UKMi Medicines Q&As Links to NICE Evidence Search April 2013

Hyperlinks

Anaesthesia ENT Nutrition and blood

Breast-feeding Eye Obs, gynae and urinary tract

Cardiovascular Gastrointestinal Palliative

Children Infections Pregnancy

CNS Liver disease Renal disease

Complementary medicine Malignancies Respiratory

Dental Miscellaneous Skin

Endocrine Musculoskeletal Immunological products/vaccines

*Titles in red - links not yet available

BNF 01 Gastrointestinal system

What are the differences between different brands of mesalazine tablets?

What are the differences between non-oral mesalazine preparations?

How should continuous infusions of branded proton pump inhibitors be given for acute upper gastrointestinal bleeding?

Proton-pump-inhibitors for treatment of reflux in a breastfeeding mother: which is preferred?

Can high dose loperamide be used to reduce stoma output?

Is topical glyceryl trinitrate for anal fissure compatible with breastfeeding?

Histamine H2-receptor antagonists – are they safe in breastfeeding?

Can the use of proton pump inhibitors increase the risk of community acquired pneumonia infection?

Is there an interaction between warfarin and proton pump inhibitors?

Is there an interaction between bisphosphonates and proton pump inhibitors?

Do proton pump inhibitors reduce the clinical efficacy of clopidogrel?

Can proton pump inhibitors be used during pregnancy?

How effective are topical calcium channel blockers for anal fissure?

What is the optimal prokinetic dose of erythromycin in adults?

Do gastric adverse events influence the choice of bisphosphonate for the treatment of osteoporosis?

What is the risk of gastrointestinal bleeding associated with selective serotonin reuptake inhibitors (SSRIs)?

Is there evidence to support the use of enteric coated (EC) aspirin to reduce gastrointestinal side effects in cardiovascular patients?

Clostridium difficile infection – are acid suppressant medicines a risk factor?

What is the evidence for nicotine replacement therapy for ulcerative colitis?

Can acetarsol be used to treat proctitis?

What is St Mark's Electrolyte mix (solution)?

Proton-pump-inhibitors for treatment of reflux in a breastfeeding mother: which is preferred?

BNF 02 Cardiovascular system

Do proton pump inhibitors reduce the clinical efficacy of clopidogrel?

Is there an interaction between warfarin and proton pump inhibitors?

Thromboprophylaxis in patients already on dual antiplatelet therapy: what is good practice?

What doses of thromboprophylaxis are appropriate for adult patients at extremes of body weight?

Is it safe to prescribe NSAIDs with dabigatran etexilate and rivaroxaban?

What are the recommendations for placement/removal of epidural catheters in patients receiving concurrent thromboprophylaxis?

What is the evidence for the use of nebulised heparin in cystic fibrosis?

What is the paediatric dose of oral isosorbide dinitrate/mononitrate?

Can small volume intramuscular injections be given to patients taking oral anticoagulants?

Does warfarin interact with oseltamivir or zanamivir?

Should heparin based flushing solutions be used in preference to saline to maintain the patency of indwelling intravascular catheters and cannulae?

Can a person on low dose aspirin take ginkgo?

What is the available evidence for the use of statins in patients with renal impairment?

Are low molecular weight heparins preferred to unfractionated heparin in people with renal impairment for treatment indications?

Should prophylactic doses of low molecular weight heparins be used in patients with renal impairment?

Is there a lactose-free lipid regulating medicine?

Is there an interaction between erythromycin and statins?

What is the evidence for verapamil for prevention of cluster headache?

Is there evidence to support the use of aspirin for prevention of venous thromboembolism during long haul flights?

Is there evidence to support the use of enteric coated (EC) aspirin to reduce gastrointestinal side effects in cardiovascular patients?

Is there an interaction between grapefruit juice and statins?

Surgical management of the primary care dental patient on antiplatelet medication

Do patients undergoing dental procedures require endocarditis prophylaxis?

Can miconazole oral gel be used by patients taking a statin?

What are the reported incidences of ankle oedema with different calcium channel blockers?

How should ankle oedema caused by calcium channel blockers be treated?

Do statins cause amnesia?

What is the evidence for an increased rate of myocardial infarction associated with calcium supplements?

