US Environmental Protection Agency Office of Pesticide Programs

Petition for Etoxazole -Tab E - Reduced Risk Petition/ OP Replacement Petition MRID 45630502 -Secure Miticide Reduced Risk Petition

August 11 , 2010

••

SECURE Miticidr RtdueN Risk Petitio.: Page SI

, I i

I • ~ I • ••, J L;

1 ..; •

• , !

••, !

I I i ~ ~ . -

-t

Page 80of219

SECURE Mitiddt R.cd a ~.!.d Rill.; Prti tio tl

HIl,

~

i f-'1'tt--+1f-t1++++H+-+++t++-H++-~ ! f I ~~ F. !

!

-••f

I j ! i I,g I! , ~

;1 i

Page 81 of 219

SECURE Miticidt R~ ueed Risk Petitillo _ Pagt 53

i I,

I i H I!

I i I! !lll!

-"••t

I

III !I q ! I " s u••

Page 82 of 219

SECUR!:. Mllkidc Reduced Rilk PrtillMl p~

,•I

11 I

1m ~ :~j;

d ~ I • • II! ,

I t I• .. •P f I ! ­ - • I•

~ n , • to• • •• , •- " > > >.. ,

! ! I J ~ I ! I ,.. ; ~ >­ A , • ;a, > •

I

I

-•. !

!

tl .~ ,.; ~_. , ~. . . . ~. " 0 •

-s

Pal1e 83 of 219

SECURE Miticide Red uc~_ ,-,P"'l i" -!l~~k· ~,!!!~c- Page SS

·0 •

i w

••<• •,••

< "

1 I ! IL­

I 05'. . ~_

I 1,

I I

~ ,

! ! ! ! i! 1 !, I

, I !

' l'l l lll1· J l . ~ n ' ! ~ Ii i

,.. { I i •, , ! J !

.!.ii l l I, i

.,•I

. .-W- -·, j!·~ .·-·.

Page 84 of 219

••

_. ,

SECURE Miticide Reduced Risk PetitioD _____-"'Paj! 56

!, ~

I I I I I I I I J I I I I I

!-'14--+--+-l--+-l-H H + -l-J+HH+- ! ,

! I ! i I

I g

, , !

I

, i

I

ll ~ :II, l

i,• -•, u ..

Page- 85 of 2 19

SECURE Mltiddr Reduced RioIk Petitio n Pagr 57

, e l w

•2 s •w£•

, 1 I I I

i i ! i

I

I ! I I Ii I..

l

Page 86 of 219

••

SECljRE Mkicidt R~ .ttd Risk retition Page 53

!, ~

'!; ~ t•! < !•I, ! ,•

h t 1

I I

,i

• ~

•it ,,iI

, i,I • II !

I": 1 III(\)-, ,

!j ~;

: I I!,I m tH ~ .•

-!

PagE' 87 01219

SEClJR£ Mitidde Reduced Illik retitioR rage 59

APPENDIX n- PROPOSED PRODUCT LABEL

Page 88 01219

SECURE Miticide B.tdQctd RiskPetition Psge 60

SECURETMMiticide

Active Ingredient "Etoxazole Other lngedient. Total

· H 2.6-difluorophe!l)'I)-4.(4-{1.I-dimethylethyl)-2-clhoxypheny!]-4,S. dihydrooxazole

By Wt. 72% 280/0

1OOIYo

KEEP OUT OF REACH OF CIDLDREN

CAUTION

SEE BELOW FOR ADDITIONAL PRECAUTIONARY STATEME!'TS

NET WEIGHT _

Page 89 of 219

S£C UJU: Mitit'ide Redacrd Risk Petitloll Pt;e61

PRECAUTIONARY STATEMENTS HAZARDS TO HUMANS & DOMESTIC ANIMALS

CAUTI ON Causes moderate eye irritation. Avoid contact with eyes, skinaDd clothing. Avoid breathing dust

FIRST AID,IU iDeyes: • Hold eye opell end rinse slowly and gently ..ith wa1CT for 15-20 J::linutes.

o Remnve c:onaa lenses., if presco:. afler the first j mim.~ thea c:ominue rinsing

""Call. a DOtsOn c:ootro eearer (If" doctor fi .t .vice. · oc"""""" IfOG I k i ll or oTake offcontaminated clodililg. d otll lDg: • Rinse skin immediately ~itb plentyof WB1cr for 15-20 minutes. I

• Call a ec tsce control center Of doctorfor treatnlenl advice. lf S",. Uowt<!: • Call a poisoo control center or doctor itnmediAtely for treatmentadvice.

• Han! person sip a glass of water ifable 10 s....aljcw. oDo 0 0 1 induce vomiting unless told to do so b)' I poison control center or doctor. oDo 001 eivc IlIIvthinE! ~ m~utb to an unconscious person.

U lab.led: oMove person to fresh air. olfpenoo is not breathing. call 9 11 (u n ambulance. then give artifici:it resp intion, prlerably by mou'.b-to-mcMJth, if possible. oCall . po isoo comrol eeee- or dcx:to:'" for furthrr treatment advice.

HOT LI NE NUMBER H.a\'e the producl con::aillCJ or label 'lrim you ~'ben calq. peisce cootrol caller or doctor, or 80m!: for tt'eI~ You tn4JY also contact 1-800-892-0099 for !:nJc:rEeOCV medical treatment inforrr.ation.

