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Medical imagingFrom Wikipedia, the free encyclopedia
This article is about imaging techniques and
modalities for the human body. For imaging of
animals in research, see Preclinical imaging.
This article needs
additional citations for verif
ication.Please help improve this article byaddingreliable references. Unsourcedmaterial may
bechallengedandremoved.(June2009)
Medical imaging is the technique and process
used to create imagesof the human body (or parts
and function thereof) for clinical purposes (medical
procedures seeking to reveal,diagnose or
examinedisease) or medical science (including the
study of normalanatomy andphysiology). Although
imaging of removed organs andtissues can be
performed for medical reasons, such procedures
are not usually referred to as medical imaging, but
rather are a part ofpathology.
As a discipline and in its widest sense, it is part
ofbiological imaging and incorporatesradiology (in
the wider sense), nuclear medicine,
investigative radiological sciences, endoscopy,
(medical) thermography, medical photography
andmicroscopy (e.g. for human pathological
investigations).
Measurement and recording techniques which arenot primarily designed to produce images, such
as electroencephalography (EEG),magnetoenceph
alography (MEG), Electrocardiography(EKG) and
others, but which produce data susceptible to be
represented as maps(i.e. containing positional
information), can be seen as forms of medical
imaging.
Contents
[hide]
1 Overview
2 Imaging technology
3 Radiography
o 3.1 Magnetic resonance imaging (MRI)
o 3.2 Nuclear medicine
3.2.1 Photoacoustic imaging
o
3.3 Breast Thermography
o 3.4 Tomography
o 3.5 Ultrasound
4 Medical imaging topics
o 4.1 Maximizing imaging procedure use
o 4.2 Creation of three-dimensional images
o 4.3 Compression of medical images
o 4.4 Non-diagnostic imaging
o
4.5 Archiving and recording
o 4.6 Open source software for medical
image analysis
o 4.7 Use in pharmaceutical clinical trials
5 See also
6 References
7 Further reading
8 External links
[edit]Overview
In the clinical context, "invisible light" medical
imaging is generally equated to radiology or
"clinical imaging" and the medical practitioner
responsible for interpreting (and sometimes
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edia.org/wiki/Radiologyhttp://en.wikipedia.org/wiki/Nuclear_medicinehttp://en.wikipedia.org/wiki/Radiological_scienceshttp://en.wikipedia.org/wiki/Endoscopyhttp://en.wikipedia.org/wiki/Thermographyhttp://en.wikipedia.org/wiki/Microscopyhttp://en.wikipedia.org/wiki/Imagehttp://en.wikipedia.org/wiki/Electroencephalographyhttp://en.wikipedia.org/wiki/Magnetoencephalographyhttp://en.wikipedia.org/wiki/Magnetoencephalographyhttp://en.wikipedia.org/wiki/Electrocardiographyhttp://en.wikipedia.org/wiki/Maphttp://en.wikipedia.org/wiki/Medical_imaginghttp://en.wikipedia.org/wiki/Medical_imaging#Overviewhttp://en.wikipedia.org/wiki/Medical_imaging#Imaging_technologyhttp://en.wikipedia.org/wiki/Medical_imaging#Radiographyhttp://en.wikipedia.org/wiki/Medical_imaging#Magnetic_resonance_imaging_.28MRI.29http://en.wikipedia.org/wiki/Medical_imaging#Nuclear_medicinehttp://en.wikipedia.org/wiki/Medical_imaging#Photoacoustic_imaginghttp://en.wikipedia.org/wiki/Medical_imaging#Breast_Thermographyhttp://en.wikipedia.org/wiki/Medical_imaging#Tomographyhttp://en.wikipedia.org/wiki/Medical_imaging#Ultrasoundhttp://en.wikipedia.org/wiki/Medical_imaging#Medical_imaging_topicshttp://en.wikipedia.org/wiki/Medical_imaging#Maximizing_imaging_procedure_usehttp://en.wikipedia.org/wiki/Medical_imaging#Creation_of_three-dimensional_imageshttp://en.wikipedia.org/wiki/Medical_imaging#Compression_of_medical_imageshttp://en.wikipedia.org/wiki/Medical_imaging#Non-diagnostic_imaginghttp://en.wikipedia.org/wiki/Medical_imaging#Archiving_and_recordinghttp://en.wikipedia.org/wiki/Medical_imaging#Open_source_software_for_medical_image_analysishttp://en.wikipedia.org/wiki/Medical_imaging#Open_source_software_for_medical_image_analysishttp://en.wikipedia.org/wiki/Medical_imaging#Use_in_pharmaceutical_clinical_trialshttp://en.wikipedia.org/wiki/Medical_imaging#See_alsohttp://en.wikipedia.org/wiki/Medical_imaging#Referenceshttp://en.wikipedia.org/wiki/Medical_imaging#Further_readinghttp://en.wikipedia.org/wiki/Medical_imaging#External_linkshttp://en.wikipedia.org/w/index.php?title=Medical_imaging&action=edit§ion=1http://en.wikipedia.org/wiki/Radiologyhttp://en.wikipedia.org/wiki/Preclinical_imaging 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acquiring) the images is a radiologist. "Visible light"
medical imaging involves digital video or still
pictures that can be seen without special
equipment. Dermatology and wound care are two
modalities that utilize visible light imagery.
Diagnostic radiographydesignates the technical
aspects of medical imaging and in particular the
acquisition of medical images.
Theradiographerorradiologic technologistis
usually responsible for acquiring medical images of
diagnostic quality, although some radiological
interventions are performed byradiologists. While
radiology is an evaluation of anatomy, nuclearmedicine provides functional assessment.
