V iewR NA Assay...V V t r w a W i s n S y A M A iewR iewRNA® As ools you can eputation bu e ensure...
Transcript of V iewR NA Assay...V V t r w a W i s n S y A M A iewR iewRNA® As ools you can eputation bu e ensure...
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Cancer research
Cancer type
Gastroin
testinal
Lun
g
Breast
Prostate
Brain
Metastasis
Oth
ers
1. Fisher K. W., et al. AMPK promotes aberrant PGC1β expression to support human colon tumor cell survival. Molecular and Cellular Biology Accepted manuscript posted online 08 September 2015. http://www.ncbi.nlm.nih.gov/pubmed/26351140
2. Miyamoto D. T., et al. RNA-Seq of single prostate CTCs implicates noncanonical Wnt signaling in antiandrogen resistance. Science 349(6254):1351–1356 (2015). http://dx.doi.org/10.1126/science.aab0917
3. Sei Y., et al. A hereditary form of small intestinal carcinoid associated with a germline mutation in inositol polyphosphate multikinase. Gastroenterology 149(1):67–78 (2015). http://www.ncbi.nlm.nih.gov/pubmed/25865046
4. Bledsoe J. R., Difficult diagnostic problems in pancreatobiliary neoplasia. Archives of Pathology & Laboratory Medicine 139(7):848–857 (2015). http://dx.doi.org/10.5858/arpa.2014-0205-RA
5. Javaid S., et al. MAPK7 Regulates EMT Features and Modulates the Generation of CTCs. Molecular Cancer Research 13(5):934–943 (2015). http://dx.doi.org/10.1158/1541-7786.MCR-14-0604
6. Takamoto K., et al. One-step nucleic acid amplification assay for detection of axillary lymph node metastases in breast cancer patients treated with neoadjuvant chemotherapy. Annals of Surgical Oncology First online: 08 July 2015 http://dx.doi.org/10.1245/s10434-015-4693-y
7. Shahid M., et al. Branched chain in situ hybridization for albumin as a marker of hepatocellular differentiation: evaluation of manual and automated in situ hybridization platforms. The American Journal of Surgical Pathology 39(1):25–34 (2015). http://www.ncbi.nlm.nih.gov/pubmed/25353287
8. Moy A. P., et al. Microsatellite instability in gallbladder carcinoma. Virchows Archiv 466(4):393–402 (2015). http://www.ncbi.nlm.nih.gov/pubmed/25680569
9. Freidin M. B., et al. Application of RNA in situ hybridisation for identification of circulating tumour cells. Journal of Clinical Pathology 68(8):669-670 (2015). http://dx.doi.org/10.1136/jclinpath-2015-203112
10. Movahedi A., et al. Orthosiphon stamineus: an Asian tea with substantial anticancer properties. Journal of Nutritional Sciences and Dietetics 1(1):44–52 (2014). http://www.researchgate.net/publication/268279379_Orthosiphon_stamineus_an_Asian_tea_with_substantial_anticancer_properties
11. Mlecnik B., et al. Functional network pipeline reveals genetic determinants associated with in situ lymphocyte proliferation and survival of cancer patients. Science Translational Medicine 6(228):228ra37 (2014). http://dx.doi.org/10.1126/scitranslmed.3007240
3
Cancer type
Gastroin
testinal
Lun
g
Breast
Prostate
Brain
Metastasis
Oth
ers
12. Minami H., et al. Background coloration of squamous epithelium in esophago-pharyngeal squamous cell carcinoma: What causes the color change? PLoS ONE 9(1):e85553 (2014). http://dx.doi.org/10.1371/journal.pone.0085553
13. Liu J., et al. Integrated exome and transcriptome sequencing reveals ZAK isoform usage in gastric cancer. Nature Communications 5:3830 (2014). http://dx.doi.org/10.1038/ncomms4830
14. Dudek H., et al. Knockdown of β-catenin with dicer-substrate siRNAs reduces liver tumor burden in vivo. Molecular Therapy 22(1):92–101 (2014). http://www.ncbi.nlm.nih.gov/pubmed/24089139
