UTSW Neonatal-Perinatal Fellow Scholarship...UTSW Neonatal-Perinatal Fellow Scholarship 1 This...

UTSW Neonatal-Perinatal Fellow Scholarship

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This document contains all publications and abstracts related to work accomplished during

fellowship, as well as grants from past fellows, for 2010-2015.

The names of the fellows are underlined. Rev 6/19/2015

JOURNAL ARTICLES

Original Peer-Reviewed Manuscripts

2015

Cantey J, Lopez-Medina E, Nguyen S, Doern CD, Garcia C. Empiric Antibiotics for

Serious Bacterial Infection in Young Infants: Opportunities for Stewardship. Pediatric

Emergency Care 2015, in press

Cantey JB, Gaviria-Agudelo C, McElvania TeKippe E, Doern CD. Lack of clinical utility

of urine Gram stain for suspected urinary tract infection in pediatric patients. J Clin

Microbiol. 2015 Feb 4

Lopez-Medina E, Cantey JB, Sánchez PJ. The Mortality of Neonatal Herpes Simplex

Virus Infection. The Journal of pediatrics 04/2015; DOI: 10.1016/j.jpeds.2015.03.004

Mayor R, Finch K, Zehr J, Morselli E, Neinast M, Frank A, Hahner L, Wang J, Rakheja

D, Palmer B, Rosenfeld C, Savani R, Clegg D. Maternal high fat diet is associated with

impaired fetal lung development. American Journal of Physiology - Lung Cellular and

Molecular Physiology, in press

Weydig HM, Veltkamp D, Kakkilaya V, Stumpf K, Waber LJ, Brion LP. Index of

Suspicion in the Nursery: Progressive lethargy in a four-day-old term infant.

NeoReviews, in press

2014

Cantey JB, Jamison R, Baldridge C, Shanley LA. Late and very-late onset group B

Streptococcus sepsis: one and the same? World Journal of Pediatrics. 2014; 10(1): 24-28.

Cantey JB, Lopez-Medina E, Nguyen S, et al. Empiric antibiotics for serious bacterial

infection in young infants: Role for stewardship. Accepted to Pediatric Emergency Care,

March 2014.

Cantey JB, Sánchez PJ, Tran J, et al. Pertussis: A persistent cause of morbidity and

mortality in young infants. Journal of Pediatrics. 2014; 165(6): 1489-1492.

Cantey JB, Wozniak PS, Sánchez PJ. Prospective Surveillance of Antibiotic Use in the

Neonatal Intensive Care Unit: Results from the SCOUT Study. The Pediatric Infectious

Disease Journal. PMID: 25191849

Lal CV, Mir IN, Kelley E, Weprin BE, Sengupta AL, Booth TN, Brion LP.

Hypomagnesemia Secondary to Cerebrospinal Fluid Losses in a Patient with Congenital

Hydrocephalus. J Perinatology, 2014; 34, 640–641. PMID:25073495

Lal CV, Schwarz MA. Vascular Mediators in Chronic Lung Disease of Infancy: Role of

Endothelial Monocyte Activating Polypeptide II (EMAP II). Birth Defects Res A Clin

Mol Teratol. 2014 Mar;100(3):180-8. doi: 10.1002/bdra.23234. Epub 2014 Mar 12.


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PMID:24619875

LeVan JM, Brion LP, Wrage LA, Gantz MG, Wyckoff MH, Sánchez PJ, Heyne R, Jaleel

M, Finer NN, Carlo WA, Das A, Stoll BJ, Higgins RD, on behalf of the Eunice Kennedy

Shriver NICHD Neonatal Research Network, Bethesda, MD. Change in Practice After

The Surfactant, Positive Pressure, and Oxygenation Randomized Trial. Arch Dis Child

Fetal Neonatal 2014;99: F386–F390. PMID: 24876196

Mikhael M, Brown S, Rosenfeld CR. Serial Neutrophil Values Facilitate Predicting the

Absence of Neonatal Early-Onset Sepsis. J Pediatr. 2014;164:522-8.

Oliveira C, Morris M, Mistrot J, Cantey JB, Doern C, Sánchez PJ. Brain magnetic

resonance imaging of infants with bacterial meningitis: an eleven year experience.

Journal of Pediatrics. 2014; 165(1): 134-139.

Rac MW, Bryant S, Cantey JB, et al. Maternal titers after adequate syphilotherapy during

pregnancy. Accepted to American Journal of Obstetrics and Gynecology, May 2014.

Rac MW, Bryant SN, McIntire DD, Cantey JB, Twickler DM, Wendel GD Jr, Sheffield

JS. Progression of ultrasound findings of fetal syphilis after maternal treatment.

Am J Obstet Gynecol. 2014 Oct;211(4):426.e1-6.

Sen SK, Mayor R, Engle WD, Blumenschein SD, Brion LP. Index of suspicion.

Hyperbilirubinemia without jaundice in a neonate. NeoReviews, in press

Sundgren NC, Vongpatanasin W, Boggan BM, Tanigaki K, Yuhanna IS, Chambliss KL,

Mineo C, Shaul PW. IgG Receptor FcγRIIB Plays a Key Role in Obesity-Induced

Hypertension. Hypertension. 2014 Nov PMID:25368023

2013

Bennett KM, Afanador MD, Lal CV, Xu H, Persad E, Legan SK, Chenaux G, Dellinger

M, Savani RS, Dravis C, Henkemeyer M, and Schwarz MA. Ephrin-B2 Reverse

Signaling Modulates α5β1 integrin mediated Fibronectin Deposition and Distal Lung

Compliance. ATS Red Journal (American Journal of Respiratory Cell and Molecular

Biology) 2013 Oct;49(4):680-7

Cantey JB, Bascik SL, Heyne NG, Gonzalez JR, Jackson GL, Rogers VL, Sheffield JS,

Treviño S, Sendelbach D, Wendel GD, Sánchez PJ. Prevention of mother-to-infant

transmission of influenza during the postpartum period. Am J Perinatol. 2013

Mar;30(3):233-40

Cantey JB, Pritchard MA, Sánchez PJ. Bone Lesions in an Infant with Congenital

Parvovirus B19 Infection. Pediatrics 2013 May;131(5):e1659-63

Cantey JB, Sánchez PJ. Neonatal herpes simplex virus infections: past progress and

future challenges. Pediatr Infect Dis J. 2013 Nov;32(11):1205-7

Cantey JB, Sreeramoju P, Jaleel M, et al. Prompt Control of an Outbreak Caused by

Extended-Spectrum Beta Lactamase-Producing Klebsiella pneumoniae in a Neonatal

Intensive Care Unit. J Pediatr. 2013 Sep;163(3):672-9.e1-3.