As a field of scientific investigation, medical
imaging constitutes a sub-discipline ofbiomedical
engineering, medical
physics ormedicinedepending on the context:
Research and development in the area of
instrumentation, image acquisition
(e.g. radiography), modelling and quantification are
usually the preserve ofbiomedical
engineering, medical physics and computer
science; Research into the application and
interpretation ofmedical images is usually the
preserve ofradiology and the medical sub-
discipline relevant to medical condition or area of
medical science
(neuroscience, cardiology,psychiatry,psychology,
etc.) under investigation. Many of the techniques
developed for medical imaging also
havescientific and industrial applications.
Medical imaging is often perceived to designate
the set of techniques that noninvasively produce
images of the internal aspect of the body. In this
restricted sense, medical imaging can be seen as
the solution ofmathematicalinverse problems.
This means that cause (the properties of living
tissue) is inferred from effect (the observed signal).
In the case of ultrasonography the probe consists
of ultrasonic pressure waves and echoes inside the
tissue show the internal structure. In the case of
projection radiography, the probe isX-
rayradiationwhich is absorbed at different rates in
different tissue types such as bone, muscle and
fat.
The term noninvasive is a term based on the fact
that following medical imaging modalities do not
penetrate the skin physically. But on the
electromagnetic and radiation level, they are quite
invasive. From the high energy photons in X-Ray
Computed Tomography, to the 2+ Tesla coils of an
MRI device, these modalities alter the physical and
chemical reactions of the body in order to obtain
data.
[edit]Imaging technologyThis section has no
content. You can help Wikipedia
by introducing information to
it.(October 2010)
[edit]Radiography
Main article: Medical radiography
Two forms of radiographic images are in use in
medical imaging; projection radiography andfluoroscopy, with the latter being useful for
intraoperative and catheter guidance. These 2D
techniques are still in wide use despite the
advance of 3D tomography due to the low cost,
high resolution, and depending on application,
lower radiation dosages. This imaging modality
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utilizes a wide beam ofx rays for image acquisition
and is the first imaging technique available in
modern medicine.
Fluoroscopyproduces real-time
images of internal
structures of the
body in a similar
fashion
toradiography,
but employs a
constant input of
x-rays, at a lower
dose
rate. Contrast
media, such as
barium, iodine,
and air are used
to visualize
internal organs as
they work.Fluoroscopy is
also used in
image-guided
procedures when
constant feedback
during a
procedure is
required. An
image receptor is
required to
convert the
radiation into an
image after it has
passed through
the area of
interest. Early on
this was a
fluorescing
screen, which
gave way to an
Image Amplifier
(IA) which was a
large vacuum
tube that had the
receiving end
coated
withcesiumiodide, and a
mirror at the
opposite end.
Eventually the
mirror was
replaced with a
TV camera.
Projectional
radiographs, more
commonly known
as x-rays, are
often used to
determine the
type and extent of
a fracture as well
as for detecting
pathological
changes in the
lungs. With the
use ofradio-
opaque contrast
media, such
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as barium, they
can also be used
to visualize the
structure of the
stomach and
intestines - this
can help diagnose
ulcers or certain
types ofcolon
cancer.
[edit]Magnetic resonance imaging
(MRI)
Main article: Magnetic resonance imaging
A brain MRI representation
A magnetic resonance imaging instrument (MRIscanner), or "nuclear magnetic resonance (NMR)
imaging" scanner as it was originally known, uses
powerful magnets to polarise and
excitehydrogennuclei (single proton) in water
molecules in human tissue, producing a detectable
signal which is spatially encoded, resulting in
images of the body. MRI uses
threeelectromagnetic fields: a very strong (on the
order of units ofteslas) static magnetic field to
polarize the hydrogen nuclei, called the static field;
a weaker time-varying (on the order of 1 kHz)
field(s) for spatial encoding, called the gradient
field(s); and a weak radio-frequency (RF) field for
manipulation of the hydrogen nuclei to produce
measurable signals, collected through anRF
antenna.
Like CT, MRI traditionally creates a two
dimensional image of a thin "slice" of the body and
is therefore considered atomographic imaging
technique. Modern MRI instruments are capable of
producing images in the form of 3D blocks, which
may be considered a generalisation of the single-
slice, tomographic, concept. Unlike CT, MRI does
not involve the use ofionizing radiationand is
therefore not associated with the same health
hazards. For example, because MRI has only been
in use since the early 1980s, there are no known
long-term effects of exposure to strong static fields
(this is the subject of some debate; see 'Safety'
in MRI) and therefore there is no limit to the
number of scans to which an individual can be
subjected, in contrast with X-ray and CT. However,
there are well-identified health risks associated
with tissue heating from exposure to the RF field
and the presence of implanted devices in the body,
such as pace makers. These risks are strictly
controlled as part of the design of the instrument
and the scanning protocols used.
Because CT and MRI are sensitive to different
tissue properties, the appearance of the images
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obtained with the two techniques differ markedly.
In CT, X-rays must be blocked by some form of
dense tissue to create an image, so the image
quality when looking at soft tissues will be poor. In
MRI, while any nucleus with a net nuclear spin can
be used, the proton of the hydrogen atom remains
the most widely used, especially in the clinical
setting, because it is so ubiquitous and returns a
large signal. This nucleus, present in water
molecules, allows the excellent soft-tissue contrast
achievable with MRI.
[edit]Nuclear medicine
Main article: Nuclear medicine
Nuclear medicine encompasses both diagnostic
imaging and treatment of disease, and may also be
referred to as molecular medicine or molecular
imaging & therapeutics[1]. Nuclear medicine uses
certain properties of isotopes and the energetic
particles emitted from radioactive material to
diagnose or treat various pathology. Different from
the typical concept of anatomic radiology, nuclear
medicine enables assessment of physiology. This
function-based approach to medical evaluation has
useful applications in most subspecialties, notably
oncology, neurology, and cardiology.Gamma
camerasare used in e.g. scintigraphy, SPECT and
PET to detect regions of biologic activity that may
be associated with disease. Relatively short
livedisotope, such as123Iis administered to the
patient. Isotopes are often preferentially absorbed
by biologically active tissue in the body, and can be
used to identify tumors orfracture points in bone.
