The Endocrine System

The Pituitary

Low magnification – the entire Pituitary Gland

Posterior Pituitary Pars Intermedia Anterior Pituitary

Pars TuberalisPituitary Stalk

High mag of the Anterior Pituitary – note eosinophilic and basophilic cells

Growth Hormone ACTH

Immunohistochemictry of the Anterior Pituitary

TEM of the Anterior Pituitary – note different granule morphology

C – corticotrophs (ACTH); G – gonadotrophs (FSH,LH) S – somatotrophs (growth hormone); T Thyrotrophs (TSH) ; F – fenestrated capillary

High mag of the Posterior Pituitary – neurons, capillaries, and pituicytes

High mag of the Posterior Pituitary – note Herring Bodies (arrow)

TEM of the Posterior Pituitary UN -unmyelinated neuron; asterisks – Herring Body

The Thyroid & Parathyroids

High mag of thyroid follicles – note Parafollicular or C-Cells (arrows)

Low Magnification of the Parathyroid Gland

Parathyroid Gland – note small dark staining chief cells and larger, eosinophilic oxyphil cells

The Adrenal Glands

Low magnification of the Adrenal Gland

Medulla

Cortex

Cortex

Adrenal Cortex

Zona Glomerulosa

Zona Fasciculata

Zona Reticularis

Adrenal Cortex

Zona Glomerulosa

(clumps, cords, and follicle like structures

Zona Fasciculata

(cords of spongiocytes)

Adrenal Gland

Zona Fasciculata

cords of spongiocytes

Zona Reticularis

darker staining cells

Adrenal Medulla

The Islets of Langerhan

Low magnification of the Pancreas with Islets of Langerhans (arrows)

High mag of an Islet – note Beta cells and more eosinophilic Alpha2 cells

Acini

Alpha Cells

Glucagon Insulin

Immunohistochemistry of a pancrearic Islet of Langerhans

Pineal Body

The Seat of the Soul

The Third Eye

Pineal Gland

N – neuroglia

P –pinealocytes

S – Brain Sand