What is the rationale and evidence for combining angiotensin converting enzyme inhibitors with angiotensin II receptor antagonists in heart failure?

Do statins cause alopecia?

What is the antidepressant of choice in coronary heart disease?

What is the rationale and evidence for combining angiotensin converting enzyme inhibitors with angiotensin II receptor antagonists in vascular diseases and hypertension?

What is the rationale and evidence for combining angiotensin converting enzyme inhibitors with angiotensin II receptor blockers in renal disease?

Should patients on statins take coenzyme Q10 supplementation to reduce the risk of myotoxicity?

How do amlodipine and felodipine compare for the treatment of hypertension or prophylaxis of stable angina?

What are appropriate doses to use when switching hypertensive patients to amlodipine from lercanidipine or lacidipine?

Can angiotensin II receptor antagonists be used if angioedema occurred with an ACE inhibitor?

How effective are topical calcium channel blockers for anal fissure?

Do statins cause amnesia?

What is the evidence for an increased rate of myocardial infarction associated with calcium supplements?

What are appropriate doses to use when switching hypertensive patients to amlodipine from lercanidipine or lacidipine?

Oral antiplatelet agents – are they safe in breastfeeding?

BNF 03 Respiratory

What is the evidence for the use of nebulised heparin in cystic fibrosis?

Which oral antihistamines are available in lactose-free formulations?

Do oxygen cylinders need to be prescribed on an individual patient basis in residential nursing homes?

What medicines should be avoided by patients suffering from “sulfa-allergy”?

How should talc be administered for chemical pleurodesis?

Can nonsteroidal anti-inflammatory drugs be used in adult patients with asthma?

What is the evidence for the use of salbutamol to treat hyperkalaemia?

What practical issues need to be considered for the use and care of spacer devices?

How is an intravenous aminophylline dose converted to an oral aminophylline or theophylline dose?

Which medicines can be used to treat intermittent allergic rhinitis during pregnancy?

Which commonly used nebuliser solutions are compatible?

BNF 04 CNS

What is the risk of gastrointestinal bleeding associated with selective serotonin reuptake inhibitors (SSRIs)?

What is the evidence for verapamil for prevention of cluster headache?

Do statins cause amnesia?

What is the antidepressant of choice in coronary heart disease?

What are the equivalent doses of oral morphine to other oral opioids when used as analgesics in adult palliative care?

What evidence is available for the use of antidepressants for the management of menopausal hot flushes?

Is melatonin effective for preventing cluster headache?

Can tricyclic antidepressants cause tinnitus?

Is it illegal for a patient to chew "khat" (or "qat") in UK hospitals?

How do you convert from co-beneldopa (Madopar) prolonged-release capsules to dispersible tablets?

What is the first choice antidepressant for patients with renal impairment?

What are the equivalent doses of oral benzodiazepines?

Which opioids can be used in renal impairment?

How should conversion from oral morphine to fentanyl patches be carried out?

What is the evidence to support the use of IV paracetamol for the short-term treatment of moderate to severe pain?

What is the risk of interaction between opioid analgesics and monoamine oxidase inhibitors (MAOIs)?

Can methylphenidate be used for adults with attention deficit hyperactivity disorder (ADHD)?

What is the evidence for low dose naltrexone for treatment of multiple sclerosis?

Does progesterone or progestogen supplementation prevent postnatal depression?

Can antiepileptics (anticonvulsants) increase the risk of osteoporosis?

Why is there a limit on the dose and duration of use for carbamazepine suppositories?

If antidepressant-induced hyponatraemia has been diagnosed, how should the depression be treated?

How should dentists prescribe, store, order and dispose of controlled drugs?

Sinemet shortage - suggested alternatives for primary care

Fish oil supplements - is there evidence that they improve concentration and behaviour in children?

Triptans and SSRI antidepressants - is there an interaction?

Medication-overuse headache: what is it and how do you treat it?

Switching between tricyclic, SSRI and related antidepressants

Switching between monoamine oxidase inhibitors and SSRI, tricyclic or related antidepressants

Which antidepressants are available in lactose-free formulations?

Is there an interaction between orlistat and levothyroxine?

Is memantine effective in the treatment of nystagmus?

How do you switch between pregabalin and gabapentin for neuropathic pain, and vice versa?