Images are acquired after collimated photons are
detected by a crystal that gives off a light signal,
which is in turn amplified and converted into count
data.
Scintigraphy("sc
int") is a form ofdiagnostic test
wherein radioisoto
pesare taken
internally, for
example
intravenously or
orally. Then,
gamma camera
capture and form
two-dimensional[2]
images from the
radiation emitted
by the
radiopharmaceuti
cals.
SPECTis a 3D
tomographic
technique that
uses gamma
camera data from
many projections
and can be
reconstructed in
different planes. A
dual detector
head gamma
camera combined
with a CT
scanner, which
provides
localization of
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functional SPECT
data, is termed a
SPECT/CT
camera, and has
shown utility in
advancing the
field of molecular
imaging.In most
other medical
imaging
modalities, energy
is passed through
the body and thereaction or result
is read by
detectors. In
SPECT imaging,
the patient is
injected with a
radioisotope, most
commonly
Thallium 201TI,
Technetium
99mTC, Iodine
123I, and Gallium
68Ga [3]
. The radioactive gamma rays are emitted through
the body as the natural decaying process of these
isotopes takes place. The emissions of the gamma
rays are captured by detectors that surround the
body. This essentially means that the human is
now the source of the radioactivity, rather than the
medical imaging devices such as X-Ray, CT, or
Ultrasound.
Positron
emission
tomography(PET)
uses coincidence
detection to image
functional
processes. Short-
lived positron
emitting isotope,
such as18F, is
incorporated with
an organic
substance suchas glucose,
creating F18-
fluorodeoxyglucos
e, which can be
used as a marker
of metabolic
utilization. Images
of activity
distribution
throughout the
body can show
rapidly growing
tissue, like tumor,
metastasis, or
infection. PET
images can be
viewed incomparison
tocomputed
tomographyscans
to determine an
anatomic
correlate. Modern
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scanners combine
PET with a CT, or
even MRI, to
optimize the
image
reconstruction
involved with
positron imaging.
This is performed
on the same
equipment without
physically moving
the patient off ofthe gantry. The
resultant hybrid of
functional and
anatomic imaging
information is a
useful tool in non-
invasive diagnosis
and patient
management.
[edit]Photoacoustic imaging
Main article: Photoacoustic imaging in biomedicine
Photoacoustic imaging is a recently developed
hybrid biomedical imaging modality based on the
photoacoustic effect. It combines the advantages
of optical absorption contrast with ultrasonic spatial
resolution for deep imaging in (optical) diffusive or
quasi-diffusive regime. Recent studies have shown
that photoacoustic imaging can be used in vivo for
tumor angiogenesis monitoring, blood oxygenation
mapping, functional brain imaging, and skin
melanoma detection, etc.
[edit]Breast Thermography
It has been suggested that this
section besplitinto a new
article. (Discuss)
Digital infrared imaging thermographyis based onthe principle that metabolic activity and vascular
circulation in both pre-cancerous tissue and the
area surrounding a developing breast cancer is
almost always higher than in normal breast tissue.
Cancerous tumors require an ever-increasing
supply of nutrients and therefore increase
circulation to their cells by holding open existing
blood vessels, opening dormant vessels, and
creating new ones (neoangiogenesis). This
process frequently results in an increase in
regional surface temperatures of the breast. Digital
infrared imaging uses extremely sensitive medical
infrared cameras and sophisticated computers to
detect, analyze, and produce high-resolution
diagnostic images of these temperature variations.
Because of DII's sensitivity, these temperature
variations may be among the earliest signs ofbreast cancer and/or a pre-cancerous state of the
breast[4].
[edit]Tomography
Main article: Computed tomography
Tomographyis the method of imaging a single
plane, or slice, of an object resulting in
a tomogram. There are several forms
oftomography:
Linear
tomography: This
is the most basic
form of
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tomography. The
X-ray tube moved
from point "A" to
point "B" above
the patient, while
the cassette
holder (or
"bucky") moves
simultaneously
under the patient
from point "B" to
point "A."
The fulcrum, orpivot point, is set
to the area of
interest. In this
manner, the
points above and
below thefocal
planeare blurred
out, just as the
background is
blurred when
panning a camera
during exposure.
No longer carried
out and replaced
by computed
tomography.
Polytomography: This
was a complex
form of
tomography. With
this technique, a
number of
geometrical
movements were
programmed,
such as
hypocycloidic,
circular, figure 8,
and elliptical.
Philips Medical
Systems [1] produ
ced one such
device called the
'Polytome.' Thisunit was still in
use into the
1990s, as its
resulting images
for small or
difficult
physiology, such
as the inner ear,
was still difficult to
image with CTs at
that time. As the
resolution of CTs
got better, this
procedure was
taken over by the
CT.
Zonography:This is a variant of
linear
tomography,
where a limited
arc of movement
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is used. It is still
used in some
centres for
visualising the
kidney during an
intravenous
urogram (IVU).
Orthopantomogr
aphy (OPT or
OPG): The only
common
tomographic
examination inuse. This makes
use of a complex
movement to
allow the
radiographic
examination of the
mandible, as if it
were a flat bone.
It is often referred
to as a "Panorex",
but this is
incorrect, as it is a
trademark of a
specific company.
Computed
Tomography (CT),
or ComputedAxial Tomography
(CAT: A CT scan,
also known as
a CAT scan), is a
helical
tomography
(latest
generation), which
traditionally
produces a 2D
image of the
structures in a thin
section of the
body. It usesX-
rays. It has a
greaterionizing
radiationdose
burden thanprojection
radiography;
repeated scans
must be limited to
avoid health
effects. CT is
based on the
same principles
as X-Ray
projections but in
this case, the
patient is
enclosed in a
surrounding ring
of detectors
assigned with
500-1000scintillation
detectors[3]
. This being the fourth-generation X-Ray CT
scanner geometry. Previously in older generation
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scanners, the X-Ray beam was paired by a
translating source and detector.
