The Elephant in the Room 25 minutes.pdf · The Adverse Childhood Experiences (ACE) Study Examines...

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Adverse Childhood Experiences and Chronic Disease: The Elephant in the Room Robert Anda, MD, MS www.cdc.gov/ace www.acestudy.org

Transcript of The Elephant in the Room 25 minutes.pdf · The Adverse Childhood Experiences (ACE) Study Examines...

Page 1: The Elephant in the Room 25 minutes.pdf · The Adverse Childhood Experiences (ACE) Study Examines the health and social effects of ACEs throughout the lifespan among 17,421 members

Adverse Childhood Experiences andChronic Disease:

The Elephant in the Room

Robert Anda, MD, MS

www.cdc.gov/ace

www.acestudy.org

Page 2: The Elephant in the Room 25 minutes.pdf · The Adverse Childhood Experiences (ACE) Study Examines the health and social effects of ACEs throughout the lifespan among 17,421 members

The Walk toParadise Garden

W. Eugene Smith

Page 3: The Elephant in the Room 25 minutes.pdf · The Adverse Childhood Experiences (ACE) Study Examines the health and social effects of ACEs throughout the lifespan among 17,421 members

Unpredictable PredictableSevere Moderate

Number of EpisodesChronicity*

ResilienceVulnerability

(Poly)geneticsEpigenetics Intrauterine

exposures*

Stress(adrenaline, cortisol)

Page 4: The Elephant in the Room 25 minutes.pdf · The Adverse Childhood Experiences (ACE) Study Examines the health and social effects of ACEs throughout the lifespan among 17,421 members
Page 5: The Elephant in the Room 25 minutes.pdf · The Adverse Childhood Experiences (ACE) Study Examines the health and social effects of ACEs throughout the lifespan among 17,421 members
Page 6: The Elephant in the Room 25 minutes.pdf · The Adverse Childhood Experiences (ACE) Study Examines the health and social effects of ACEs throughout the lifespan among 17,421 members
Page 7: The Elephant in the Room 25 minutes.pdf · The Adverse Childhood Experiences (ACE) Study Examines the health and social effects of ACEs throughout the lifespan among 17,421 members
Page 8: The Elephant in the Room 25 minutes.pdf · The Adverse Childhood Experiences (ACE) Study Examines the health and social effects of ACEs throughout the lifespan among 17,421 members
Page 9: The Elephant in the Room 25 minutes.pdf · The Adverse Childhood Experiences (ACE) Study Examines the health and social effects of ACEs throughout the lifespan among 17,421 members

The Adverse Childhood Experiences (ACE) Study

Examines the health and social effects of ACEsthroughout the lifespan among 17,421 membersof the Kaiser Health Plan in San Diego County

A Primary Care Setting…Educated…

Middle Class..Predominantly White…

Page 10: The Elephant in the Room 25 minutes.pdf · The Adverse Childhood Experiences (ACE) Study Examines the health and social effects of ACEs throughout the lifespan among 17,421 members

Adverse Childhood Experiences Are Common

Substance abuse 27%Parental sep/divorce 23%Mental illness 17%Battered mother 13%Criminal behavior 6%

Household dysfunction:

Abuse:Psychological 11%Physical 28%Sexual 21%

Neglect:Emotional 15%Physical 10%

Page 11: The Elephant in the Room 25 minutes.pdf · The Adverse Childhood Experiences (ACE) Study Examines the health and social effects of ACEs throughout the lifespan among 17,421 members

Adverse Childhood Experiences Rarely Occur in Isolation…

They come in groups.

Page 12: The Elephant in the Room 25 minutes.pdf · The Adverse Childhood Experiences (ACE) Study Examines the health and social effects of ACEs throughout the lifespan among 17,421 members

ACEs tend to come in groups…

Additional ACEs (%)1 2 3 4 >5

If you had:A battered mother 95 82 64 48 52

Page 13: The Elephant in the Room 25 minutes.pdf · The Adverse Childhood Experiences (ACE) Study Examines the health and social effects of ACEs throughout the lifespan among 17,421 members

Adverse Childhood Experiences ScoreBiologic Stress “Dose”

ACE Score Prevalence0 33%1 26%2 16%3 10%

4 or more 16%

Page 14: The Elephant in the Room 25 minutes.pdf · The Adverse Childhood Experiences (ACE) Study Examines the health and social effects of ACEs throughout the lifespan among 17,421 members

0

2

4

6

8

10

12

14

16

18

20

Perc

ent W

ith H

ealth

Pro

blem

(%

) 0 1 2 3 4 or moreACE Score

Early smokinginitiation

Current smoking COPD

ACEs, Smoking, and Lung Disease

Page 15: The Elephant in the Room 25 minutes.pdf · The Adverse Childhood Experiences (ACE) Study Examines the health and social effects of ACEs throughout the lifespan among 17,421 members

ACE Score and HIV Risks

0

2

4

6

8

10

12

14

16

18

20

Perc

ent W

ith H

ealth

Pro

blem

(%

)

0 1 2 3 4 or moreACE Score

Ever InjectedDrugs

Had 50 or MoreIntercourse Partners

Ever Had anSTD

Page 16: The Elephant in the Room 25 minutes.pdf · The Adverse Childhood Experiences (ACE) Study Examines the health and social effects of ACEs throughout the lifespan among 17,421 members