PERSONAL PROTECTIVE EQUIPMEIIo. (PPE): Applicators n d otber bandl~ IInlSI lJelr. long-sleeved shirl and long r ants, \IIIUerproof gloves, and socb plus shoes.

FoIJO\\' manurneturer' s instructioos for cleaning/maintaining PPE. If no such instructions for waWNes 10<:

detereeat and hot water. Keel)and wash PPE sccaretejv from other laundrv.

USER SAFETY RECOMMENDAnONS Users should: Wash hands beforeeating, drin1:ing. cbe\\ing gum.usin; 1Ob3=o or usingthe toilet. neeeve clothing immediately ifpesticidegels imMie. Thm wash thoroughly and put OIl d ean c : .-:j i~

Remove PPE immediatelyzfter hmd.lingthis product. Wash the olJtSide of gklves before temO\·ing. AJ soon u possib~ washthDroughly and change imo eleee clothIng.

ENVIRONMENTAL HAZARDS: Donot apply directly 10 water, or to areas where surface water is present or to intertidal areas bel ow the mean high water mark . Do not contaminate water when cleaning equipment or disposing of equipment wasbwaters.

Page 90 of 219

SECURE M iticide Red uced Risk Petition Plge 62

DIRECTIONS FOR USE It is a vio lat ion ofFederal Law to use this product in a manner inconsistent with its labeling.

READ ENTIRE LABEL. USE STRICTLY IN ACCORDANCE WIlli PRECAUTIONARY STATEMENTS ~'ID DIRECTIONS, AND WI11I APPLICABLE STATE AND FEDERAL REGULATIONS.

Do not apply thi s product in a way th at will contact workers or other persons, either direct ly or through drift . Only protected handlers may be in the area during applicat ion. For any requirements spec ific to your State or Tribe.consult the agency responsible for pesticide regulation.

AGRICULTIJRAL USE REQUIREMENTS Use this product only in accordance with its labeling and wi th the Worker Protection Stan dard, 40 CFR part 170. Thi s Standard contai ns requirements for the pro tection of agricultural workers on farms. forests. nurseries. and greenhouses. and handlers of agricultural pesticides. It contains requirements for training, decontam ination, notificatio n, and emergency as sistan ce. It also contains specific equipment (PPE) , and restricted-entry interval. The req uirements in this box only apply to uses of this product that are covered by the Worker Protection Standard.

Do no l enter or allow Vom er entry into tr eated erees during the restricted entry interval (REI) of 12 hours.

PPE requited for early entry 10 treated areas that is permitted under the Worker Protecti on Standard and that involves contact with anything that has bee n treated, such lIS plants, soil, or water is: Lone-sl eeved shirl and Jcng-paats, watemroof gloves. and shoes DIllS soc ks .

Page 91 of 219

SECURE Mitirid ~

~~uc rd Risk Petition Page 6:t

"tsOAI\n:a.. IUSIo:S OF USING TH!S PRODt'CT, LnDTm 1\'AJUlAN"n'

.4.."1) U \UTATIai Of U4I TUTl "

LW'ORT4"lT; Rnod U. n:Iir'r I...ahdadoo4alr. r:biIll6tdIDIler. JI.iIksrS1JIiIcM 1'rodKt, I..iaolIlC: ....--ty. arlI ~ttI~ bdcn eiq ftil pl'Oltan. lf lbr _ an _ »tttpaWc nlEN PO NOT 1.'SET1f.[ PROOl.'CT; dIn". MII~ at.1IllplWd prod.. ...tmm L5d.,-. III pan... for • nfnd ollllc ,.-ekuc: priee.

ilJSXS or USINGn ns PROCUCT Tho: ~ -.d U.... ' rctc:md 10~)' hm:1Jl • "B~) ol llllS pI'Olb:tJhoIId b: _ ttta lb::ft IJC irlheft:m ~ ri. b _ d ...iIh the.. cltha 1Woducl1lltlidl .... mpouiblt kl diminMc 1bcx risl::s illcIlJlk. buT. a'C mt llll'.md 1ll, IqIW)" 10p!Irm nI atJClI to wIuclllh& pnduc:t • "'A'ld.lKk of RnmI oltll:: I&'zel pest- rr -..:10 , raisualol: cl lb::l:!Ir(l:l pat u weedslila prodl4 illi.-,. ra!5JeCl b,-mill. m.:I Kljury III l"CUlional aop; =-lJJed b)' carT)'O"U i11 1be JDiI Sum ri1b of eropillLa'Y. ~oe , m; istInc:c u alber1lMIIaldtd ~~ ~lc llnlI lIW)' rault because or l uctl f~ 15~, '0:1QllX1iliolll. d_c, mols1Un' CllIldJliaIs, iniplioII pnaiocI, aJDdnir.,. of the ~ • !he ~ of IlpplIatiorl, prese!lCl' of 0UJcr m.amsls cillx=" IfI'Pticd in !belQ,1IU witb thil ~ 01 pOor klllflPlic:dion of pmducl. CUftn! ~ or__<.'L _ or ~m. (or. tm'l 'lrnlllol c llldl fdn) " of wllidl a"t facran bc)'CIII4lbcOCllllJlll orV The B"!'Cl" dniId be....-anhllI1cx --.c riIbIOcd nib -,- n:duor th: t.YCSbI YJdd oflhc Cfllp ill. or• ptIItft of tar #UlItd~ or ~ dea ,.., aop sud! U IddrlioIIII c.R. IIaIl'lCl"I IlIlI ~ Jl'C ~ 10" Ill: 1:fllII1O___ If lb::!:\I"I:t chooM:s "1O~ Il-= reb. 1HDl ilUS PRODUCT SHOU.D NOT BE APPUED. 8l-~.. " ~ ~~ zo:[ .,.;:qIII 0.-~ 1Kl..~ riIb AND,.t,(JR£ES lH4T All. stJO-I RISl:S A5SOClA.lFD WJIlf ntE APPUCATlC»ol AJo.1) USEAll ASSIJ)r,E) BYTIlE st·...a

