The Antwerp Drug Discovery Network - · PDF fileFit for Health and HEALTH-NCP-NET projects are...
Transcript of The Antwerp Drug Discovery Network - · PDF fileFit for Health and HEALTH-NCP-NET projects are...
![Page 1: The Antwerp Drug Discovery Network - · PDF fileFit for Health and HEALTH-NCP-NET projects are funded by the European Commission Strategy ... – 2.3.2 HIV/AIDS, malaria and tuberculosis](https://reader031.fdocuments.us/reader031/viewer/2022030414/5aa08d4c7f8b9a0d158e581b/html5/thumbnails/1.jpg)
Fit for Health and HEALTH-NCP-NET projectsare funded by the European Commission
The Antwerp Drug Discovery Network
University of Antwerp
FP7 Health Partnering event
10 June 2011, Brussels
SME session
![Page 2: The Antwerp Drug Discovery Network - · PDF fileFit for Health and HEALTH-NCP-NET projects are funded by the European Commission Strategy ... – 2.3.2 HIV/AIDS, malaria and tuberculosis](https://reader031.fdocuments.us/reader031/viewer/2022030414/5aa08d4c7f8b9a0d158e581b/html5/thumbnails/2.jpg)
Fit for Health and HEALTH-NCP-NET projectsare funded by the European Commission
Consortium
Academic research platform with:• Industrial standards• Broad international network• Clear and ambitious strategy
WWW.ADDN.BE
![Page 3: The Antwerp Drug Discovery Network - · PDF fileFit for Health and HEALTH-NCP-NET projects are funded by the European Commission Strategy ... – 2.3.2 HIV/AIDS, malaria and tuberculosis](https://reader031.fdocuments.us/reader031/viewer/2022030414/5aa08d4c7f8b9a0d158e581b/html5/thumbnails/3.jpg)
Fit for Health and HEALTH-NCP-NET projectsare funded by the European Commission
Strategy
Academic research platform with:• Industrial standards• Broad international network• Clear and ambitious strategy
Goals• Develop new and promising candidate drugs• Provide in vitro & in vivo compound profiles• Projects in international context• Focus on industrial collaboration
Outcomes• Preclinical candidates• Patents• Preclinical and clinical validation with industry• Spin-offs
![Page 4: The Antwerp Drug Discovery Network - · PDF fileFit for Health and HEALTH-NCP-NET projects are funded by the European Commission Strategy ... – 2.3.2 HIV/AIDS, malaria and tuberculosis](https://reader031.fdocuments.us/reader031/viewer/2022030414/5aa08d4c7f8b9a0d158e581b/html5/thumbnails/4.jpg)
Fit for Health and HEALTH-NCP-NET projectsare funded by the European Commission
Expertise
Academic research platform with:• Industrial standards• Broad international network• Clear and ambitious strategy
• High capacity evaluation of anti-infective agents
• ‘Hit-to-lead’ and ‘lead optimization’ medicinal chemistry projects
• In silico and in vitro physicochemical characterization
• In vivo pharmacokinetic studies
• Design, synthesis and evaluation of chemical probes– Target identification & validation– Compound validation– Biomarker & bio-imaging research
![Page 5: The Antwerp Drug Discovery Network - · PDF fileFit for Health and HEALTH-NCP-NET projects are funded by the European Commission Strategy ... – 2.3.2 HIV/AIDS, malaria and tuberculosis](https://reader031.fdocuments.us/reader031/viewer/2022030414/5aa08d4c7f8b9a0d158e581b/html5/thumbnails/5.jpg)
Fit for Health and HEALTH-NCP-NET projectsare funded by the European Commission
EU Collaborations
Academic research platform with:• Industrial standards• Broad international network• Clear and ambitious strategy
![Page 6: The Antwerp Drug Discovery Network - · PDF fileFit for Health and HEALTH-NCP-NET projects are funded by the European Commission Strategy ... – 2.3.2 HIV/AIDS, malaria and tuberculosis](https://reader031.fdocuments.us/reader031/viewer/2022030414/5aa08d4c7f8b9a0d158e581b/html5/thumbnails/6.jpg)
Fit for Health and HEALTH-NCP-NET projectsare funded by the European Commission
• Topic interest 2012– 1.2 Detection diagnosis and monitoring
– 2.1.2 Systems biology– 2.2.2 Human development and aging
– 2.3.2 HIV/AIDS, malaria and tuberculosis
• ADDN input– Medicinal chemistry
– In vitro and in vivo evaluation for infectious diseases– PK studies
– Biochemical evaluation/molecular biology
– Activity-based probes
Topic
![Page 7: The Antwerp Drug Discovery Network - · PDF fileFit for Health and HEALTH-NCP-NET projects are funded by the European Commission Strategy ... – 2.3.2 HIV/AIDS, malaria and tuberculosis](https://reader031.fdocuments.us/reader031/viewer/2022030414/5aa08d4c7f8b9a0d158e581b/html5/thumbnails/7.jpg)
Fit for Health and HEALTH-NCP-NET projectsare funded by the European Commission
Thank you!
Jurgen Joossens, PhD, Pharm. D. Research & Innovation Manager Drug Discovery Medicinal Chemistry University of AntwerpCampus Drie Eiken, Office A2.05Universiteitsplein 1BE-2610 Wilrijk , BelgiumTel. +32 (0)3.265.28.92http://www.addn.be
Contact details