The Mighty MitochondriaThe Mighty Mitochondria

Created By: Mark StudentCreated By: Mark StudentCreated By: Mark StudentCreated By: Mark StudentCopyright © 2010 Intel Corporation. All rights reserved. Adapted with permission. Intel, the Intel logo and the Intel Education Initiative are trademarks of Intel Corporation or its subsidiaries in the U.S. and other countries.*Other names and brands may be claimed as the property of others.

Where Am I Found?Where Am I Found?Where Am I Found?Where Am I Found?

I have my own DNA (mDNA).I have my own DNA (mDNA).I have my own DNA (mDNA).I have my own DNA (mDNA).I am thought to have derived from a I am thought to have derived from a bacteriabacteria--like cell, which incorporated intolike cell, which incorporated intobacteriabacteria like cell, which incorporated into like cell, which incorporated into eukaryotic cells.eukaryotic cells. Eukaryotic cellsEukaryotic cells are cells with membrane are cells with membrane yy

bound organelles (cell parts) that have a bound organelles (cell parts) that have a formal nucleus.formal nucleus.

I f d i k i ll lik lI f d i k i ll lik lI am found in eukaryotic cells, like plant I am found in eukaryotic cells, like plant and animal cells.and animal cells.

Copyright © 2010 Intel Corporation. All rights reserved. Adapted with permission. Intel, the Intel logo and the Intel Education Initiative are trademarks of Intel Corporation or its subsidiaries in the U.S. and other countries.*Other names and brands may be claimed as the property of others.

Animal CellsAnimal CellsAnimal CellsAnimal Cells

Copyright © 2010 Intel Corporation. All rights reserved. Adapted with permission. Intel, the Intel logo and the Intel Education Initiative are trademarks of Intel Corporation or its subsidiaries in the U.S. and other countries.*Other names and brands may be claimed as the property of others.

Plant CellsPlant CellsPlant CellsPlant Cells

Copyright © 2010 Intel Corporation. All rights reserved. Adapted with permission. Intel, the Intel logo and the Intel Education Initiative are trademarks of Intel Corporation or its subsidiaries in the U.S. and other countries.*Other names and brands may be claimed as the property of others.

What Do I Look Like?What Do I Look Like?What Do I Look Like?What Do I Look Like?

(Inner Membrane)C i tCristae

Matrix(Fluid)(Fluid)

Outer Membrane

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I Am the “Powerhouse” of the CellI Am the “Powerhouse” of the CellI Am the Powerhouse of the CellI Am the Powerhouse of the Cell

I supply energy to theI supply energy to theI supply energy to the I supply energy to the cell through the process cell through the process of cellular respiration.of cellular respiration.This occurs in my cristae This occurs in my cristae (inner membrane).(inner membrane).The energy I produce is The energy I produce is in the form of ATP in the form of ATP ( d i( d i(adenosine (adenosine triphosphate).triphosphate).

Copyright © 2010 Intel Corporation. All rights reserved. Adapted with permission. Intel, the Intel logo and the Intel Education Initiative are trademarks of Intel Corporation or its subsidiaries in the U.S. and other countries.*Other names and brands may be claimed as the property of others.

How’s the Energy Formed?How’s the Energy Formed?How s the Energy Formed?How s the Energy Formed?

ATP is formed in electron transport chainATP is formed in electron transport chainATP is formed in electron transport chain.ATP is formed in electron transport chain.The ETC transfers protons (HThe ETC transfers protons (H++) from the ) from the inner compartment to the outerinner compartment to the outerinner compartment to the outer.inner compartment to the outer.As the protons flow back to the inner As the protons flow back to the inner

t t th f th it t th f th icompartment, the energy of their compartment, the energy of their movement is used to add phosphate to movement is used to add phosphate to ADP ( d i di h h t ) f iADP ( d i di h h t ) f iADP (adenosine diphosphate), forming ADP (adenosine diphosphate), forming ATP.ATP.

Copyright © 2010 Intel Corporation. All rights reserved. Adapted with permission. Intel, the Intel logo and the Intel Education Initiative are trademarks of Intel Corporation or its subsidiaries in the U.S. and other countries.*Other names and brands may be claimed as the property of others.

