Therapeutically relevant bioassays
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Archive, Mine, Collaborate 2016 Collaborative Drug Discovery, Inc. Town Hall Webinar NIH & Georgetown University Discuss Therapeutically Relevant Bioassays December 7, 2016
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Transcript of Therapeutically relevant bioassays
Archive, Mine, Collaborate© 2016 Collaborative Drug Discovery, Inc.
Town Hall Webinar
NIH & Georgetown University Discuss Therapeutically Relevant Bioassays
December 7, 2016
Archive, Mine, Collaborate© 2016 Collaborative Drug Discovery, Inc.
Our Moderators
Kellan Gregory, CDDDirector of Product Excellence
Frank Cole, CDDHead of Sales, Eastern USA
Archive, Mine, Collaborate© 2016 Collaborative Drug Discovery, Inc.
Our Panelists
Nathan Coussens, Senior Research Scientist, Biology, Division of Pre-Clinical Innovation, National Center for Advancing Translational Sciences, NCATS/NIH
Paul Roepe, Professor of Chemistry, Professor of Biochemistry & Cell. and Mol. Biol., Co-director, Center for Infectious Disease, Georgetown University
Archive, Mine, Collaborate© 2016 Collaborative Drug Discovery, Inc.
https://ncats.nih.gov/expertise/preclinical/agm Website:Email us: [email protected]
Facebook: www.facebook.com/assayguide
“Dissemination of Tribal Knowledge in Drug Discovery Assay Development” -Doug Auld, Novartis
Archive, Mine, Collaborate© 2016 Collaborative Drug Discovery, Inc.
NCATS Hosts Inaugural Assay Guidance Workshop for High-Throughput Screening and Lead Discovery
Archive, Mine, Collaborate© 2016 Collaborative Drug Discovery, Inc.
Paul Roepe
Archive, Mine, Collaborate© 2016 Collaborative Drug Discovery, Inc.
Nathan Coussens
“Development and Applications of the Bioassay Ontology (BAO) to Describe and Categorize High-Throughput Assays”
(by Uma Vempati and Stephan Schurer)?
Archive, Mine, Collaborate© 2016 Collaborative Drug Discovery, Inc.
BioAssay Ontology & BioAssay Express
http://bioassayontology.org/
https://cheminf20.org/2016/09/29/bioassay-express-finding-assays-and-doing-stuff-with-them/
Archive, Mine, Collaborate© 2016 Collaborative Drug Discovery, Inc.
"New Tools for Combinatorial Screening of Drug Libraries"
Archive, Mine, Collaborate© 2016 Collaborative Drug Discovery, Inc.
CDD Public Access
Malaria is represented in via CDD Public Access under Public Data
Projects descriptions
Projects to search and mine
Archive, Mine, Collaborate© 2016 Collaborative Drug Discovery, Inc.
“I found the workshop highly illuminating, useful to those new to the field, but also to those who might be experts focused on specific aspects.” Professor Jonathan Baell, Ph.D., Co-Director, Australian
Translational Medicinal Chemistry Facility Monash Institute of Pharmaceutical Sciences
“I found the recent NIH Assay Guidance workshop an excellent refresher on assay development guidelines for high-throughput screening, and I also learned a few important new facts. This was very worthy for new and seasoned investigators.” Melvin Reichman, Ph.D., Director, LIMR Chemical Genomics Center
Senior Investigator, Lankenau Institute for Medical ResearchChairman of the Board, International Chemical Biology Society
NCATS and Promega Host Assay Guidance Workshop for High-Throughput Screening and Lead Discovery
Archive, Mine, Collaborate© 2016 Collaborative Drug Discovery, Inc.
Next Assay Guidance Workshop will be with the Society for Laboratory Automation and Screening
www.slas2017.org/program/assay-guidance.cfm
Archive, Mine, Collaborate© 2016 Collaborative Drug Discovery, Inc.
Mosquito Transmitted Disease
Archive, Mine, Collaborate© 2016 Collaborative Drug Discovery, Inc.
Nathan Coussens
“
Archive, Mine, Collaborate© 2016 Collaborative Drug Discovery, Inc.
Archive, Mine, Collaborate© 2016 Collaborative Drug Discovery, Inc.
Archive, Mine, Collaborate© 2016 Collaborative Drug Discovery, Inc.
Archive, Mine, Collaborate© 2016 Collaborative Drug Discovery, Inc.
Cytocidal Readout
Archive, Mine, Collaborate© 2016 Collaborative Drug Discovery, Inc.
Cytostatic vs Cytocidal assays
Archive, Mine, Collaborate© 2016 Collaborative Drug Discovery, Inc.
Nathan Coussens, Senior Research Scientist, Biology, Division of Pre-Clinical Innovation, National Center for Advancing Translational Sciences, NCATS/NIH
Paul Roepe, Professor of Chemistry, Professor of Biochemistry & Cell. and Mol. Biol., Co-director, Center for Infectious Disease, Georgetown University
Archive, Mine, Collaborate© 2016 Collaborative Drug Discovery, Inc.
Questions?
Archive, Mine, Collaborate© 2016 Collaborative Drug Discovery, Inc.
Q&A with our Panelists
Nathan Coussens, Senior Research Scientist, Biology, Division of Pre-Clinical Innovation, National Center for Advancing Translational Sciences, NCATS/NIH
Paul Roepe, Professor of Chemistry, Professor of Biochemistry & Cell. and Mol. Biol., Co-director, Center for Infectious Disease, Georgetown University
Archive, Mine, Collaborate© 2016 Collaborative Drug Discovery, Inc.
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