v-..r. WIaII _ be IC$pOill illlc fur ~ Ill' ~ tildocllnc. tu ..~1D, ..or)idd,mcrt:eed apcmes o! ImIlq Ille CIUjl or SlIdl D:idc:QI.. ~ .. 1fICQJI ........ .-y bcdlilMoS) _'*-II!Ilmt .. 01..~ • ..,__.. farthm" Wd 8a:ft:r _ aI ristI ~ \IridI die_ d .. JnllIDcl ill .., _ 01 Iallb ~ IlllI. spcWicIIl)o Maod err.,r~ gn ~ label

Lf'm'm WAJlRAA,..," vtblt ..."ETJlltI OllIytbal ibis rroclucl COIlformsttl lhc ch=mteal ~ gn tw: lCIclllll<l is ~Iy enbOle fl'IlJ'C-CS ~ in Ol: IaXl, weier ...aIIF lac ~ whclllI50d rIridI)."is IaXI'llInlz willi dlr; Ioild ..tlllUbjtd to ~ Risks or tailq: T1liI Pftld.d u dnr:rtbed abou. £XCEPT AS SI:T FORnI ABO\'I., \ '.4l.E1\IT MAICESNO O'nIDl WA.RJVJllTIIS, EI11llJt EXPRESSED OR L'olJ'UE1)"No J@II'lll Of~.. ot Valo:nl .. ~r!llol" io -.tbDrizc4 10mU err_ "my l:Ilhft'CllpaI orimplood~

UMl'TAn ON (W l~lUn

....nomt ...VWal errSdkr lor .blr lor .., fill, ~-.rbd. 1D4irtd or 'P'cW""'" I'tSllt!ml: rr- llot _ ..ba4.lI III n.it ~ 11lc .................. ill ..~ Ie" IIl,... ...... .-y ..... ttlllot truM ......qe. ..~ e-e, ~orodotr~~Iirtd tel tIIk Ek' g-ql ~~ cMrJ:a or.mrN '-- nlIaet. -:-..I ....... "'*-......_..., d.-..-. nu: Oa.usn"t R£MID\" OJ" na.1t.Il'tR, AND l1I£ Da.lJSl\"I !'lUL\lUM a.lUD..lTY Of VA.LL"'IT <:. SE:LLE.R FOIl A.N\"-""'D All. CLAl\tS. LOSSI:S, 1SJl.1U1S OR DA.~ (l"'lCUJl)~ .=.:.n:sJLASID ~

BRUCH Of' "'A.ItJl.A1'on".CO'01lA.Cf. NEG1.IGD'CE.TORT,SI1UCT UA.ml.nY fa OTHDlWlSE) 1IlI~I"'L" NG f'RClM 1 tIE I l SE 0& HA./\inUNG OF 1HlS PIlODllCT SHAll. B£ nlE R£n'RN OfTm P\-"JlCKA.SE P1UCE OF T1DS PRf'I'UCT OIl. "T rat EI.LC1'1ON Of \ 'A.lLNT ORSUlLR. THI RUl.r\CI:l\~TOFnII PRODUCT. I PR OM!'T Nona OJ" CLU\t.

Valent must be provided notice as soon as Buyer has reason to believe it may have a claim, tut I in no event later than twenty-one days from date of planting. or twenty-one days from the da;e I ofapplication, whichever is latter, so thaJ. an immediate inspection of the affected property 8 'lJ 1 growing crops can be made.

Jr~ dix:sIlOl IlIllif.. Vaknz O!...,. dUns • ilUCh pcrioc1 t I~ be t.red &011I ~~" ICIlCdy .

NO A.ML"\DMESn \I.... DCl Sdltr dItt lbrI J'lIt'h:I, It< ~ a;o;:qG iL Sllloj:c: klltlf ~DW::lencr" R* dlJl_ nus ~~ lJ:r:~ WIrnIIlY md ~ ofl.Jobilily. ......JdI JnI)" 100I: be IIlICIllffied by 11I)"cnf Ill' ..... -.=nat

NOTIa.: Tnk amq .... _ "rl"i>pndld willi ..)' . tlwr pnlCIud ..1Uc" is .Ol lp"clfitally Ull eTprcIIIy . l llIa riul! hy I1M' Il bd 11111I br tlor f l rl lUl~c risk Dr~. lppliClnor ..d!w .pp!lr.atl .... 1llvi!0J'.

