To generate human resource for carry out translational research in frontier areas of Biomedical science

Bridging the gap between basic science skills and bedside problems by initiating translation research program

◦ Methodology:

◦ 1. PhD program ◦ 2. Postgraduate Training program ◦ 3. Seminars/workshops

PhD students completed their degree course S.No PhD student name Status (current position)1. Gaurav Pandey *@ PhD awarded in 2016

(Post.doc at University of Iowa, USA) 2 Ravi Shanker Singh PhD awarded in 2016

( Post.doc at University of Saskatchewan, Canada)

3 Aradhan Mohan PhD awarded in 2016 (on 9th Sept 2016)

4 Praveen Kumar* PhD awarded in 2016 Senior research fellow at SGPGI

5 Aru Singh PhD awarded in 2016 Research Associate- Apollo Hospital. Delhi

Students perusing their PhD 6 Dr. Kriti Joshi Second Doctoral committee met on 8th

Sept 20167 Manju Kumari First Doctoral committee met

on 2nd May 2016

In September 2015, Workshop on confocal microscopy has been organized for faculty, students and research staff of the institute

Scientific Skill development event organized in March 2016

Research Symposium and Wet lab workshop in March 2016

Confocal Microscopy Workshop

Scientific skill development workshop for students from under-resource

universities

Scientific skill development workshop for students from under-resource universities

Wet-lab workshop for students

Research Symposium and Poster Presentation

Build- up state- of- the- art facility for nanovesicle research

Build collaborative research programs with Clinical Departments.

Nanotracking systemValidation of nanovesicles from human

body fluids

Validation of nanovesicles from human body fluids : using Electron microscope and nanotracking analysis.

1. To develop and validate newer biomarkersfor Early Non-invasive diagnosis andprognosis.

An early prediction of developing proteinuriain subjects with diabetes

Longitudinal follow-up study in collaboration with Department of Clinical Endocrinology

Change in Urine Microalbumin levels and HbA1C in a 2 year follow-up: Presence of WT1 in urinary exosomes may predict the risk of developing proteinuria in type-1 diabetic subjects.

1. Mohan A, et al . PLoS ONE 2016 Apr 2111(4): e0154055. doi: 10.1371/journal.pone.2. Pandey G. et al. J Cell Biochem 2016. Jun 20. doi: 10.1002/jcb.256323. Tripathi R et al. Nutr Cancer. 2016 May-Jun;68(4):679-88.4. Pal A et al. Toxicol Appl Pharmacol. 2016 Mar 15;295:12-25.5. Kumar P et al. J Endocrinol. 2015 Nov;227(2):83-92.6. Pandey G et al. J. Biol. Chem. 2015; 290(9):5582-91. (IF- 4.6)7. Khan MP et al. Diabetes. 2015 Jan 29. pii: db141611. (IF: 8.09)8. Mohan A et al. Journal of Diabetes & Metabolism. 2015; 6(3):510. (IF- 3.5)9. Bhatelia K et al Biochim Biophys Acta. 2014 Feb;1842(2):144-53 (IF: 5.09)10.Singh AK et al. Diabetes. 2014 Oct;63(10):3530-44. (IF: 8.09).6. Gautam J et al. Br J Nutr. 2014 Feb 10:1-11. (IF: 3.34).7. Tiwari S*, et al . J Am Soc Nephrol 2013 Jul;24(8):1209-14. (IF: 9.6)8. Kalani A, et. al PLoS One. 2013;8(3):e60177. (IF- 4.4)

Original articles published after 2013

Opening balance on 1st April 2016 ( Without Interest)

Amount received during April-Sept 2016

Amount Spent ( Included All Committed on Sept 2016

Balance available*

1,56,73,126.00 0.00 1,27,66,506.00 29,06,620.00

Item Expenditure Equipment purchase 91,00,000.00Research expenses (consumables) 19,52,808.00Research related travel 0.00Training & Workshop 1,67,368.00Any other (specify) ( Contingency +Manpower) 15,46,330.00

Total (This total should match with Col 3 of Table IV)

1,27,66,506.00

•Expenditure and fund position (in Rs. Lakh only)

•Details of Expenditure made during this period: (in Rs lakhs)

•Note- * The Balance amount will be utilized for Manpower salary , •workshop and training after your permission to carry forward recurring head

S.N Deliverable Likely cost (in Rs lakh)

01 Initiate a collaborative researchproject on type-1 diabetic patientsat SGPGI

Rs.30 lakhs needs to be released – needed to meet Research expenses

02 Wet-lab training and workshop Permission to carry forward non-recurring and recurring head balance from last year for October-March 2016 – needed for Small equipments

03 Field-based studies for large scale validation of our newly-developed tool – we have already collected 100 samples from filed so far (based on our selection criterion).

Permission to carry forward the recurring head balance from last year for October-March 2016 –needed for the existing Manpower hired for this purpose, consumables required

04 human cell lines generation Rs.20 lakhs (15 under recurring head and 5 under nonrecurring head) needs to be released for Manpower, equipment and consumables for this purpose

Total for S.N. 01-04 Rs.50 LakhsGrand total with balance carry forward permission

Rs. 79,06,620.00

Half yearly Plan for the next half year (October-March 2016)

Manpower: 1. Senior Demonstrator Posts These positions have

been approved by the Governing Body of our Institute to gear up the teaching and training at COEs. Two demonstrators have been appointed already.

2. Interviews for 3 new faculty positions (1 Associate and 2 Assistant Professor) have been scheduled in the month of November this year.

For Patient care we are carrying our investigations for high risk pregnancy

Efforts towards Sustainability

Name of the equipment (quantity) Name of the equipment (quantity)

Bio-safety cabinets (02)- Rat and mice Metabolic Cage (12)Waters Purification RO+Milli-Que

(01)Table Top Cold Centrifuge (01)

Real time Thermo cycler –ABI7900 (01)

Ice Making Machine (01)

Deep Freezer (04) Microscope (2)Thermo Cycler (01) IVC Cages (02)

Spectrophotometer (01) Automatic Vibrating blade MicrotomeChemiluminescence’s (01) Individually ventilated cages

CO2 Incubators (01) Electrophoresis System (01)

Major Equipments procured from other resources Resources for COE/ Other support