Upper GI Stenting GI cancer... · 2016. 11. 17. · Owen Dickinson Consultant in Endoscopy &...

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Owen Dickinson Consultant in Endoscopy & Interventional Radiology Rotherham Foundation Trust Upper GI Stenting

Transcript of Upper GI Stenting GI cancer... · 2016. 11. 17. · Owen Dickinson Consultant in Endoscopy &...

Page 1: Upper GI Stenting GI cancer... · 2016. 11. 17. · Owen Dickinson Consultant in Endoscopy & Interventional Radiology Rotherham Foundation Trust . Declaration • No source of financial

Owen Dickinson Consultant in Endoscopy & Interventional Radiology

Rotherham Foundation Trust

Upper GI Stenting

Page 2: Upper GI Stenting GI cancer... · 2016. 11. 17. · Owen Dickinson Consultant in Endoscopy & Interventional Radiology Rotherham Foundation Trust . Declaration • No source of financial

Owen Dickinson Consultant in Endoscopy & Interventional Radiology

Rotherham Foundation Trust

Page 3: Upper GI Stenting GI cancer... · 2016. 11. 17. · Owen Dickinson Consultant in Endoscopy & Interventional Radiology Rotherham Foundation Trust . Declaration • No source of financial

Declaration

• No source of financial or commercial sponsorship

Page 4: Upper GI Stenting GI cancer... · 2016. 11. 17. · Owen Dickinson Consultant in Endoscopy & Interventional Radiology Rotherham Foundation Trust . Declaration • No source of financial

Why do we stent the upper GI

tract?

• Inability to eat solids

• Inability to drink fluids

• Inability to swallow saliva

• Occasional vomiting

• Persistent vomiting

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Oesophageal stenting – when?

• Malignancy – intrinsic / extrinsic

• Refractory benign strictures

• Oesophageal perforations

1 Asymptomatic

2 Eats solids with some dysphagia

3 Eats soft or pureed food only

4 Drinks liquids only

5 Unable to swallow saliva

Page 6: Upper GI Stenting GI cancer... · 2016. 11. 17. · Owen Dickinson Consultant in Endoscopy & Interventional Radiology Rotherham Foundation Trust . Declaration • No source of financial

Indications

Oesophageal cancer

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Other indications

• Extrinsic compression eg LNs, lung cancer

• Fistula / perforation

• Benign strictures eg peptic strictures

Page 8: Upper GI Stenting GI cancer... · 2016. 11. 17. · Owen Dickinson Consultant in Endoscopy & Interventional Radiology Rotherham Foundation Trust . Declaration • No source of financial

Who stents?

Gastroenterologist or Upper GI Surgeon

Endoscopic insertion without xray

• Problems occasionally encountered

– Unable to pass the endoscope through – too tight

– May require pre-dilation ( risk of perforation )

– Unable to assess length of stricture – therefore what length stent?

– Unable to confidently manipulate guidewire through stricture

Page 9: Upper GI Stenting GI cancer... · 2016. 11. 17. · Owen Dickinson Consultant in Endoscopy & Interventional Radiology Rotherham Foundation Trust . Declaration • No source of financial

Who else stents? Interventional Radiology

Xray insertion only • No need for an endoscope

• Catheterisation of stricture is atraumatic and virtually always successful

• Position & length of stricture accurately demonstrated

• Position of guidewire tip is seen at all times

• No pre-dilatation

• Accurate stent placement

Page 10: Upper GI Stenting GI cancer... · 2016. 11. 17. · Owen Dickinson Consultant in Endoscopy & Interventional Radiology Rotherham Foundation Trust . Declaration • No source of financial

Equipment in IR

• 4Fr Headhunter catheter

• Angled Terumo wire

• Amplatz superstiff wire

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Which stent?

1 2

3

4

5

6

7

8 1 Flamingo

2 Ultraflex

3 Dua

4 Ella

5 Polyflex

6 Choo

7 Do

8 Niti-S “Double”

8

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Ultraflex

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Niti-S “Double” Stent

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Removable stents

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Process to Oesophageal

Stenting

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How I do it

• Catheterise oesophagus

with angled catheter and

hydrophilic guidewire

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Manipulate hydrophilic guidewire through stricture

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Delineate with contrast +/- air

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• Mark

• Exchange hydrophilic for stiff

guidewire

• Remove catheter

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Introduce stent Deploy

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Result

• Technical success rates

approach 100%

• Improved dysphagia score 4

(liquids only) to 2 (able to eat

most solids)

1 Asymptomatic

2 Eats solids with some dysphagia

3 Eats soft or pureed food only

4 Drinks liquids only

5 Unable to swallow saliva

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Oesophageal complications

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Complications

• Reflux

• Aspiration

• Chest pain 10%

• Food impaction 10%

• Stent migration 10%

• Ingrowth 30%

• Overgrowth 10%

• Perforation 5%

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Proximal overgrowth

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Stent migration

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Stent migration

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Stent migration 3 days later

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Tracheo-oesophageal fistula

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Jan 11

CASE

TOF

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• 51 M SCC oesophagus

• EUS & PET T3N1M1

• Chemoradiotherapy

Jan 11

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Endoscopic stent insertion

June 11 (5m)

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Sep 11 (7m) – presents with cough on swallowing

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Jan 12 (12m) – presents with dysphagia

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6 dilatations May 12 – Apr 13 (28m)

What next?