What is the evidence for nicotine replacement therapy for ulcerative colitis?

Should patients with epilepsy be changed from phenytoin sodium capsules to tablets and vice versa?

How should nausea and vomiting be treated during pregnancy?

What is the most appropriate antidepressant to use in persons with epilepsy?

What is a suitable combined oral contraceptive pill in a patient who is taking hepatic enzyme-inducing drugs such as carbamazepine or phenytoin?

Can opioids be used for pain relief during pregnancy?

Which medicines prevent Acute Mountain sickness?

Risk of developing Serotonin Syndrome following concomitant use of tramadol with selective serotonin reuptake inhibitors

Can breastfeeding mothers take codeine?

Can breastfeeding mothers take paracetamol?

Gabapentin and pregabalin—are they safe whilst breastfeeding?

What is the risk of gastrointestinal bleeding associated with selective serotonin reuptake inhibitors (SSRIs)?

Management of depression in breastfeeding mothers – what are the general principles?

Management of depression in breastfeeding mothers – are reboxetine, venlafaxine, duloxetine, mirtazapine and MAOIs safe?

Management of depression in breastfeeding mothers – are St Johns Wort and other complementary therapies safe?

Management of depression in breastfeeding mothers – are tricyclic antidepressants safe?

Management of depression in breastfeeding mothers – are selective serotonin reuptake inhibitor (SSRIs) safe?

How should depression be treated in a patient with Parkinson's disease?

What is the preferred triptan for the treatment of migraine in breastfeeding mothers?

Lamotrigine – is it safe to take while breastfeeding?

BNF 05 Infections

What is the optimal prokinetic dose of erythromycin in adults?

Can the use of proton pump inhibitors increase the risk of community acquired pneumonia infection?

Does warfarin interact with oseltamivir or zanamivir?

Is there an interaction between erythromycin and statins?

Can miconazole oral gel be used by patients taking a statin?

How should threadworms be treated during pregnancy?

Can zanamivir be given to patients with renal impairment or patients on renal replacement therapies?

Can oseltamivir be used in adult patients on renal replacement therapies?

Can oseltamivir be used in adult patients with renal impairment?

Which antibiotics should be used to treat colonized central venous catheters and how should they be administered?

When should gentamicin levels be taken after once daily administration?

Is there a 10% cross-sensitivity between penicillins and cephalosporins?

Can a 2 gram dose of flucloxaxillin be given as a slow intravenous injection?

How do you prepare and administer intravenous co-trimoxazole in fluid restricted patients?

Use of oseltamivir in patients taking methotrexate

Clostridium difficile infection – are acid suppressant medicines a risk factor?

Clostridium difficile infection – which antimicrobials are implicated?

Clostridium difficile infection – are probiotics useful?

Can oral fluconazole be used during pregnancy?

What is the clinical significance of the interaction between methotrexate and penicillins?

What information is NHS Direct giving patients about oseltamivir (Tamiflu)?

How do you treat syphilis with parenteral benzylpenicillins?

Are penicillins and cephalosporins safe in breastfeeding?

Oseltamivir or zanamivir – can mothers breastfeed after treatment for influenza?

Can oral fluconazole be used with breastfeeding?

Metronidazole – is it safe to use with breastfeeding?

Malaria prophylaxis – what can be given to breastfeeding mothers?

Chloramphenicol – is it safe in breastfeeding?

How should pubic lice be treated in a breastfeeding mother?

How should head lice be treated in a breastfeeding mother?

Do patients with hydrocephalus shunts need antibiotic prophylaxis before undergoing dental procedures?

BNF 06 Endocrine

Do gastric adverse events influence the choice of bisphosphonate for the treatment of osteoporosis?

Is there an interaction between bisphosphonates and proton pump inhibitors?

Can oral bisphosphonates be given to people with renal impairment to treat osteoporosis?

Can patients on levothyroxine take sea kelp?

Can antiepileptics (anticonvulsants) increase the risk of osteoporosis?

What steroid supplementation is required for a patient with primary adrenal insufficiency undergoing a dental procedure?

Mixtard 30 discontinuation – suggested alternatives for primary care

Are adults taking corticosteroids for adrenal insufficiency at risk of osteoporosis?