15. Choudhry H., et al. Tumor hypoxia induces nuclear paraspeckle formation through HIF-2α dependent transcriptional activation of NEAT1 leading to cancer cell survival. Oncogene 34(34):4482–4490 (2015). http://www.ncbi.nlm.nih.gov/pubmed/25417700
16. Yoshimura H., et al. Simultaneous detection of different RNAs using a novel branched DNA in situ hybridization method. Journal of Nippon Medical School 81(2):62–63 (2014). http://www.ncbi.nlm.nih.gov/pubmed/24805090
17. Wu H., et al. LincRNA-uc002yug.2 involves in alternative splicing of RUNX1 and serves as a predictor for esophageal cancer and prognosis. Oncogene 34(36):4723-4734 (2015). http://www.ncbi.nlm.nih.gov/pubmed/25486427
18. Won K. J., et al. Human Noxin is an anti-apoptotic protein in response to DNA damage of A549 non-small cell lung carcinoma. International Journal of Cancer 134(11):2595–2604 (2014). http://www.ncbi.nlm.nih.gov/pubmed/24214091
19. Sullivan J. P., et al. Brain tumor cells in circulation are enriched for mesenchymal gene expression. Cancer Discovery 4(11):1299–1309 (2014). http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4221467
20. O'Malley K. J., et al. Proteomic analysis of patient tissue reveals PSA protein in the stroma of benign prostatic hyperplasia. Prostate 74(8):892–900 (2014). http://www.ncbi.nlm.nih.gov/pubmed/24711254
21. Movahedi A., et al. Remarkable anticancer activity of Teucrium polium on hepatocellular carcinogenic rats. Evidence-Based Complementary and Alternative Medicine 726724 (2014). http://dx.doi.org/10.1155/2014/726724
22. Akhavanfard S., et al. Inactivation of the tumor suppressor WTX in a subset of pediatric tumors. Genes Chromosomes Cancer 53(1):67–77 (2014). http://www.ncbi.nlm.nih.gov/pubmed/24249259
23. Ting D. T., et al. Single-cell RNA sequencing identifies extracellular matrix gene expression by pancreatic circulating tumor cells. Cell Reports 8(6):1905–1918 (2014). http://www.ncbi.nlm.nih.gov/pubmed/25242334
4
Cancer type
Gastroin
testinal
Lun
g
Breast
Prostate
Brain
Metastasis
Oth
ers
24. Adler A. S., et al. An integrative analysis of colon cancer identifies an essential function for PRPF6 in tumor growth. Genes & Development 28(10):1068–1084 (2014). http://genesdev.cshlp.org/content/28/10/1068.long
25. Koh Y. W., et al. MET and MST1R as prognostic factors for classical Hodgkin’s lymphoma. Modern Pathology 26(9):1172–1182 (2013). http://www.ncbi.nlm.nih.gov/pubmed/23558571
26. Weier C., et al. Nucleotide resolution analysis of TMPRSS2 and ERG rearrangements in prostate cancer. The Journal of Pathology 230(2):174–183 (2013). http://dx.doi.org/10.1002/path.4186
27. Urdinguio R. G., et al. Immune-dependent and independent antitumor activity of GM-CSF aberrantly expressed by mouse and human colorectal tumors. Cancer Research 73(1):395–405 (2013). http://www.ncbi.nlm.nih.gov/pubmed/23108143
28. Rheinbay E., et al. An aberrant transcription factor network essential for Wnt signaling and stem cell maintenance in glioblastoma. Cell Reports 3(5):1567–1579 (2013). http://www.ncbi.nlm.nih.gov/pubmed/23707066
29. Yu M., et al. Circulating breast tumor cells exhibit dynamic changes in epithelial and mesenchymal composition. Science 339(6119):580–584 (2013). http://dx.doi.org/10.1126/science.1228522
30. Gutschner T., et al. The noncoding RNA MALAT1 is a critical regulator of the metastasis phenotype of lung cancer cells. Cancer Research 73(3):1180–1189 (2013). http://www.ncbi.nlm.nih.gov/pubmed/23243023
