Though the administration of intravenous antimicrobials in Ireland has traditionally occurred in...
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Though the administration of intravenous antimicrobials in Ireland has traditionally occurred in in-patient settings/acute hospitals, there is a growing trend internationally to deliver intravenous antimicrobials in a non-inpatient setting. Such programmes are often referred to as 1. out-patient parenteral antimicrobial therapy (OPAT) 2. community-based parenteral antimicrobial therapy (CoPAT) and 3. hospital in the home therapy (HITH) programmes. Although Ireland currently has several productive OPAT programmes, there is a lack of conformity across programmes, including formal national structures of clinical governance and standards of care. OPAT has the potential to deliver bed-day and cost savings and reduce risk of healthcare associated infections (HAIs) if such programmes are expanded throughout the country in a regulated and structured manner. Standards for the administration of out- patient parenteral antimicrobial therapy (OPAT) in Ireland have recently been completed. The working group has proposed standards and clinical governance mechanisms for this mode of care delivery following discussions with the Health Service Executive’s (HSE) National Director for Quality and Clinical Care. The document outlines the benefits of OPAT and reviews infections appropriate for OPAT management. Out-patient parenteral therapy must be governed by the same standards of antimicrobial stewardship, intravascular catheter care and clinical governance as traditional in-patient, hospital-based care. A national registry for all patients receiving OPAT will be established. Proposed models of care delivery, standard operating procedures and management algorithm for patient management are described in the standards document. Over arching aim – To ensure that no patient receiving IV antimicrobials, who could be treated out of hospital, remains an in-patient Quality To save bed days by reducing length of stay and avoiding admission To ensure all patients referred receive appropriate anti microbial stewardship care Patients can return to home / work when appropriate; Patient satisfaction surveys To reduce nosocomial complications associated with long-term IV antimicrobial utilisation Access Provide 5/7 day access to specialist opinion Review all patients within 24 hours of referral and discharge within 24 hours post review if suitable for OPAT Provide direct access for ER, AMAUs, secondary/tertiary care services, primary care Cost Bed days saved through reduced length of stay, admission avoidance Reduction in cost of management of HAIs Antimicrobial stewardship Solutions Proposed: To establish agreed criteria and standards – IDSI/HSE/DoH/RCPI/SARI OPAT Standards 2010 Care pathways -develop and agree a standardised national care pathway and standards of care Introduction of care bundles (antimicrobial stewardship) Define models of care Introduction Benefits of OPAT Management Algorithm for OPAT Care Delivery Outpatient Parenteral Antimicrobial Therapy (OPAT)- Infectious Diseases Patient Benefits Remain at home Remain at work, school Preferred by patients when given choice Reduced risk of health-care associated infection Financial Benefits US – costs 6.5 times less than in- patient care Sheffield - Cost 41% of equivalent inpatient costs for an ID Unit Canada – 57% of in-patient costs Singapore – 61% of in-patient costs Organisational Benefits Oxford, UK – 6,200 bed days saved in 286 OPAT episodes one year SJH – 2166 bed days saved over 3 years MMUH – 2019 bed days save in 3 years CUH, Temple St. – 859 bed days saved in 2 years Meets Irish Health Care Policy Transformation Programme 2007-2010 Health Service Executive. Acute Hospital Bed Capacity Review: A Preferred Health System in Ireland to 2020. PA Consulting 2007 00313-2. Year Commenced No. Patie nts Bed Days Saved Bed Days Saved/ Patient St. James’s Hospital 2006 101 2166 21 Mater Misericor diae Universit y Hospital 2008 66 2019 30 CIT Services (Dublin) AMNCH Northside 2008 2008 253 479 1267 2700 Children’ s Universit y Hospital 2006 30 859 29 Irish Experience – OPAT Programmes Patient Referral Pathways There will be two cohorts of patients for whom OPAT will be provided 1. Patients with acute medical conditions requiring