Rc.Id an ~ roll!l'\\"Itlf mti:R: ltIbcl af fad> mMhocI lObe llSI::d i/lll>o W1I; rn~ ".,;t!lltlif, orodu01.

Page 92 01219

SECURE Miticide Red uced Rbk Peti tion Pstgc 64

COTTON

CROP PESTS

r -Crom Two<~ SJ'ider Mik

C_ inesJlldtr MiL: J>a:::ific Spi <let M,,~

I

i, i!, I

I

I

PRODUCT RATE I SPECIAL INSTRUcnONS OUAeRE

~- _ -

;---_ . _ ."-- ,.~ _._- - - ..• - ._ . __ . .--­0.66- 1.0 Appty withmar grouod ~ipmtal ill a&qu.ase w.a1C'r fex

uniform coverage (3 to 10 pk.Jacft' by_ Of 101010 gaIs,la..--reb) ,,"ooOOj. C~ IS alf'lllial furgood

eattroI, U5~ of hi¢le:' -=-voIlml1: oriIJ l5JIft' bettn

"""'" Besl rnuIt5 In a.d1):vcd wbal mit!: pclIlV1.ntni an: ........ SECURE ispredml~ an twieidelllrviei ~ andsMuld he ~ =rly in the IDe ~ of mileS. The P'tJdaIci should be 8f"J'\ied • 1bc tln5hokl Wr )'OIJ" .:ca SECURE i< ....: .. odulbcitlc IDd if adult Illites _ P"'SC" 1 in medium 10 IUgtI llIlIIIben. applySECURE ill COlIlbinmlln with a ~

contICf adakic:idc,

Mali:e I ~ applicllioo. if neoeaury IOmUilIinCOllJOl buI DO SOCClel"1blID ZI daysaltD-lbe b ~ Do!XlI: lBIke

_____ • _~~. ~ app!~~SCI5 on.

IDo ~ ::~ morethan :2 <u or SECUREret lK:I1: perseasoo, Do DOl Iv wil:hiJI U dlrYs ofharvcst -

MANAGING RE...~lSTANCE: Repeated use of the same class of miticides or miricides ....1th similar modes of action can lead to the buildup ofresistant mite strains. SECURE should be used in alternation with o':her miticides possessing dissimilar modes of ecticc undlor with other chemical classes of miticides. Follow local. state, Md federal IPM and Resistance Managel]ll:nt (RM) ~eommcndat.iollS- Read and follow all productl~l; J J :';)Te

applying any miticide.

Page 93 of 219

SEOJRE Mitidd~ Rt11~Ctd ~Risk PrliT:io _ Page 6S

IPESTSOPS OlJAeRE

,- ~R" t.tae 2.0 _ 1 0

• M~ Sp*" MlIe

""

-T ~d Spider Id ~ 30 PlICil'il' SpKIa MAe

I II, I

rOME FRUIT .. . .

!PRODUCT RA~ SPEClAL INSTRUCTIONS

~ II)' lIft*IlI with IirblaIl: equipaIl ... IUlirlan mso pis Ia:re ~ is ---.r h pod o:a:It'd Uk ofhiF . z:r ¥OkmK ... .-rc:

"""' ....... &sI: ~ rc: KlwoU r..m~ papWnons lIlT

.... SF.ClJREiI~.. ~

d duol6 too IlSrtl c.ty • theIih tyde (11 millS TbI: I . ~ JtnlId be IIC'Pbed lIl ltl=bald far )'CU ~

SECUP.E iI 0lIl .. ~mil If ..... _.... .

P=CII:. lIlCdiUlIl lOhiIb ~ awtY SECURE ill com~ W11t1. . rqt!lcrul ~ ad'.IIbo:ick

M:Il=l 5Ceol'lclJMlIIClllooIf ftOOl:SWy 10lllIIIlUlJl ooatrolbut 00 lOOIIer thar. 21 lbys lifter!be fnt IllPlil'lalon I.lo IlOl mate mort tltm 2 IAIlieaions ~

~

SECURE ril lllll COlIlltII RlISt~ rr 8 1is1« Mile$. It these pcsII 1ft l pttIblcu, usc., ~

DUDcMk~ f<Y I!.r ese . 1Dt>DOlll;l:' ly ~..6 oz of SEC\..'"RE po!" "":: prl" \IUICIl..

Dord m ...... ~ llr,'I (I1u­

MANAGING RES iSTANCE: Repeated useof the same class of miticidcs or mitid des with sirrilar"'tK''b of action can lead to the bui ldup of resis"".mt mite SC"ains. SECLltE sbouJd be used irl alternation with otherrnitickh pos st!>sing dissimilar modes of actioD andlor with otherc:bemical classes of mit icides. Follow local. ':1ll1t' _ d federal rPM andResistaDcc Management (RM) reccmmendatices . Read and follow all product label.!' t-e£ore applying l!IIYmilicide.

PaQe 9' of 219

--

SECURE Miticide Reduced Risk Petitio.

