The Cell Cycle Year 12 Biology C9. Draw a circle to the left hand side of the page.

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The Cell Cycle Year 12 Biology C9

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Divide the circle into four sections

Transcript of The Cell Cycle Year 12 Biology C9. Draw a circle to the left hand side of the page.

Page 1: The Cell Cycle Year 12 Biology C9. Draw a circle to the left hand side of the page.

The Cell Cycle

Year 12 Biology C9

Page 2: The Cell Cycle Year 12 Biology C9. Draw a circle to the left hand side of the page.

Draw a circle to the left hand side of the page

Page 3: The Cell Cycle Year 12 Biology C9. Draw a circle to the left hand side of the page.

Divide the circle into four sections

Page 4: The Cell Cycle Year 12 Biology C9. Draw a circle to the left hand side of the page.

Divide the right-hand quarter into fourths.

Page 5: The Cell Cycle Year 12 Biology C9. Draw a circle to the left hand side of the page.

Label the quarters

G1 Phase

S Phase

G2 Phase

M

Phase

Page 6: The Cell Cycle Year 12 Biology C9. Draw a circle to the left hand side of the page.

Label the phases of M-phase (Mitosis)

G1 Phase

S Phase

G2 Phase

M

Phase

Prophase

Metaphase

AnaphaseTelophase

Page 7: The Cell Cycle Year 12 Biology C9. Draw a circle to the left hand side of the page.

Add details of each phase of mitosis.

G1 Phase

S Phase

G2 Phase

Prophase

Metaphase

AnaphaseTelophase

Page 8: The Cell Cycle Year 12 Biology C9. Draw a circle to the left hand side of the page.

Add details of each phase of mitosis.

G1 Phase

S Phase

G2 Phase

Prophase

Metaphase

AnaphaseTelophase

Page 9: The Cell Cycle Year 12 Biology C9. Draw a circle to the left hand side of the page.

Add details of each phase of mitosis.

G1 Phase

S Phase

G2 Phase

Prophase

Metaphase

AnaphaseTelophase

Page 10: The Cell Cycle Year 12 Biology C9. Draw a circle to the left hand side of the page.

Add details of each phase of mitosis.

G1 Phase

S Phase

G2 Phase

Prophase

Metaphase

AnaphaseTelophase

Page 11: The Cell Cycle Year 12 Biology C9. Draw a circle to the left hand side of the page.
Page 12: The Cell Cycle Year 12 Biology C9. Draw a circle to the left hand side of the page.

Add details of each phase of the cell cycle

G1 Phase

S Phase

G2 Phase

Prophase

Metaphase

AnaphaseTelophase

Page 13: The Cell Cycle Year 12 Biology C9. Draw a circle to the left hand side of the page.

Add details of each phase of the cell cycle

G1 Phase

S Phase

G2 Phase

Prophase

Metaphase

AnaphaseTelophase

Cell growth

Energy

Organelles

Page 14: The Cell Cycle Year 12 Biology C9. Draw a circle to the left hand side of the page.

Add details of each phase of the cell cycle

G1 Phase

S Phase

G2 Phase

Prophase

Metaphase

AnaphaseTelophase

Cell growth

Energy

Organelles

DNA Synthesis

Page 15: The Cell Cycle Year 12 Biology C9. Draw a circle to the left hand side of the page.

Add details of each phase of the cell cycle

G1 Phase

S Phase

G2 Phase

Prophase

Metaphase

AnaphaseTelophase

Cell growth

Energy

Organelles

DNA Synthesis

Cell Growth

Energy

Page 16: The Cell Cycle Year 12 Biology C9. Draw a circle to the left hand side of the page.

Add checkpoints

G1 Phase

S Phase

G2 Phase

Prophase

Metaphase

AnaphaseTelophase

Cell growth

Energy

Organelles

DNA Synthesis

Cell Growth

Energy

Check for DNA Damage

Cell big enough?

Page 17: The Cell Cycle Year 12 Biology C9. Draw a circle to the left hand side of the page.