short course of IV therapy ie lower complexity, higher volume 2. Patients requiring ID input for more complex conditions - eg endocarditis, osteomytelitis, septic arthritis – ie more complexity but lower volume Referral for OPAT Assessment by OPAT Teamin hospital or healthcare facility Appropriate Infection Requires Parenteral Antimicrobials Medically Stable Appropriate Vascular Access Patient and Carers Informed Consent Suitable Social Circumstances Methods of Communication Established Source of Antimicrobials and support established Funding secured Accepted to OPAT Programme Minimum of One Dose of Antimicrobial Given in Hospital or Healthcare Facility Assess for Adverse Reaction Patient and Carer Education Discharge to OPAT Programme with plan for duration of therapy and monitoring of response. Assessment at OPAT Clinic (at least weekly) Review by OPAT Physician Monitoring of Response to Therapy Laboratory Monitoring as per antimicrobial guidelines above Assess for medication side-effects Vascular access device monitoring Daily visit by OPAT community healthcare professional/CIT to administer antimicrobials (H- OPAT) Condition fails to improve or complication develops Readmission for therapy Outcomes Database Updated OPAT course completed Clinic Follow-up Communication with referring team Outcomes Database Updated Patient/Carer Administers antimicrobials With/without monitoring by community healthcare professional/CIT (S-OPAT) OPAT Standards Writing Group Aims, Objectives, Solutions Out-patient Parenteral Antimicrobial Therapy in Ireland: Practice Standards Infectious Diseases Society of Ireland (IDSI) OPAT Working Group David P Gallaghe, Audrey O’ Reilly, Fidelma Fitzpatrick, Dubhfeasa M Slattery, Patrick W Mallon, Catherine Fleming Mary Horgan[8], Jacinta Grace-Parker Colm J Bergin Potential Benefits for In-patient Services Review of hospital inpatient data for 2009 shows the number of admissions and hospital beddays used for some of the conditions potentially treatable by an OPAT programme. A fully resourced OPAT programme could lead to defined reductions in admission rates or duration of hospital stay f common conditions like pneumonia, pyelonephritis, cellulitis and reduce LOS for conditions like osteomyelitis, septic arthritis and endocarditis. 2009 Hospital Data: Condition No of Admissions Beddays Used Osteomyelitis 340 5310 Endocarditis 153 428 Septic Arthritis 192 3686 Cellulitis 3877 28264 UTI 6161 51046 Pneumonia 8213 100001
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Transcript of Though the administration of intravenous antimicrobials in Ireland has traditionally occurred in...
Though the administration of intravenous antimicrobials in Ireland has traditionally occurred in in-patient settings/acute hospitals, there is a growing trend internationally to deliver intravenous antimicrobials in a non-inpatient setting. Such programmes are often referred to as1. out-patient parenteral antimicrobial therapy (OPAT) 2. community-based parenteral antimicrobial therapy
(CoPAT) and 3. hospital in the home therapy (HITH) programmes. Although Ireland currently has several productive OPAT programmes, there is a lack of conformity across programmes, including formal national structures of clinical governance and standards of care. OPAT has the potential to deliver bed-day and cost savings and reduce risk of healthcare associated infections (HAIs) if such programmes are expanded throughout the country in a regulated and structured manner.
Standards for the administration of out-patient parenteral antimicrobial therapy (OPAT) in Ireland have recently been completed. The working group has proposed standards and clinical governance mechanisms for this mode of care delivery following discussions with the Health Service Executive’s (HSE) National Director for Quality and Clinical Care. The document outlines the benefits of OPAT and reviews infections appropriate for OPAT management. Out-patient parenteral therapy must be governed by the same standards of antimicrobial stewardship, intravascular catheter care and clinical governance as traditional in-patient, hospital-based care.
A national registry for all patients receiving OPAT will be established. Proposed models of care delivery, standard operating procedures and management algorithm for patient management are described in the standards document.
