Tuesday January 29 th 2013
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Transcript of Tuesday January 29 th 2013
Tuesday January 29th 2013
• QU: What holds all of your genetic information? Where is it located?
• OBJ: New Seats, Introduction to DNA
INTRO TO DNA
DNA Structure
• DNA is located in the nucleus– DNA stands for DEOXYRIBOSE NUCLEIC ACID
• DNA is a type of nucleic acid– Like starch is a type of carbohydrate
• DNA is made of repeating subunits called NUCLEOTIDES
Chromatin• In the nucleus, DNA is found on long, thin
fibers called Chromatin– Chromatin consists of DNA wound around
proteins called histones– Next the DNA is wrapped into a tight
helical formation
Chromosomes
• When a cell is preparing to divide, chromatin condense into chromosomes
• The human somatic cell (body cell) has 46 chromosomes = diploid– 23 from mom + 23 from dad = 46 total– An egg and sperm cell only has 23 = haploid
Chromosomes
• Before a cell divides, it replicates all of its chromosomes
• Each chromosome now consists of 2 identical joined copies called sister chromatids
• Each sister chromatid is joined by a centromere
Chromosome
Sister Chromatids
Genes
• A section of DNA that codes for a specific trait• You have thousands and thousands of genes
• QU: When DNA is coiled up what is it called?
OBJ: Discovering DNA Structure
WedNesday January 30th 2013
Nucleotide
• There are 4 different types of nucleotides that can be used to build DNA– This is because there are 4 different nitrogen
bases that can be used• Adenine (abbreviated A)• Guanine (G)• Thymine (T)• Cytosine (C)
DNA
• PURINE: Have two rings– To be PURE is Always Good.
• Adenine and Guanine
• PYRIMIDINE: Have only one ring– The other two
• Cytosine and Thymine
DNA: Purine versus Pyrimidine
• DNA overall structure is called a DOUBLE HELIXDNA
• *Strands are connected by hydrogen bonds*(between bases)
2 strands of DNA are Complementary
• QU: Write the complement to the following strand.
A T G C C G T A
• OBJ: DNA Replication
“The most poisonous snake in the world is Belcher's Sea Snake or the Faint-banded Sea Snake (Hydrophis belcheri).”
Thursday January 31st 2013
DNA Replication
• If I said a painting was a replica (or replicated) what does that mean?
• Why do you think it is important that we can replicate DNA?
New nucleotides come in and base pair with the “open” original strand.Results in two strands of DNAThe DNA has been copiedEach DNA molecule has one original strand and one new strand
DNA Replication…• Process of copying the DNA molecule
Original DNA strandNitrogen bases paired up according to base pairing rules
DNA Polymerase separates the bases by breaking the hydrogen bonds holding them together
• This type of replication is known as semi-conservative replication– Start with one helix split into two separate strands
but never “throw away any strands”
Replication
Friday FebRuary 1st 2013
• QU: Replication is __________ because the strands are split and each strand is used in a new DNA molecule.
• OBJ: Quiz, Replication, Replication Review