Add checkpoints

G1 Phase

S Phase

G2 Phase

Prophase

Metaphase

AnaphaseTelophase

Cell growth

Energy

Organelles

DNA Synthesis

Cell Growth

Energy

Check for DNA SynthesisCell size

Check for DNA Damage

Cell big enough?

Page 18: The Cell Cycle Year 12 Biology C9. Draw a circle to the left hand side of the page.

Add checkpoints

G1 Phase

S Phase

G2 Phase

Prophase

Metaphase

AnaphaseTelophase

Cell growth

Energy

Organelles

DNA Synthesis

Cell Growth

Energy

Check for DNA SynthesisCell size

Check for DNA Damage

Cell big enough?

Page 19: The Cell Cycle Year 12 Biology C9. Draw a circle to the left hand side of the page.

Add checkpoints

G1 Phase

S Phase

G2 Phase

Prophase

Metaphase

AnaphaseTelophase

Cell growth

Energy

Organelles

DNA Synthesis

Cell Growth

Energy

Check for DNA SynthesisCell size

Hold to break down cyclins

Check for DNA Damage

Cell big enough?

Page 20: The Cell Cycle Year 12 Biology C9. Draw a circle to the left hand side of the page.

Add checkpoints

G1 Phase

S Phase

G2 Phase

Prophase

Metaphase

AnaphaseTelophase

Cell growth

Energy

Organelles

DNA Synthesis

Cell Growth

Energy

Check for DNA SynthesisCell size

Pause to break down cyclins

Check for DNA Damage

Cell big enough?

Page 21: The Cell Cycle Year 12 Biology C9. Draw a circle to the left hand side of the page.

Add checkpoints

G1 Phase

S Phase

G2 Phase

Prophase

Metaphase

AnaphaseTelophase

Cell growth

Energy

Organelles

DNA Synthesis

Cell Growth

Energy

Check for DNA SynthesisCell size

Pause to break down cyclins

Check for DNA Damage

Cell big enough?

Page 22: The Cell Cycle Year 12 Biology C9. Draw a circle to the left hand side of the page.

Add external growth factors…

G1 Phase

S Phase

G2 Phase

Prophase

Metaphase

AnaphaseTelophase

Cell growth

Energy

Organelles

DNA Synthesis

Cell Growth

Energy

Mitosis promoting factor (e.g. hormone)

Nucleus

Page 23: The Cell Cycle Year 12 Biology C9. Draw a circle to the left hand side of the page.

Nucleus makes internal regulators..

G1 Phase

S Phase

G2 Phase

Prophase

Metaphase

AnaphaseTelophase

Cell growth

Energy

Organelles

DNA Synthesis

Cell Growth

Energy

Mitosis promoting factor (e.g. hormone)

Nucleus

Kinase Cyclin

Page 24: The Cell Cycle Year 12 Biology C9. Draw a circle to the left hand side of the page.

Nucleus makes internal regulators..

G1 Phase

S Phase

G2 Phase

Prophase

Metaphase

AnaphaseTelophase

Cell growth

Energy

Organelles

DNA Synthesis

Cell Growth

Energy

Mitosis promoting factor (e.g. hormone)

Nucleus

CDK complex

Page 25: The Cell Cycle Year 12 Biology C9. Draw a circle to the left hand side of the page.

CDKs build up…

G1 Phase

S Phase

G2 Phase

Prophase

Metaphase

AnaphaseTelophase

Cell growth

Energy

Organelles

DNA Synthesis

Cell Growth

Energy

CDK complex

Page 26: The Cell Cycle Year 12 Biology C9. Draw a circle to the left hand side of the page.

CDKs build up…

G1 Phase

S Phase

G2 Phase

Prophase

Metaphase

AnaphaseTelophase

Cell growth

Energy

Organelles

DNA Synthesis

Cell Growth

Energy

CDK complex

Page 27: The Cell Cycle Year 12 Biology C9. Draw a circle to the left hand side of the page.

CDKs build up…

G1 Phase

S Phase

G2 Phase

Prophase

Metaphase

AnaphaseTelophase

Cell growth

Energy

Organelles

DNA Synthesis

Cell Growth

Energy

CDK complex

Page 28: The Cell Cycle Year 12 Biology C9. Draw a circle to the left hand side of the page.