Over arching aim – To ensure that no patient receiving IV antimicrobials, who could be treated out of hospital, remains an in-patient
QualityTo save bed days by reducing length of stay and avoiding admissionTo ensure all patients referred receive appropriate anti microbial stewardship carePatients can return to home / work when appropriate; Patient satisfaction surveysTo reduce nosocomial complications associated with long-term IV antimicrobial utilisationAccessProvide 5/7 day access to specialist opinion Review all patients within 24 hours of referral and discharge within 24 hours post review if suitable for OPAT Provide direct access for ER, AMAUs, secondary/tertiary care services, primary careCost Bed days saved through reduced length of stay, admission avoidanceReduction in cost of management of HAIsAntimicrobial stewardship
Solutions Proposed:To establish agreed criteria and standards – IDSI/HSE/DoH/RCPI/SARI OPAT Standards 2010 Care pathways -develop and agree a standardised national care pathway and standards of careIntroduction of care bundles (antimicrobial stewardship)Define models of careGovernance- Interface with Acute Medicine Programme (AMAUs) - Initial establishment of 4 regional ID hubs providing the following services:
Direct Emergency Department assessmentRapid access clinic for ED and primary care/secondary
referrals Antimicrobial StewardshipAudit and research
Establishment of a national registry with agreed datasets
Introduction Benefits of OPAT Management Algorithm for OPAT Care Delivery
Outpatient Parenteral Antimicrobial Therapy (OPAT)- Infectious Diseases
Patient BenefitsRemain at homeRemain at work, schoolPreferred by patients when given choiceReduced risk of health-care associated infection
Financial Benefits US – costs 6.5 times less than in-patient care
Sheffield - Cost 41% of equivalent inpatient costs for an ID UnitCanada – 57% of in-patient costsSingapore – 61% of in-patient costs
Organisational BenefitsOxford, UK – 6,200 bed days saved in 286 OPAT
episodes one yearSJH – 2166 bed days saved over 3 yearsMMUH – 2019 bed days save in 3 yearsCUH, Temple St. – 859 bed days saved in 2 years
Meets Irish Health Care Policy Transformation Programme 2007-2010Health Service Executive. Acute Hospital Bed Capacity Review: A Preferred Health System in Ireland to 2020. PA Consulting 2007 00313-2.
YearCommenced
No. Patient
s
Bed Days Saved
Bed Days Saved/Patient
St. James’s Hospital
2006 101 2166 21
Mater Misericordiae
University Hospital
2008 66 2019 30
CIT Services (Dublin)AMNCH
Northside20082008
253479
12672700
Children’s University Hospital
2006 30 859 29
Irish Experience – OPAT Programmes
Patient Referral PathwaysThere will be two cohorts of patients for whom OPAT will be provided
1. Patients with acute medical conditions requiring short course of IV therapy ie lower complexity, higher volume
2. Patients requiring ID input for more complex conditions- eg endocarditis, osteomytelitis, septic arthritis – ie morecomplexity but lower volume
Referral for OPAT
Assessment by OPAT Teamin hospital or healthcare facility
Appropriate InfectionRequires Parenteral Antimicrobials
Medically StableAppropriate Vascular Access
Patient and Carers Informed ConsentSuitable Social Circumstances
Methods of Communication EstablishedSource of Antimicrobials and support established
Funding secured
Accepted to OPAT Programme
Minimum of One Dose of Antimicrobial Given in Hospital or Healthcare Facility
Assess for Adverse ReactionPatient and Carer Education
Discharge to OPAT Programme with plan for duration of therapy and monitoring of response.
Assessment at OPAT Clinic (at least weekly)Review by OPAT Physician
Monitoring of Response to TherapyLaboratory Monitoring as per antimicrobial guidelines above
Assess for medication side-effectsVascular access device monitoring
Daily visit by OPAT community healthcare professional/CIT to administer
antimicrobials (H-OPAT)
Condition fails to improve or complication develops
Readmission for therapyOutcomes Database Updated
OPAT course completed Clinic Follow-up
Communication with referring teamOutcomes Database Updated
Patient/Carer Administers antimicrobials With/without monitoring by community
healthcare professional/CIT(S-OPAT)
OPAT Standards Writing Group
Aims, Objectives, Solutions
Out-patient Parenteral Antimicrobial Therapy in Ireland: Practice Standards
Infectious Diseases Society of Ireland (IDSI)OPAT Working Group
David P Gallaghe, Audrey O’ Reilly, Fidelma Fitzpatrick,
Dubhfeasa M Slattery, Patrick W Mallon, Catherine FlemingMary Horgan[8], Jacinta Grace-Parker
Colm J Bergin
Potential Benefits for In-patient Services
Review of hospital inpatient data for 2009 shows the number of admissions and hospital beddays used for some of the conditions potentially treatable by an OPAT programme.
A fully resourced OPAT programme could lead to defined reductions in admission rates or duration of hospital stay for common conditions like pneumonia, pyelonephritis, cellulitis and reduce LOS for conditions like osteomyelitis, septic arthritis and endocarditis.
2009 Hospital Data:Condition No of Admissions Beddays Used
Osteomyelitis 340 5310 Endocarditis 153 428 Septic Arthritis 192 3686Cellulitis 3877 28264 UTI 6161 51046 Pneumonia 8213 100001
