The long-term cost-effectiveness of cardiac resynchronization therapy with or without an implantable...

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The long-term cost-effectiveness of cardiac resynchronization therapy with or without an implantable cardioverter-defibrillator by Guiqing Yao, Nick Freemantle, Melanie J. Calvert, Stirling Bryan, Jean-Claude Daubert, and John G.F. Cleland EHJ Volume 28(1):42-51 January 12, 2007 © The European Society of Cardiology 2006. All rights reserved. For Permissions, please e-mail: [email protected]

Transcript of The long-term cost-effectiveness of cardiac resynchronization therapy with or without an implantable...

Page 1: The long-term cost-effectiveness of cardiac resynchronization therapy with or without an implantable cardioverter-defibrillator by Guiqing Yao, Nick Freemantle,

The long-term cost-effectiveness of cardiac resynchronization therapy with or without an implantable

cardioverter-defibrillator

by Guiqing Yao, Nick Freemantle, Melanie J. Calvert, Stirling Bryan, Jean-Claude Daubert, and John G.F. Cleland

EHJVolume 28(1):42-51January 12, 2007

© The European Society of Cardiology 2006. All rights reserved. For Permissions, please e-mail: [email protected]

Page 2: The long-term cost-effectiveness of cardiac resynchronization therapy with or without an implantable cardioverter-defibrillator by Guiqing Yao, Nick Freemantle,

Structure of short term model.

Guiqing Yao et al. Eur Heart J 2007;28:42-51

© The European Society of Cardiology 2006. All rights reserved. For Permissions, please e-mail: [email protected]

Page 3: The long-term cost-effectiveness of cardiac resynchronization therapy with or without an implantable cardioverter-defibrillator by Guiqing Yao, Nick Freemantle,

Structure of long-term model (NYHA class I).

Guiqing Yao et al. Eur Heart J 2007;28:42-51

© The European Society of Cardiology 2006. All rights reserved. For Permissions, please e-mail: [email protected]

Page 4: The long-term cost-effectiveness of cardiac resynchronization therapy with or without an implantable cardioverter-defibrillator by Guiqing Yao, Nick Freemantle,

Model predicted survival curves for MT, CRT-P, and CRT–ICD.

Guiqing Yao et al. Eur Heart J 2007;28:42-51

© The European Society of Cardiology 2006. All rights reserved. For Permissions, please e-mail: [email protected]

Page 5: The long-term cost-effectiveness of cardiac resynchronization therapy with or without an implantable cardioverter-defibrillator by Guiqing Yao, Nick Freemantle,

(A) Cost-effectiveness acceptability curves of CRT (+/ − ICD) vs.

Guiqing Yao et al. Eur Heart J 2007;28:42-51

© The European Society of Cardiology 2006. All rights reserved. For Permissions, please e-mail: [email protected]

Page 6: The long-term cost-effectiveness of cardiac resynchronization therapy with or without an implantable cardioverter-defibrillator by Guiqing Yao, Nick Freemantle,

Incremental cost per QALY gained by different starting age at treatment (in EUROs).

Guiqing Yao et al. Eur Heart J 2007;28:42-51

© The European Society of Cardiology 2006. All rights reserved. For Permissions, please e-mail: [email protected]

Page 7: The long-term cost-effectiveness of cardiac resynchronization therapy with or without an implantable cardioverter-defibrillator by Guiqing Yao, Nick Freemantle,

Model predicting survival with the CARE-HF trial age matched cohort and the trial based Kaplan–Meier estimates of survival curves.

Guiqing Yao et al. Eur Heart J 2007;28:42-51

© The European Society of Cardiology 2006. All rights reserved. For Permissions, please e-mail: [email protected]