Urine sample-derived human induced pluripotent stem cells as a model to study PCSK9-mediated...

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Page 1: Urine sample-derived human induced pluripotent stem cells as a model to study PCSK9-mediated autosomal dominant hypercholesterolemia

Induced pluripotent stem (iPS) cells Patient-Specific Pluripotent Stem Cells.

Induced pluripotent stem (iPS) cells Patient-Specific Pluripotent Stem Cells.

RNAi Therapeutics Targeting PCSK9 for LDLc Lowering in ... · RNAi Therapeutics Targeting PCSK9 for LDLc Lowering in Hypercholesterolemia M. D. Frank-Kamenetsky1, T. Racie1, A. Akinc1,

RNAi Therapeutics Targeting PCSK9 for LDLc Lowering in ... · RNAi Therapeutics Targeting PCSK9 for LDLc Lowering in Hypercholesterolemia M. D. Frank-Kamenetsky1, T. Racie1, A. Akinc1,

Further cardiovascular OUtcomes Research with PCSK9 ...clinicaltrialresults.org/Slides/ACC2017/Fourier_Sabatine.pdf · Further cardiovascular OUtcomes Research with PCSK9 Inhibition

Further cardiovascular OUtcomes Research with PCSK9 ...clinicaltrialresults.org/Slides/ACC2017/Fourier_Sabatine.pdf · Further cardiovascular OUtcomes Research with PCSK9 Inhibition

2012/11 - IR - PCSK9

2012/11 - IR - PCSK9

Alfalfa & hypercholesterolemia

Alfalfa & hypercholesterolemia

PCSK9 Inhibition : From Genetics to Patients · PCSK9 mutations and impact on LDL-C\爀屲 PCSK9 mutations represent the major source of variability in PCSK9 expression. Two type\൳

PCSK9 Inhibition : From Genetics to Patients · PCSK9 mutations and impact on LDL-C\爀屲 PCSK9 mutations represent the major source of variability in PCSK9 expression. Two type\൳

IDENTIFICATION OF INHIBITORS FOR PCSK9

IDENTIFICATION OF INHIBITORS FOR PCSK9

Novel Therapeutic Target of PCSK9

Novel Therapeutic Target of PCSK9

Hypercholesterolemia Case Presentation

Hypercholesterolemia Case Presentation

Familial hypercholesterolemia, PCSK9 inhibition, and other .../media/Non-Clinical/Files-PDFs... · ApoC-III ANGPTL3 ANGPTL4 ApoA-V . Blood biomarkers that predict risk of and are

Familial hypercholesterolemia, PCSK9 inhibition, and other .../media/Non-Clinical/Files-PDFs... · ApoC-III ANGPTL3 ANGPTL4 ApoA-V . Blood biomarkers that predict risk of and are

PCSK9 Inhibitors - Praluent (Alirocumab) and Repatha ...€¦ · PCSK9 Inhibitors Praluent (Alirocumab) and Repatha (Evolocumab) For the Treatment of Familial Hypercholesterolemia

PCSK9 Inhibitors - Praluent (Alirocumab) and Repatha ...€¦ · PCSK9 Inhibitors Praluent (Alirocumab) and Repatha (Evolocumab) For the Treatment of Familial Hypercholesterolemia

Naturally Occurring PCSK9 Inhibitors - unimi.it

Naturally Occurring PCSK9 Inhibitors - unimi.it

The Hypercholesterolemia-Risk Gene SORT1 Facilitates PCSK9 Secretion Camilla Gustafsen, Mads Kjolby, Mette Nyegaard, Manuel Mattheisen, Jesper Lundhede,

The Hypercholesterolemia-Risk Gene SORT1 Facilitates PCSK9 Secretion Camilla Gustafsen, Mads Kjolby, Mette Nyegaard, Manuel Mattheisen, Jesper Lundhede,

Familial Hypercholesterolemia

Familial Hypercholesterolemia

Hypercholesterolemia and microvascular dysfunction: interventional ...

Hypercholesterolemia and microvascular dysfunction: interventional ...

Hypercholesterolemia Increases Endothelial Superoxide ... · Numerous disease processes, including hypercholesterolemia ( 1), atherosclerosis(2),ischemiaandreperfusion(3),acuteor

Hypercholesterolemia Increases Endothelial Superoxide ... · Numerous disease processes, including hypercholesterolemia ( 1), atherosclerosis(2),ischemiaandreperfusion(3),acuteor

Update on PCSK9 Inhibitors

Update on PCSK9 Inhibitors

Urine-sample-derived human induced pluripotent stem cells as a … · urine-sample-derived human induced pluripotent stem cells (UhiPSCs) as an appropriate tool to model PCSK9-mediated

Urine-sample-derived human induced pluripotent stem cells as a … · urine-sample-derived human induced pluripotent stem cells (UhiPSCs) as an appropriate tool to model PCSK9-mediated

PCSK9...Bryan Heart Fall Conference 2015 PCSK9 Inhibitors Current Status Title Microsoft PowerPoint - PCSK9.pptx Author tlw011 Created Date 9/2/2015 3:31:45 PM ...

PCSK9...Bryan Heart Fall Conference 2015 PCSK9 Inhibitors Current Status Title Microsoft PowerPoint - PCSK9.pptx Author tlw011 Created Date 9/2/2015 3:31:45 PM ...

Cardiovascular Franchise: Multiple Approaches to ...€¦ · Targeting PCSK9 for Lipid Management PCSK9 mRNA Reduction Correlates with LDL-C Lowering in Preclinical Studies PCSK9

Cardiovascular Franchise: Multiple Approaches to ...€¦ · Targeting PCSK9 for Lipid Management PCSK9 mRNA Reduction Correlates with LDL-C Lowering in Preclinical Studies PCSK9