The ACE Score…Alcohol Use and Abuse

0

5

10

15

20

25

30

35

40

0 1 2 3 4 or moreACE Score

Alcoholic Married anAlcoholic

Perc

ent w

ith a

lcoh

ol

rela

ted

prob

lem

Page 17: The Elephant in the Room 25 minutes.pdf · The Adverse Childhood Experiences (ACE) Study Examines the health and social effects of ACEs throughout the lifespan among 17,421 members

A Focus on Mental Health…

Page 18: The Elephant in the Room 25 minutes.pdf · The Adverse Childhood Experiences (ACE) Study Examines the health and social effects of ACEs throughout the lifespan among 17,421 members

The ACE Score and a Lifetime History of Depression

0

10

20

30

40

50

60

70

0 1 2 3 >=4

Women Men

ACE Score

Perc

ent

depr

esse

d (%

)

Page 19: The Elephant in the Room 25 minutes.pdf · The Adverse Childhood Experiences (ACE) Study Examines the health and social effects of ACEs throughout the lifespan among 17,421 members

The ACE Score and the Prevalence of Attempted Suicide

0

5

10

15

20

0 1 2 3 >=4

ACE Score

Perc

ent

atem

pted

(%

)

Page 20: The Elephant in the Room 25 minutes.pdf · The Adverse Childhood Experiences (ACE) Study Examines the health and social effects of ACEs throughout the lifespan among 17,421 members

Leading Causes of Death…

Page 21: The Elephant in the Room 25 minutes.pdf · The Adverse Childhood Experiences (ACE) Study Examines the health and social effects of ACEs throughout the lifespan among 17,421 members

The ACE Score and the Prevalence of Coronary Heart Disease

0

1

2

3

4

5

6

0 1 2 3 >=4

ACE Score

Perc

ent

(%)

Page 22: The Elephant in the Room 25 minutes.pdf · The Adverse Childhood Experiences (ACE) Study Examines the health and social effects of ACEs throughout the lifespan among 17,421 members

Adverse Childhood ExperiencesAs a National Health Issue

ACEs have a strong influence on:-adolescent health

-reproductive health-smoking

-alcohol abuse-illicit drug abuse-sexual behavior

-mental health- risk of revictimization

-stability of relationships-performance in the workforce

Page 23: The Elephant in the Room 25 minutes.pdf · The Adverse Childhood Experiences (ACE) Study Examines the health and social effects of ACEs throughout the lifespan among 17,421 members

Adverse Childhood ExperiencesAs a National Health Issue

ACEs increase the risk of:-Early Death

-Heart disease-Lung cancer

- Chronic Lung disease- Liver disease

- Suicide- Injuries

-HIV and STDs-Autoimmune Disease

Page 24: The Elephant in the Room 25 minutes.pdf · The Adverse Childhood Experiences (ACE) Study Examines the health and social effects of ACEs throughout the lifespan among 17,421 members

No data

Source: Behavioral Risk Factor Surveillance System, CDC.

2009

6 States

States With ACE Studiesin 2009

Page 25: The Elephant in the Room 25 minutes.pdf · The Adverse Childhood Experiences (ACE) Study Examines the health and social effects of ACEs throughout the lifespan among 17,421 members

No data

Source: Behavioral Risk Factor Surveillance System, CDC.

20102009

13 States

States With ACE Studiesin 2009-2010

Page 26: The Elephant in the Room 25 minutes.pdf · The Adverse Childhood Experiences (ACE) Study Examines the health and social effects of ACEs throughout the lifespan among 17,421 members

Source: Behavioral Risk Factor Surveillance System, CDC.

No data 20102009 2011

18 States

States With ACE Studiesin 2009-2011

Page 27: The Elephant in the Room 25 minutes.pdf · The Adverse Childhood Experiences (ACE) Study Examines the health and social effects of ACEs throughout the lifespan among 17,421 members

Source: Behavioral Risk Factor Surveillance System, CDC.

No data 20102009 2011

19 States

States With ACE Studies2009-2012

2012

Page 28: The Elephant in the Room 25 minutes.pdf · The Adverse Childhood Experiences (ACE) Study Examines the health and social effects of ACEs throughout the lifespan among 17,421 members

Beham, (Hans) Sebald (1500-1550): Hercules slaying the Hydra, 1545 from The Labours of Hercules (1542-1548).

Page 29: The Elephant in the Room 25 minutes.pdf · The Adverse Childhood Experiences (ACE) Study Examines the health and social effects of ACEs throughout the lifespan among 17,421 members

The Walk toParadise Garden

W. Eugene Smith

Page 30: The Elephant in the Room 25 minutes.pdf · The Adverse Childhood Experiences (ACE) Study Examines the health and social effects of ACEs throughout the lifespan among 17,421 members

“The Creation of Adam”Michelangelo 1508-1512

Page 31: The Elephant in the Room 25 minutes.pdf · The Adverse Childhood Experiences (ACE) Study Examines the health and social effects of ACEs throughout the lifespan among 17,421 members

Treatment

Education  Prevention

All must considerIntergenerational transmission

A Public Health Framework For Change

Page 32: The Elephant in the Room 25 minutes.pdf · The Adverse Childhood Experiences (ACE) Study Examines the health and social effects of ACEs throughout the lifespan among 17,421 members

Limits of Understanding

by Paul Klee (1879-1940)