Update on Diversity Cancer Training€¦ · 2. Outline. 1. Overview of CRCHD Programs. 2. The...
Transcript of Update on Diversity Cancer Training€¦ · 2. Outline. 1. Overview of CRCHD Programs. 2. The...
Update on Diversity Cancer Training
Peter Ogunbiyi, DVM, PhDChief, Diversity Training Branch
NCI Center to Reduce Cancer Health Disparities
December 2, 2019
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Outline
1. Overview of CRCHD Programs
2. The Continuing Umbrella of Research Experiences (CURE) Program
3. A Look at FY 2012-2018
4. Moving Forward
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CRCHD Programs
Diversity Training
Partnerships• Partnerships to Advance
Cancer Health Equity (PACHE)
Networks• Geographic
Management of Cancer Health Disparities Program (GMaP)
• National Outreach Network (NON)
Cancer Health Disparities Research
• Basic research• Translational research
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Outline
1. Overview of CRCHD Programs
2. The Continuing Umbrella of Research Experiences (CURE) Program
3. A Look at FY 2012-2018
4. Moving Forward
5
T R A I N E E S
Increase the size of the talent
pool
Emphasize scientific areas of
greatest need
Expand and extend the
period of training
Post-baccalaureate
Grades 6-12
Undergraduate
Predoctoral Investigators
PostdoctoralPost Masters
Continuing Umbrella of Research Experiences
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4%4%
42%
1%
35%
3% 6%
2% 3% 0%Demographics
American Indian or Alaska NativeAsianBlack or African AmericanDisabilityHispanic or LatinoNative Hawaiian or Pacific IslanderUnknownWhiteLow SESMore than One Race
2%
17%
29%25%
2%11%
13%
1%Career Levels
Middle SchoolHigh SchoolUndergraduateGraduatePost-Bac/Post-MastersPostdocInvestigatorsUnknown
CURE Trainees (2001-2018, n = 4,753) Are Diverse
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CURE is More Than a Pipeline
Mentored Research
Experience
Professional Development
Workshop
Mock Review
Virtual Platforms
GMaP:In-Region
Connections
Technical Assistance Workshop
Navigation of Trainees
Ecosystem of Support Set Clear Goals and Monitor Progress
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Outline
1. Overview of CRCHD Programs
2. The Continuing Umbrella of Research Experiences (CURE) Program
3. A Look at FY 2012-20184. Moving Forward
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Diversity and Re-entry Supplements Support Research Experiences Across NCI DOCs (FY 2012 – 2018)
DCB: Division of Cancer BiologyDCCPS: Division of Cancer Control and Population SciencesDCP: Division of Cancer PreventionDCTD: Division of Cancer Treatment and DiagnosisCRCHD: Center to Reduce Cancer Health DisparitiesOD: Office of the Director
n = 661
10%
41%
14%
9%
25%
1%Total Awards by DOC
020406080
100120
2012 2013 2014 2015 2016 2017 2018
Num
ber o
f Aw
ards
Fiscal Year
Supplement Award Distribution
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Diversity and Re-entry Supplements - Demographics and Outcomes(FY 2012-2018)
Reported Supplement Outcomes# K Awards 23# R01 8# R03 2# R21 13# Other Awards 27# Publications 508# Oral Presentations 315
42%
4%
1%
3%47%
1%0%
2%
Diversity
Black / African AmericanAmerican Indian / Alaskan NativeAsianNative Hawaiian / Other Pacific IslanderHispanic / LatinoDisabilitySESRe-entry
Male43%
Female57%
Gender0% 2%
9% 2%
42%28%
17%
Career Level
High SchoolUndergraduatePost-BaccalaureatePost-MastersGraduate StudentPostdoctoralInvestigator
n = 661
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0
20
40
2012 2013 2014 2015 2016 2017 2018Num
ber o
f Aw
ards
F31 Research Type
Basic Behavioral/Population Clinical Translational
F31- Demographics, Research Types and Outcomes (FY 2012-2018)
Cancer Health Disparities Research: 5%
Reported F31 Outcomes# Publications 380# K Awards 5# Other NIH Awards 8
31%2%
3%3%
1%0%
53%
4%
2%1%
Diversity Black / African American
American Indian / AlaskanNativeAsian
Native Hawaiian / OtherPacific IslanderMultiple Races
White
Hispanic / Latino
Disability
SES
Male43%
Female57%
Gender
n = 181
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K Awards – Demographics, Research Types and Outcomes (FY 2012-2018)
Reported K Award Outcomes# Publications 539# R01 15# R03 4# R21 24# Other NIH Awards 10
n = 113
Cancer Health Disparities Research: 22%
010203040
2012 2013 2014 2015 2016 2017 2018
Num
ber o
f Aw
ards
K Award Research Types
Basic Behavioral/Population Clinical TranslationalFiscal Year
43%
2%1%2%1%
47%
4%Diversity
Black / African American
American Indian / AlaskanNativeAsian