PESTS CROP

: 1~ed 59'*" Milt I p.:ifIc Spidtr Mit<:

!,

L IL"",........ I TnObc(! ..... 1lotJ

I 1

I

PRODUC TRATE OUACRE

2.0 - 3.0

() 66 - 1.0 +

DA>mOLO /0.21ll I&lA)

DoIlOl Ipp1yITll:Ift m..(, OZ ofS !:U JRE peren perL ---l_PO !!O..l!l1P'Y """,,in 1 4ay ofhzrTuL

Pagt 66

STRAWBERRY

SPECIAL INSTRUCTIOl'lS

IAppIy ...th Jltl'.RI tqu;rmerl! III " minirnllfl'l nf I00 plloosllil;l't ('~ lSessttrtl.b-~ cocmnl Useor bi~ ....... wQlumt wiIllt"sU!'e bentT(l(l~

BUI rt.Jult5 ~.cfritvcd ...nm mite popuIlItimI ..: Iov.. S£CURE iJ prt6ralillalely III ovieMkJIwvit,cle and &hoold be \IIICd CIriyill tbt !if: ~ of mitz:s n..: p...a.:r ~d

be ~loed III II1reoMJdfry )oor ...... SECURE ~ ftl'll ... ~ _ if....1llill::s "'" pn:stI'Il ill rntdl\lmto hi£:b numbers., IJ'M' SFCI.JRE in tt>mbinaIioon willl . ~

~~

00 _ "."n ~ "I'P!latiofts 'InItI SOCt:r:.r:. if ., ~~ is .,Qkd d..-1IppIyinrSECURE. UK IIll'Clltr mitic:idt .-.tI • das __ 1I>lldc 111 _ a.­

l"~ elMs or dlM>isIry.

00";1111*_lh:m 2 ~ IIISF.CUR.E per ~

SECURE wdI Do1. ccalJOI C-')o;JIruIe t.A_ MeCher j~~ fotltns ~ slloaId tit IIled rl OlISt::a~__

App/) ' WSl!I ~ flCll&IPI2IC=t ill ~ ...... "'adi>rIn ::oo.~ I J OQ lD )OO~)

~..mOlller~~iI __• Deeded in less !lIIlIJO days to rom?!:" "''VI

_IPM ........

Comply wid! aIlllpp1i:;:abk dircclions, nslrietY.\......... . O!I the ~!MIt1 fa.- o.tuIE!. . . ,~ .~_-1" F"

~ -1

MANAGING RESISTANCE: Repealed use ofthe same class of miticides or miticldes with similar modes ofacre:! eea teed to the buildup of m istant mit e strains. SECURE should be used in ahemIltion with oth er mitiddes possessbg dissimilar modes of action and /or v.i th other chemical classes of miticides . Follow local stare, and fedcnJ IPMand Resistance Management (RM) ~commeodatiom.. Read and follow aU prodllet la:.els before applying any mirid de.

Page 95 012 19

SECURE Miticid e Redut'ed Rhk Petitiou Pal:! 67

STORAGE AND DISPOSAL

PROIllBITIONS Do not contaminate water, food or feed by storage, disposal or cleaning of equipm ent. Ope n dumping isprohibited.

STORAGE K~ pesticide in origbal coctainer. Do not pI1 eoecemrae CR" di lute into food or drink roDtainers. StoTe in cool, dr)' piece . Do not store dihded sp:1ly.

EMERGENCY RESI"OSSE: Forhelp 'o'oith any spill. leU. m or exposun: iDvolving this m.l!eriz1, a.ll dII)" or nigh: 1·8QC)..f9200099.

PESTI CIDE DISPOSAL Wanes resWtiDg from the use of thisprodua. may be disposed of 00 site OJ' al lm appreved '\\'1ISte dispo$a.I facility.

CONTAINERDISPOSAL T~le rinse (or ~). Do not reuse container. Offer for recycling or reconditiooing. or punc~ Illld dispose of II1 a saniIary Widfill,or im::~t io n, Of, ifallowed by State and local authorities, by burning. Ifburned, stay out oh moke.

Copyright: 0 2002 by Valent U.S.A. Corporation

DANTTO~ · Reg. TM er v etem U.S.A. Corpo:<ttion SECURETlI . TM of Valmt U.SA Corporzrion - ,.Vaka1 t.:..$..\.. Ce!"J'oIntiott P.O. BaK lOtS W~ Occt. CA 9o'~.,j" _ _~lDII

MAOc .. U.S.A.

EPA R~ No. ~JO).XXX

EPA. f:sl No.

~a Qe 96 012 19

SECURE Miticide Red uced Risk Petition Page 68

APPENDIX ill - ECOLOGICAL EFFECTS COMPARATIVE RISK ASSESSMENT TABLES AIm GENEEC CALCULAnONS

Page 97 of 219

S[Cl,'RE Miticide RedtKed Risk htition Page 69

ECOLOGICAL EFFECTS COMPARATIVE RISK ASSESSME/IT

Etoxezole has been compared to eight competitive products, which have the same or similar pest spectra as etoxezole and are the active ingredients in the products found to be used in pome fruit, cotton, and strawberry agriculture . The selection of these chemicals and their relative market shares in these crops were based on marketing data from Doane Marketing Research, lnc., Richard F. Buan's publication, "Insecticide And Acaricide Usage On Tree Fruit, Vines, Citrus And Nuts", and Summary Of Pesticide Use Report Data published by the California Department Of Pesticide Regulation.