[edit]Ultrasound
Main article: Medical ultrasonography
Medical ultrasonographyuses high
frequencybroadband sound waves in
the megahertz range that are reflected by tissue to
varying degrees to produce (up to 3D) images.
This is commonly associated with imaging
the fetusin pregnant women. Uses of ultrasound
are much broader, however. Other important uses
include imaging the abdominal organs, heart,
breast, muscles, tendons, arteries and veins. While
it may provide less anatomical detail than
techniques such as CT or MRI, it has several
advantages which make it ideal in numerous
situations, in particular that it studies the function of
moving structures in real-time, emits noionizing
radiation, and containsspecklethat can be used
inelastography. Ultrasound is also used as a
popular research tool for capturing raw data, that
can be made available through an Ultrasound
research interface, for the purpose of tissue
characterization and implementation of new image
processing techniques. The concepts of ultrasound
differ from other medical imaging modalities in the
fact that it is operated by the transmission and
receipt of sound waves. The high frequency sound
waves are sent into the tissue and depending on
the composition of the different tissues; the signal
will be attenuated and returned at separate
intervals. A path of reflected sound waves in a
multilayered structure can be defined by an input
acoustic impedance( Ultrasound sound wave) and
the Reflection and transmission coefficients of the
relative structures[3] . It is very safe to use and does
not appear to cause any adverse effects, although
information on this is not well documented. It is
also relatively inexpensive and quick to perform.
Ultrasound scanners can be taken to critically ill
patients in intensive care units, avoiding the
danger caused while moving the patient to the
radiology department. The real time moving image
obtained can be used to guide drainage and biopsy
procedures. Doppler capabilities on modern
scanners allow the blood flow in arteries and veins
to be assessed.
[edit]Medical imaging topics[edit]Maximizing imaging procedure
use
The amount of data obtained in a single MR or CT
scan is very extensive. Some of the data that
radiologists discard could save patients time and
money, while reducing their exposure to radiation
and risk of complications from invasive procedures.
[5]
[edit]Creation of three-dimensional
images
Recently, techniques have been developed to
enable CT, MRI and ultrasound scanning software
to produce 3D images for the physician.
[6]Traditionally CT and MRI scans produced 2D
static output on film. To produce 3D images, many
scans are made, then combined by computers to
produce a 3D model, which can then be
manipulated by the physician. 3D ultrasounds are
produced using a somewhat similar technique. In
diagnosing disease of the viscera of
abdomen,ultrasound is particularly sensitive on
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imaging of biliary tract,urinary tract and female
reproductive organs(ovary,fallopian tubes).As for
example,diagnosis of gall stone by dilatation of
common bile duct and stone in common bile duct .
With the ability to visualize important structures in
great detail, 3D visualization methods are a
valuable resource for the diagnosis and surgical
treatment of many pathologies. It was a key
resource for the famous, but ultimately
unsuccessful attempt by Singaporean surgeons to
separate Iranian twinsLadan and Laleh Bijaniin
2003. The 3D equipment was used previously for
similar operations with great success.
Other proposed or developed techniques include:
Diffuse optical
tomography
Elastography
Electrical
impedance
tomography
Optoacoustic
imaging
Ophthalmology
A-scan
B-scan
Corneal
topography
Optical
coherence
tomography
Scannin
g laser
ophthalmosco
py
Some of these techniques are still at a research
stage and not yet used in clinical routines.
[edit]Compression of medical
images
Medical imaging techniques produce very large
amounts of data, especially from CT, MRI and PET
modalities. As a result, storage and
communications of electronic image data are
prohibitive without the use of compression.JPEG
2000 is the state-of-the-art image
compressionDICOM standard for storage and
transmission of medical images. The cost and
feasibility of accessing large image data sets over
low or various bandwidths are further addressed by
use of another DICOM standard, calledJPIP, to
enable efficient streaming of theJPEG
2000 compressed image data.
[edit]Non-diagnostic imaging
Neuroimaging has also been used in experimental
circumstances to allow people (especially disabled
persons) to control outside devices, acting as
a brain computer interface.
[edit]Archiving and recording
Used primarily inultrasound imaging, capturing the
image a medical imaging device is required for
archiving and telemedicineapplications. In most
scenarios, a frame grabberis used in order to
capture the video signal from the medical device
and relay it to a computer for further processing
and operations.[7]
[edit]Open source software for
medical image analysis
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Several open sourcesoftware packages are
available for performing analysis of medical
images:
ImageJ
3D Slicer
ITK
OsiriX
GemIdent
MicroDicom
FreeSurfer
[edit]Use in pharmaceutical clinical
trials
Medical imaging has become a major tool in
clinical trials since it enables rapid diagnosis with
visualization and quantitative assessment.
A typicalclinical trial goes through multiple phases
and can take up to eight years.Clinical
endpointsor outcomes are used to determine
whether the therapy is safe and effective. Once apatient reaches the endpoint, he/she is generally
excluded from further experimental interaction.
Trials that rely solely onclinical endpoints are very
costly as they have long durations and tend to
need large number of patients.
In contrast to clinical endpoints,surrogate
endpointshave been shown to cut down the time
required to confirm whether a drug has clinical
benefits. Imaging biomarkers (a characteristic that
is objectively measured by an imaging technique,
which is used as an indicator of pharmacological
response to a therapy) and surrogate endpoints
have shown to facilitate the use of small group
sizes, obtaining quick results with good statistical
power.[8]
Imaging is able to reveal subtle change that is
indicative of the progression of therapy that may be
missed out by more subjective, traditional
approaches. Statistical bias is reduced as the
findings are evaluated without any direct patient
contact.