May 12 (12m) – presents with high dysphagia

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• Same evening develops marked SOB

• CTPA requested

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CASE

GSW

Page 38: Upper GI Stenting GI cancer... · 2016. 11. 17. · Owen Dickinson Consultant in Endoscopy & Interventional Radiology Rotherham Foundation Trust . Declaration • No source of financial

• 42 M

• Gunshot through neck

• Pneumocephalus; comminuted # T1 & T2 with fragments

in canal; neck haematoma; surgical emphysema &

pneumomediastinum; comminuted # left thumb

• Cardiothoracic and ENT emergency surgery for

disruption to trachea & oesophagus

• Chest drain insertion; tracheostomy; repair of trachea &

oesophagus

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Day 6

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Day 7

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Day 26

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3 months later

Page 44: Upper GI Stenting GI cancer... · 2016. 11. 17. · Owen Dickinson Consultant in Endoscopy & Interventional Radiology Rotherham Foundation Trust . Declaration • No source of financial

Gastric Outlet (GOO) Stenting

Page 45: Upper GI Stenting GI cancer... · 2016. 11. 17. · Owen Dickinson Consultant in Endoscopy & Interventional Radiology Rotherham Foundation Trust . Declaration • No source of financial

For your consideration

• Stainless steel or Nitinol

• Length

• Uncovered or covered

• Biliary stent required?

A Boston Scientific Enteral Wallstent

B Diagmed Hanaro Enteral Stent

C Taewoong Niti-S Duodenal Covered Stent

D Taewoong Niti-S Duodenal Stent

E EnterElla Stent

Page 46: Upper GI Stenting GI cancer... · 2016. 11. 17. · Owen Dickinson Consultant in Endoscopy & Interventional Radiology Rotherham Foundation Trust . Declaration • No source of financial

• Malignant “GOO”

considered a

preterminal event

• Average survival 4/12

• Persistent vomiting

• Malnutrition

• Dehydration

• Electrolyte imbalance

Gastric Outlet Score

0 No oral intake

1 Liquids only

2 Soft solids

3 Full diet

Page 47: Upper GI Stenting GI cancer... · 2016. 11. 17. · Owen Dickinson Consultant in Endoscopy & Interventional Radiology Rotherham Foundation Trust . Declaration • No source of financial

Treatment options

• Antiemetics

• Nasogastric tube

• Venting gastrostomy

• Surgical gastrojejunostomy

• Laparoscopic gastrojejunostomy

• Stenting

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Surgical gastroenterostomy

Traditional palliative treatment for malignant gastric outlet obstruction

Mortality 2-36%

• Complications 13-55%

• Delayed gastric emptying

• Longer hospital stay mean 15 days (5-80 days) Gastroduodenal Stent Placement: Current Status

Radiographics 2004

Page 49: Upper GI Stenting GI cancer... · 2016. 11. 17. · Owen Dickinson Consultant in Endoscopy & Interventional Radiology Rotherham Foundation Trust . Declaration • No source of financial

Open gastrojejunostomy vs laparoscopic

gastrojejunostomy vs endoscopic stenting in malignant

gastroduodenal obstruction

• Significant reduction in time to starting free oral fluids and light diet

Average hospital stay mean 6.3 days (2-15 days)

• Reduction in length of stay after the procedure

Average hospital Stay 24-48 hours

• Significantly more complications in patients who underwent surgical palliation

Lee,F. Abdul-Halim,R. Dickinson,O. (2016). Malignant gastroduodenal obstruction: An endoscopic approach. Gastrointestinal Intervention. (5): 105-110

Page 50: Upper GI Stenting GI cancer... · 2016. 11. 17. · Owen Dickinson Consultant in Endoscopy & Interventional Radiology Rotherham Foundation Trust . Declaration • No source of financial

Cholangiocarcinoma

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Introduce catheter

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Get through stricture

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Stiff wire in

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Antral Carcinoma

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Cannulate stricture

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Get the wire as distal as possible

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Get ready to stent

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Stent in situ

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Stent lumen expanded

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Stent blockage

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Ingrowth

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Ingrowth

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Stent Fracture

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Stent Collapse

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Summary

• Overview of indications for stenting the

upper GI tract

• Overview of the various methods and

stents used

• Overview of the problems and

complications encountered

Page 71: Upper GI Stenting GI cancer... · 2016. 11. 17. · Owen Dickinson Consultant in Endoscopy & Interventional Radiology Rotherham Foundation Trust . Declaration • No source of financial