Etoxezcle is compared to eacb of these eight compounds for Estimated Environmental Concentrations (EEC) and risk. The TIer 1, screening- level assessments of risk provided here are based on environmental fate and ecological toxicity data from various sources (See References). Environmental fate data as well as maximum label rates. maximum application frequency and number of applications are tabulated by crop. The EEC's were calculated using GENEEC v. 2.0.

The ecotoxicity data is presented for all compounds by endpoint. Included .are acute toxicity to three fish and three invertebrate species (including saltwater organisms). chronic toxicity to fish and freshwater and saltwater invertebrates. acute oral LDso's and dietary LC5Q's for two avian species, and chronic (reproduction) data for two species of birds.

The screening-level risk estimatesfor aquatic organisms arc based on ~ EEC divided by the lcvesr ecotoxicity value for each ecotcxicology endpoint by crop across all compounds. Tl.e4-Deyaverage EEC was used to derive the acute RQ values; the 21 -day average EEC was used to derive ttlechronic RQ values for invertebrates; and the: 6O-day average EEC was used to derive the chro-uc KQ va'oes for fish.

The screening-level risk estimates for avian species were calculated by dividing the ~...j- residue on short rangegrass (derived from Kencga) by the lowest ecotoxicity value for each avian endpoint by crop across all compounds.

RQ values greater than one indicate high risk while values less than 0.1 indicate minimal risk.

The risk assessment for etoxazoJe in this document wasconducted to compare the risks associated with the use: of SECURE Miticide to those of the competitive products. More thorough ecological risk assessments (Tier 1 and Tier 2) for etcxazole have been conducted and art presented in Section G of the Secure Miticide tolerance petition, which has been submitted to EPA coIlCUITC:Dt1)· with this reduced-risk petition.

Page 98 01219

SECURE Miticidt Red uced RiJk Petition Pag t 70

Application Data Used to Perform GE1\"EEC Calcula tions (all va lues in ugfl; ppb)

Pome Fru its Products

ActiH~ In gredien t Cloft Dteziut Et Ol: llZOk Pyridaben Hel:)'tbillW1 Ft nbutatio-oJ:ide

La bel Name Apollo Secure Pyramite Sevey SO WP Vendex 50 WP

Mn imumAppL Rate l lbs a.iJ A\

0.25 0 .135 0.5 0.19 1.0

M . 1imuUI No. AnnLlvr.

I 2 2 , 2

# Days between aDII!.

NA 2J 30 NA 0

Cotton Products

Active Illgredient Etonzole Propargite Profeaofos Dieorol Aldil:arb

ubdName ' <CUre Comite Curecron 8E Kd thane MF Temik

16.52M:n.imum AppL Rite (1Ma.i.lA) 0.045 I., 1.0 LS

Maximum No. Aoo/)..., 2 J 5' I 2

# Days between I 2JI ec et, 7 5 NA I " -­

I Label allows 6 applications but RED Iinilis seasonal total to 5 lbs.a.i/A. 2 Label allows 20 lbs. a. iJA per applicarion butlimits seaso nal total to 33 Ibs. a.iJA

Strawberry Products

Acth'e Ingredit llt Eto:u.ro lt Huyfbiazox Feubutatin -Q.lidt Propa rgite

La bel Na mt Secure Sevey 50 WP vencex 50 WP Omne

Maximum AppL. IUItt 'Ibs a. iotA" M axim um No. ADoLlvr. #I Days be tweee

." L

0.135

2

"

0.19

I

NA

, LS

3

0

1.92

2

2J

Page 990f2 19

SEC URE M llh:lde Reduced RI.k Petition . .. _ _ _ PA!c.Il . ~_.- ._. --_. ,--_._--~--_ . _-- ._--- -_._- •. .. _---_._ •.

F.n"ironrnen t.1Data U' t'd (0 Perferm GENEEC C.lculation.

I 8 a ~ ~

Active lngredle nt Cl o f~ n l e 7, i n e Etoxllzolc Pyridaben HerythillZOJI. Penbutatin Ox' Pr op llrgilcl Profenofos Oicofo!' Aldicarb

Koc 11,00 0 111S0l NA' 620 0 2300 2963 84O 5868 '0 Soil aerobi c m etab oll ~m

«(1/1) (days) '6 28' <2 1 " > 180 '0' R 43 .\0

Welled in ? No No No No No No No No No

Incorp nflllion de pth ( in.) ° ° ° 0 0 ° ° ° 2

Ai'T'liclllion Method Ground Ord &. AIr' Groun d AI' Air6 Ground GrOWld Air Ground

WaleT S " lubility (pH 7Xppm)

1.00 0.070 0,012 O . O ~ 0.0 13 0.62 28 1.32 '000

Aerobic aquatic metabolism (tlil)(da3'!) - . . . - ' 14 . . .

