Trans-nasal endoscopy still sniffing the NHS? · HDTV NBI NBI Field of view 140 140 140 140...

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Trans-nasal endoscopy – still sniffing the NHS? Dr Simon Panter Consultant gastroenterologist South Tyneside NHS Foundation Trust

Transcript of Trans-nasal endoscopy still sniffing the NHS? · HDTV NBI NBI Field of view 140 140 140 140...

Page 1: Trans-nasal endoscopy still sniffing the NHS? · HDTV NBI NBI Field of view 140 140 140 140 Observation range (mm) 2-100 3-100 3-100 3-100 Distal tip diameter (mm) 9.2 5.8 8.9 5.4

Trans-nasal endoscopy – still

sniffing the NHS?

Dr Simon Panter

Consultant gastroenterologist

South Tyneside NHS Foundation Trust

Page 2: Trans-nasal endoscopy still sniffing the NHS? · HDTV NBI NBI Field of view 140 140 140 140 Observation range (mm) 2-100 3-100 3-100 3-100 Distal tip diameter (mm) 9.2 5.8 8.9 5.4

Disclosures

Endoscopy fellow funded by Aquilant -2015

Ad boards/honoraria/travel grants – Astra Zeneca, P&G,

Vifor pharma, Shire, Ferring, Warner Chilcott, Covidien

Reference centre for scope trials and loan equipment

– Olympus, Fuji, Given/Medtronic

Page 3: Trans-nasal endoscopy still sniffing the NHS? · HDTV NBI NBI Field of view 140 140 140 140 Observation range (mm) 2-100 3-100 3-100 3-100 Distal tip diameter (mm) 9.2 5.8 8.9 5.4

Trans-nasal endoscopy – still sniffing

the NHS?

?

TNE

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!What it is

How to

do

Role

TNE

Page 5: Trans-nasal endoscopy still sniffing the NHS? · HDTV NBI NBI Field of view 140 140 140 140 Observation range (mm) 2-100 3-100 3-100 3-100 Distal tip diameter (mm) 9.2 5.8 8.9 5.4

TNE – what it is…

Results in less gagging…

Page 6: Trans-nasal endoscopy still sniffing the NHS? · HDTV NBI NBI Field of view 140 140 140 140 Observation range (mm) 2-100 3-100 3-100 3-100 Distal tip diameter (mm) 9.2 5.8 8.9 5.4
Page 7: Trans-nasal endoscopy still sniffing the NHS? · HDTV NBI NBI Field of view 140 140 140 140 Observation range (mm) 2-100 3-100 3-100 3-100 Distal tip diameter (mm) 9.2 5.8 8.9 5.4
Page 8: Trans-nasal endoscopy still sniffing the NHS? · HDTV NBI NBI Field of view 140 140 140 140 Observation range (mm) 2-100 3-100 3-100 3-100 Distal tip diameter (mm) 9.2 5.8 8.9 5.4
Page 9: Trans-nasal endoscopy still sniffing the NHS? · HDTV NBI NBI Field of view 140 140 140 140 Observation range (mm) 2-100 3-100 3-100 3-100 Distal tip diameter (mm) 9.2 5.8 8.9 5.4
Page 10: Trans-nasal endoscopy still sniffing the NHS? · HDTV NBI NBI Field of view 140 140 140 140 Observation range (mm) 2-100 3-100 3-100 3-100 Distal tip diameter (mm) 9.2 5.8 8.9 5.4
Page 11: Trans-nasal endoscopy still sniffing the NHS? · HDTV NBI NBI Field of view 140 140 140 140 Observation range (mm) 2-100 3-100 3-100 3-100 Distal tip diameter (mm) 9.2 5.8 8.9 5.4

Can we advocate TNE?

Is TNE technically as good as traditional

OGD?

Is it as good for patients?

Is it as good for the NHS?

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Is it…..?

Is TNE technically as good as/better than

traditional OGD? Diagnostic ability

Technical success

Image quality

Views (suction)

Light

Manoeuvrability

Accuracy

Therapeutic ability

Bleeders

Stents

PEG

NJ tube

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Current TNE scopes are NOT….