31. Yu M., et al. RNA sequencing of pancreatic circulating tumour cells implicates WNT signalling in metastasis. Nature 487(7408):510–513 (2012). http://www.ncbi.nlm.nih.gov/pubmed/22763454
32. Kang Y. G., et al. Prognostic significance of S100A4 mRNA and protein expression in colorectal cancer. Journal of Surgical Oncology 105(2):119-124 (2012). http://www.ncbi.nlm.nih.gov/pubmed/21837681
33. Ting D. T., et al. Aberrant overexpression of satellite repeats in pancreatic and other epithelial cancers. Science 331(6017):593–596 (2011). http://dx.doi.org/10.1126/science.1200801
34. Lee K., et al. Expression of AIB1 protein as a prognostic factor in breast cancer. World Journal of Surgical Oncology 9:139 (2011) http://dx.doi.org/10.1186/1477-7819-9-139
5
Infectious disease
Viral strain/other (virus, bacterial, fungal, parasitic)
Hep
atitis viru
s
Pap
illoma
virus
Influ
enza
virus
Herp
es viru
s
Oth
er
1. Laiho J. E., et al. Application of bioinformatics in probe design enables detection of enteroviruses on different taxonomic levels by advanced in situ hybridization technology. Journal of Clinical Virology 69:165–171 (2015). http://www.ncbi.nlm.nih.gov/pubmed/26209400
2. El-Attar L. M., et al. Detection of non-primate hepaciviruses in UK dogs. Virology 484:93–102 (2015). http://www.ncbi.nlm.nih.gov/pubmed/26086431
3. Shapiro K. A., et al. Failure to detect human papillomavirus in focal cortical dysplasia type IIb. Annals of Neurology 78(1):63–67 (2015). http://www.ncbi.nlm.nih.gov/pubmed/25893423
4. Naccache S. N., et al. Diagnosis of neuroinvasive astrovirus infection in an immunocompromised adult with encephalitis by unbiased next-generation sequencing. Clinical Infectious Diseases First online: 07 January 2015. http://www.ncbi.nlm.nih.gov/pubmed/25572898
5. Lynn G. E., et al. Tissue distribution of the Ehrlichia muris-like agent in a tick vector. PLoS One 10(3):e0122007 (2015). http://www.ncbi.nlm.nih.gov/pubmed/25781930
6. Feng Y., et al. Molecular pathology analyses of two fatal human infections of avian influenza A(H7N9) virus. Journal of Clinical Pathology 68(1):57–63 (2015). http://www.ncbi.nlm.nih.gov/pubmed/25378539
7. Wieland S., et al. Simultaneous detection of hepatitis C virus and interferon stimulated gene expression in infected human liver. Hepatology 59(6):2121–2130 (2014). http://www.ncbi.nlm.nih.gov/pubmed/24122862
8. Duong F. H., et al. IFN-λ receptor 1 expression is induced in chronic hepatitis C and correlates with the IFN-λ3 genotype and with nonresponsiveness to IFN-α therapies. Journal of Experimental Medicine 211(5):857–868 (2014). http://www.ncbi.nlm.nih.gov/pubmed/24752298
9. Dill M. T., et al. Pegylated IFN-α regulates hepatic gene expression through transient Jak/STAT activation. Journal of Clinical Investigation 124(4):1568–1581 (2014). http://www.ncbi.nlm.nih.gov/pubmed/24569457
10. Wieland S. F., et al. Limited hepatitis B virus replication space in the chronically hepatitis C virus-infected liver. Journal of Virology 88:5184–5188 (2014). http://www.ncbi.nlm.nih.gov/pubmed/24522924
11. Seimon T. A., et al. Canine distemper virus: An emerging disease in wild endangered Amur tigers (Panthera tigris altaica). MBio 4(4):e00410-13 (2013). http://www.ncbi.nlm.nih.gov/pubmed/23943758
12. Anthony S. J., et al. Identification of a novel cetacean polyomavirus from a common dolphin (Delphinus delphis) with tracheobronchitis. PLoS One 8(7):e68239 (2013). http://www.ncbi.nlm.nih.gov/pubmed/23874559