Hydr ol )'ll i ~ ((l ,n){dllys)(pH 7) 1.43 16' Stab le SUlble Sll blc H ·7S 14.6 2.7 Sl.Ilblc

Aquooua PhOlOlysis ((Ilf,l)(days) <7 17.4 0.02 16.6 >100 140 . 1O

. 11.9

JValues for this producttaken from Rercgiltrallon Elig.{biJil)' Documeot (RED) ' Mean of I values, BOiling from 49 101('0 35.273 ] Dati nol aveuabte-use 49 10 (minimum Kee for eloll.81.l,lle) for cr rmparlarmpurposes 4E PA 1-/" 51on R....IUC5 'Aerial.ppHuUon 01etoxazc le " !;r\,iltd In ~olt"n ·Requ;res 123 ft. buffer

SECL1lE Mitlcidt RtclltCfll Ritk Petition p, 72

Summar).. of Aquatic Estimated Environmeata! Ccncentranons

(EEC' s, expressed in ppb)

Pome Fruits I'roduds

At tive Illgrmital Oofelltaiat Etourolr ~Tida btll H n ytbiazo l Fnlbntatill-<tlidt

4-[by Avt rag t l 1.23 2.68 528 3.03 13.0

11-DlIYAvrl'll,l:: r1 027 2..5 8 1.49 3.02 13.0

6O-I>-y A' ien lr) 0.10 2.36 0.52 3.00 13.0

Certen Prod ucts

Active IDgndicDt Etoiluolr P ro p llrzile p rofe:ooros Dieofol Akfic:arb

4-Day A v~ge l 0.924 SO .06 55.39 12.62­ 9S3

:11 -0.,. Averagr1 0.1!9 16.05 38 .49 3.73 ." 6O-Dsy Avtr1l&e' 0.1 14 67 .13 2{J.1I 1.31 04'

StrawberTy Products

Act ive IacrcdicDt EtOilaz,ole lI e ~"t hiazc)1 Feabuta tl u-(I"S lde I' ro pal'J: i t~ I

4-D. )' AV..r1Itl ' 2.51 3.03 13.0 63.6 J 21 -Day Avrragt 2 2.4 1 3.02 13.0 60.4 i .66-Day Aventre' 2.2] 3 .00 13.0 53.9

• J•

I Usrd for calcularion ofaatte riskquotients

2 Used for calculation. of chronic: risl: quotieou fot" iznatcbnttes, • Used for cakulatioo ofchronic rW; qtIotieDts for fisb

p~ 101 of 219

SECURE Miticide ~cdU«d Rbk~·~P" " ~,-~~'~·,. PaJ:!.fl.

GEI\EEC Simulation - Ooftn tezinr OD r ome Fruit

~UN No . 1 roR Cl ofen~ e z ine 0" PC::l0 Fr u i t • IN P:JT VALtitS •

R.t.TE: ( II/A::;) NO. APPS " eon, SOLUBl L ,t..PPL TYPE: no- SP AA::' I NCO,, ? ONE {HUl.1 l I1J7ERVl.l. Koc (PPM I (iCRl n l 1F7 1 (1 }\ 1

. 2 ~ C ( . 250 l 1 :lOOC' . O 1 . 0 ORe RAR( S. 7 ) . 0 . 0

FI ELD AND S1ASDAF..D PONe HAI.FL I FE \'A!.C£ S (OhYS )

METABO~ I C DAYS UN:! L P.YDROL~S: S PE~LYS I S ~ErABO~I C ~I NED

I F! ELDl Rh I K/ RUllOf"F" : POl: Q) (PCND- EFFI {POND: (PONO:

,5 6 . 00 1. 43 7 . 00 - 869 . 00 . 0 0 1. 43

GENE.R I C EEC :5 lI N HI CROOMHS /LITE.R (PP3 1)

Pr.AJ( !".AX .(; CAY MAX 21 JAY MAX 60 DAY MAX 90 DAY GEEC AVG GEEC AVG GEEC AVG GEEC AVG GEEC

2 . 7 S 1.23 . 21 . 10 .o.

GENEEC Simulation - Etonzolr on Pcme Fruit

RUN No . 1 FOR SECURE 0" POI-:E FRUI T • r Nr UT VALUES

RATE ( . / ACj "o .A PPS s SOIL SOLU ~; L AP PL TYPE NO- S PRh::' !~ODR P

ONE (MUl.'r ) I NTERVAL. x oc ( PP3 J (\ CRI M l ( f":' ) ( I N)

. 135 ( . 215) 2 21 171 5C. 0 70 . 0 ORCRAR! 9.7 ) . 0 . 0

fI ELD AIID STAf.;:lARD P:lND HAl.FLI FE VALe t S ( DAYS )

METABOLIC C~YS UNT I L HYDROLYS I S ? HOTOLYS I S METABOLIC COM},J.l. i..L ( r rE~D ) RAI N/R UNOFF (POND ) I PO~D-Er r } (POND) l pnN ~)

26 . 00 2 161 . 00 ~7. 4 0 - 2 15 7 . 60 . 00 14 9.ez

GF.l\ F.RI C EE:Cs ( I l\ MI CR:>GRA.....sfl,ITER {FE'S) i

Pr.AJ( }',)J{ ~ :)F.Y "'.AX 21 DAY ~..;x 60 OAY MAX 90 DAY GEE': AVG GEE: lW G GEE': h VG GEEC AVG GE:.I:C

2 .70 2.6S 2 .5& ;; . 36 2 .21

Page 102 of 21 9

SECURE Mitic ide Red uced Risk PtiltiO D Page 74

GF..l\"'EEC Simulation - Pyrldaben on PemeFruit

RUN Ko. 1 FOR Pyr-L daben ON Pcme Fr-u i.t .. INPUT VALUES ..