For example, measurement oftumourshrinkage is
a commonly used surrogate endpoint in solid
tumour response evaluation. This allows for faster
and more objective assessment of the effects of
anticancer drugs. In evaluating the extent
ofAlzheimers disease, it is still prevalent to use
behavioural andcognitive tests.MRIscans on the
entire brain can accurately pinpoint hippocampal
atrophy rate while PET scans is able to measure
the brains metabolic activity by measuring regional
glucose metabolism.[8]
An imaging-based trial will usually be made up of
three components:
1. A
realistic
imaging
protocol. The
protocol is an
outline that
standardizes
(as far as
practically
possible) the
way in which
the images
are acquired
http://en.wikipedia.org/wiki/Open_sourcehttp://en.wikipedia.org/wiki/Open_sourcehttp://en.wikipedia.org/wiki/ImageJhttp://en.wikipedia.org/wiki/3DSlicerhttp://en.wikipedia.org/wiki/Insight_Segmentation_and_Registration_Toolkithttp://en.wikipedia.org/wiki/OsiriXhttp://en.wikipedia.org/wiki/GemIdenthttp://en.wikipedia.org/wiki/GemIdenthttp://en.wikipedia.org/wiki/MicroDicomhttp://en.wikipedia.org/wiki/FreeSurferhttp://en.wikipedia.org/w/index.php?title=Medical_imaging&action=edit§ion=17http://en.wikipedia.org/wiki/Clinical_trialhttp://en.wikipedia.org/wiki/Clinical_trialhttp://en.wikipedia.org/wiki/Clinical_endpointhttp://en.wikipedia.org/wiki/Clinical_endpointhttp://en.wikipedia.org/wiki/Clinical_endpointhttp://en.wikipedia.org/wiki/Clinical_endpointhttp://en.wikipedia.org/wiki/Clinical_endpointhttp://en.wikipedia.org/wiki/Clinical_endpointhttp://en.wikipedia.org/wiki/Surrogate_endpointhttp://en.wikipedia.org/wiki/Surrogate_endpointhttp://en.wikipedia.org/wiki/Surrogate_endpointhttp://en.wikipedia.org/wiki/Surrogate_endpointhttp://en.wikipedia.org/wiki/Biomarkershttp://en.wikipedia.org/wiki/Medical_imaging#cite_note-hajnal-7http://en.wikipedia.org/wiki/Medical_imaging#cite_note-hajnal-7http://en.wikipedia.org/wiki/Tumourhttp://en.wikipedia.org/wiki/Tumourhttp://en.wikipedia.org/wiki/Alzheimer%E2%80%99s_diseasehttp://en.wikipedia.org/wiki/Alzheimer%E2%80%99s_diseasehttp://en.wikipedia.org/wiki/Cognitive_testshttp://en.wikipedia.org/wiki/Cognitive_testshttp://en.wikipedia.org/wiki/Cognitive_testshttp://en.wikipedia.org/wiki/MRIhttp://en.wikipedia.org/wiki/MRIhttp://en.wikipedia.org/wiki/Medical_imaging#cite_note-hajnal-7http://en.wikipedia.org/wiki/Medical_imaging#cite_note-hajnal-7http://en.wikipedia.org/wiki/Open_sourcehttp://en.wikipedia.org/wiki/ImageJhttp://en.wikipedia.org/wiki/3DSlicerhttp://en.wikipedia.org/wiki/Insight_Segmentation_and_Registration_Toolkithttp://en.wikipedia.org/wiki/OsiriXhttp://en.wikipedia.org/wiki/GemIdenthttp://en.wikipedia.org/wiki/MicroDicomhttp://en.wikipedia.org/wiki/FreeSurferhttp://en.wikipedia.org/w/index.php?title=Medical_imaging&action=edit§ion=17http://en.wikipedia.org/wiki/Clinical_trialhttp://en.wikipedia.org/wiki/Clinical_endpointhttp://en.wikipedia.org/wiki/Clinical_endpointhttp://en.wikipedia.org/wiki/Clinical_endpointhttp://en.wikipedia.org/wiki/Surrogate_endpointhttp://en.wikipedia.org/wiki/Surrogate_endpointhttp://en.wikipedia.org/wiki/Biomarkershttp://en.wikipedia.org/wiki/Medical_imaging#cite_note-hajnal-7http://en.wikipedia.org/wiki/Tumourhttp://en.wikipedia.org/wiki/Alzheimer%E2%80%99s_diseasehttp://en.wikipedia.org/wiki/Cognitive_testshttp://en.wikipedia.org/wiki/MRIhttp://en.wikipedia.org/wiki/Medical_imaging#cite_note-hajnal-7 -
8/8/2019 upesh chauhan
13/50
using the
various
modalities
(PET,SPEC
T,CT,MRI).
It covers the
specifics in
which images
are to be
stored,
processed
and
evaluated.2. An
imaging
centre that is
responsible
for collecting
the images,
perform
quality
control and
provide tools
for data
storage,
distribution
and analysis.
It is important
for images
acquired atdifferent time
points are
displayed in
a
standardised
format to
maintain the
reliability of
the
evaluation.
Certain
specialised
imaging
contract
research
organizations
provide to
end medicalimaging
services,
from protocol
design and
site
management
through to
data quality
assurance
and image
analysis.
3. Clinical
sites that
recruit
patients to
generate the
images tosend back to
the imaging
centre.