13. Capua I., et al. Influenza A viruses grow in human pancreatic cells and cause pancreatitis and diabetes in an animal model. Journal of Virology 87(1):597–610 (2013). http://www.ncbi.nlm.nih.gov/pubmed/23097451
6
Viral strain/other (virus, bacterial, fungal, parasitic)
Hep
atitis viru
s
Pap
illoma
virus
Influ
enza
virus
Herp
es viru
s
Oth
er
14. Kuribayashi S., et al. Excessive cytokine response to rapid proliferation of highly pathogenic avian influenza viruses leads to fatal systemic capillary leakage in chickens. PLoS One 8(7):e68375 (2013). http://www.ncbi.nlm.nih.gov/pubmed/23874602
15. Seimon T. A., et al. A novel herpesvirus in 3 species of pheasants: mountain peacock pheasant (Polyplectron inopinatum), Malayan peacock pheasant (Polyplectron malacense), and Congo peafowl (Afropavo congensis). Veterinary Pathology 49(3):482–491 (2012). http://www.ncbi.nlm.nih.gov/pubmed/22075776
16. Everitt A. R., et al. IFITM3 restricts the morbidity and mortality associated with influenza. Nature 484(7395):519–523 (2012). http://www.ncbi.nlm.nih.gov/pubmed/22446628
17. Anthony S. J., et al. Emergence of fatal avian influenza in New England harbor seals. MBio 3(4):e00166-12 (2012). http://www.ncbi.nlm.nih.gov/pubmed/22851656
18. Kapoor A., et al. Characterization of a canine homolog of hepatitis C virus. PNAS 108(28):11608–11613 (2011). http://dx.doi.org/10.1073/pnas.1101794108
19. Honkavuori K. S., et al. Novel picornavirus in turkey poults with hepatitis, California, USA. Emerging Infectious Diseases 17(3):480–487 (2011). http://www.ncbi.nlm.nih.gov/pubmed/21392440
Neuroscience
Tissue type
Retin
a
Brain
Sp
inal
cord
Perip
heral
nerves
Oth
er
1. Huang J., et al. Bmp4 from the optic vesicle specifies murine retina formation. Developmental Biology 402(1):119–126 (2015). http://www.ncbi.nlm.nih.gov/pubmed/25792196
2. Valluy J., et al. A coding-independent function of an alternative Ube3a transcript during neuronal development. Nature Neuroscience 18(5):666–673 (2015). http://www.ncbi.nlm.nih.gov/pubmed/25867122
3. Johnson V., et al. Neurite mistargeting and inverse order of intraretinal vascular plexus formation precede subretinal vascularization in VLDLR mutant mice. PLoS ONE 10(7):e0132013 (2015). http://www.ncbi.nlm.nih.gov/pubmed/26177550
4. Usui Y., et al. Neurovascular crosstalk between interneurons and capillaries is required for vision. Journal of Clinical Investigation 125(6):2335–2346 (2015). http://www.ncbi.nlm.nih.gov/pubmed/25915585
5. Huang J., et al. Bmp4 from the optic vesicle specifies murine retina formation. Developmental Biology 402(1):119–126 (2015). http://www.ncbi.nlm.nih.gov/pubmed/25792196
7
Tissue type
Retin
a
Brain
Sp
inal
cord
Perip
heral
nerves
Oth
er
6. You X., et al. Neural circular RNAs are derived from synaptic genes and regulated by development and plasticity. Nature Neuroscience 18(4):603–610 (2015). http://www.ncbi.nlm.nih.gov/pubmed/25714049
7. Clarner T., et al. CXCL10 triggers early microglial activation in the cuprizone model. The Journal of Immunology 194(7):3400–3413 (2015).http://www.ncbi.nlm.nih.gov/pubmed/25725102
8. Solorzano C., et al. Primary afferent and spinal cord expression of gastrin-releasing peptide: message, protein, and antibody concern. Journal of Neuroscience 35(2):648–657 (2015). http://www.ncbi.nlm.nih.gov/pubmed/25589759