Rh TE {f/AC ; No.APPS & SOIL SOLUBIL AP?L 7YPE ~O- S f RAY I NCORP ONE(MUL'Tl ! };TERVAL Koc (PPS ) (t DRI FTJ (FT) (IN)

.50:J ! • 6E 6 ! 2 30 ~ 9 1 0 . C 12 .0 OReR AR ( 9 .7 ) • C .0

r :ELD AND STANDARD POND ~P~ FL I ?E VALUES (DAYS)

METABOLIC DAYS m_TI L ~ YD ROLY SIS PHOTOLYSIS ~TABOL IC CO~E I NED

(F I ELD) RAI N/ RUNOFF (FOND) (POND-EF F) l PONJ) (PONDl

21 .00 2 N I l< .02 - 2 . 48 . 0 0 2. 48

GENERIC EEes (I N P.ICROGRAMS/LI TER (PPE»)

PEAK MAX <1 DAY MAX 21 OAY MAX 60 DAY !"tAX 90 DAY GEEC AVG GEEC AVG GEEC AVG GE£C AVG GEEC

8 . 76 5.28 1. 49 .52 . 35

GENEEC Simulation - Hcx)"thiazox aD Pome Fruit

RUN No. 1 FOR Hexyt hia zox ON Fame f'r ui t .. I NPUT VALUES ..

RArE ( I/.Il.C) No . APPS & 50: L 50LUB1L APPL TYPE NO- SPRAY I ~CORP

ONE (MUl.TI INTERV,l:o.L Kac (FFB) (t DRTF"r) (FT) (m )

. 1 9D ( .1 901 1 1 E20 0.C . 0 .0

f'I ELD AND STAI"OARD FOND HALPL: FE VALUES (DAYS)

~£TABOLI C DAYS UNT I L HYO~OLYS I S PHOTOLYS I S ~ETl\BO L I C COMB1"ED (fI ELC) RA IN/ RONOFf' (POND) (PONO-Er n (POND ) {POND:

35 .CO 2 N/ A 16 .60- 2 0 5 8. 40 . 00

GENERI C EE: s (IN MICRO GRP~S /~:TER (PPB) )

'fJIK MAX ~ DAY MAX 21 DAY 1'JJl.X 60 Ok )' MAA 90 DAY GEEC AVG GEEC AVG GEEC AVG GEEC AVG GEEC

3.03 3 .02 3 .00 2 . 99

Pa;je 103 01219

SECURE Miticide Reduced Risk Petition PlIge 75

GENEEC Simulation - Fenbutatin-oxide on Pome Fruit

RUN No . 1 FOR fenbut ~ tin ox~d e ON Pome Fr ui t ~ INFUT VALUES ~

RATE ( i/AC) No .APPS /; SOIL SOLJ BI L AFPL 7YPE No- S PF~Y I N:O R~

ON E( M~LT} INTERVAL xcc (P PE 1 (It ORI FT ) (FT) (I N)

1.000 ( 2 . 0 00 ) 2 o 2300.0 . 0

FI EL) AN' S TAN Dk~D POND HALFLI FE VALUES (DAYS)

METABOl.IC DAYS UNTIL }i YCROLYSIS FHOTOL~SI S ME~ARCL I C COMBI NED (FI ELD) RAIN/RUNOFF ( PON~) (POND- Ern (PONC) (POND)

.. ... .. .. ~1 80 . 00 2 "fA 1 00 . 0 0 - 12400. 00 . 00

GEN£RI C E EC ~ (IN ~ I CROG~Y,S/L I T E R (PPB))

PEAK GEEC

MAX AVG

... DAY GEEC

MAX 2 1 DAY AVG GEEC

!-"AX 60 DAY AVG GEEC

MAX SO DAY A.VG GEE:C

13. 00 13 . 00 13. 00 13 . 00 13 .0C

GENEEC Simulation - Etexazole on Cotton

RUN No. 1 FOR SECURE ON COTTON .. I NPUT VALUES ..

AA':'E l i lAC ) No . A PPS .. SOI L SOLUBI L APPL TYPE NO- SPRAY INCORF ONE (Me LT) I NTERVAL xc c (PFB ) ('b DRI :!) 1FT } (I N)

.045 ( .072 ) 2 21 171 50 . 0 . 0 . 0

FIELD AND STA."<DARD POND HALFLI FE VALUES {DAYS )

METr~OLIC DAYS U~ T IL HYDROLYSI S PHOTOLYSI S ME: ABOLI C COM3 I N~D

(FI ELD) RAIN /RL~OFr (POND ) (POND- trF ) ( POND) (POND)

26 . 00 2 161.00 17 .4 0- .t.l 57.60 . 00 H 9 . E2

GENERIC t Ees (I N K~~OGRk~S / LI TE R (FPTr)l

FEAK W'-X 4 DAY MAX 21 DAY MAX 60 DAY !-'.AX 90 CAY GEE::: PNG GE.EC lWG GEEC lWG GEEC AVG GE£C

932 .7 2 92 L 15 8BS .B~ 762. 90

Page 104 of 219