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DuPont TL, Chalak LF, Morriss MC, Burchfield PJ, Christie L, Sánchez PJ. Short Term

Outcomes of Newborns with Perinatal Acidemia Who Are Not Eligible for Systemic

Hypothermia Therapy. J Pediatr. 2013 Jan;162(1):35-41. PMID: 22871488

Kapadia VS, Chalak LF, DuPont TL, Rollins NK, Brion LP, Wyckoff MH. Perinatal

asphyxia with hyperoxemia within the first hour of life is associated with moderate to

severe hypoxic-ischemic encephalopathy. J Pediatr. 2013 Oct;163(4):949-54.

Kapadia VS, Chalak LF, Sparks JE, Allen JR, Savani RC, Wyckoff MH. Resuscitation of

preterm neonates with limited versus high oxygen strategy. Pediatrics. 2013

Dec;132(6):e1488-96

LeVan JM, Wyckoff MH, Ahn C, Heyne R, Sánchez PJ, Chalak L, Jaleel MA, Burchfield

PJ, Christie L, Soll R, Badger GJ, Brion LP. Change in Process of Care Among Non–

Enrolled Patients During and After a Randomized Trial, Pediatrics, Pediatrics. 2013;

132:e960-70

Stumpf K, Thompson T, Sánchez PJ. Rotavirus Vaccination of Very Low Birth Weight

Infants at Discharge From the NICU. Pediatrics. 2013 Sep;132(3):e662-5

2012

Cantey JB, Mejías A, Wallihan R, Doern C, Brock E, Salamon D, Marcon M, Sánchez PJ.

Use of blood polymerase chain reaction for diagnosis of herpes simplex virus infection. J

Pediatr. 2012 Aug;161(2):357-61

Foley JP, Lam D, Jiang H, Liao J, Cheong N, McDevitt TM, Zaman A, Wright JR, Savani

RC. Toll-like Receptor 2 (TLR2), Transforming Growth Factor-β, Hyaluronan (HA), and

Receptor for HA-mediated Motility (RHAMM) Are Required for Surfactant Protein A-

stimulated Macrophage Chemotaxis. J Biol Chem. 2012 Oct 26;287(44):37406-19

Frankfurt JA, Duncan AF, Heyne RJ, Rosenfeld CR. Renal Function and Systolic Blood

Pressure in Very-Low-Birth-Weight Infants 1-3 Years of Age. Pediatric Nephrology 2012;

27(12):2285-91, PMID: 22832668

2011

Chalak LF, Barber CA, Hynan L, Garcia D, Christie L, Wyckoff MH. End-tidal CO2

Detection of an Audible Heart Rate During Neonatal Cardiopulmonary Resuscitation

Following Asystole in Asphyxiated Piglets. Pediatric Res 2011; 69:401-405

Duncan AF, Heyne RJ, Morgan JS, Ahmad N, Rosenfeld CR. Elevated systolic blood

pressure in preterm very-low-birth-weight infants ≤3 years of life. Pediatr Nephrol

2011;26:1115–21

Sundgren NC, Zhu W, Yuhanna IS, Chambliss K, Ahmed M, Tanigaki K, Umetani M,

Mineo C, Shaul PW. Coupling of FcγRI to FcγRIIB by Src Kinase Mediates C-reactive

Protein Impairment of Endothelial Function. Circ Res, 109 (10), 2011 PMC321509

2010

Kapadia V, Embers D, Wells E, Lemler M, Rosenfeld CR. Prenatal Closure of the Ductus

Arteriosus and Maternal Ingestion of Anthocyanins. J Perinatol 30:291-4, 2010


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Khan L, Rosenfeld CR, Liu X, Magness RR. Regulation of the cGMP-cPKG pathway

and large- conductance Ca2+-activated K+ channels uterine arteries during the ovine

ovarian cycle. Am J Physiol Endocrin Metabol, 298: E222-E228, 2010

Reviews

2015

Cantey JB, Milstone AM. Bloodstream Infections: Epidemiology and Resistance. Clinics

in perinatology 03/2015; 42(1):1-16

Cantey JB, Sisman J, The etiology of lenticulostriate vasculopathy and the role of

congenital infections, Early Hum Dev (2015), http://dx.doi.org/10.1016/j.earlhumdev

Tanigaki K, Sundgren N, Khera A, Vongpatanasin W, Mineo C, Shaul PW. Fcγ

Receptors and Ligands and Cardiovascular Disease. Circ Res. 2015 Jan 16;116(2):368-

384.

2014

Cantey JB, Patel SJ. Antimicrobial stewardship in the NICU. Infectious Disease Clinics

of North America. 2014; 28(2): 247-261

Mir IN, Chalak LF. Serum biomarkers to evaluate the integrity of the neurovascular unit.

Early Human Development, 2014 Oct;90(10):707-11.

2012

Kapadia V, Wyckoff MH. Chest Compressions for Bradycardia or Asystole in Neonates.

Clin Perinatol 2012 Dec;39(4):833-42.

Chapters

2014

Cantey JB, Sanchez PJ. Syphilis. In: Cabana MD, et al., eds. The 5-Minute Pediatric

Consult. 7th Ed. Philadelphia, PA; Lippincott Williams & Wilkins: 2014.

Cantey JB, Jaleel M. Neonatal resuscitation. In: Shah SS, Alverson B, Ronan J, eds. Step

Up to Pediatrics. Philadelphia, PA; Lippincott Williams & Williams: 2013.