Limited to 2-way angulation

Limited by inferior optics

Limited by poor illumination

Limited by inadequate biopsy samples

(As) Limited by small biopsy channel

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Technical success TNE <5.9mm = cEGD

TNE high patient acceptability and

preference

Page 15: Trans-nasal endoscopy still sniffing the NHS? · HDTV NBI NBI Field of view 140 140 140 140 Observation range (mm) 2-100 3-100 3-100 3-100 Distal tip diameter (mm) 9.2 5.8 8.9 5.4

Fuji Olympus

EG-

600WR

EG-

580NW2

GIF-

H290

GIF-

XP290N

Image Ultra HD

CMOS

FICE

Super

CCD

FICE

HDTV

NBI NBI

Field of view 140 140 140 140

Observation range (mm) 2-100 3-100 3-100 3-100

Distal tip diameter (mm) 9.2 5.8 8.9 5.4

Insertion diameter (mm) 9.3 5.9 8.9 5.8

Forceps channel

diameter (mm)

2.8 2.4 2.8 2.2

Angulation Up 210

Down 90

Left 100

Right 100

Up 210

Down 90

Left 100

Right 100

Up 210

Down 90

Left 100

Right 100

Up 210

Down 90

Left 100

Right 100

Page 16: Trans-nasal endoscopy still sniffing the NHS? · HDTV NBI NBI Field of view 140 140 140 140 Observation range (mm) 2-100 3-100 3-100 3-100 Distal tip diameter (mm) 9.2 5.8 8.9 5.4

Fuji Olympus

EG-

600WR

EG-

580NW2

GIF-

H290

GIF-

XP290N

Image Ultra HD

CMOS

FICE

Super

CCD

FICE

HDTV

NBI NBI

Field of view 140 140 140 140

Observation range (mm) 2-100 3-100 3-100 3-100

Distal tip diameter (mm) 9.2 5.8 8.9 5.4

Insertion diameter (mm) 9.3 5.9 8.9 5.8

Forceps channel

diameter (mm)

2.8 2.4 2.8 2.2

Angulation Up 210

Down 90

Left 100

Right 100

Up 210

Down 90

Left 100

Right 100

Up 210

Down 90

Left 100

Right 100

Up 210

Down 90

Left 100

Right 100

Page 17: Trans-nasal endoscopy still sniffing the NHS? · HDTV NBI NBI Field of view 140 140 140 140 Observation range (mm) 2-100 3-100 3-100 3-100 Distal tip diameter (mm) 9.2 5.8 8.9 5.4

Fuji Olympus

EG-

600WR

EG-

580NW2

GIF-

H290

GIF-

XP290N

Image Ultra HD

CMOS

FICE

Super

CCD

FICE

HDTV

NBI NBI

Field of view 140 140 140 140

Observation range (mm) 2-100 3-100 3-100 3-100

Distal tip diameter (mm) 9.2 5.8 8.9 5.4

Insertion diameter (mm) 9.3 5.9 8.9 5.8

Forceps channel

diameter (mm)

2.8 2.4 2.8 2.2

Angulation Up 210

Down 90

Left 100

Right 100

Up 210

Down 90

Left 100

Right 100

Up 210

Down 90

Left 100

Right 100

Up 210

Down 90

Left 100

Right 100

Page 18: Trans-nasal endoscopy still sniffing the NHS? · HDTV NBI NBI Field of view 140 140 140 140 Observation range (mm) 2-100 3-100 3-100 3-100 Distal tip diameter (mm) 9.2 5.8 8.9 5.4

Fuji Olympus

EG-

600WR

EG-

580NW2

GIF-

H290

GIF-

XP290N

Image Ultra HD

CMOS

FICE

Super

CCD

FICE

HDTV

NBI NBI

Field of view 140 140 140 140

Observation range (mm) 2-100 3-100 3-100 3-100

Distal tip diameter (mm) 9.2 5.8 8.9 5.4

Insertion diameter (mm) 9.3 5.9 8.9 5.8

Forceps channel

diameter (mm)

2.8 2.4 2.8 2.2

Angulation Up 210

Down 90

Left 100

Right 100

Up 210

Down 90

Left 100

Right 100

Up 210

Down 90

Left 100

Right 100

Up 210

Down 90

Left 100

Right 100

2.2mm channel = 320ml/minute flow rate

2.4mm channel = 500ml/minute flow rate

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Image quality

High definition

Image enhancement

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Accuracy

TNE as good (?better) at diagnosing GORD related diseases

Recent data suggesting equivalent in diagnosing BO

Equivalent in diagnosing and grading varices

Possibly lower pick up small superficial gastric cancers in proximal stomach

Pick up may be improved with chromoendoscopy

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Therapeutic ability

Bleeders – limited – channel for accessories/suction

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Reduced cardiovascular stress