[edit]See also
http://en.wikipedia.org/wiki/PEThttp://en.wikipedia.org/wiki/PEThttp://en.wikipedia.org/wiki/SPECThttp://en.wikipedia.org/wiki/SPECThttp://en.wikipedia.org/wiki/SPECThttp://en.wikipedia.org/wiki/SPECThttp://en.wikipedia.org/wiki/Computed_tomographyhttp://en.wikipedia.org/wiki/Computed_tomographyhttp://en.wikipedia.org/wiki/Magnetic_resonance_imaginghttp://en.wikipedia.org/wiki/Magnetic_resonance_imaginghttp://en.wikipedia.org/w/index.php?title=Medical_imaging&action=edit§ion=18http://en.wikipedia.org/wiki/PEThttp://en.wikipedia.org/wiki/SPECThttp://en.wikipedia.org/wiki/SPECThttp://en.wikipedia.org/wiki/Computed_tomographyhttp://en.wikipedia.org/wiki/Magnetic_resonance_imaginghttp://en.wikipedia.org/w/index.php?title=Medical_imaging&action=edit§ion=18 -
8/8/2019 upesh chauhan
14/50
Preclinical imaging
Cardiac PET
Biomedical informatics
Digital Imaging and Communications in
Medicine
Digital Mammography and PACS
EMMI European Master in Molecular
Imaging
eMix
Fotofinder
Full-body scan
VoluMedic
[edit]References
1. ^ Societ
y of Nuclear
Medicine
2. ^ thefree
dictionary.co
m -
scintigraphyC
iting:
Dorland's
Medical
Dictionary for
Health
Consumers,
2007 by
Saunders;
Saunders
Comprehensi
ve Veterinary
Dictionary, 3
ed. 2007;
McGraw-Hill
Concise
Dictionary of
Modern
Medicine,
2002 by The
McGraw-Hill
Companies
3. ^ abc Dh
awan P, A.
(2003).
Medical
ImagingAnalysis.
Hoboken, NJ:
Wiley-
Interscience
Publication
4. ^ http://
www.breastth
ermography.c
om/breast_the
rmography_m
f.htm
5. ^ Freihe
rr G. Waste
not, want not:
Getting the
most from
imagingprocedures.D
iagnostic
Imaging. Marc
h 19, 2010.
http://en.wikipedia.org/wiki/Preclinical_imaginghttp://en.wikipedia.org/wiki/Cardiac_PEThttp://en.wikipedia.org/wiki/Biomedical_informaticshttp://en.wikipedia.org/wiki/Digital_Imaging_and_Communications_in_Medicinehttp://en.wikipedia.org/wiki/Digital_Imaging_and_Communications_in_Medicinehttp://en.wikipedia.org/wiki/Digital_Mammography_and_PACShttp://en.wikipedia.org/w/index.php?title=EMMI&action=edit&redlink=1http://en.wikipedia.org/wiki/EMixhttp://en.wikipedia.org/wiki/Fotofinderhttp://en.wikipedia.org/wiki/Full-body_scanhttp://en.wikipedia.org/wiki/VoluMedichttp://en.wikipedia.org/w/index.php?title=Medical_imaging&action=edit§ion=19http://en.wikipedia.org/wiki/Medical_imaging#cite_ref-0http://www.snm.org/http://www.snm.org/http://www.snm.org/http://en.wikipedia.org/wiki/Medical_imaging#cite_ref-1http://medical-dictionary.thefreedictionary.com/scintigraphyhttp://medical-dictionary.thefreedictionary.com/scintigraphyhttp://medical-dictionary.thefreedictionary.com/scintigraphyhttp://medical-dictionary.thefreedictionary.com/scintigraphyhttp://medical-dictionary.thefreedictionary.com/scintigraphyhttp://en.wikipedia.org/wiki/Medical_imaging#cite_ref-Dhawan_P_2003_2-0http://en.wikipedia.org/wiki/Medical_imaging#cite_ref-Dhawan_P_2003_2-1http://en.wikipedia.org/wiki/Medical_imaging#cite_ref-Dhawan_P_2003_2-1http://en.wikipedia.org/wiki/Medical_imaging#cite_ref-Dhawan_P_2003_2-1http://en.wikipedia.org/wiki/Medical_imaging#cite_ref-Dhawan_P_2003_2-2http://en.wikipedia.org/wiki/Medical_imaging#cite_ref-3http://www.breastthermography.com/breast_thermography_mf.htmhttp://www.breastthermography.com/breast_thermography_mf.htmhttp://www.breastthermography.com/breast_thermography_mf.htmhttp://www.breastthermography.com/breast_thermography_mf.htmhttp://www.breastthermography.com/breast_thermography_mf.htmhttp://www.breastthermography.com/breast_thermography_mf.htmhttp://en.wikipedia.org/wiki/Medical_imaging#cite_ref-4http://www.diagnosticimaging.com/news/display/article/113619/1541872http://www.diagnosticimaging.com/news/display/article/113619/1541872http://www.diagnosticimaging.com/news/display/article/113619/1541872http://www.diagnosticimaging.com/news/display/article/113619/1541872http://www.diagnosticimaging.com/news/display/article/113619/1541872http://www.diagnosticimaging.com/news/display/article/113619/1541872http://www.diagnosticimaging.com/news/display/article/113619/1541872http://en.wikipedia.org/wiki/Preclinical_imaginghttp://en.wikipedia.org/wiki/Cardiac_PEThttp://en.wikipedia.org/wiki/Biomedical_informaticshttp://en.wikipedia.org/wiki/Digital_Imaging_and_Communications_in_Medicinehttp://en.wikipedia.org/wiki/Digital_Imaging_and_Communications_in_Medicinehttp://en.wikipedia.org/wiki/Digital_Mammography_and_PACShttp://en.wikipedia.org/w/index.php?title=EMMI&action=edit&redlink=1http://en.wikipedia.org/wiki/EMixhttp://en.wikipedia.org/wiki/Fotofinderhttp://en.wikipedia.org/wiki/Full-body_scanhttp://en.wikipedia.org/wiki/VoluMedichttp://en.wikipedia.org/w/index.php?title=Medical_imaging&action=edit§ion=19http://en.wikipedia.org/wiki/Medical_imaging#cite_ref-0http://www.snm.org/http://www.snm.org/http://www.snm.org/http://en.wikipedia.org/wiki/Medical_imaging#cite_ref-1http://medical-dictionary.thefreedictionary.com/scintigraphyhttp://medical-dictionary.thefreedictionary.com/scintigraphyhttp://medical-dictionary.thefreedictionary.com/scintigraphyhttp://en.wikipedia.org/wiki/Medical_imaging#cite_ref-Dhawan_P_2003_2-0http://en.wikipedia.org/wiki/Medical_imaging#cite_ref-Dhawan_P_2003_2-1http://en.wikipedia.org/wiki/Medical_imaging#cite_ref-Dhawan_P_2003_2-2http://en.wikipedia.org/wiki/Medical_imaging#cite_ref-3http://www.breastthermography.com/breast_thermography_mf.htmhttp://www.breastthermography.com/breast_thermography_mf.htmhttp://www.breastthermography.com/breast_thermography_mf.htmhttp://en.wikipedia.org/wiki/Medical_imaging#cite_ref-4http://www.diagnosticimaging.com/news/display/article/113619/1541872http://www.diagnosticimaging.com/news/display/article/113619/1541872http://www.diagnosticimaging.com/news/display/article/113619/1541872 -
8/8/2019 upesh chauhan
15/50
6. ^ Udupa
, J.K. and
Herman, G.
