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    How is the Nervous SystemOrganized?

    Chapter 3-Neuroscience:The Brain and Behavior

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    Class Objectives:

    Identify and define the structures ofthe neuron

    Identify and discuss the role ofneurotransmitters on behavior

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    The Neuron

    The neuron is the basic buildingblock of the nervous system

    They are often grouped in bundlescallednerves.

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    4 parts of the neuron

    1. Dendrites are specialized to receive signalsfrom neighboring neurons and carrythem back to the cell body

    Thin, bushy-like structures that receiveinformation from outside the neuron

    Relays the information into the cell body

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    The Neuron

    2. The Cell bodycontains thecell nucleus

    The cell bodyrelays the

    informationdown to theaxon

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    The structure of a neuron

    3. Axon: A thin, long structure that

    transmits signals from the cell body tothe axon terminal.

    4. Axon Terminal is the last step for the relayof information inside the neuron.

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    The cellbody is

    coveredwith AxonTerminals

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    101010

    Once the information hits theterminal, it is transmitted

    outside the cell byneurotransmitters, which reside

    in the axon terminal.

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    111111

    -Electrical Communication-Chemical Communication

    How do NeuronsCommunicate?

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    The Electrical Part

    Action potential is an electrical current

    sent down the axon.

    The activity within the neurons is

    electrical. This current causes theneuron to fire

    This is an all-or-none process

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    Action potentials travel down the axon likea wave of energy

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    Synaptic transmission

    The Synapse is the space between neurons

    The synaptic gap or cleft

    Information must be transmitted acrossthe synapse to other neurons via theneurotransmitters.

    This is an electrochemical process

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    Lets Review!

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    Now, Lets DANCE!

    Time to do the Neuron Dance

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    Presynaptic Neuron

    ________________________

    __________

    ________

    ________

    ____________

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    Neurotransmitters

    Neurotransmitters are chemicalsubstances that reside in the axonterminals

    They communicate to other neurons bybinding to receptors on neighboringneurons

    h

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    Chemical Communication

    The communication between neurons ischemical

    Neurotransmitter are either neutralizedby an enzyme or taken back up by theneuron that released it in reuptake.

    At least 50 different types ofneurotransmitters have been identified

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    Chemical Communication

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    Synaptic Transmission

    The neurotransmitters are released fromthe vesicles and then attach to receptorslocated on the postsynaptic neuron.

    These neurotransmitters are in contactwith the dendrite of the postsynapticneuron only briefly.

    The chemical is almost immediatelydestroyed or reabsorbed

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    Neurotransmitters

    At least 50 different types ofneurotransmitters have been identified

    Acetylcholine GABA

    Serotonin

    Dopamine

    Norepinephrine

    Endorphins

    A l h l

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    Acetylcholine

    Activates motor neurons controllingskeletal muscles

    Contributes to the regulation of attentionarousal and memory

    l f

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    Examples of Neurotransmitters

    Gamma-aminobutyric acid (GABA) isinvolved in experiences of anxiety,alcohol abuse, seizure disorders, andsleep disorders

    Serotonin is involved in sleep andmood regulation and appetite (appetitefor carbohydrates)

    D i

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    Dopamine

    Involved in movement, thoughtprocesses, emotion, feelings of rewardand pleasure

    Implicated in schizophrenia, attentiondeficit disorder, and drug abuse

    N i h i

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    Norepinephrine

    Involved in arousal reactions (increasingheart rate, respiration, sweating, anddilation of pupils)

    May also be involved in hunger, eating,and sexual activity

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    How do drugs effect

    behavior?

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    Drugs Impact on the Brain

    Common drugs can alter the amount of aneurotransmitter released at the synapses

    Some drugs can mimic/facilitate the action ofthe neurotransmitters while others can blockthe action of the neurotransmitter.

    A i A i

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    Agonists versus Antagonists

    Agonists mimic or facilitate the actions of a

    neurotransmitter

    Antagonists oppose/block the actions of aneurotransmitter

    AntagonistAgonist

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    Next Class

    The Brain

    How do the neurons work together?

    The Central Nervous System

    The Peripheral Nervous System