The Many Measures of Accuracy: How Are They Related? Matt Spangler, Ph.D. University of...

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The Many Measures of The Many Measures of Accuracy: How Are They Accuracy: How Are They Related? Related? Matt Spangler, Ph.D. University of Nebraska-Lincoln

Transcript of The Many Measures of Accuracy: How Are They Related? Matt Spangler, Ph.D. University of...

Page 1: The Many Measures of Accuracy: How Are They Related? Matt Spangler, Ph.D. University of Nebraska-Lincoln.

The Many Measures of The Many Measures of Accuracy: How Are They Accuracy: How Are They

Related?Related?Matt Spangler, Ph.D.

University of Nebraska-Lincoln

Page 2: The Many Measures of Accuracy: How Are They Related? Matt Spangler, Ph.D. University of Nebraska-Lincoln.

Why Worry About Accuracy?Why Worry About Accuracy?

“Prediction is hard, especially about the future”

Page 3: The Many Measures of Accuracy: How Are They Related? Matt Spangler, Ph.D. University of Nebraska-Lincoln.

WebsterWebster

Freedom from mistake or errorConformity to truth or to a standard or

modelDegree of conformity of a measure to a

standard or true value

Page 4: The Many Measures of Accuracy: How Are They Related? Matt Spangler, Ph.D. University of Nebraska-Lincoln.

Static?Static?

Yearling EPD of +100 for YW◦+100 after 50 progeny?

Page 5: The Many Measures of Accuracy: How Are They Related? Matt Spangler, Ph.D. University of Nebraska-Lincoln.

Values are standard deviationsLow accuracy means larger possible

change valuesNot static

◦Different for each breed, trait, and could differ between evaluations

Possible ChangePossible Change

Page 6: The Many Measures of Accuracy: How Are They Related? Matt Spangler, Ph.D. University of Nebraska-Lincoln.

Possible Change TablePossible Change Table

Page 7: The Many Measures of Accuracy: How Are They Related? Matt Spangler, Ph.D. University of Nebraska-Lincoln.

How to Use Possible ChangeHow to Use Possible Change

Weaning Wt. EPD = 40ACC. = 0.60

Possible change +/- 4.60

68% confident his true EPD is between 35.4 and 44.6

Page 8: The Many Measures of Accuracy: How Are They Related? Matt Spangler, Ph.D. University of Nebraska-Lincoln.

25 30 35 40 45 50 550

0.01

0.02

0.03

0.04

0.05

0.06

0.07

0.08

0.09

68%

95%

Confidence Intervals for EPD = 40, Acc = 0.60, SEP = 4.6

Page 9: The Many Measures of Accuracy: How Are They Related? Matt Spangler, Ph.D. University of Nebraska-Lincoln.

Mating—Passing of AllelesMating—Passing of Alleles

Page 10: The Many Measures of Accuracy: How Are They Related? Matt Spangler, Ph.D. University of Nebraska-Lincoln.

Why the low correlations (accuracy) for yearling bulls?

Uncertainty surrounding what alleles were received from parents

We begin to understand this when an animal has a record

Becomes more clear as we see what it is passing on to its offspring

Commercial producers do not have this luxury

Mendelian SamplingMendelian Sampling

Page 11: The Many Measures of Accuracy: How Are They Related? Matt Spangler, Ph.D. University of Nebraska-Lincoln.

Two yearling bulls with a +5 CED EPD with accuracy of 0.2.◦Possible change of 6

With the addition of more information their EPDs change

One favorably and the other unfavorablyMore information earlier allows you to

choose animals more accurately

Calving EaseCalving Ease

Page 12: The Many Measures of Accuracy: How Are They Related? Matt Spangler, Ph.D. University of Nebraska-Lincoln.

Bull A Bull B◦+5 +5

Addition of progeny information

Bull A Bull B◦-1 +11

In this extreme case risk was 12% more calving difficulties

Average is still +5*

Example-CEDExample-CED

Page 13: The Many Measures of Accuracy: How Are They Related? Matt Spangler, Ph.D. University of Nebraska-Lincoln.

BIF AccuracyBIF Accuracy

More conservative◦More progeny to get higher values

The U.S. standardRange from 0-1

Page 14: The Many Measures of Accuracy: How Are They Related? Matt Spangler, Ph.D. University of Nebraska-Lincoln.

True AccuracyTrue Accuracy

Correlation between predicted and “true” breeding values

r nh2

4(n 1)h2

Page 15: The Many Measures of Accuracy: How Are They Related? Matt Spangler, Ph.D. University of Nebraska-Lincoln.

Relationship to BIFRelationship to BIF

r 1 (1 BIF)2

Page 16: The Many Measures of Accuracy: How Are They Related? Matt Spangler, Ph.D. University of Nebraska-Lincoln.

Accuracy ComparedAccuracy Compared

Page 17: The Many Measures of Accuracy: How Are They Related? Matt Spangler, Ph.D. University of Nebraska-Lincoln.

Genetic Variation ExplainedGenetic Variation Explained

The proportion of variation due to additive genetics of a single trait explained (by a genomic test)

Range between 0 and 100%

A test explains 49% of the GV for a trait…

Page 18: The Many Measures of Accuracy: How Are They Related? Matt Spangler, Ph.D. University of Nebraska-Lincoln.

MBV BIF AccuracyMBV BIF Accuracy

Genetic Correlation BIF Accuracy

0.1 0.005

0.2 0.020

0.3 0.046

0.4 0.083

0.5 0.132

0.6 0.2

0.7 0.286

Page 19: The Many Measures of Accuracy: How Are They Related? Matt Spangler, Ph.D. University of Nebraska-Lincoln.

TestTest

BW EPD -1.0 with accuracy (BIF) of .9050K Prediction for BW explaining 50% GV

Page 20: The Many Measures of Accuracy: How Are They Related? Matt Spangler, Ph.D. University of Nebraska-Lincoln.

What To Use?--GeneticsWhat To Use?--Genetics

Any of the measures described can be used

But not directly comparedEasiest if they were on the same scale

Page 21: The Many Measures of Accuracy: How Are They Related? Matt Spangler, Ph.D. University of Nebraska-Lincoln.

What To Use--ManagementWhat To Use--Management

Different ball of waxInterested in proportion of phenotypic

variation explainedNo metrics available to do this

Page 22: The Many Measures of Accuracy: How Are They Related? Matt Spangler, Ph.D. University of Nebraska-Lincoln.

Relative Ranking Of MeasuresRelative Ranking Of Measures

Page 23: The Many Measures of Accuracy: How Are They Related? Matt Spangler, Ph.D. University of Nebraska-Lincoln.

Reducing RiskReducing Risk

Accuracy is importantNot much difference between yearling

bullsMA-EPD could create differencesBull buyers will have to look at accuracyAccuracy helps determine the “benefit”

Page 24: The Many Measures of Accuracy: How Are They Related? Matt Spangler, Ph.D. University of Nebraska-Lincoln.

It Doesn’t Work…It Doesn’t Work…

“I’ve used high accuracy calving ease bulls and had big calves”

Environment?Cow?Within sire variation?

Page 25: The Many Measures of Accuracy: How Are They Related? Matt Spangler, Ph.D. University of Nebraska-Lincoln.

Take HomeTake Home

Pay attention to accuracyThere are different measures

◦They are not “apples to apples”Right now you have to do the mathYou need to know how to equate BIF

accuracy to %GVIf a sire has a high accuracy then

additional information does very little

Page 26: The Many Measures of Accuracy: How Are They Related? Matt Spangler, Ph.D. University of Nebraska-Lincoln.

Questions?Questions?