T., 3D
Imaging in
Medicine, 2nd
Edition, CRC
Press, 2000
7. ^ Treatin
g Medical
Ailments in
Real Time
8. ^a
b
Hajnal, J. V.,
Hawkes, D.
J., & Hill, D. L.
(2001).
Medical Imag
e
Registration.
CRC Press.
[edit]Further reading
Burger, Wilhelm;
Burge, Mark
James, eds
(2008). Digital
Image
Processing: An
Algorithmic
Introduction using
Java. Texts in
Computer
Science
series. New
York: Springer
Science+Business
Media.doi:10.100
7/978-1-84628-
968-2.ISBN978-
1-84628-379-6.
Baert, Albert L.,
ed
(2008). Encyclope
dia of Diagnostic
Imaging. Berlin:S
pringer-Verlag.do
i:10.1007/978-3-540-35280-8.ISB
N978-3-540-
35278-5.
Tony F.
Chan and Jackie
Shen
(2005). Image
Processing and
Analysis -
Variational, PDE,
Wavelet, and
Stochastic
Methods. SIAM
Terry
Yoo(Editor)
(2004), Insight
into Images.Robb, RA
(1999). Biomedic
al Imaging,
Visualization, and
Analysis. John
http://en.wikipedia.org/wiki/Medical_imaging#cite_ref-ref3_5-0http://en.wikipedia.org/wiki/Medical_imaging#cite_ref-6http://www.epiphan.com/solutions_new/?arid=16http://www.epiphan.com/solutions_new/?arid=16http://www.epiphan.com/solutions_new/?arid=16http://www.epiphan.com/solutions_new/?arid=16http://en.wikipedia.org/wiki/Medical_imaging#cite_ref-hajnal_7-0http://en.wikipedia.org/wiki/Medical_imaging#cite_ref-hajnal_7-1http://en.wikipedia.org/wiki/Medical_imaging#cite_ref-hajnal_7-1http://en.wikipedia.org/wiki/Medical_imaging#cite_ref-hajnal_7-1http://en.wikipedia.org/wiki/Image_Registrationhttp://en.wikipedia.org/wiki/Image_Registrationhttp://en.wikipedia.org/wiki/Image_Registrationhttp://en.wikipedia.org/wiki/Image_Registrationhttp://en.wikipedia.org/w/index.php?title=Medical_imaging&action=edit§ion=20http://en.wikipedia.org/wiki/New_York_Cityhttp://en.wikipedia.org/wiki/New_York_Cityhttp://en.wikipedia.org/wiki/Springer_Science%2BBusiness_Mediahttp://en.wikipedia.org/wiki/Springer_Science%2BBusiness_Mediahttp://en.wikipedia.org/wiki/Springer_Science%2BBusiness_Mediahttp://en.wikipedia.org/wiki/Digital_object_identifierhttp://en.wikipedia.org/wiki/Digital_object_identifierhttp://dx.doi.org/10.1007%2F978-1-84628-968-2http://dx.doi.org/10.1007%2F978-1-84628-968-2http://dx.doi.org/10.1007%2F978-1-84628-968-2http://dx.doi.org/10.1007%2F978-1-84628-968-2http://dx.doi.org/10.1007%2F978-1-84628-968-2http://en.wikipedia.org/wiki/International_Standard_Book_Numberhttp://en.wikipedia.org/wiki/International_Standard_Book_Numberhttp://en.wikipedia.org/wiki/Special:BookSources/978-1-84628-379-6http://en.wikipedia.org/wiki/Special:BookSources/978-1-84628-379-6http://en.wikipedia.org/wiki/Special:BookSources/978-1-84628-379-6http://en.wikipedia.org/wiki/Special:BookSources/978-1-84628-379-6http://en.wikipedia.org/wiki/Berlinhttp://en.wikipedia.org/wiki/Berlinhttp://en.wikipedia.org/wiki/Springer_Science%2BBusiness_Mediahttp://en.wikipedia.org/wiki/Springer_Science%2BBusiness_Mediahttp://en.wikipedia.org/wiki/Springer_Science%2BBusiness_Mediahttp://en.wikipedia.org/wiki/Digital_object_identifierhttp://en.wikipedia.org/wiki/Digital_object_identifierhttp://en.wikipedia.org/wiki/Digital_object_identifierhttp://dx.doi.org/10.1007%2F978-3-540-35280-8http://dx.doi.org/10.1007%2F978-3-540-35280-8http://en.wikipedia.org/wiki/International_Standard_Book_Numberhttp://en.wikipedia.org/wiki/International_Standard_Book_Numberhttp://en.wikipedia.org/wiki/International_Standard_Book_Numberhttp://en.wikipedia.org/wiki/Special:BookSources/978-3-540-35278-5http://en.wikipedia.org/wiki/Special:BookSources/978-3-540-35278-5http://en.wikipedia.org/wiki/Special:BookSources/978-3-540-35278-5http://en.wikipedia.org/wiki/Tony_F._Chanhttp://en.wikipedia.org/wiki/Tony_F._Chanhttp://en.wikipedia.org/wiki/Tony_F._Chanhttp://jackieneoshen.googlepages.com/ImagingNewEra.htmlhttp://jackieneoshen.googlepages.com/ImagingNewEra.htmlhttp://jackieneoshen.googlepages.com/ImagingNewEra.htmlhttp://jackieneoshen.googlepages.com/ImagingNewEra.htmlhttp://jackieneoshen.googlepages.com/ImagingNewEra.htmlhttp://jackieneoshen.googlepages.com/ImagingNewEra.htmlhttp://jackieneoshen.googlepages.com/ImagingNewEra.htmlhttp://jackieneoshen.googlepages.com/ImagingNewEra.htmlhttp://en.wikipedia.org/wiki/Medical_imaging#cite_ref-ref3_5-0http://en.wikipedia.org