When is self-monitoring of blood glucose recommended in Type 2 diabetes?

Is there an interaction between orlistat and levothyroxine?

Do gastric adverse events influence the choice of bisphosphonate for the treatment of osteoporosis?

What are the risks of ocular adverse effects with bisphosphonate treatment?

What is the evidence for use of weekly alendronic acid in men?

What is the rationale for using a combination of levothyroxine and liothyronine (such as Armour Thyroid) to treat hypothyroidism?

What is the equivalent dose of oral prednisolone to intravenous (IV) hydrocortisone?

What effect does metformin have on hirsutism and acne in women with polycystic ovary syndrome?

What effect does metformin have on insulin resistance or the development of diabetes in women with polycystic ovary syndrome?

What effect does metformin have on obesity and the cardiovascular problems seen in women with polycystic ovary syndrome?

How effective is metformin compared to the oral contraceptive pill in women with PCOS?

BNF 07 Obstetrics, gynaecology and urinary tract

Is there a lactose-free hormone replacement therapy (HRT)?

What evidence is available for the use of antidepressants for the management of menopausal hot flushes?

What non-hormonal alternatives to antidepressants are available for the management of menopausal hot flushes?

Which drugs can suppress or inhibit lactation?

Is there a lactose-free oral contraceptive?

Does progesterone or progestogen supplementation prevent postnatal depression?

Is there an interaction between St John’s Wort and combined and progestogen only hormonal contraceptives?

Does St John’s Wort interact with emergency hormonal contraception?

Does horny goat weed work for erectile dysfunction?

What oral treatments are effective at treating Peyronie’s disease?

What is the rationale and evidence for the use of regular, rather than on-demand, dosing of phosphodiesterase-5 inhibitors after radical prostatectomy?

What is a suitable combined oral contraceptive pill in a patient who is taking hepatic enzyme-inducing drugs such as carbamazepine or phenytoin?

Emergency contraception and breast-feeding

Can mothers breastfeed after a medical termination of pregnancy?

What effect does metformin have on hirsutism and acne in women with polycystic ovary syndrome?

What effect does metformin have on insulin resistance or the development of diabetes in women with polycystic ovary syndrome?

What effect does metformin have on obesity and the cardiovascular problems seen in women with polycystic ovary syndrome?

How effective is metformin compared to the oral contraceptive pill in women with polycystic ovary syndrome?

BNF 08 Malignancies and immunosuppression

Is there a topical preparation of chlormethine available for the treatment of mycosis fungoides?

How should talc be administered for chemical pleurodesis?

Use of oseltamivir in patients taking methotrexate

Is methotrexate therapy associated with an increased risk of leukaemia?

What is the evidence for subcutaneous mistletoe extract in the treatment of cancer?

How can hot flushes in men being treated for prostate cancer be managed?

Can mothers breastfeed while taking azathioprine?

BNF 09 Nutrition and blood

Should heparin based flushing solutions be used in preference to saline to maintain the patency of indwelling intravascular catheters and cannulae?

What is the evidence for an increased rate of myocardial infarction associated with calcium supplements?

Can magnesium sulphate be given subcutaneously?

Can patients with peanut allergy take calcium and vitamin D supplements?

What are the excipients in calcium supplements?

Can potassium be given by subcutaneous infusion?

Can epoetin be used in Jehovah's Witness patients in accordance with their beliefs?

Magnesium sulfate injection: converting between millimoles, milligrams and percentage w/v

What oral magnesium preparations are available in the UK and which preparation is preferred for the treatment and prevention of hypomagnesaemia?

Is there a suitable vitamin D product for a patient with a peanut or soya allergy?

What guidance is there available on the use of vitamin K for the management of obstetric cholestasis?

Is there a calcium and vitamin D preparation which is suitable for a vegetarian or vegan?

What is the gluten content of oral prescription medicines?

Is there any evidence for the use of vitamin E in ME?

What dose of vitamin D should be prescribed for the treatment of vitamin D deficiency?

What is the dose of folic acid to use with methotrexate therapy for rheumatoid arthritis?

What is the evidence for the use of salbutamol to treat hyperkalaemia?

How is acute hypomagnesaemia treated in adults?

How is acute hypermagnesaemia treated in adults?

