U05-9799 #015016274755
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U05-9799 #015016274755 •24 Year old female dx SLE April 2005 •Complicated by thromboebolic events including DVT and extensive PE, AIHA, pulm. HTN •March 2005 –Treated in Fort Mac for CAP/ TB –CT showed cavitary lung lesion, TB w/u negative –Had open lung Bx for cavitating lung disease – thromboembolic arteripathy c/w SLE and evidence pulm.HTN –Anti-dsDNA, ANCA neg, ANA pos, HIV/Hep C neg –C3/C4 0.031/0.03 (Low) –P:C 96.67, Cr 30 –Followed by Dr. Aaron and given steroids/plaquenil •May 2005 –Readmitted to hospital for CAP and ? nephrotic syndrome –Cr 48, Alb 22, P:Cr 415.63, LDL1.28, U/A -1-5 RBC, 3+ prot, 0 HB (sg 1.031) cytodiag occ. Heme
description
U05-9799 #015016274755. 24 Year old female dx SLE April 2005 Complicated by thromboebolic events including DVT and extensive PE, AIHA, pulm. HTN March 2005 Treated in Fort Mac for CAP/ TB CT showed cavitary lung lesion, TB w/u negative - PowerPoint PPT Presentation
Transcript of U05-9799 #015016274755
U05-9799 #015016274755•24 Year old female dx SLE April 2005•Complicated by thromboebolic events including DVT and extensive PE, AIHA, pulm. HTN•March 2005
–Treated in Fort Mac for CAP/ TB –CT showed cavitary lung lesion, TB w/u negative–Had open lung Bx for cavitating lung disease – thromboembolic arteripathy c/w SLE and evidence pulm.HTN–Anti-dsDNA, ANCA neg, ANA pos, HIV/Hep C neg–C3/C4 0.031/0.03 (Low)–P:C 96.67, Cr 30–Followed by Dr. Aaron and given steroids/plaquenil
•May 2005 –Readmitted to hospital for CAP and ? nephrotic syndrome–Cr 48, Alb 22, P:Cr 415.63, LDL1.28, U/A -1-5 RBC, 3+ prot, 0 HB (sg 1.031) cytodiag occ. Heme gran casts, wbc casts–O/E BP 121/80, JVP N, 3+ pitting edema
IF• IgG- Moderate mesangial staining• IgA- Mild-moderate mesangial staining• IgM- Moderate mesangial staining• C3- Mild mesangial staining• C1q- Moderate mesangial and vascular staining• Kappa- Mild mesangial staining• Lambda- Moderate mesangial staining• Fibrin- Moderate interstitial staining• Albumin- Mild hyalen droplet change in tubular
cytoplasm
IgG
IgA
IgM
C3
Clq
Clq
Kappa
Lambda
Fibrin
Albumin
Lambda
Kappa
Diagnosis:Renal Biopsy:Mesangial proliferative lupus nephritis of mild activity and no chronicity
