Family (genome ) genus Diseases (viruses)

Arteriviridae:Spherical virus, icosahedral nucleocapsid, 1 nucleocapsid protein, 6 envelope peotein: E, GP1,GP2, GP3, GP4, M, Genome: linear SS+ive sense RNA

Imp viruses: 1. Equine viral arteritis virus2. Porcine respiratory and reproductive syndrome virus3. Simian hemorrhagic fever virus4. Lactate dehydrogenase alleviating virus:

Reo viridae: Respiratory enteric orphan, segmented genome ds.DNA, non-eneloped, ecosahedral symmetry, and 10-12 segments, 8 structural proteins

Orthoreo virus, Rota virus, Coltivirus, Aquavirus, Orbi virus In mammals).

Oryza virus, Phytoreovirus, Cypo virus, FigivirusIn insect, plants,

Orthoreovirus: 2 types of viruses 1) Mammalian orthoreovirus2) AvianGenus Orbi virus(arbo V): 10 segments. 5 imp viruses blue tongue virus, African horse sickness virus, Epizootic Hemorrhagic disease virus, Palyan virus, Equine encephalosis virus

G:Rota virus:11 segment of genome. Diarrhea, enteritis,Genus Coltivirus: 12 segments of genome. And the virus in it is Colorado ticks fever virus.G:Aquaeovirus: 11 segments. effect aquatic. Cause necrosis in the parenchymal organs.

Birna viridar:Non- enveloped, icosahedral symmetry, size of virus is 6o nm.Genome: ds RNA, 2 segment of RNA, A & B, naked,

Avibirna (affect poultry birds) infectious bursal disease virus (gumboro)

Aqua birna ( fish mostly) infectious pancreatic necrosis virus

Enteromobirna ( insects and arthropods)

Poxviridae:

skin infection mostly.Pleomorphic but roughly brick shape some time ovoid shape.Size: largest. 220-450 nm long, width= 140-260 nm. Enveloped, resist dry heat,Genome: ds.DNA up to 130 Kb. encode for 150-300 proteins, replicate in cytoplasm.It contain 2 subfamilies1. Chordopoxviridae (humans & animals)2. Entomo poxviridae (insects)

Orthopoxvirus: vaccinia virus,Cow pox,Buffalo pox, Rabbit pox, Camel pox, Monkey pox, Horse pox,Small pox (Small pox is caused by the variola)

Genus Parapox virus: Bovine popular stomatitis virus, ORF ( contagious ecthyma virus), Pseudocow pox: Cause milk diseases

Genus avipox virus: affect avian spies.

Fowl pox, turkey pox, quail pox, pigeons pox, sparrow pox, starling pox, juno-pox(peacock).

Genus capripox: Sheep pox virus, goat pox virus, lumpy skin disease virus (neethling virus)

Laprovirus: Myxoma (callifornia myoxma virus), Rabit fibroma, Squirrel fibroma

Genus suipox virus: swine pox virus

Genus mollusci pox virus: molluscom contaigosum (humans)

Yata pox virus: yaba monkey tumous virus

Adenoviridae:

very host sp non-enveloped, icosahedron, nucleocapsid: is 70-90nm. Capsomere:252, fiber along with pentons contain type specific antigens. On the basic of this classification of virus isdone. Genome: 26-45 Kb And it is ds DNA. 40 protein

Mast adenovirus Human adenovirus 6 types A-F, Bovine adenovirus types1-type 10 Canine adenovirus (2 types 1-2) Type 1 disease: infectious canine hepatitis, Type 2: respiratory infection.Equine adenovirus (2 type (1-2 ) respiratory infection, Ovine adenovirus (6 types (1-6) 6) Porcine adenovirus: (type 1-4) Deer adenovirus: cause systemic vasculitis with hemorrhage and pulmonary oedema, Ave adenovirus: it has chicken adenovirus, thy cause respiratory, enteric diseases,

Avi adenovirus. (Group 1) a) contain fowl adenovirus, 5 types (A, B, C, ,D, E,),inclusion bodies hepatitis virus, chicken embryo lethal virus, quail bronchitis virus,Chicken adenovirus: cause respiratory diseases.

Ata adenovirus. (Group 3) egg drop syndrome,

Si adenovirus. (Group 2) turkey hemorrhagic enteritis virus,Marble spleen disease virus of pheasant.HPS(hydropericaridial syndrome) virus of chicken

Toga-viridae:Toga- Latin word means gown, cloak, envelop is like gownspherical, enveloped 50-70nm. Nucleocapsid: icosahedral 40 nm Genome: linear SS+ive sense RNA. Envelop: has 2 viral glycoprotein E1 andE2 ,somevirus have also E3. NSP: NSP1, NSP2, NSP3, and NSP4.