Kapadia VS, Brion LP. Neonatal jaundice. In: McInerny T, Adam H, Campbell D, DeWitt

T, Foy J, Kamat D, eds. American Academy of Pediatrics Textbook of Pediatric Care. Elk

Grove Village, IL: American Academy of Pediatrics, in press

2013

Shanley LA, Cantey JB. Congenital infections. In: Shah SS, Alverson B, Ronan J, eds.

Step Up to Pediatrics. Philadelphia, PA; Lippincott Williams & Williams: 2013.

2012

Kaufman D, Zanelli S, Cantey JB, Sánchez PJ. Chapter 13: Neonatal meningitis: current

treatment options. In: Neurology: Neonatal Questions and Controversies. 2nd Ed.

Philadelphia, PA; Elsevier; 2012: 181-201.


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ABSTRACTS

2015

Cantey JB. Surveillance and Correction of Unnecessary Antibiotic Therapy (SCOUT) in

the Neonatal Intensive Care Unit (NICU): It Can Be Done! Platform presentation at

Pediatric Academic Societies Annual Meeting, San Diego, CA, 4/27/15

Cantey JB. Duration of Antimicrobial Therapy for Bloodstream Infections (BSI) in Very-

Low-Birth-Weight (VLBW) Infants: Implications for Antibiotic Stewardship. Poster

presentation at Pediatric Academic Societies Annual Meeting, San Diego, CA, 4/28/15

Cantey JB. Screening for Neonatal Herpes Simplex Virus (HSV) Infection with Serum

Alanine Aminotransferase (ALT): How Good Is It? Poster presentation at Pediatric

Academic Societies Annual Meeting, San Diego, CA, 4/28/15

Cantey JB. Neonates with Normal Physical Examination and Nonreactive Nontreponemal

Test Results: What's the Risk for Congenital Syphilis? Poster presentation at Pediatric

Academic Societies Annual Meeting, San Diego, CA, 4/28/15

Cantey JB. Is Prolonged Rupture of Membranes a Risk Factor for Early-Onset Sepsis in

Preterm Infants? Poster presentation at Pediatric Academic Societies Annual Meeting,

San Diego, CA, 4/28/15

DeVries LD, Jaleel M, Kapadia V, Heyne R, Brion LP. Relationship between Pulmonary

Hypertension and Outcomes among Infants with Bronchopulmonary Dysplasia Who

Undergo Surgery. Poster presentation at 86th Perinatal & Developmental Medicine

Symposium “Perinatal Genomics” Aspen, Colorado, June 4‐7, 2015

Halling C, Sparks JE, Christie L, Wyckoff MH. Use and Efficacy of Lower Versus

Higher Doses of Endotracheal (ETT) Epinephrine During Neonatal Cardiopulmonary

Resuscitation (CPR) in the Delivery Room. Platform presentation at Pediatric Academic

Societies Annual Meeting, San Diego, CA, 4/27/15

Mir IN, Cantey JB, Chalak LF. Placenta "The Least Understood Organ''- A Journey from

Early Animistic Origins to the Current Human Placental Project. Poster Symposium at

Pediatric Academic Societies Annual Meeting, San Diego, CA, 4/25/15

Mir IN, Welch SJ, Brown LS, Kandru G, Lal CV, Rosenfeld CR, Chalak LF. Placental

Pathology is Associated with Severity of Neonatal Encephalopathy (NE), Death and

Neurodevelopment Impairment at 18-24 Months. Poster presentation at SRI Annual

Meeting, San Francisco, March 28, 2015

Moallem M, Talavera MM, Cantey JB, Kandefer S, Stoll BJ, Sanchez PJ, and the NICHD

Neonatal Research Network (NRN). Twelve Years of Bloodstream Infections (BSI) and

Meningitis (M) in Preterm Infants with Necrotizing Enterocolitis (NEC): The NEC-BSI

Study. Presentation at Pediatric Academic Societies Annual Meeting, San Diego, CA,

April 2015

Pyle AK, Cantey JB, Wozniak PS, Hynan LS, Sanchez PJ. Antibiotic Exposure and

Adverse Outcomes in Preterm, Very-Low-Birth-Weight (VLBW) Infants: Each Day

Matters! Poster presentation at Pediatric Academic Societies Annual Meeting, San Diego,

CA, 4/28/15


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Sheehan JW, Jurado J, Allen T, Frost MS. Using QI Methodologies To Improve

Compliance with ACGME Requirements: Increasing Completed Parent Evaluations in a

Neonatal Fellowship Program. Poster presentation at Pediatric Academic Societies

Annual Meeting, San Diego, CA, 4/27/15

Sheehan JW, Pritchard MA, Brown LS, Heyne RJ, Jaleel MA, Engle WD, Brion LP..

Withdrawal of Support in Preterm Infants with Periventricular Hemorrhagic Infarction.

Poster presentation at Pediatric Academic Societies Annual Meeting, San Diego, CA,

4/28/15

Weydig HM, Jaleel MA, Frost M, Brion LP. Parkland QI Bundle: Reducing Mortality

and Morbidity in Extremely Low Gestational Age Neonates (ELGANs) at Parkland.

Poster presentation at AAP National Conference and Exhibition, Washington DC,

10/23/2015

2014

Cantey JB, Doern C. “A Defective and Imperfect” Method: H. Christian Gram and the

History of the Gram Stain. Platform presentation at Pediatric Academic Societies Annual

Meeting 2014

Cantey JB, Nguyen S, Wozniak P, et al. Antibiotic stewardship in the neonatal intensive

care unit (NICU): Metrics matter! Presented as poster at the Infectious Disease Society

of America Annual Meeting, Philadelphia, PA, October 2014.

