THE AUTONOMIC NERVOUS SYSTEM.pptx
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Transcript of THE AUTONOMIC NERVOUS SYSTEM.pptx
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THE AUTONOMICNERVOUS SYSTEM
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Introduction
The autonomic nervous system controls the autonomic
functions of the body i.e. those initiated in the brain below the
level of the cerebrum. Although stimulation does not occur
voluntarily, the individual may be conscious of its effects. For
example, an increase in heart rate.
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Effector organs
The effects of the autonomic activity are rapid and the effector
organs are:
smooth muscle cardiac muscle
glands
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Efferent nerves
The efferent (motor) nerves of the autonomic nervous system
arise from the brain and emerge at various levels between the
midbrain and the sacral region of the spinal cord.
Many travel within the same nerve sheath as peripheral nerves.
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Divisions
The autonomic nervous system has two divisions:
Sympathetic - stressful situations
Parasympathetic - during rest
They work in an opposing manner, thereby maintaining balance
of involuntary functions.
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The sympathetic outflow
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The parasympathetic outflow
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Efferent neurones
Each division of the autonomic nervous system has two efferent
neurones between the central nervous sytem and the effector
organs:
Preganglionic neurone
Postganglionic neurone
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Sympathetic nervous system
The sympathetic nervous system (SNS) is part of the autonomic
nervous system (ANS).The sympathetic nervous system
activates what is often termed the fight or flight response. Like
other parts of the nervous system, the sympathetic nervous
system operates through a series of interconnected neurons.Sympathetic neurons are frequently considered part of the
peripheral nervous system (PNS), although there are many that
lie within the central nervous system (CNS). Sympathetic
neurons of the spinal cord (which is part of the CNS)communicate with peripheral sympathetic neurons via a series
of sympathetic ganglia. Within the ganglia, spinal cord
sympathetic neurons join peripheral sympathetic neurons
through chemical synapses.
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Sympathetic neurons
Spinal cord sympathetic neurons are therefore called presynapticneurons, while peripheral sympathetic neurons are called
postsynaptic (or postganglionic) neurons. At synapses within the
sympathetic ganglia, preganglionic sympathetic neurons release
acetylcholine, a chemical messenger that binds and activates
nicotinic acetylcholine receptors on postganglionic neurons. In
response to this stimulus, postganglionic neurons principally release
noradrenaline (norepinephrine). Prolonged activation can elicit the
release of adrenaline from the adrenal medulla. Once released,
noradrenaline and adrenalinebind adrenergic receptors on peripheral
tissues. Binding to adrenergic receptors
causes the effects seen during the
fight-or-flight response.
These include:
Pupil dilation
Increased sweating
Increased heart rate
Increased blood pressure
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Sympathetic neurones
Two efferent neurones make up the sympathetic nervous system (SNS):
The preganglionic neurone has its cell body in the lateral column of grey
matter in the spinal cord between the levels of the first thoracic and 2nd or 3rd
lumbar vertebrae. The nerve fibre of the cell leaves the cord by the anterior
root and terminates at a synapse in one of the ganglia either in the lateral
chain of sympathetic ganglia or passes through it to one of the paravertebralganglia. Acetylcholine is the neurotransmitter at sympathetic ganglia.
The postganglionic neurone has its cell body in a ganglion and terminates in
the organ or tissue supplied. Noradrenline (norepinephrine) is usually the
neurotransmitter at sympathetic effector organs. The major exception is that
there is no parasympathetic supply to the sweat glands, the skin and bloodvessels of skeletal muscles. These structures are supplied by only
sympathetic postganglionic neurones, which are known as sympathetic
cholinergic nerves and usually have acetylcholine as their neurotransmitter.
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Sympathetic nerves
Sympathetic nerves originate inside the vertebral column, toward themiddle of the spinal cord in the intermediolateral cell column (or
lateral horn), beginning at the first thoracic segment of the spinal cord
and are thought to extend to the second or third lumbar segments.
Because its cells begin in the thoracic and lumbar regions of the
spinal cord, the CNS is said to have a thoracolumbar outflow. Axons
of these nerves leave the spinal cord in the ventral branches (rami) of
the spinal nerves, and then separate out as 'white rami' (so called
from the shiny white sheaths of myelin around each axon) which
connect to two chain ganglia extending alongside the vertebralcolumn on the left and right. These elongated ganglia are also known
as paravertebral ganglia or sympathetic trunks. In these hubs,
connections (synapses) are made which then distribute the nerves to
major organs, glands, and other parts of the body.
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Parasympathetic nervous system
Two neurones are involved in the transmission of impulses from
the source to the effecter organ. The neurotransmitter at both
synapses is aetylcholine:
Preganglionic - long in comparison to its counterpart in the SNS
and has its cell body in the brain or the spinal cord. Those
originating in the brain are the cranial nerves III, VII, IX and X
arising from nuclei in the mid-brain and brain stem, and their
nerve fibres terminate at or near effector organs
Postganglionic - usually very short and has its cell body eitherin a ganglion or in the wall of the organ supplied
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Functions of the autonomic
nervous system
involved in many complex involuntary reflex activities
depends on sensory input to the brain or spinal cord, and or
motor output
reflex action is rapid contraction, or inhibition on contraction ofinvoluntary (smooth and cardiac) muscles or glandular
secretion
activities are coordinated subconsciously in the brain
some sensory input does not reach consciousness - may resultin temporary inhibition of reflex action
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Stimulation
Sympathetic stimulation
allows the body to function under stress
Fight or Flight
Parasympathetic stimulation
controls vegetative functions
feed or breed or rest and response
constant opposition to sympathetic system
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Effects of autonomic stimulation -
sympathetic
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Effects of autonomic stimulation -
parasympathetic
Cardiovascular system
decreases the rate and force of the heart beat
constricts the coronary arteries, reducing the blood supply to the
cardiac muscle
Respiratory system
contraction of the smooth muscle in the airway walls leading to
bronchoconstriction
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Effects of autonomic stimulation -
parasympathetic
Digestive and urinary systems
the liver
the stomach and small intestine
the pancreas urethral and anal sphincters
Eye
contraction of the circular muscle fibres of the iris causes thepupil to constrict
the eyelids tend to close, giving the appearance of sleepiness
the ciliary muscles contract to facilitate near vision.