Native Hawaiian / OtherPacific IslanderMultiple Races
Hispanic / Latino
Disability
Male40%
Female60%
Gender
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Success Rates of CURE K Awardees in Obtaining Subsequent NIH Grants Compared with Other NIH K Awardees (FY 2001-2015)
Success rate of obtaining R01: CURE similar to other K awardees Success rate of obtaining R03 or R21: Black/African American
CURE K awardees, similar to other groups, perform significantly better than Black/African American Other NIH K Awardees
Comparison Groups: CURE K Awardees All Other NIH K Awardees
All Other NIH K Awardees
White CURE K Awardees
Black/African American Other NIH K Awardees
Black/African American CURE K Awardees
Hispanic/Latino Other NIH K Awardees
Hispanic/Latino
01020304050
Succ
ess
Rat
e (%
) *
05
1015202530
Succ
ess
Rat
e (%
) *
* p < 0.05
Awardee Success Rate Application Success Rate
CURE Ks, B/AA Other NIH Ks, B/AA CURE Ks, B/AA Other NIH Ks, B/AAn: 42 55 153 112 n: 120 128 427 229
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Purpose: YES promotes effective early intervention strategies to: Engage students from diverse backgrounds and
their teachers in cancer research Inspire interest in biomedical sciences and cancer
research Help envision cancer research as a career path Strengthen practical research and career skills
YES Application• Research experiences• Curriculum and Methods
Development• Outreach
YES Career Level• Middle school, high school
and undergraduate students
• Teachers and faculty
R25 Youth Enjoy Science (YES) Research Education Program – Initiated in November, 2016
Distribution of Current 11 R25 YES
15
32%
24%
0%
28%
2%3% 11%
Black / African American
Hispanic / Latino
Native Hawaiian / Other PacificIslanderAmerican Indian / Alaska Native
Asian
White
SES
21 21
35
55
0102030405060
High School Undergraduate
Num
ber o
f Stu
dent
s
Male Female
Middle School Teachers High School Teachers Undergraduate Faculty0 8 9
Student Diversity Student Gender and Career Level
n = 132
R25 YES Demographics, FY2018 (5 Programs, First Year)
3 of the programs will recruit middle school students starting Year 2
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R25 YES Impact Scores: Awards Limited by Budget Constraints
How many can be awarded?
Budget per award per year:Up to $500k DC
($540k TC)
Each award: up to 5 years
Applications Awarded Excellent But Not Awarded Not Awarded Total
FY 2018Score 10-25 25-30 31-65 ND
33Number 5 8 12 8
FY 2019Score 10-20 23-28 36-70 ND
32Number 6 3 19 4
Applications Reviewed Awaiting Review Total
FY 2020Score 14-20 23-30 31-65 ND N/A
40Number 5 3 12 4 16
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Intramural Diversity-Focused Training Program: Intramural CURE (iCURE) – Initiated in December, 2017
Website: https://www.cancer.gov/about-nci/organization/crchd/diversity-training/icure
Purpose: • Support research experiences of underrepresented students and scientists in the
NCI Intramural Research Program in Bethesda, Rockville and Frederick, Maryland • Promote professional and career development • Help the trainees achieve research independence
Post-baccalaureate (Incl. Post-master’s)
One-year research experience awards
Graduate Students Postdoctoral Fellows
Three-year research experience awards
Two-year research experience awards
Applications NOW OPENNov 20, 2019 – Jan 17, 2020
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Outline
1. Overview of CRCHD Programs
2. The Continuing Umbrella of Research Experiences (CURE) Program
3. A Look at FY 2012-2018
4. Moving Forward
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Improve the competitiveness of Postdoctoral Fellows and Investigators
Improve tracking of trainees to better evaluatethe impact of the programs
Moving forward …
Increase R25 YES budget: building a pipeline of diversity-focused training is the foundation of a diverse pool of R01 grantees
Promote training in quantitative sciences – new initiatives
Continue enhancement of training opportunities in cancer health disparities research
Diversity Training
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ContactPeter Ogunbiyi, DVM, PhD
@NCICRCHDhttps://www.cancer.gov/about-nci/organization/crchd
Acknowledgements
DTBSara Hargrave, PhD, MSAlison Lin, PhDNicole McNeil Ford, PhDJohn Ojeifo, MD, PhD, MBAElena Schwartz, PhD, MSMulualem Tilahun, DVM, PhDRita LaPointe, MBASusan Macharia
iCUREAlison Lin, PhDJessica Calzola, PhD, PMPEric Johnson Chavarria, PhDEtaria Omekwe, MS
Training NavigationHana Odeh, PhD
www.cancer.gov www.cancer.gov/espanol