Cantey JB, Stagno SB, Sánchez PJ. Protozoa, Parotids, and Progress: The Convoluted

History of Congenital Cytomegalovirus (cCMV) Infection. Platform presentation at

Pediatric Academic Societies Annual Meeting 2014

Cantey JB, Wozniak PS, Sánchez PJ. The Conundrum of Pneumonia Treatment in the

NICU: Can Variation Inform Antibiotic Stewardship? Poster presentation at Pediatric

Academic Societies Annual Meeting 2014

DeVries, Kakkilaya V. Oxygen Targeting for Preterm Infants. Oral presentation at Levine

Children’s Hospital Quality Improvement Coaching Conference (LCH QuICC),

Charlotte, NC, September 17-19, 2014

Halling, C, Sparks JE, Wyckoff MH. Use and Efficacy of lower versus higher

endotracheal (ETT) epinephrine during neonatal cardiopulmonary resuscitation in the

delivery room. Poster presentation at: the American Academy of Pediatrics Section on

Perinatal Pediatrics 85th Perinatal & Developmental Medicine Symposium entitled,

“Engaging in Perinatal Global Health: Can, Should, Will, When, and How?” Fort Myers,

FL, 11/13-16/14

Kagan E, Banks AL, Marculescu C, Cantey JB, Salgado C. Risk factors for peripherally

inserted central catheter (PICC) bloodstream infection (BSI). Presented as platform at the

Infectious Disease Society of America Annual Meeting, Philadelphia, PA, October 2014.

Lal CV, Liao J, Cheong N, Longoria C, Cuna A, M. Faye-Petersen O, Kelly DR,

Ambalavanan N, Savani RC. CD44 is necessary for increased lung IL1β/TGFβ and

decreased alveolarization in mice exposed to neonatal hyperoxia, and is elevated in


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preterm infants with BPD. Platform presentation at Pediatric Academic Societies Annual

Meeting, Vancouver, May 4, 2014

Mayor RS, Hill B, Zehr J, Neinast M, Morselli E, Lal C, Hahner L, Savani R, Clegg D. In

Utero Exposure to Maternal High Fat Diet Increases Fetal Lung Inflammation Impairing

Lung Development. Platform presentation at Pediatric Academic Societies Annual

Meeting, Vancouver, May 5, 2014

Mayor RS. Maternal Diet Impairs Fetal Lung Development. Platform presentation at

American Academy of Pediatrics (AAP) National Conference and Exhibition, San Diego,

CA, October 11, 2014

Mir IN, Welch SJ, Brown LS, Kandru G, Lal CV, Rosenfeld CR, Chalak LF. Placental

Pathology is Associated with Severity of Neonatal Encephalopathy (NE), Death and

Neurodevelopment Impairment at 18-24 Months. Poster presentation at Pediatric

Academic Societies Annual Meeting, Vancouver, May 5, 2014

Mir IN, Welch SJ, Brown LS, Lal CV, Rosenfeld CR, Chalak LF. Placental Pathology is

Associated with Severity of Neonatal Encephalopathy and Neurodevelopmental Outcome

at 18-24 Months of Age. Platform presentation at: Section on Perinatal Pediatrics, 21st

South Central Conference on Perinatal Research, Lakeway Resort, Austin, Texas,

October 27‐29, 2014

Morgan D, Braykov N, Schweizer M, Cantey JB, et al. Factors associated with

optimizing empiric antibiotic therapy in six hospitals. Presented as platform at the

Infectious Disease Society of America Annual Meeting, Philadelphia, PA, October 2014.

Pyle A, Cantey JB, Brown LS, Heyne R, Heyne E, Atok A, Brammer E, Lair L, Sánchez

PJ. Antibiotic Exposure in Very-Low-Birth-Weight (VLBW) Infants in the NICU:

Another Marker for Obesity? Poster presentation at Pediatric Academic Societies Annual

Meeting 2014

Rac MW, Bryant S, Cantey JB, et al. Progression of ultrasound findings of fetal syphilis

following maternal treatment. Presented as platform at the Society for Maternal-Fetal

Medicine annual meeting, New Orleans, LA, February 2014.

Rac MW, Bryant S, Cantey JB, et al. Maternal titers after adequate syphilotherapy

during pregnancy. Presented as poster at the Society for Maternal-Fetal Medicine annual

meeting, New Orleans, LA, February 2014.

Ronchi A, Torres L, Zeray F, Boatman C, Owen KE, Shoup AG, Cantey JB, Varghese S,

Pugni L, Mosca F, Ahmed A, Michaels M, Sánchez PJ. How Asymptomatic is the

“Asymptomatic” Neonate with Congenital Cytomegalovirus (cCMV) Infection? Platform

presentation at Pediatric Academic Societies Annual Meeting 2014

Ronchi A, Torres L, Zeray F, Cantey JB, et al. How asymptomatic is the “asymptomatic”

neonate with congenital cytomegalovirus infection? Presented as platform at Pediatric

Academic Society Annual Meeting, Vancouver, BC, May 2014.


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Stine CN, Koch J, Brown LS, Chalak L, Kapadia V, Wyckoff MH. Quantitative End-tidal

CO2 (ETCO2) predicts return of spontaneous circulation (ROSC) during infant CPR.

Platform presentation at Pediatric Academic Societies Annual Meeting, Vancouver, May

3, 2014

Weydig H. Presentation at Levine Children’s Hospital Quality Improvement Coaching

Conference (LCH QuICC), Charlotte, NC, September 17-19, 2014

White NO, Cantey JB, Dulaurier M, Mejias A, Sanchez PJ. Management of newborns

delivered to women with active genital herpes simplex virus (HSV) lesions: is current

guidance optimal? Platform presentation at Pediatric Academic Societies Annual Meeting

2014

Wozniak PS, Cantey JB, Zeray F, Leos NK, Sheffield J, Wendel GD, Sánchez PJ.

Nineteen Years of Congenital Syphilis (CS) in Dallas: Progress and Persistence! Platform

presentation at Pediatric Academic Societies Annual Meeting 2014

2013

Cantey JB, Wozniak P, Sánchez PJ. Antibiotic Stewardship in the Neonatal Intensive

Care Unit (NICU): Improvement Needed! Platform Presentation at Pediatric Academic

Societies Annual Meeting, 2013 (Washington DC)

Kapadia VS, Kakkilaya V, Lal CV, Savani RC, Wyckoff MH. Delivery room (DR)

Resuscitation using 2011 Neonatal Resuscitation Program (NRP) Oxygen Guidelines is

Associated with Reduced Bronchopulmonary Dysplasia (BPD) in Preterm Neonates.

