UCSF Life Sciences Week 5 Therapeutics: Revenue Streams

Value PropositionsLean Launchpad: Digital Health

UCSF Entrepreneurship CenterOctober 1, 2013

Abhas Gupta, MDMohr Davidow Ventures

@abhasguptamd

Karl%Handelsman%Codon%Capital%%

Weekly%Office%Hours:%4:30<5:30%before%class%

[email protected]%

Revenue%Streams%

Lean%Launchpad:%TherapeuHcs%%

UCSF%Entrepreneurship%Center%October%29,%2013%

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@abhasguptamd

Revenue%Streams%

This%Week%

Last%Week%

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@abhasguptamd

REVENUE&STREAMS&Business%Development%Examples%




@abhasguptamd

Slicing%the%Salami/Peeling%the%Onion%Partner$one$program$to$fund$development$of$retained$applica/ons$

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@abhasguptamd

Grants,%FoundaHons,%DARPA%Non;dilu/ve$money$progresses$the$goal$

Develop%Core%Technology%or%Product%MeeHng%External%OrganizaHonal%Needs%%examples:% %$40M%Gates%FoundaHon%Prior%To%Amyris%Series%A%% % % %$15M%Series%A%Inviragen%Matched%With%$30M%Vaccine%Grants/Contracts%% % % %Tetraphase:%Large%Government%Grants%for%Anthrax%AnHbioHc%% % % %%

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@abhasguptamd

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@abhasguptamd

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Culture/Talent&Must&Deliver&and&Outperform&Partners&Metrics&

CEO%Fritz%French%thinks%the%publicaHon%of%the%Carmel%company’s%research%on%obesity<fighHng%compounds%by%the%major%scienHfic%journal%*Nature%Chemical%Biology%will%grab%afenHon%of%scienHsts%and%other%drug%companies%around%the%world.“It%gets%us%more%exposure%to%large%pharma%companies%collaboraHng%down%the%road%—%on%other%things,”%French%said.%The%*Nature%arHcle%involved%Marcadia’s%collaboraHve%work%with%New%Jersey<based%drug%giant%Merck%&%Co.%Inc.%But%the%Carmel<based%biotech%firm%has%several%other%obesity%and%diabetes<fighHng%drugs%in%its%pipeline.<%2009%

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Roche%revealed%the%$289.6%million%price%tag%it%paid%to%acquire%diabetes%company%Marcadia%Biotech%Inc.%The%pharma%originally%wanted%to%license%Marcadia's%first<in<class%dual%GLP<1/GIP%receptor%agonist,%but%ended%up%buying%the%company%to%gain%access%to%a%research%collaboraHon%with%Indiana%University,%where%all%the%biotech's%syntheHc%pepHdes%were%discovered.%–Dec%2010%




@abhasguptamd

Business%Models%Structure$and$Stage$

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@abhasguptamd

Remember%•  Biotech%startups%are%bought%not%sold%•  Strategic%value%meets%their%future%goals%– NPV%based%on%past%metrics%is%irrelevant%

•  AucHons/Bidding%Wars/Walking%Away%– Build%Data,%Build%RelaHonships,%Act%Ethically%– Any%“tacHcs”%must%match%the%situaHon%

•  The%sHngy%person%pays%the%most%•  It’s%never%over%Hll%the%money%is%wired%

Our%team%has%broad%deal<making%capabiliHes%with%the%flexibility%to%adapt%the%deal%structures%to%the%science.%%

% % %–%outbound%communicaHon%from%pharma%BD%team%




@abhasguptamd

[email protected]&My%Contact:%Put%LLP%in%Subject%Line%for%extra%points%%

UCSF Life Sciences Week 5 Therapeutics: Revenue Streams

Economy & Finance

Transcript of UCSF Life Sciences Week 5 Therapeutics: Revenue Streams