How is acute hypocalcaemia treated in adults?

How is acute hypophosphataemia treated in adults?

How is acute hyperphosphataemia treated in adults?

Antioxidants and zinc for age-related macular degeneration

Fish oil supplements in dyslexia - is there evidence of benefit?

What is the sodium content of medicines?

What is the evidence for an increased rate of myocardial infarction associated with calcium supplements?

Can cobalamins be used to treat low vitamin B12 levels in pregnancy?

Which Vitamin D preparations are suitable for a vegetarian or vegan diet?

How do I use Cosmofer (iron dextran) total dose infusion for correction of iron deficiency anaemia?

What medicines are considered safe for use in the acute porphyrias?

How should intravenous (IV) potassium chloride be administered in adults?

BNF 10 Musculoskeletal and joints

Is it safe to prescribe NSAIDs with dabigatran etexilate and rivaroxaban?

Should patients on statins take coenzyme Q10 supplementation to reduce the risk of myotoxicity?

Can strontium ranelate be given to patients with renal impairment or patients on renal replacement therapies?

What is the dose of folic acid to use with methotrexate therapy for rheumatoid arthritis?

Can nonsteroidal anti-inflammatory drugs be used in adult patients with asthma?

Use of oseltamivir in patients taking methotrexate

Can patients drink alcohol whilst taking long-term low-dose methotrexate?

What is the clinical significance of the interaction between methotrexate and penicillins?

Is methotrexate therapy associated with an increased risk of leukaemia?

How do you convert an oral pyridostigmine dose to a parenteral neostigmine dose?

Should patients on statins take coenzyme Q10 supplementation to reduce the risk of myotoxicity?

Can breastfeeding mothers take ibuprofen?

Chondroitin - drug interactions

Chondroitin – what are the adverse effects?

BNF 11 Eye

Switching between travoprost and generic latanoprost eye drops

Antioxidants and zinc for age-related macular degeneration

What are the risks of ocular adverse effects with bisphosphonate treatment?

BNF 12 ENT

Can tricyclic antidepressants cause tinnitus?

Drug-induced hypersalivation - what treatment options are available?

Hypersalivation - what drug treatment options are available?

Hypersalivation - can hyoscine hydrobromide be used to treat it?

Hypersalivation - can glycopyrronium be used to treat it?

Hypersalivation - what are the treatment alternatives to glycopyrronium and hyoscine?

BNF 13 Skin

Do statins cause alopecia?

Can angiotensin II receptor antagonists be used if angioedema occurred with an ACE inhibitor?

Can fish oils protect against photosensitivity disorders?

Is there a topical preparation of chlormethine available for the treatment of mycosis fungoides?

Can acitretin be given to patients with renal impairment or patients on renal replacement therapies?

Can topical steroids be applied at the same time as emollients?

Use of oseltamivir in patients taking methotrexate

Fumaderm: what is the evidence for its efficacy and safety in psoriasis?

Can patients drink alcohol whilst taking long-term low-dose methotrexate?

What is the clinical significance of the interaction between methotrexate and penicillins?

Is methotrexate therapy associated with an increased risk of leukaemia?

BNF 14 Immunological products & vaccines

What online resources are available to support Human Papillomavirus immunisation?

Yellow fever vaccine – is it safe whilst breastfeeding

BNF 15 Anaesthesia

What effect does low temperature have on cylinders containing a mixture of 50% nitrous oxide and 50% oxygen?

What is the clinical significance of potential drug interactions with local anaesthetic preparations used in primary care dentistry?

Allergy to local anaesthetic agents used in dentistry - what are the signs, symptoms, alternative diagnoses and management options?

Which dental local anaesthetics are latex-free?

Prescribing in breast-feeding

Is topical glyceryl trinitrate for anal fissure compatible with breastfeeding?

Histamine H2-receptor antagonists – are they safe in breastfeeding?

Proton-pump-inhibitors for treatment of reflux in a breastfeeding mother: which is preferred?

Which drugs can suppress or inhibit lactation?

Is it safe to have amalgam fillings placed or removed if breastfeeding?

Are penicillins and cephalosporins safe in breastfeeding?

Oseltamivir or zanamivir – can mothers breastfeed after treatment for influenza?

Can breastfeeding mothers take codeine?