Platform Presentation to Pediatric Academic Societies Annual Meeting, 2013

(Washington DC)

Lal CV, Awasthi N, Xu H, Schwarz AM, Savani RC, Schwarz Re, Schwarz MA.

Endothelial Monocyte Activating Polypeptide II (EMAP II) Induces Bronchopulmonary

Dysplasia (BPD)-Like Phenotype in Uninjured Mice, and Hyperoxia-induced BPD is

Improved by an EMAP II Blocking Antibody. Platform Presentation at Pediatric

Academic Societies Annual Meeting, 2013 (Washington DC)

Lal CV, Cantey JB, Varghese S, Scheid LM, Trevino S, Jaleel M, Sanchez PJ. Obtaining

Blood Cultures (BC) in the Neonatal Intensive Care Unit (NICU): Central, Peripheral or

Both? Poster Presentation at Pediatric Academic Societies Annual Meeting, 2013

(Washington DC)

Lal CV, Awasthi N, Xu H, Schwarz AM, Schwarz R, Savani RC, Schwarz MA.

BPD:Development of a Developmental Therapy. Platform presentation at American

Academy of Pediatrics (AAP) National Conference and Exhibition, Orlando, FL,

10/25/13

Levan J, Brion LP, Wrage LA, on behalf of the NICHD NRN. Changes in therapy and

outcomes associated with the SUPPORT Trial. Poster presentation at PAS, Washington

DC, May 5, 2013

Mayor R, Finch K, Davis K, Zehr J, Neinast M, Bills J, Savani RC, Clegg D. In Utero

Exposure to Maternal High Fat Diet Increases Fetal Lung Inflammation Impairing Lung

Development. Poster presentation at American Academy of Pediatrics (AAP) National


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Conference and Exhibition, Orlando, FL, 10/25/13

Motta CL, Wyckoff MH. Does NRP Need a New Rule for Appropriate Endotracheal

Tube (ETT) Depth for Newborns < 1000g? Poster Presentation at Pediatric Academic


Motta CL, Scott W, Mahony L, Koch J, Wyckoff MH, Reisch J, Brion LP. Association of

Congenital Heart Disease and Necrotizing Enterocolitis in Preterm Infants.

Poster presentation at 82nd Perinatal & Developmental Medicine Symposium

“The Microbiome in Perinatal Health and Disease,” Aspen, Colorado, June 6-9,

2013

Poster presentation at American Academy of Pediatrics (AAP) National

Conference and Exhibition, Orlando, FL, 10/25/13

Platform presentation at Section on Perinatal Pediatrics, 20th South Central

Conference on Perinatal Research, Lakeway Resort, Austin, Texas, 10/29/13

Stine C, Wyckoff MH. Success of the Neonatal Resuscitation Program Algorithm in the

Neonatal Intensive Care Unit (NICU). Poster Presentation at Pediatric Academic


Stine C, Wyckoff MH. Cardiopulmonary Resuscitation (CPR) in the Neonatal Intensive

Care Uit (NICU): Asystole versus Bradycardia. AAP NCE. Orlando Florida. 2013. Poster

Presentation.

2012

Cheong N, Liao J, Marinescu C, Jeyaraj J, Longoria C, Wu Q, Yuhanna IS, Cao G,

DeLisser HM, Shaul PW, Savani RC. Hyaluronan and Its Receptor RHAMM Are

Necessary and Sufficient for Akt and eNOS Phosphorylation To Activate Nitric Oxide

Production. Platform presentation at PAS, Boston, MA, 4/30/12

Frankfurt J, Duncan A, Heyne R, Rosenfeld, CR. Growth Patterns in Preterm Very-Low-

Birth-Weight (PT-VLBW) Infants at 1-3yrs Correlate with Elevated Serum Leptin.

Platform Presentation at Pediatric Academic Societies and Asian Society for Pediatric

Research (PAS/ASPR) in Boston, Massachusetts, April 28-May 1, 2012

Frankfurt J, Duncan A, Heyne R, Rosenfeld, CR. Growth Patterns in Preterm Very-Low-

Birth-Weight (PT-VLBW) Infants at 1-3yrs Correlate with Elevated Serum Leptin.

Platform Presentation at CTSA- Consortium-Child Health Oversight Committee in

Boston, Massachusetts, April 27, 2012

Jeyaraj J, Liao J,Cheong N, Savani RS. RHAMM Knockout Mice Have Delayed

Alveolarization, Have Worse Phenotype in Hyperoxia, and Do Not Increase

Alveolarization in Response to Exogenous VEGF. Platform presentation at PAS, Boston,

MA, 4/29/2012

Lal V, Persad EA, Xu H, Schwarz MA. Administration of Endothelial Monocyte

Activating Polypeptide (EMAP II) function blocking Antibody rescues alveolarization

and reduces cellular proliferation in Broncho Pulmonary Dysplasia (BPD) – Platform

presentation at AAP National Conference and Exhibition 2012, New Orleans, LA,

October 2012


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LeVan JM, Wyckoff MH, Jaleel MA, Sanchez PJ, Ahn C, Burchfield J, Christie L, Brion

LP. Impact of initiating the NICHD Neonatal Research Network SUPPORT Trial on

management and outcomes of gestational-age matched non-participants. Platform

presentation at PAS, Boston, MA 4/28/2012

Mayor RS, Finch K, Davis K, Neinest, M, Bills J, Skiles W, KuiXie S, Hahner, L, Savani

R, Clegg, D Fetal Exposure to Maternal Diets High in Fat Increases Placental and Fetal

Inflammation Impairing Postnatal Lung Development and Function. Platform

presentation at Section on Perinatal Pediatrics, 81st Perinatal and Developmental

Medicine Symposium, Neonatal Pain, Stress and Sedation in the 21st Century, Marco

Island, Florida, November 15-18, 2012

Mikhael M, Brown LS, Rosenfeld CR. Do 1979 neutrophil reference ranges accurately

diagnose the presence or absence of early onset sepsis? Poster Presentation at AAP