α virus : (arbo virus)Robi virus

1. (EEE) Eastern equine encephalitis2. (WEE) Western equine encephalitis in equines3. (VEE) venegulean equine encephalitis

Getah virus:

Bunyaviridae:(Arbovirus). ntroduction: it contain 350 viruses .there is place in uganda called bunyamwera.Genome: –ive sense SS RNA virus. helical symmetry and enveloped and size upto 100nm. segmented genome and a (S, M, L)replication in cytoplasm.

Bunya virus akaban virus ( akaban disease)in sheep and cattle Microencephaly: it slows down the mitosis stage. It also caused abortion

Nair virus narobi sheep disease: causes haemorrhagic enteritisPhlebo virus reef velley fever: abortion and hepatitis main featureTospo virus ( humans)hanta virus (humans)

Flaviviridae:Latin word means flavors, spherical shape, envelop virus. Genome: linear SS +ive sense RNA.2 envelop proteins: E & M. single nucleocapsid protein.

Flavi virus: contain arbo virus 2 types

A. Tick bornB. Mosquito

Tick born encephalitis group: 2 imp virus, Louping ill virus ( in sheep), Pouassam (in horses). Mosquito born: Japanese encephalitis virus, Marray valley encephalitis virus (infect human and birds), West Nile virus (infect human, horses & birds), Saint Louis encephalitis ( infect human & birds), Wessel born virus ( infect sheep), Yellow fever virus (human). Dengue fever virus (infect human)

Pesti virus: (not arbovirus) 1. Border disease virus (infect sheep)2. BVD ( 1, 2)in cattle

Hepaci virus:

AfarviridaeEnveloped, icosahedral capsid, 170-190 nm. DiameterGenome is single large molecule of dsDNA 170-190 nm. There are more than 50proteins Resistance:.

1 important virus African swine fever virus

Papillomaviridae:Latin word Papilla: nipple(worts):Warts: Benign hyperplastic epithelial proliferation of skin & mucous membrane.Fibripapilloma, papilloma. Highly SP. Specific virus. Contagious in nature very common in horses & cattleResistance: Incubation period is 3-18 months.Warts are from small nodule to large cauliflower.

Only 1 genera papilloma virus. Properties: naked icosahedral capsid. & 55 nm diameter capsid is composed of 72 capsomeres. Genome is single circular molecule of dsDNA it encode for 8-10 proteins. & out of 8-10 proteins 2 are structural proteins L1 & L2 & remainder are enzyme for replication.

Canine papillomavirus Bovine papillomavirus Ovine papilllomavirus Caprine papillomavirus

Pathogenisis: entry occur through the abrasion of the skin. Multiplication occur in nucleus. It has affinity for the epithelial cells. Specially for epithelial Sq. cells of skin and the upper elementary track.These virues are not grown on invitro cell culture. Cell tropism is limited

Polyomaviridae:Non-enveloped virus with capsid ecosahedral symmetry 40nm in diameter. Genome is singlemolecule of circular dsDNA. Genome encode for three structural proteins. , VP1, VP2,VP3 & 5non-structural protein.

1 imp genera: polyomavirus A. Bovine polyomavirusB. Murine polyomavirusC. SV 40polyomavirus ( monkey virus)More important in human than animals.

Hepadnaviridae:Properties: enveloped, icosahedral symmetry, nucleocapsid, genome is dsDNA sometime ssDNA.There DNA polymerase act as reverse transcriptase.

2 genusa) Orthohepadna virus (humans) hepatitis B-virus,b) Avihepadnavirus (duck) duck hepatitis B-virus

Replication is unique: of virus is important.i. Symmetric DNA is converted to closed circular DNA.ii. Transcription of circular DNA in host cell to generate mRNAiii. These RNA are then converted to into –ive DNA (reverse transcriptase)iv. There will be formation of DNA complementary strandThere are 4 important proteins 2 surface protein and 2 core protein

Retroviridaeenveloped viruses. ssRNA viruses & replicate through DNA intermediate using RNA dependent DNA polymerase

(reverse transcriptase).oncogenic

Orthoretrovirinae:It include following genera

a) Alpha retrovirus

Avian sarcoma virus Avian leukosis virus Avian erythroblastosis Avian myloblastosis

b) Beta retrovirus Mouse mammary tumor virus Ovine pulmonary adenocarcinoma virus

c) Gamma retrovirus Feline leukemia virus Murine leukemia virus Feline sarcoma virus Murine sarcoma virus Avian reticuloendotheliosis virus

d) Delta retrovirus Bovine leukemia virus Human T-lymphotrophic virus type 1&2

e) Epsilon retrovirus Fish tumor virus

Lentivirinae:sub fam Lentivirus: it include

HIV, BIV, FIV Equine infectious anemia virus

Spumavirinae Spuma virus Huma spumavirus Bovine syncital virus Feline syncital virus