CDKs build up…

G1 Phase

S Phase

G2 Phase

Prophase

Metaphase

AnaphaseTelophase

Cell growth

Energy

Organelles

DNA Synthesis

Cell Growth

Energy

CDK complex

Page 29: The Cell Cycle Year 12 Biology C9. Draw a circle to the left hand side of the page.

CDKs build up…

G1 Phase

S Phase

G2 Phase

Prophase

Metaphase

AnaphaseTelophase

Cell growth

Energy

Organelles

DNA Synthesis

Cell Growth

Energy

CDK complex

Page 30: The Cell Cycle Year 12 Biology C9. Draw a circle to the left hand side of the page.

CDKs start to break down…

G1 Phase

S Phase

G2 Phase

Prophase

Metaphase

AnaphaseTelophase

Cell growth

Energy

Organelles

DNA Synthesis

Cell Growth

Energy

CDK complex

Page 31: The Cell Cycle Year 12 Biology C9. Draw a circle to the left hand side of the page.

CDKs start to break down…

G1 Phase

S Phase

G2 Phase

Prophase

Metaphase

AnaphaseTelophase

Cell growth

Energy

Organelles

DNA Synthesis

Cell Growth

Energy

CDK complex

Page 32: The Cell Cycle Year 12 Biology C9. Draw a circle to the left hand side of the page.

Only when all CDK has broken down can the cell proceed to Metaphase…

G1 Phase

S Phase

G2 Phase

Prophase

Metaphase

AnaphaseTelophase

Cell growth

Energy

Organelles

DNA Synthesis

Cell Growth

Energy

Page 33: The Cell Cycle Year 12 Biology C9. Draw a circle to the left hand side of the page.

G1 Phase

S Phase

G2 Phase

Prophase

Metaphase

AnaphaseTelophase

Cell growth

Energy

Organelles

DNA Synthesis

Cell Growth

Energy

Only when all CDK has broken down can the cell proceed to Metaphase…

Page 34: The Cell Cycle Year 12 Biology C9. Draw a circle to the left hand side of the page.

G1 Phase

S Phase

G2 Phase

Prophase

Metaphase

AnaphaseTelophase

Cell growth

Energy

Organelles

DNA Synthesis

Cell Growth

Energy

G0 phase

At telophase the cell can go into G0 phase (and remain there) or continue on to the cell cycle…

Page 35: The Cell Cycle Year 12 Biology C9. Draw a circle to the left hand side of the page.

G1 Phase

S Phase

G2 Phase

Prophase

Metaphase

AnaphaseTelophase

Cell growth

Energy

Organelles

DNA Synthesis

Cell Growth

Energy

G0 phase

Differentiation

The cell may then become differentiated into any one of the 200 body cells in humans..

Page 36: The Cell Cycle Year 12 Biology C9. Draw a circle to the left hand side of the page.

Role of inhibitors…•p27blocks the build up of CDK complex during G1 and prevents movement to S phase

G1 Phase

S Phase

G2 Phase

Prophase

Metaphase

AnaphaseTelophase

Cell growth

Energy

Organelles

DNA Synthesis

Cell Growth

Energy

CDK complexp27

Page 37: The Cell Cycle Year 12 Biology C9. Draw a circle to the left hand side of the page.

Role of inhibitors…•p27blocks the build up of CDK complex during G1 and prevents movement to S phase•p53 stops cell cycle at any point if DNA is damaged.

G1 Phase

S Phase

G2 Phase

Prophase

Metaphase

AnaphaseTelophase

Cell growth

Energy

Organelles

DNA Synthesis

Cell Growth

Energy

CDK complexp53

p53

p53

Page 38: The Cell Cycle Year 12 Biology C9. Draw a circle to the left hand side of the page.

Role of inhibitors…If mutations occur to inhibitors – cancer may result i.e. uncontrolled cell cycle.

G1 Phase

S Phase

G2 Phase

Prophase

Metaphase

AnaphaseTelophase

Cell growth

Energy

Organelles

DNA Synthesis

Cell Growth

Energy

CDK complex