National Conference and Exhibition Meeting, New Orleans, LA, October 2012

Persad E, Lal CV, Xu H, Jennings M, Savani RC, Schwarz M. Endothelial-Monocyte

Activating Polypeptide II (EMAP II) is produced by epithelial cells and macrophages in

Bronchopulmonary Dysplasia (BPD). Poster presentation at American Thoracic Society

Conference, San Francisco, CA, May 2012

Stumpf K, Sánchez P: The Conundrum of Urinary Tract Infections (UTI) among Preterm

Infants in the Neonatal Intensive Care Unit (NICU). Poster presentation at PAS, Boston,

MA, 4/28/2012

Stumpf KA, Burchfield J, Sanchez PJ. Urinary Tract Infection (UTI) among Preterm

Infants. Perinatal Developmental Medicine Symposium, AAP, Section on Perinatal

Pediatrics (SoPPe), Aspen, Colorado, 6/7/2012

2011

Afanador M, Bennett KM, Legan S, Xu H, Dravis C, Williams O, Savani RC,

Henkemeyer M, Schwarz MA. Mice lacking Ephrin B2 reverse signaling have increased

lung fibronectin deposition and compromised pulmonary function. Platform presentation

at PAS, Denver, CO, 4/30-5/2/11; PAS Travel Award

Dupont TL, Chalak LF, Morriss MC, Rollins N, Heyne R, Sánchez PJ.

Neurodevelopmental (ND) Outcomes and Brain MRI Findings in Infants Treated with

Systemic Hypothermia for Hypoxic-Ischemic Encephalopathy (HIE). Submitted to PAS-

SPR 2011

Frankfurt J, Duncan A, Heyne R, Rosenfeld CR. Studies of renal function and systolic

blood pressure in preterm very-low-birth-weight infants at 1-3 years chronologic age.

Presentation at PAS, Denver, CO, 4/30-5/2/11

Frankfurt J, Duncan A, Heyne R, Rosenfeld CR. Studies of renal function and systolic

blood pressure in preterm very-low-birth-weight infants at 1-3 years chronologic age.

Poster Presentation at 78th Perinatal & Developmental Medicine Symposium “The

Science and Practice of Protecting Newborn Lungs” Aspen, CO, June 2-5, 2011


11

Jeyaraj J, Liao J,Cheong N, Savani R: The Hyaluronan Receptor RHAMM Significantly

Contributes To Alveolarization During Normal Development and in the Response to

Neonatal Hyperoxia. Platform Presentation, AAP-South Central Conference on Perinatal

Research, Austin,TX, October 2011

Jeyaraj J, Liao J, Cheong N, Longoria C, Mirpuri J, Savani RC. The Hyaluronan

Receptor RHAMM Significantly Contributes To Alveolarization During Normal

Development and in the Response to Neonatal Hyperoxia. American Academy of

Pediatrics Section on Perinatal Pediatrics 79th Perinatal & Developmental Medicine

Symposium, Marco Island Marriott Resort, Marco Island, Florida, 11/10-13/11

Sparks JE, Jaleel MA, Christie L, Brion LP, Wyckoff, MH. Impact Of Changes In The

2006 Neonatal Resuscitation Program (NRP) Recommendations For Delivery Room

Epinephrine Use. Platform Presentation at PAS, Denver, CO, 5/1/11

Sparks JE, Chalak LF, Perlman JM, Wyckoff MH. Ergonomics of neonatal CPR: Cardiac

compressions from the patient’s side versus head of bed. Platform Presentation at PAS,

Denver, CO, 4/30-5/2/11

St.John LT, Christie LH, Burchfield J, Wyckoff MH. Effectiveness of Plastic Lined Hats

for Prevention of Hypothermia in Premature Newborns in the Delivery Room. Poster

presentation at PAS, Denver, CO, 4/30-5/2/11

St.John LT, Christie LH, Burchfield J, Chalak LF, Wyckoff MH. Admission

Hyperthermia in Preterm Newborns < 34 wks Gestation: Risk Factors and Morbidities.

Poster presentation at PAS, Denver, CO, 4/30-5/2/11

2010

Afanador M, Bennett KM, Dravis C, Henkemeyer M, Schwarz MA. Role of EphrinB2 in

Distal Pulmonary Epithelial Formation. Oral presentation at the American Academy of

Pediatrics 76th Perinatal & Developmental Medicine Symposium in Aspen, Colorado,

June 12, 2010

Afanador M, Bennett KM, Dravis C, Henkemeyer M, Schwarz MA. Role of EphrinB2 in

Distal Pulmonary Epithelial Formation. Presentation at: AAP South Central Perinatal

Conference, Austin, TX, 10/26-28/10

DuPont TL, Chalak LF, Morriss MC, Heyne R, Sánchez PJ. Short-term outcomes of

infants who did not qualify for hypothermia therapy for hypoxic ischemic

encephalopathy. Poster presentation at PAS-SPR, Vancouver, Canada, 5/10

DuPont TL, Chalak LF, Heyne R, Morriss MC, Sánchez PJ. Short-term outcomes of

infants who did not qualify for hypothermia therapy for hypoxic ischemic

encephalopathy. Presentation at: AAP South Central Perinatal Conference, Austin, TX,

10/26-28/10

Frankfurt J, Duncan A, Heyne R, DeSpain K, Rosenfeld CR. Studies of Renal Function

and Blood Pressure in Preterm Very-low-birth-weight Infants at 1-3yrs Chronologic Age.

Presentation at: AAP South Central Perinatal Conference, Austin, TX, 10/27/10


12

Kapadia VS, Chalak LF, Dupont TL, Christie L, Burchfield J, Brion LP, Wyckoff MH.

