Vice-Presidents of Research Webex Meeting November 25, 2014.

Vice-Presidents of Research Webex Meeting November 25, 2014

Agenda 11:00 11:101. Opening Remarks 11:10 11:302. Reforms Update 11:30 11:403. Transitional Open Operating Grant Program 11:40 11:504. Institute Model Review 11:50 12:055. Strategy for Patient-Oriented Research (SPOR) 12:05 12:156. Engagement with Healthcare Organizations 12:15 12:307. Varia 2

1. Opening Remarks 3

Objective The objective of todays meeting is to: Provide an update on key CIHR initiatives Have a discussion on engagement with healthcare organizations Identify future agenda items 4

2. Reforms Update 5

Reforms Update: Foundation Scheme Applications 1375 applications received at stage 1: 9 applications withdrawn 1366 applications were peer reviewed Breakdown by category: 537 currently funded by CIHR 557 new/early career investigators 272 never held CIHR funds Approximate breakdown by health research pillar: 54% Biomedical 21% Clinical 14% Population Health 11% Health Systems 6

Reforms Update: Foundation Scheme Peer Review The stage 1 review process was recently completed. It included a total of 447 reviewers and 50 Virtual Chair/Moderators. More than 800 applications were discussed using the on-line discussion technology. Identification of reviewers for stage 2 and members for the stage 3 committee is underway. 7

Reforms Update: Foundation Scheme Stage 1 Decisions Stage 1 decisions will be available on December 1, 2014 Institution Paid will receive results for all applicants from their institution as well as aggregate data on the overall competition statistics: Decision (invited/not invited to Stage 2) Standing within the competition Applicants will receive: Decision (invited/not invited to proceed to Stage 2) Standing within the competition All five reviews: o Ratings for each criterion o Written strengths and weaknesses for each criterion 8

Reforms Update: Foundation Scheme Options for Applicants Applicants invited to stage 2 will have one of the following options: 1)Submit a stage 2 Foundation application Application deadline February 5, 2015 2)Submit application to the Transitional OOGP Registration deadline January 9, 2015 Applicants not invited to stage 2 will have the following options: 1) Submit application to the Transitional OOGP 2) Submit application to 2015 Foundation pilot competition 9

Reforms Update: Foundation Scheme Budget Request For the budget request at stage 2, applicants will be required to: Outline their budget request to support the proposed research program. Provide justification for the appropriateness of the funds requested to support the proposed research program. Provide an overview of their funding history and/or any other sources of funding as appropriate. More information on the budget requirements will be available in the coming weeks, including detailed instructions and a set of Qs and As. We are asking that institutions and organizations help us ensure that applicants submit realistic and well-justified budget requests. CIHR expects to fund 120-250 Foundation grants, depending on the budgets requested and funds available. 10

Reforms Update College of Reviewers CIHR will begin to enroll College members in early 2015, in a phased-in approach. The first waves will be CIHRs current and recently active reviewers. The current and recent reviewers who are invited for Foundation Scheme and the Transitional OOGP will be sent College invitations in the coming months. In parallel, a number of targeted recruitment approaches will be developed to address areas where there are gaps in reviewer expertise. Key stakeholders, including research hospitals, will be engaged in the coming months as we begin developing key elements of the College (e.g., targeted and nominated recruitment strategies, recognition/incentive approaches). 11

Reforms Update Project Scheme The Project Scheme design is being tested through a number of pilots. Applicants, research administrators and reviewers are being surveyed throughout the pilots. Pilot results are encouraging so far. Feedback is being incorporated into future pilots as we continue to refine the design. The funding opportunity for the first Project Scheme competition is being developed. It will be posted early in the new year to provide the community with time to prepare. Applications will be due in March 2016. 12

Reforms Update Sunsetting of Legacy Open Programs We are beginning to phase out our current Open programs as we implement the new funding schemes, as outlined in our transition plan. The Transitional OOGP will be the last OOGP competition as we transition to the Foundation Scheme. As we implement the Project Scheme, CIHRs other Open programs will also be sunsetted. The specific sunsetting plan is still under discussion. You will see notices posted in funding opportunities and other formal communications as soon as details are available. 13

