The Association between Waist Circumference and Renal Insufficiency among Hypertensive Patients
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Transcript of The Association between Waist Circumference and Renal Insufficiency among Hypertensive Patients
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Mrs. Watcharasa Pitug
ID. 567110011-2
The Association between Waist Circumference and Renal Insufficiency
among Hypertensive Patients
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Contents
IntroductionObjectiveMethodsResultsConclusions
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Introduction
Chronic kidney disease (CKD) has become a global public health problem and is a common
condition in the United States(Alejandro et al.,2009 ; Essam et al.,2008 ; Adam
et al., 2007) In 2004, there were approximately 472,000
patients with treated ESRD (Alejandro et al.,2009 )
By 2030, expected to increase to more than 2 million. The estimated prevalence of earlier CKD stages (stages 1 through 4) in US adults was 24
to 28 million based on the 2000 (Adam et al., 2007)
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Chronic kidney disease: classification and clinical consequences
Relative risk of death in relation to kidney function(N=1,120,295 pts) CKD -KDOQI classification
Go AS et., 2004
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Modification of Diet in Renal Disease (MDRD) in Thailand
In 2007 : Chronic Renal Insufficiency patients 13.2% in state 3 and 0.61% in state 4
(Thawee Siriwong, 2007)
In 2008 : Chronic Renal Insufficiency patients in Thailand 17.5% (สมาคมโรคไตแห่�งประเทศไทย, 2008)
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Clinical complications of renal failure
Parathyroid gland
disturbances –renal bone
diseaseActive vitamin D deficiency
Atherosclerosis
and arterioscleros
isPolyneuropathy
No diuresis –overhydration
..and many others
Malnutrition/wasting
Immunodeficiency
Myocardial fibrosis and
cardiomyopathy
Loss of erythropoietin –
anaemia
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Gab of knowledge
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The relationship of obesity to Renal insufficiency is somewhat controversial.
While it is established that obesity increases the risk of hypertension, diabetes and dyslipidemia, it is not clear if excess abdominal waist circumference influences
Renal insufficiency independentlyCorrelation between waist circumference and (A) visceral
and (B) subcutaneous fat areas assessed by using computed tomography in 75 men (open circle; dotted lines) and 47
women (filled triangle; solid lines) with prevalent chronic kidney disease.
Fabiana et al.,2008
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MethodsA analytic study was conducted all information were
collected from medical records of all patients diagnosed with Hypertension during 2012. The type of hypertension complications was based on Renal insufficiency was the main outcome of this study.
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ObjectiveTo investigate the association between abdominal waist
circumference and Renal insufficiency among hypertensive patients
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The inclusion flow chart
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Exclude DM & DMHT(xx,xxx)
Exclude if not estimate waist circumference
(xx,xxx)
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Results
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Basic characteristic of the individual included in the study
N=32,766
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Basic characteristic of the individual included in the study
N=22,167
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Table 2. Crude odds ratios of having Renal Insufficiency and their 95% confidence intervals for each factor
Waist CircumferenceP-value=0.877
(OR=0.99 ; 95%CI=0.85 to 1.14)
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Table. 3. Odds ratios (ORs) of having Renal Insufficiency and their 95% confidence intervals for each factor adjusted for all other factors presented in the table using logistic regression (n=13151)
Waist CircumferenceP-value=0.938 (Adjusted OR=1.01 ; 95%CI=0.82 to
1.24)
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Conclusions
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