/wiki/Medical_imaging#cite_ref-6http://www.epiphan.com/solutions_new/?arid=16http://www.epiphan.com/solutions_new/?arid=16http://www.epiphan.com/solutions_new/?arid=16http://en.wikipedia.org/wiki/Medical_imaging#cite_ref-hajnal_7-0http://en.wikipedia.org/wiki/Medical_imaging#cite_ref-hajnal_7-1http://en.wikipedia.org/wiki/Image_Registrationhttp://en.wikipedia.org/wiki/Image_Registrationhttp://en.wikipedia.org/wiki/Image_Registrationhttp://en.wikipedia.org/w/index.php?title=Medical_imaging&action=edit§ion=20http://en.wikipedia.org/wiki/New_York_Cityhttp://en.wikipedia.org/wiki/New_York_Cityhttp://en.wikipedia.org/wiki/Springer_Science%2BBusiness_Mediahttp://en.wikipedia.org/wiki/Springer_Science%2BBusiness_Mediahttp://en.wikipedia.org/wiki/Springer_Science%2BBusiness_Mediahttp://en.wikipedia.org/wiki/Digital_object_identifierhttp://dx.doi.org/10.1007%2F978-1-84628-968-2http://dx.doi.org/10.1007%2F978-1-84628-968-2http://dx.doi.org/10.1007%2F978-1-84628-968-2http://en.wikipedia.org/wiki/International_Standard_Book_Numberhttp://en.wikipedia.org/wiki/Special:BookSources/978-1-84628-379-6http://en.wikipedia.org/wiki/Special:BookSources/978-1-84628-379-6http://en.wikipedia.org/wiki/Berlinhttp://en.wikipedia.org/wiki/Springer_Science%2BBusiness_Mediahttp://en.wikipedia.org/wiki/Springer_Science%2BBusiness_Mediahttp://en.wikipedia.org/wiki/Digital_object_identifierhttp://en.wikipedia.org/wiki/Digital_object_identifierhttp://dx.doi.org/10.1007%2F978-3-540-35280-8http://dx.doi.org/10.1007%2F978-3-540-35280-8http://en.wikipedia.org/wiki/International_Standard_Book_Numberhttp://en.wikipedia.org/wiki/International_Standard_Book_Numberhttp://en.wikipedia.org/wiki/Special:BookSources/978-3-540-35278-5http://en.wikipedia.org/wiki/Special:BookSources/978-3-540-35278-5http://en.wikipedia.org/wiki/Tony_F._Chanhttp://en.wikipedia.org/wiki/Tony_F._Chanhttp://jackieneoshen.googlepages.com/ImagingNewEra.htmlhttp://jackieneoshen.googlepages.com/ImagingNewEra.htmlhttp://jackieneoshen.googlepages.com/ImagingNewEra.html -
8/8/2019 upesh chauhan
16/50
Wiley & Sons,
Inc. ISBN047128
3533.
Journal of Digital
Imaging(New
York: Springer
Science+Business
Media).ISSN089
7-1889.
Using JPIP for
Standard-
Compliant
Sharing ofMedical Image
Data a white
paper by Aware
Inc.
[edit]External links
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http://www.awar
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at is JPIP?
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8/8/2019 upesh chauhan
17/50
Svenska
Ting Vit
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Medical imagingFrom Wikipedia, the free encyclopedia
This article is about imaging techniques and
modalities for the human body. For imaging ofanimals in research, see Preclinical imaging.
This article needs
additional citations for verif
ication.Please help improve this article byaddingreliable references. Unsourced
material maybechallengedandremoved.(June
2009)
Medical imaging is the technique and process
used to create imagesof the human body (or parts
and function thereof) for clinical purposes (medical
procedures seeking to reveal,diagnose or
examinedisease) or medical science (including the
study of normalanatomy andphysiology). Although
imaging of removed organs andtissues can be
performed for medical reasons, such procedures
are not usually referred to as medical imaging, but
rather are a part ofpathology.
As a discipline and in its widest sense, it is part
ofbiological imaging and incorporatesradiology (in
the wider sense), nuclear medicine,
investigative radiological sciences, endoscopy,
(medical) thermography, medical photography
andmicroscopy (e.g. for human pathological
investigations).
Measurement and recording techniques which are
not primarily designed to produce images, such
as electroencephalography (EEG),magnetoencephalography (MEG), Electrocardiography(EKG) and
others, but which produce data susceptible to be
represented as maps(i.e. containing positional
information), can be seen as forms of medical
imaging.
Contents
[hide]
1 Overview
2 Imaging technology
3 Radiography
o 3.1 Magnetic resonance imaging (MRI)
o 3.2 Nuclear medicine
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