Hyperoxemia within the 1st hour of life following perinatal asphyxia and subsequent

development of moderate-severe hypoxic ischemic encephalopathy (HIE). Platform

presentation at PAS-SPR, Vancouver, Canada, 5/10

Sparks JE, Jaleel MA, Christie L, Brion LP, Wyckoff MH. Impact of Changes in the

2006 Neonatal Resuscitation Program Recommendation for Epinephrine Usage in the

Delivery Room. Oral presentation at Seventeenth Annual South Central Conference on

Perinatal Research, Austin, TX, 10/26-28/10

St.John L, Christie LH, Huan R, Wyckoff MH. Risk factors for the development of

hypothermia in preterm infants in the delivery room. Poster presentation at PAS-SPR,

Vancouver, Canada, 5/10

Sundgren NC, Mineo C, Shaul PW. C-Reactive Protein Antagonizes Endothelial NO

Synthase via FcγRI and Src Kinase-dependent Activation of FcγRIIB. Presentation at Am

Heart Association, Chicago, IL, 11/15/10

INVITED PRESENTATIONS

2012

Lal CV, Wyckoff M - NRP Current Issues Seminar- AAP National Conference and

Exhibition, New Orleans, Louisiana 10/19/12

Lal, CV. NRP Workshop - “Full Throttle NRP”. SWAN (Scott & White Annual

Neonatal) Conference, Temple, Texas 10/5/12

Stine, CN. NRP Workshop - “Full Throttle NRP”. SWAN (Scott & White Annual

Neonatal) Conference, Temple, Texas 10/5/12

2011

Sparks JE. 2010 ILCOR and NRP Guidelines Update. Presented at: Annual Respiratory

Care Symposium, Texas Society of Respiratory Care, Plano, TX, 4/15/11

2010

Sparks JE. Current Concepts in Neonatal Resuscitation. Presented at: Annual Respiratory

Care Symposium, Texas Society of Respiratory Care, Plano, TX, 4/23/10

UTSW COMMITTEES

Joseph B Cantey:

2013-2015 Parkland Memorial Hospital, Infection Prevention Committee

2013-2014 CMC Clinical practice guideline committee: Pancreatitis

Heather Weydig:

2014-15 Representative of the subspecialty trainees in the Department of Pediatrics on the

GME Residency Advisory Committee (RAC)

Lindsay DeVries

2015-16 Housestaff Wellness and Health Initiative 2015-16


13

EXTRAMURAL COMMITTEES

Joseph B Cantey:

2014-15 Society for Healthcare Epidemiology in America (SHEA) Pediatric Steering

Committee

John Sparks:

2010-present Fetus and Newborn Committee, Texas Pediatric Society

Shawndip Sen:

2014-16 District VII Fellow TECaN Representative

2014-16 Participation in the AAP Section on Young Physicians Leadership Alliance

(YPLA )

EDITORIAL RESPONSIBILITIES

Joseph B Cantey:

Contributing Editor,

Neonatal section

Board member

Nelson’s Pediatric Antimicrobial Therapy. American Academy of

Pediatrics, JS Bradley, Editor; JD Nelson, Emeritus. 20th edition to present.

Pediatric Infectious Disease Society – Publications Committee

AWARDS, HONORS AND GRANTS

Awards:

o Young Investigator Award, American Academy of Pediatrics (AAP): Reina Mayor

Maternal Diet Impairs Fetal Lung Development, 2014

o First Neonatal Cardiopulmonary Biology Young Investigators' Forum, Chicago,

September 18-21, 2014: "Top Basic Science Study Award," Charitharth Vivek Lal 2014

o Pediatric Infectious Disease Society: PIDS Antimicrobial Stewardship Award:

Joseph Cantey 2014

o Southern Society of Pediatric Research: Finalist for the Basic Science Young Investigator

Award: Lal CV 2013

o Society for Pediatric Research (SPR) and the SPR Fellow Research Award Committee:

Fellow Basic Research Award: Lal CV: for abstract “Dysplasia (BPD)-Like Phenotype

in Uninjured Mice, and Hyperoxia-Induced BPD Is Improved by an EMAP II Blocking

Antibody” 2013

o Young Investigator Award, American Academy of Pediatrics (AAP): Charitharth V. Lal.

Role of EMAP II in the pathogenesis of BPD in a neonatal mouse model. 2012

o Annual Senior Fellows’ Research Day Awards, UTSW, Department of Pediatrics:

o Sundgren N: Best Abstract and Presentation, 2011

o LeVan J: Best Poster Presentation, 2012

o Reina Mayor: Best Abstract and Presentation, 2014


14

o Selected for AAP Perinatal Section Trainee and Early Career Neonatologists Group

(TECaN) Newsflash and AAP Perinatal Trainee Website,

http://www.aap.org/sections/perinatal/TrainFeature.html (2011). Mari Afanador

o President's Presenters Award, Society for Gynecologic Investigation, sponsored by

Wyeth: LaKeitha Foster. Maternal progesterone treatment retards labor in mice by

antagonizing inflammatory response pathways and SP−A secretion by the fetal lung.

2008

o Travel Awards:

o Cantey JB: PAS Travel Awards Program for Young Investigator’s 2015

o Charitharth (Vivek) Lal: PAS Travel Awards Program for Young Investigator’s

2014

o Charitharth (Vivek) Lal: AAP Neo Conference 2014

o Charitharth (Vivek) Lal: AAP (NCE SOPPe Travel Grant) 2013

o Charitharth (Vivek) Lal: American Academy of Pediatrics Travel Scholarship,

2013 Workshop on Perinatal Practice Strategies in Scottsdale, AZ, 2013

o Charitharth (Vivek) Lal: AAP (NCE SOPPe Travel Grant) 2012

o Jenitha Jeyaraj: PAS 2012

o Joshua Frankfurt: PAS Travel Award awarded by PAS CTSA Consortium- Child

Health Oversight Committee (CC-CHOC), 2012

o Mari Afanador: PAS 2011

o Vishal Kapadia: PAS 2010

o Fellows’ Section of Membership in the Society for Pediatric Research (SPR)

o Joseph B Cantey 2012

o Charitharth V Lal 2012

o Member of the Society for Pediatric Research (SPR):

o Joseph B Cantey 2012

o Accepted to the Duke MBA program, Olutoye Osunbunmi: 2013

Funding during fellowship

Name Sponsor Award/Grant Title Years

Joseph

Cantey

Gerber

Foundation

Novice

Researcher

Award ;