Can oral fluconazole be used with breastfeeding?

Gabapentin and pregabalin—are they safe whilst breastfeeding?

Oral antiplatelet agents – are they safe in breastfeeding?

Metronidazole – is it safe to use with breastfeeding?

Emergency contraception and breast-feeding

Malaria prophylaxis – what can be given to breastfeeding mothers?

Yellow fever vaccine – is it safe whilst breastfeeding

Can mothers breastfeed after a medical termination of pregnancy?

Chloramphenicol – is it safe in breastfeeding?

Can breastfeeding mothers take paracetamol?

Can mothers breastfeed while taking azathioprine?

Proton-pump-inhibitors for treatment of reflux in a breastfeeding mother: which is preferred?

Is it safe for breastfeeding women to take herbal medicines?

Management of depression in breastfeeding mothers – what are the general principles?

Management of depression in breastfeeding mothers – are reboxetine, venlafaxine, duloxetine, mirtazapine and MAOIs safe?

Management of depression in breastfeeding mothers – are St Johns Wort and other complementary therapies safe?

Management of depression in breastfeeding mothers – are tricyclic antidepressants safe?

Management of depression in breastfeeding mothers – are selective serotonin reuptake inhibitor (SSRIs) safe?

What is the preferred triptan for the treatment of migraine in breastfeeding mothers?

Lamotrigine – is it safe to take while breastfeeding?

How should pubic lice be treated in a breastfeeding mother?

How should head lice be treated in a breastfeeding mother?

Drug treatment of inadequate lactation

Prescribing in pregnancy

Can proton pump inhibitors be used during pregnancy?

How should threadworms be treated during pregnancy?

What should you think about when prescribing to pregnant women?

Can oral fluconazole be used during pregnancy?

What information should you provide when phoning UKTIS with an enquiry?

Can cobalamins be used to treat low vitamin B12 levels in pregnancy?

Which medicines can be used to treat intermittent allergic rhinitis during pregnancy?

How should nausea and vomiting be treated during pregnancy?

Can opioids be used for pain relief during pregnancy?

Can breastfeeding mothers take ibuprofen?

Is it safe to take herbal medicines during pregnancy?

Prescribing in renal disease

What is the available evidence for the use of statins in patients with renal impairment?

Should prophylactic doses of low molecular weight heparins be used in patients with renal impairment?

What is the rationale and evidence for combining angiotensin converting enzyme inhibitors with angiotensin II receptor blockers in renal disease?

What is the first choice antidepressant for patients with renal impairment?

Can patients with renal impairment take glucosamine?

Can strontium ranelate be given to patients with renal impairment or patients on renal replacement therapies?

What factors need to be considered when dosing patients with renal impairment?

Can zanamivir be given to patients with renal impairment or patients on renal replacement therapies?

Can oseltamivir be used in adult patients on renal replacement therapies?

Can oseltamivir be used in adult patients with renal impairment?

Does the dose of intravenous fluorescein sodium need to be adjusted in renal impairment or renal replacement therapy?

Can oral bisphosphonates be given to people with renal impairment to treat osteoporosis?

Which opioids can be used in renal impairment?

Can acitretin be given to patients with renal impairment or patients on renal replacement therapies?

Are low molecular weight heparins preferred to unfractionated heparin in people with renal impairment for treatment indications?

Prescribing in liver disease

What is the Child Pugh score?

Why is the adverse effect profile of a drug relevant when prescribing for patients with liver disease?

What pharmacokinetic and pharmacodynamic factors need to be considered when prescribing drugs for patients with liver disease?

Prescribing in dental practice

Surgical management of the primary care dental patient on antiplatelet medication

Do patients undergoing dental procedures require endocarditis prophylaxis?

Patient Group Directions in dental practice

What is the clinical significance of potential drug interactions with local anaesthetic preparations used in primary care dentistry?

How should dentists prescribe, store, order and dispose of controlled drugs?

Fluoride toothpaste - what are the dangers of chronic ingestion in adults?

What steroid supplementation is required for a patient with primary adrenal insufficiency undergoing a dental procedure?

Allergy to local anaesthetic agents used in dentistry - what are the signs, symptoms, alternative diagnoses and management options?