What Does This Look Like?What Does This Look Like?What Does This Look Like? What Does This Look Like? Click here to know more…

H+ H+ H+

cyt cH+

H2

24

4 5

79

Q

2 7

NAD H+

OH- H+OH-

2H+

H+1/2O2

H O1

8

NADH

H2O H2O

H2O

ADP + Pi ATP3 6 10

2 2

Copyright © 2010 Intel Corporation. All rights reserved. Adapted with permission. Intel, the Intel logo and the Intel Education Initiative are trademarks of Intel Corporation or its subsidiaries in the U.S. and other countries.*Other names and brands may be claimed as the property of others.

Without the MitochondriaWithout the MitochondriaWithout the Mitochondria…Without the Mitochondria…

Cells wouldn’t have enough energy toCells wouldn’t have enough energy toCells wouldn t have enough energy to Cells wouldn t have enough energy to survive.survive.

Cardiac CellsCopyright © 2010 Intel Corporation. All rights reserved. Adapted with permission. Intel, the Intel logo and the Intel Education Initiative are trademarks of Intel Corporation or its subsidiaries in the U.S. and other countries.*Other names and brands may be claimed as the property of others.

When Your Cells DieWhen Your Cells DieWhen Your Cells Die…When Your Cells Die…

Tissues dieTissues dieTissues die.Tissues die.

Cardiac TissueCopyright © 2010 Intel Corporation. All rights reserved. Adapted with permission. Intel, the Intel logo and the Intel Education Initiative are trademarks of Intel Corporation or its subsidiaries in the U.S. and other countries.*Other names and brands may be claimed as the property of others.

When Tissues DieWhen Tissues DieWhen Tissues Die…When Tissues Die…

Organs failOrgans failOrgans fail.Organs fail.

Example: The Heart stops beating.

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Without Your Organs FunctioningWithout Your Organs FunctioningWithout Your Organs Functioning…Without Your Organs Functioning…

You’ll keel over and dieYou’ll keel over and dieYou ll keel over and die.You ll keel over and die.

If only I had enough energy to stay on the wall!

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So Why Am I Important?So Why Am I Important?So Why Am I Important?So Why Am I Important?

It’s all connectedIt’s all connectedIt s all connected.It s all connected.If one level fails, all levels fail.If one level fails, all levels fail.Y ’ d f t th tY ’ d f t th tYou’re made of organ systems that are You’re made of organ systems that are made of organs that are made of tissues made of organs that are made of tissues th t d f ll th t d fth t d f ll th t d fthat are made of cells that are made of that are made of cells that are made of organelles like me, the “Mighty organelles like me, the “Mighty Mit h d i ” If I f il f il h ld IMit h d i ” If I f il f il h ld IMitochondria.” If I fail, you fail, or should I Mitochondria.” If I fail, you fail, or should I say, say, diedie!!

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Works CitedWorks CitedWorks CitedWorks Cited

Microsoft Office ClipArtMicrosoft Office ClipArtMicrosoft Office ClipArtMicrosoft Office ClipArthttp://office.microsoft.com/clipart/default.aspx?lchttp://office.microsoft.com/clipart/default.aspx?lc

=en=en--ususenen ususStructure and Function in Cell BiologyStructure and Function in Cell Biologyhttp://darwin nmsu edu/ molbio/cell/Organelle hhttp://darwin nmsu edu/ molbio/cell/Organelle hhttp://darwin.nmsu.edu/~molbio/cell/Organelle.hhttp://darwin.nmsu.edu/~molbio/cell/Organelle.h

tmltmlThe Biology Project: Cell BiologyThe Biology Project: Cell BiologyThe Biology Project: Cell BiologyThe Biology Project: Cell Biologywww.biology.arizona.edu/cell_bio/cell_bio.htmlwww.biology.arizona.edu/cell_bio/cell_bio.html

Copyright © 2010 Intel Corporation. All rights reserved. Adapted with permission. Intel, the Intel logo and the Intel Education Initiative are trademarks of Intel Corporation or its subsidiaries in the U.S. and other countries.*Other names and brands may be claimed as the property of others.