#5200762201

Use and Misuse of Antibiotic

Therapy in the Neonatal Intensive

Care Unit

2012-13

Christina

Stine

American

Academy of

Pediatrics

NRP Research

Grant & Young

Investigator

Award

Program

End tidal carbon dioxide (ETCO2)

prediction of return of spontaneous

circulation (ROSC) during CPR in

asystolic and bradycardic neonates

2013-14

Reina

Mayor

American

Academy of

Pediatrics

Marshall Klaus

Perinatal

Research

Award

In utero maternal high fat diet

increases fetal lung inflammation

impairing lung development

2013-14

John American NRP Research Randomized, Controlled Pilot Study 2011-12

http://www.aap.org/sections/perinatal/TrainFeature.html


15

Sparks Academy of

Pediatrics

Grant & Young

Investigator

Award

Program

of Asynchronous Compression and

Ventilation Cycles vs Standard

NRP CPR for Resuscitation in a

Neonatal Swine Asphyxia Model

Michel

Mikhael

Children's

Medical Center

Children’s

Clinical

Research

Advisory

Committee

(CCRAC)

Peri-operative Assessment of the

Hypothalamic-Pituitary-Adrenal

Axis Predicts Outcome in Neonates

Undergoing Cardiac Surgery

2011-13

Vishal

Kapadia

Children's

Medical Center

Foundation

North and

Central Texas

Clinical and

Translational

Science

Initiative

(NCTCTSI)

Pilot Grant

Award

Program

Randomized Trial of a Limited

versus Traditional Oxygen Strategy

During Resuscitation to Prevent

Oxidative Stress in Premature

Newborns

2010-11

Nathan

Sundgren

NIH Loan

Repayment

Program (LRP)

- 2010-11

Nathan

Sundgren

Children's

Medical Center

Children’s

Clinical

Research

Advisory

Committee

(CCRAC)

Role of Fc Receptors in High Fat

Diet-Induced Hypertension 2010-11

John

Sparks

Children's

Medical Center

Children’s

Clinical

Research

Advisory

Committee

(CCRAC)

Randomized Controlled Pilot Study

of Asynchronous Compression and

Ventilation Cycles vs. Standard

NRP CPR for Resuscitation in

Neonatal Swine Asphyxia Model

2010-11

Katherine

Bennett

American

Academy of

Pediatrics

Marshall Klaus

Perinatal

Research

Award

The role of Ephrin B2 reverse

signaling in lung morphogenesis 2009-10

Natalie

Frost

Ikaria Advancing

Newborn

Medicine Grant

Program

Estrogen and Estrogen Receptor

Modulation of BPD 2009-10

Lilian

St.John

American

Academy of

Pediatrics

NRP Research

Grant & Young

Investigator

Award

Program

Effectiveness of Plastic Lined Hats

for Prevention of Hypothermia in

Preterm Newborns in the Delivery

Room,

2008-10

Previous Graduates: Promotion to senior rank


16

Myra Wyckoff, M.D.: Promoted to Associate Professor July 2008

Andrea Duncan, MD: Promoted to Associated Professor June 2014

University of Texas Southwestern Clinical Research Scholar, UT Southwestern Center for

Translational Medicine and the Department of Clinical Sciences at UTSW

Lina Chalak, MD. 2007-12

Vishal Kapadia, MD. 2013-16

Selected for the SPR Young Investigator Coaching Program

Vishal Kapadia, MD, 2014; mentor: Ola D. Saugstag, MD.

Grants obtained by graduates

Name Sponsor Support

years

Title Amount

Kapadia (PI:

Robert Toto)

Center for

Translational

Medicine at

UTSW

KL2TR001103

2013-2015 NIH/NCATS, KL2 Award $90,000

Kapadia (PI) American

Academy of

Pediatrics/AHA

NRP Research

Award

2014 Novel Transitional Goal

Saturations for Preterm

Resuscitation in the Delivery

Room: A Randomized

Control Trial

$50,000

Chalak (PI) NIH-National

Institutes of

Health K23

HD069521

7/1/12 –

6/30/15

Cerebrovascular Dysfunction

with HIE During

Hypothermia and Rewarming

$350,525

Chalak (PI) Gerber

Foundation

11PH-011-1302-

2996-01

1/1/2012-

12/31/2014

Rewarming Phase of

Hypothermia Therapy to

Optimize Outcomes in

Hypoxic-ischemic

Encephalopathy

$120,545

Chalak (PI) Gerber

Foundation

11/17/2011-

10/16/2013

Rewarming Phase of

Hypothermia Therapy to

Optimize Outcomes in

Hypoxic-ischemic

Encephalopathy

$131,604

Chalak (PI) NIH-National

Institutes of

Health 1 RO1

MH092535-02

9/15/11 –

5/31/15

Structural development of

human fetal brain

$267,538

Wyckoff (PI) Ikaria

Investigator

Initiated Grant

Nov 2010-

Nov 2012

Inhaled NO in neonatal

asphyxia

$119,492

Wyckoff (Site

PI)

NICHD

Cooperative

Multicenter

NRN: 8 U10

4/1/2014 -

3/31/2016

- $1,000,000

(2011-16)


17

HD040689-12

Chalak (PI) North and

Central Texas

Clinical and

Translational

Science

Initiative

(NCTCTSI)

Pilot Grant

Award Program

2010-2011 Optimizing Hypothermia

Therapy: A Pilot Study for

Evaluation of the Rewarming

Phase in Newborns with

Hypoxic-Ischemic

Encephalopathy (HIE)

$39,970

Vyas-Reed

Shilpa (PI)

KO8 8/1/2010 -

5/31/2015

The role of reactive

oxygen species in alveolar

epithelial-mesenchymal

transition

$127,850

Wyckoff (PI)

AAP, Neonatal

Resuscitation

Program

2008-2009 The ergonomics of neonatal

cardiac compressions

$71,030

Chalak (Packer -

PI)

NIH/NCRR 9/17/07-

5/31/12

5 KL2 RR024983-02; North

and Central Texas Clinical

and Translational Science

Initiative

$50,000

Wyckoff

(Collab.)

Idris (PI)

NIH

2004-

2009

Clinical Research

Consortium to Improve

Resuscitation Outcomes

$2,443,349

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