Thromboprophylaxis in Patients with Acute Spinal Injuries: An Evidence-Based Analysis

by A. Ploumis, R.K. Ponnappan, M.G. Maltenfort, R.X. Patel, J.T. Bessey, T.J. Albert, J.S. Harrop, C.G. Fisher, C.M. Bono, and A.R. Vaccaro

J Bone Joint Surg AmVolume 91(11):2568-2576

November 1, 2009

©2009 by The Journal of Bone and Joint Surgery, Inc.

Flow diagram showing selection procedure for studies comparing unfractionated heparin with low-molecular-weight heparin in patients with acute spinal cord injury (SCI).

A. Ploumis et al. J Bone Joint Surg Am 2009;91:2568-2576

©2009 by The Journal of Bone and Joint Surgery, Inc.

Modified forest plot showing odds ratios (expressed as the mean and the 95% confidence interval) in studies comparing unfractionated heparin with low-molecular-weight heparin in

patients with acute spinal cord injury.

A. Ploumis et al. J Bone Joint Surg Am 2009;91:2568-2576

©2009 by The Journal of Bone and Joint Surgery, Inc.

Meta-analysis plot showing the prevalence of deep-vein thrombosis (expressed as the mean and the 95% confidence interval) in studies comparing unfractionated heparin (UFH) with low-

molecular-weight heparin (LMWH) in patients with acute spinal cord injury.

A. Ploumis et al. J Bone Joint Surg Am 2009;91:2568-2576

©2009 by The Journal of Bone and Joint Surgery, Inc.