedwith men of that age group. The analysis also showedthat women receiving warfarin were 3.35 times morelikely to experience a major bleed than men receivingwarfarin.* This study was supported by Procter and Gamble PharmaceuticalCanada, Inc. CARAF received support from Knoll Pharmaceuticals andDuPont Pharma.

Humphries KH, et al. New-onset atrial fibrillation: sex differences in presentation,treatment, and outcome. Circulation 103: 2365-2370, 15 May 2001 800867957

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Inpharma 30 Jun 2001 No. 12941173-8324/10/1294-0001/$14.95 Adis © 2010 Springer International Publishing AG. All rights reserved