3. Transitional OOGP

Transitional OOGP Last OOGP competition as we transition to the new Foundation and Project Schemes A high application pressure is expected since there is no Fall 2014 competition: Fall 2013: 2527 applications; Spring 2014: 2862 applications Transitional OOGP: expecting 3000-3500+ applications; fund 450-600 grants Reminder: Registration deadline is a month earlier than usual (January 9, 2015) to give time to prepare for peer review Application deadline March 2, 2015 Extended peer review period from May 4 to June 25 CIHR will replace the CIHR Academic CV with a modified version of the Biosketch CV for all applicants within the Transitional OOGP. More information will follow later this week through CIHRs Funding News e-newsletter. 15

4. Institute Model Review

5. Strategy for Patient-Oriented Research (SPOR) 17

Canadas Strategy for Patient- Oriented Research (SPOR) An Overview and Update VPR meeting November 25, 2014 Nancy Mason MacLellan Manager, Major Initiatives,CIHR

19 BACKGROUND ISSUE: While Canada is recognized internationally as a leader in health research, evidence shows that this does not always translate into improved health outcomes, enhanced patient experience or innovations in our health care system. MAJOR BARRIER: Research is often too far removed from the health care system, from clinicians, policy-makers, patients, and other key stakeholders. SOLUTION: The Strategy for Patient-Oriented Research - a coalition of federal, provincial and territorial partners, including researchers, patients, provincial health authorities, academic health centres, charities, and the pharmaceutical sector, working together to generate and translate high quality, relevant research into practice. Patient-oriented research aims to ensure that the right patient receives the right intervention at the right time

PRINCIPLES 20 Patients need to be involved in all aspects of the research to ensure questions and results are relevant and integrated into practice Decision-makers and clinicians need to be involved throughout the entire research process to ensure integration into policy and practice Funding under SPOR is based on a 1:1 matching formula with non- federal government partners to ensure relevance and applicability Effective patient-oriented research requires a multi-disciplinary approach SPOR is focused on first-in-human (and beyond) research designed to be transformative in nature and improve patient outcomes and/or the effectiveness and efficiency of the health care system SPOR is outcome driven and incorporates performance measurement and evaluation as integral components of the initiative

CORE ELEMENTS 21 Support for People and Patient-Oriented Research and Trials (SUPPORT) Units SPOR Networks Capacity development Improving the clinical trials environment Patient engagement

SUPPORT UNITS 22 SPOR SUPPORT Units: provincial/territorial/regional centres providing support and expertise to those engaged in patient-oriented research Collective Priorities Data Platforms & Services Methods Support & Development Health Systems, KT & Implementation Real World Clinical Trials Career Development in Methods & HSR Consultation & Research Services

SUPPORT Units Status Update 23 Alberta, Manitoba, Ontario, Quebec, Maritimes (PEI, NB, NS), and Newfoundland & Labrador are at varying stages of implementation British Columbia has submitted a plan and is in the iterative review process. Saskatchewans plan is expected in winter 2015 NWT received seed funding toward the development of a business plan Dialogue continues with Nunavut and Yukon to develop an appropriate way for them to intersect with SPOR The SPOR SUPPORT Unit Council has been established to link representatives from across the SUPPORT Units

NETWORKS 24 National collaborations of patients, health professionals, decision makers, health researchers and other stakeholders to generate evidence and innovations designed to improve patient health and health care systems

Networks Status Update 25 Transformational Research in Adolescent Mental Health: is co-funded by the Graham Boeckh Foundation (GBF). The Network will use TRAM funds, participant resources and leveraged investments in ways most likely to improve the mental health outcomes of 11-25 year olds over the next five years. Primary and Integrated Health Care Innovations: includes targeting individuals with complex needs across their life course; showing capacity to evolve the networks scope over time to include age groups from children to older adults; and proposes multi-sector integration of upstream prevention strategies and care delivery models. Networks in Chronic Disease: CIHR led a consultation to inform decisions of the National Steering Committee regarding the next network opportunities to be launched; the development of an opportunity for networks in chronic disease, through an open competition process was recommended by the National Steering Committee. UPDATE: On June 13, 2014, CIHR and GBF formally announced the launch of ACCESS Canada, the successful TRAM Network in Youth and Adolescent Mental Health, led by Dr. Ashok Malla. UPDATE: Network is being implemented using a phased approach. Member networks are currently working on their applications to become official members of the pan-Canadian Network. UPDATE: A multi-phase funding opportunity for SPOR Networks in Chronic Disease was launched in October 2014.