9. Pagani J. H., et al. Raphe serotonin neuron-specific oxytocin receptor knockout reduces aggression without affecting anxiety-like behavior in male mice only. Genes, Brain and Behavior 14(2):167–176 (2015). http://www.ncbi.nlm.nih.gov/pubmed/25677455
10. Iejima D., et al. HTRA1 (high temperature requirement A serine peptidase 1) gene is transcriptionally regulated by insertion/deletion nucleotides located at the 3’ end of the ARMS2 (age-related maculopathy susceptibility 2) gene in patients with age-related macular degeneration. Journal of Biological Chemistry 290(5):2784–2797 (2015). http://www.ncbi.nlm.nih.gov/pubmed/25519903
11. Wright C. B., et al. The Rpe65 rd12 allele exerts a semidominant negative effect on vision in mice. Investigative Ophthalmology and Visual Science 55(4):2500–2915 (2014). http://www.ncbi.nlm.nih.gov/pubmed/24644049
12. Wetzel-Smith M. K., et al. A rare mutation in UNC5C predisposes to late-onset Alzheimer’s disease and increases neuronal cell death. Nature Medicine 20(12):1452–1457 (2014). http://www.ncbi.nlm.nih.gov/pubmed/25419706
13. Soundararajan R., et al. Gene profiling of postnatal Mfrprd6 mutant eyes reveals differential accumulation of Prss56, visual cycle and phototransduction mRNAs. PLoS One 9(10):e110299 (2014). http://www.ncbi.nlm.nih.gov/pubmed/25357075
14. Ridderstad Wollberg A., et al. Pharmacological inhibition of the chemokine receptor CX3CR1 attenuates disease in a chronic-relapsing rat model for multiple sclerosis. PNAS 111(14):5409–5414 (2014). http://www.ncbi.nlm.nih.gov/pubmed/24706865
15. Matsushita K., et al. Chemokine (C-C motif) receptor 5 is an important pathological regulator in the development and maintenance of neuropathic pain. Anesthesiology 120(6):1491–1503 (2014). http://www.ncbi.nlm.nih.gov/pubmed/24589480
16. Chen Z., et al. FGF signaling activates a Sox9-Sox10 pathway for the formation and branching morphogenesis of mouse ocular glands. Development 141(13):2691–2701 (2014). http://www.ncbi.nlm.nih.gov/pubmed/24924191
17. Beirowski B., et al. Metabolic regulator LKB1 is crucial for Schwann cell-mediated axon maintenance. Nature Neuroscience 17(10):1351–1361 (2014). http://www.ncbi.nlm.nih.gov/pubmed/25195104
18. Beirowski B., et al. Metabolic regulator LKB1 is crucial for Schwann cell-mediated axon maintenance. Nature Neuroscience 17(10):1351–1361 (2014). http://www.ncbi.nlm.nih.gov/pubmed/25195104
8
Tissue type
Retin
a
Brain
Sp
inal cord
Perip
heral
nerves
Oth
er
19. Bardoni R., et al. Delta opioid receptors presynaptically regulate cutaneous mechanosensory neuron input to the spinal cord dorsal horn. Neuron 81(6):1312–1327 (2014). http://www.ncbi.nlm.nih.gov/pubmed/24583022
20. Miyajima M., et al. Leucine-rich α2-glycoprotein is a novel biomarker of neurodegenerative disease in human cerebrospinal fluid and causes neurodegeneration in mouse cerebral cortex. PLoS One 8(9):e74453 (2013). http://www.ncbi.nlm.nih.gov/pubmed/24058569
21. Epstein I., et al. Alternative polyadenylation and differential expression of Shank mRNAs in the synaptic neuropil. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 369(1633):20130137 (2013). http://www.ncbi.nlm.nih.gov/pubmed/24298140
22. Mustafi D., et al. Evolutionarily conserved long intergenic non-coding RNAs in the eye. Human Molecular Genetics 22(15):2992–3002 (2013). http://www.ncbi.nlm.nih.gov/pubmed/23562822
23. Ramos, A. D., et al. Integration of genome-wide approaches identifies lncRNAs of adult neural stem cells and their progeny in vivo. Cell Stem Cell 12(5):616–628 (2013). http://www.ncbi.nlm.nih.gov/pubmed/23583100