Is it safe to have amalgam fillings placed or removed if breastfeeding?

When can dentists supply medicines?

What are the excipients in toothpastes?

Which dental local anaesthetics are latex-free?

Saliva substitutes: choosing and prescribing the right product

Do patients with hydrocephalus shunts need antibiotic prophylaxis before undergoing dental procedures?

Prescribing in palliative care

What are the equivalent doses of oral morphine to other oral opioids when used as analgesics in adult palliative care?

How should conversion from oral morphine to fentanyl patches be carried out?

Prescribing for children

What is the paediatric dose of oral isosorbide dinitrate/mononitrate?

Olive oil treatment for cradle cap - can it worsen the condition?

Complementary medicine

Can a person on low dose aspirin take ginkgo?

Should patients on statins take coenzyme Q10 supplementation to reduce the risk of myotoxicity?

What side effects does valerian have?

Can patients with renal impairment take glucosamine?

How should herbal medicines be managed in patients undergoing surgery?

What is the evidence for the use of secretin for autism?

Can patients on levothyroxine take sea kelp?

Is there an interaction between St John’s Wort and combined and progestogen only hormonal contraceptives?

Does St John’s Wort interact with emergency hormonal contraception?

Fish oil supplements - is there evidence that they improve concentration and behaviour in children?

Fish oil supplements in dyslexia - is there evidence of benefit?

Glucosamine - what are the adverse effects?

Glucosamine - drug interactions

Does horny goat weed have any clinically significant interactions?

Does horny goat weed work for erectile dysfunction

What are the safety concerns surrounding the use of black cohosh?

What is the evidence for subcutaneous mistletoe extract in the treatment of cancer?

Should patients on statins take coenzyme Q10 supplementation to reduce the risk of myotoxicity?

Chondroitin - drug interactions

Is it safe to take herbal medicines during pregnancy?

Chondroitin – what are the adverse effects?

Is it safe for breastfeeding women to take herbal medicines?

Miscellaneous

What should people do if they miss a dose of their medicine?

What questions do care home staff commonly ask about medicines?

What factors need to be considered when prescribing for lactose intolerant adults?

What do the expiry dates on medicines mean?

What e-learning is available to support medicines management?

What is 'dm+d'?

What are biosimilar medicinal products?

What effect does low temperature have on cylinders containing a mixture of 50% nitrous oxide and 50% oxygen?

Where can I find a list of "E" numbers?

Safe and Secure Handling of Medicines: where can I get hold of a copy of the revised Duthie report?

Do medicines with the same or similar brand names contain identical active ingredients in different countries?

Where can I find SPCs if they're not on the eMC?

What health and medicines advice is available for patients using the internet?

How do I convert from conventional units to SI units?

How can I reduce the risks from mixing injections?

Should my patient buy that “miraculous cure” advertised on the internet or in a magazine?

Is it illegal for a patient to chew "khat" (or "qat") in UK hospitals?

What are the differences between US and UK drug names?

What legal and pharmaceutical issues should be considered when administering medicines covertly?

Which medicines could cause problems for patients during a heatwave?

Why must some medicines be taken with or just after food, or a meal?

Why must some medicines be taken when the stomach is empty?

What is the gluten content of oral prescription medicines?

What online information is available for the NHS about new medicines?

What information is available on drugs in diving?

Do oxygen cylinders need to be prescribed on an individual patient basis in residential nursing homes?

Which injections can be given enterally?

Where can I find out which medical devices and medicinal products contain chlorhexidine?

What practical issues need to be considered for the use and care of spacer devices?

Therapeutic options for patients unable to take solid oral dosage forms

Which medicines should be considered for brand-name prescribing in primary care?

What is the sodium content of medicines?

Which medicines need dose adjustment when a patient stops smoking?

When is self-monitoring of blood glucose recommended in Type 2 diabetes?

What is Neuroleptic Malignant Syndrome?

Which drugs can cause neuroleptic malignant syndrome?

How do the different types of enteral feeding tubes available affect drug administration?

How do I complete a Yellow Card?

Crushing tablets or opening capsules in a care home setting

Arachis oil in medicines – what are the risks of developing peanut allergy?

Drug patents: which will expire in 2013 and 2014?

Which commonly used nebuliser solutions are compatible?