DEVELOPING CAPACITY 26 To grow, support and sustain a collaborative, interdisciplinary and innovative patient-oriented research environment capable of addressing evolving health care questions, contributing to enhancing patients health care experience and improving health outcomes.

CLINICAL TRIALS ENVIRONMENT 27 Through a partnership between CIHR, Canadas Research-Based Pharmaceutical Companies (Rx&D), and HealthCareCAN, the Canadian Clinical Trials Coordinating Centre (CCTCC) was created to: Measure, monitor and market clinical trial performance improvements Leverage existing work on accreditation, harmonization and streamlining ethics reviews and common contracts Develop a database of patient registries and consider national recruitment strategies Attract international investment in clinical trials A 12-member National Advisory Committee has been formed to provide advice to the Executive Committee. The Canadian Clinical Trial Asset Map (CCTAM) has been developed and will officially be launched in early 2015 A Model Clinical Trials Agreement has been developed Work on an accreditation system for Canadian Research Ethics Boards continues A Working Group on Patient Registries has been formed STATUS UPDATE

28 PATIENT ENGAGEMENT Occurs when patients meaningfully and actively collaborate in the governance, priority setting, and conduct of research, as well as in summarizing, distributing, sharing, and applying its resulting knowledge Patients Provide input on identifying health research priorities Participate in the design and undertaking of research projects Research is conducted in areas patients value Researchers understand the value of patient involvement and patients understand the value of research Improved patient experience with the health system and health outcomes Patients influence and accelerate decision making and uptake of new practices

Patient Engagement Status Update In response to the SPOR Patient Engagement Framework published in June 2014, the CIHR Citizen and Patient Engagement Implementation Strategy is introducing a number of cross-cutting mechanisms across three core areas. Governance and Decision-Making Capacity BuildingTools and Resources Ensuring that citizen and patient engagement is embedded in CIHR programs/processes Ex. Patient and Citizen Participant Pool; mechanism to capture patients and citizens in the College of Reviewers; an incentives/compensation policy to compensate citizens and patients participating in research Ensuring that resources are available to facilitate the participation of citizens and patients in CIHR programs/processes and POR Ex. Funding opportunities for the research community and knowledge users to form active collaborations whereby citizens and patients are engaged early and often in POR; development of a Citizen and Patient Engagement Community of Practice Ensure tools and resources are available to citizens and patients to help prepare them to effectively contribute to/participate in CIHR programs/processes and POR Ex. Orientation tool for boards and committees; development and roll-out of a curriculum to prepare patients for engagement in research; development of a jargon buster to explain research terms

30 KEY BENEFITS Improved health for Canadians by ensuring that the best research evidence moves into practice, enhancing the health care experience for patients and improving health outcomes for Canadians Economic benefits by optimizing spending on health care systems, reinvesting resources where the evidence shows that these can have greatest impact, and attracting private investments in evaluative research Driving innovation in patient-centred care in areas like e-health, implementation science and clinical practice Linking provinces and territories by providing jurisdictions with opportunities to learn from each other, translating best practices in patient- centred care across Canada, and benefitting all Canadians Reversing the decline in private sector clinical research by creating an environment that makes it easier to pursue clinical research in Canada

DISCUSSION and QUESTIONS?

6. Engagement with Healthcare Organizations 32

Engagement 33 There are a number of opportunities to continue to engage on initiatives of joint interest including: WebEx meetings CIHR cross-Canada visits (January to late spring 2015) Association meetings Discussion: What additional efforts should be considered to support proactive, ongoing engagement?

7. Varia 34

Vice-Presidents of Research Webex Meeting November 25, 2014.

Documents

Transcript of Vice-Presidents of Research Webex Meeting November 25, 2014.