24. Bogdanik L. P., et al. Loss of the E3 ubiquitin ligase LRSAM1 sensitizes peripheral axons to degeneration in a mouse model of Charcot-Marie-Tooth disease. Disease Models & Mechanisms 6(3):780–792 (2013). http://www.ncbi.nlm.nih.gov/pubmed/23519028
25. Hurtado M. D., et al. Distribution of Y-receptors in murine lingual epithelia. PLoS One 7(9):e46358 (2012). http://www.ncbi.nlm.nih.gov/pubmed/23050020
Disease research, inflammatory/signaling, non-coding RNA, veterinary
Research area
Disease
research
Inflam
matory
/sig
nalin
g
Non
-codin
g
RN
A
Veterin
ary
Oth
er
1. Toyonaga T., et al. Osteopontin deficiency accelerates spontaneous colitis in mice with disrupted gut microbiota and macrophage phagocytic activity. PLoS One 10(8):e0135552 (2015). http://www.ncbi.nlm.nih.gov/pubmed/26274807
2. Rupanagudi K. V., et al. Cathepsin S inhibition suppresses systemic lupus erythematosus and lupus nephritis because cathepsin S is essential for MHC class II-mediated CD4 T cell and B cell priming. Annals of the Rheumatic Diseases 74(2):452–463 (2015). http://www.ncbi.nlm.nih.gov/pubmed/24300027
9
Research area
Disease
research
Inflam
matory
/sig
nalin
g
Non
-codin
g
RN
A
Veterin
ary
Oth
er
3. Huang L., et al. Partial hepatectomy induced long noncoding RNA inhibits hepatocyte proliferation during liver regeneration. PLoS One 10(7):e0132798 (2015). http://www.ncbi.nlm.nih.gov/pubmed/26207833
4. Goi Y., et al. Effect of silodosin, a selective α1A-adrenoceptor antagonist, on voiding behavior and bladder blood flow in a rat model of bladder outlet obstruction. European Journal of Pharmacology 764:489–496 (2015). http://www.ncbi.nlm.nih.gov/pubmed/26189024
5. Dalbøge L. S., et al. Neuromedin U inhibits food intake partly by inhibiting gastric emptying. Peptides 69:56–65 (2015). http://www.ncbi.nlm.nih.gov/pubmed/25895852
6. Huang L., et al. Partial hepatectomy induced long noncoding RNA inhibits hepatocyte proliferation during liver regeneration. PLoS One 10(7):e0132798 (2015). http://www.ncbi.nlm.nih.gov/pubmed/26207833
7. Castle J. W., et al. Therapeutic ultrasound: Increased HDL-cholesterol following infusions of acoustic microspheres and apolipoprotein A-I plasmids.Atherosclerosis 241(1):92–99 (2015). http://www.ncbi.nlm.nih.gov/pubmed/25969892
8. Tan E. M. S., et al. Characterisation of lymphocyte subpopulations in infantile haemangioma. Journal of Clinical Pathology 68:812-818 (2015) http://dx.doi.org/10.1136/jclinpath-2015-203073
9. Kubota K., et al. Hydroxy-α sanshool induces colonic motor activity in rat proximal colon: a possible involvement of KCNK9. American Journal of Physiology–Gastrointestinal and Liver Physiology 308(7):G579–590 (2015). http://www.ncbi.nlm.nih.gov/pubmed/25634809
10. Luo M., et al. Long non-coding RNAs control hematopoietic stem cell function. Cell Stem Cell 16(4):426–438 (2015). http://www.sciencedirect.com/science/article/pii/S1934590915000582
11. Clarner T., et al. CXCL10 triggers early microglial activation in the cuprizone model. Journal of Immunology 194(7):3400–3413 (2015). http://www.ncbi.nlm.nih.gov/pubmed/25725102
12. Boivin F. J., et al. Stromally expressed β-catenin modulates Wnt9b signaling in the ureteric epithelium. PLoS One 10(3):e0120347 (2015). http://www.ncbi.nlm.nih.gov/pubmed/25803581
13. Scarlett K., et al. The proangiogenic effect of Iroquois homeobox transcription factor Irx3 in human microvascular endothelial cells. Journal of Biological Chemistry 290(10):6303–6315 (2015). http://www.ncbi.nlm.nih.gov/pubmed/25512384