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Therapeutic ability

Bleeders – limited

“Scouting scope” in high risk individuals

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Therapeutic ability

Bleeders – limited

“Assessment” in high risk individuals

Reduced cardiovascular stress

APC

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Therapeutic ability

Bleeders – limited

“Assessment” in high risk individuals

Reduced cardiovascular stress

APC

Stents

Narrower scope allows placement of wire

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Therapeutic ability

Bleeders – limited

“Assessment” in high risk individuals

Reduced cardiovascular stress

APC

Stents

Narrower scope allows placement of wire

NJ tubes

Significantly quicker and easier

Page 28: Trans-nasal endoscopy still sniffing the NHS? · HDTV NBI NBI Field of view 140 140 140 140 Observation range (mm) 2-100 3-100 3-100 3-100 Distal tip diameter (mm) 9.2 5.8 8.9 5.4

Is it better for patients?

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Does improved patient tolerability

translate into a better quality endoscopy?

• Procedure time longer for TNE

• TNE 8.8 +/- 3.2 min vs 7.7 +/- 3.4 p = 0.021

• TNE 10 vs 7 min p=0.0042

1. Alexandris et al APT 20142. Despott et al Gut (Abstract) 2010

Page 30: Trans-nasal endoscopy still sniffing the NHS? · HDTV NBI NBI Field of view 140 140 140 140 Observation range (mm) 2-100 3-100 3-100 3-100 Distal tip diameter (mm) 9.2 5.8 8.9 5.4
Page 31: Trans-nasal endoscopy still sniffing the NHS? · HDTV NBI NBI Field of view 140 140 140 140 Observation range (mm) 2-100 3-100 3-100 3-100 Distal tip diameter (mm) 9.2 5.8 8.9 5.4
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2 x

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Is it better for the NHS?

Less staff allocation per room

No need for “head end” nurse

Shorter recovery time

Prep and procedure time longer

Mitigated if nurses do nasal prep

Lidocaine hydrochloride 5% + phenylephrine

hydrochloride 0.5%

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Move out of the endoscopy

department?

Space in endoscopy at a premium

Outpatients

Community setting

Risk with upper GI endoscopy sedation related

Selected, low risk patients having diagnostic endoscopy

www.freedomfromobesity.net

Page 36: Trans-nasal endoscopy still sniffing the NHS? · HDTV NBI NBI Field of view 140 140 140 140 Observation range (mm) 2-100 3-100 3-100 3-100 Distal tip diameter (mm) 9.2 5.8 8.9 5.4

Barriers?

• Training

• Cost

Page 37: Trans-nasal endoscopy still sniffing the NHS? · HDTV NBI NBI Field of view 140 140 140 140 Observation range (mm) 2-100 3-100 3-100 3-100 Distal tip diameter (mm) 9.2 5.8 8.9 5.4
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Complications/considerations

Failure – rare

Epistaxis – self limiting 2%

Pressure and Naseptin for 1/52

Pack and ENT

Anticoagulants (no good data) – INR<2.5 (?)

Platelet count (no good data) >50 (?)

Slightly higher epistaxis rates (up to 14%)

Nasal fractures – usually not a problem

Frequent epistaxis, HHT contra-indication

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Cost

No robust cost-benefit analysis

Cost savings with fewer nurses

Non sedated

Release space in endoscopy department

vs

Significant investment to provide dedicated TNE list

Switching from PO to TNE scope when opportunity arises

Page 40: Trans-nasal endoscopy still sniffing the NHS? · HDTV NBI NBI Field of view 140 140 140 140 Observation range (mm) 2-100 3-100 3-100 3-100 Distal tip diameter (mm) 9.2 5.8 8.9 5.4

Summary

Is TNE technically as good as/better than traditional OGD?

Yes

Is it as good/better for patients?

Yes

Is it as good/better for the NHS?

Possibly ?

Page 41: Trans-nasal endoscopy still sniffing the NHS? · HDTV NBI NBI Field of view 140 140 140 140 Observation range (mm) 2-100 3-100 3-100 3-100 Distal tip diameter (mm) 9.2 5.8 8.9 5.4

Thank you for your attention