14. Mineshige T., et al. Expression of periostin in normal, atopic, and nonatopic chronically inflamed canine skin. Veterinary Pathology pii: 0300985815574007 (2015). http://www.ncbi.nlm.nih.gov/pubmed/25755133
15. Ma L., et al. Localization of APOL1 protein and mRNA in the human kidney: nondiseased tissue, primary cells, and immortalized cell lines. Journal of the American Society of Nephrology 26(2):339–348 (2015). http://www.ncbi.nlm.nih.gov/pubmed/25012173
10
Research area
Disease
research
Inflam
matory
/sig
nalin
g
Non
-codin
g
RN
A
Veterin
ary
Oth
er
16. Yoshimura H., et al. Cellular sources of tenascin-C in canine mammary carcinomas. Veterinary Pathology 52(1)92–96 (2015). http://www.ncbi.nlm.nih.gov/pubmed/24565830
17. Imajo M., et al. Dual role of YAP and TAZ in renewal of the intestinal epithelium. Nature Cell Biology 17(1):7–19 (2015). http://www.ncbi.nlm.nih.gov/pubmed/25531778
18. Michishita M., et al. Increased expression of 5-HT(2A) and 5-HT(2B) receptors in detrusor muscle after partial bladder outlet obstruction in rats. Biomedical Research 36(3):187–194 (2015). http://www.ncbi.nlm.nih.gov/pubmed/26106048
19. Yoshimura H., et al. Simultaneous detection of different RNAs using a novel branched DNA in situ hybridization method. Journal of Nippon Medical School 81(2):62–63 (2014). http://www.ncbi.nlm.nih.gov/pubmed/24805090
20. Joo J. H., et al. Role of Pnn in alternative splicing of a specific subset of the lncRNAs of the corneal epithelium. Molecular Vision 20:1629–1642 (2014). http://www.ncbi.nlm.nih.gov/pubmed/25489234
21. Tasseff R., et al. Mouse hair cycle expression dynamics modeled as coupled mesenchymal and epithelial oscillators. PLoS Computational Biology 10(11):e1003914 (2014). http://www.ncbi.nlm.nih.gov/pubmed/25375120
22. Ting D. T., et al. Single-cell RNA sequencing identifies extracellular matrix gene expression by pancreatic circulating tumor cells. Cell Reports 8(6):1905–1918 (2014). http://www.ncbi.nlm.nih.gov/pubmed/25242334
23. Huang Y. S., et al. Urinary Xist is a potential biomarker for membranous nephropathy. Biochemical and Biophysical Research Communications 452(3):415–421 (2014). http://www.ncbi.nlm.nih.gov/pubmed/25157805
24. Wu H., et al. LincRNA-uc002yug.2 involves in alternative splicing of RUNX1 and serves as a predictor for esophageal cancer and prognosis. Oncogene 34(36):4723–4734 (2015). http://www.ncbi.nlm.nih.gov/pubmed/25486427
25. Fujii E., et al. Histopathological characteristics of human non-tumor thyroid tissues in a long-term model of adenomatous goiter xenografts in the NOD/Shi-scid, IL-2R(null) mouse. Experimental and Toxicologic Pathology 66(4):203–209 (2014). http://www.ncbi.nlm.nih.gov/pubmed/24589354
26. Holembowski L., et al. TAp73 is essential for germ cell adhesion and maturation in testis. Journal of Cell Biology 204(7):1173–1190 (2014). http://www.ncbi.nlm.nih.gov/pubmed/24662569
27. Farkas D., et al. CXCR4 inhibition ameliorates severe obliterative pulmonary hypertension and accumulation of C-kit+ cells in rats. PLoS One 9(2):e89810 (2014). http://www.ncbi.nlm.nih.gov/pubmed/24587052
28. Guo S., et al. Antisense oligonucleotide treatment ameliorates alpha-1 antitrypsin-related liver disease in mice. Journal of Clinical Investigation 124(1):251–261 (2014). http://www.ncbi.nlm.nih.gov/pubmed/24355919
11
Research area
Disease
research
Inflam
matory
/sig
nalin
g
Non
-codin
g
RN
A
Veterin
ary
Oth
er
29. Hung G., et al. Characterization of target mRNA reduction through in situ RNA hybridization in multiple organ systems following systemic antisense treatment in animals. Nucleic Acid Therapeutics 23(6):369–378 (2013). http://www.ncbi.nlm.nih.gov/pubmed/24161045
30. Patra C., et al. Organ-specific function of adhesion G protein-coupled receptor GPR126 is domain-dependent. PNAS 110(42):16898–16903 (2013). http://www.ncbi.nlm.nih.gov/pubmed/24082093
31. Goi Y., et al. Effects of silodosin, a selective α1A-adrenoceptor antagonist, on bladder blood flow and bladder function in a rat model of atherosclerosis induced chronic bladder ischemia without bladder outlet obstruction. Journal of Urology 190(3):1116–1122 (2013). http://www.ncbi.nlm.nih.gov/pubmed/23545103
32. Seimon T. A., et al. Canine distemper virus: An emerging disease in wild endangered Amur tigers (Panthera tigris altaica). MBio 4(4) (2013). http://www.ncbi.nlm.nih.gov/pubmed/23943758
33. Mustafi D., et al. Evolutionarily conserved long intergenic non-coding RNAs in the eye. Human Molecular Genetics 22(15):2992–3002 (2013). http://www.ncbi.nlm.nih.gov/pubmed/23562822
34. Anthony S. J., et al. Identification of a novel cetacean polyomavirus from a common dolphin (Delphinus delphis) with tracheobronchitis. PLoS One 8(7):e68239 (2013). http://www.ncbi.nlm.nih.gov/pubmed/23874559
35. Ramos, A. D., et al. Integration of genome-wide approaches identifies lncRNAs of adult neural stem cells and their progeny in vivo. Cell Stem Cell 12(5):616–628 (2013). http://www.ncbi.nlm.nih.gov/pubmed/23583100
36. Gutschner T., et al. The noncoding RNA MALAT1 is a critical regulator of the metastasis phenotype of lung cancer cells. Cancer Research 73(3):1180–1189 (2013). http://www.ncbi.nlm.nih.gov/pubmed/23243023
37. Capua I., et al. Influenza A viruses grow in human pancreatic cells and cause pancreatitis and diabetes in an animal model. Journal of Virology 87:597–610. http://www.ncbi.nlm.nih.gov/pubmed/23097451
38. Gröger N., et al. Targeted mutation of SLC4A5 induces arterial hypertension and renal metabolic acidosis. Human Molecular Genetics 21(5):1025–1036 (2012). http://www.ncbi.nlm.nih.gov/pubmed/22082831
39. Anthony S. J., et al. Emergence of fatal avian influenza in New England harbor seals. MBio 3(4):e00166–12 (2012). http://www.ncbi.nlm.nih.gov/pubmed/22851656
40. Frolova E. G., et al. Thrombospondin-4 regulates fibrosis and remodeling of the myocardium in response to pressure overload. FASEB Journal 26(6):2363–2373 (2012). http://www.ncbi.nlm.nih.gov/pubmed/22362893
41. Seimon T. A., et al. A novel herpesvirus in 3 species of pheasants: mountain peacock pheasant (Polyplectron inopinatum), Malayan peacock pheasant (Polyplectron malacense), and Congo peafowl (Afropavo congensis). Veterinary Pathology 49(3):482–491 (2012). http://www.ncbi.nlm.nih.gov/pubmed/22075776
12
Research area
Disease
research
Inflam
matory
/sig
nalin
g
Non
-codin
g
RN
A
Veterin
ary
Oth
er
42. Honkavuori K. S., et al. Novel picornavirus in turkey poults with hepatitis, California, USA. Emerging Infectious Diseases 17(3):480–487 (2011). http://www.ncbi.nlm.nih.gov/pubmed/21392440
43. Ting D. T., et al. Aberrant overexpression of satellite repeats in pancreatic and other epithelial cancers. Science 331(6017):593–596 (2011). http://dx.doi.org/10.1126/science.1200801
44. Kapoor A., et al. Characterization of a canine homolog of hepatitis C virus. PNAS 108(28):11608–11613 (2011). http://dx.doi.org/10.1073/pnas.1101794108
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