The Antwerp Drug Discovery Network - · PDF fileFit for Health and HEALTH-NCP-NET projects are...

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Fit for Health and HEALTH-NCP-NET projects are funded by the European Commission The Antwerp Drug Discovery Network University of Antwerp FP7 Health Partnering event 10 June 2011, Brussels SME session

Transcript of The Antwerp Drug Discovery Network - · PDF fileFit for Health and HEALTH-NCP-NET projects are...

Page 1: The Antwerp Drug Discovery Network - · PDF fileFit for Health and HEALTH-NCP-NET projects are funded by the European Commission Strategy ... – 2.3.2 HIV/AIDS, malaria and tuberculosis

Fit for Health and HEALTH-NCP-NET projectsare funded by the European Commission

The Antwerp Drug Discovery Network

University of Antwerp

FP7 Health Partnering event

10 June 2011, Brussels

SME session

Page 2: The Antwerp Drug Discovery Network - · PDF fileFit for Health and HEALTH-NCP-NET projects are funded by the European Commission Strategy ... – 2.3.2 HIV/AIDS, malaria and tuberculosis

Fit for Health and HEALTH-NCP-NET projectsare funded by the European Commission

Consortium

Academic research platform with:• Industrial standards• Broad international network• Clear and ambitious strategy

WWW.ADDN.BE

Page 3: The Antwerp Drug Discovery Network - · PDF fileFit for Health and HEALTH-NCP-NET projects are funded by the European Commission Strategy ... – 2.3.2 HIV/AIDS, malaria and tuberculosis

Fit for Health and HEALTH-NCP-NET projectsare funded by the European Commission

Strategy

Academic research platform with:• Industrial standards• Broad international network• Clear and ambitious strategy

Goals• Develop new and promising candidate drugs• Provide in vitro & in vivo compound profiles• Projects in international context• Focus on industrial collaboration

Outcomes• Preclinical candidates• Patents• Preclinical and clinical validation with industry• Spin-offs

Page 4: The Antwerp Drug Discovery Network - · PDF fileFit for Health and HEALTH-NCP-NET projects are funded by the European Commission Strategy ... – 2.3.2 HIV/AIDS, malaria and tuberculosis

Fit for Health and HEALTH-NCP-NET projectsare funded by the European Commission

Expertise

Academic research platform with:• Industrial standards• Broad international network• Clear and ambitious strategy

• High capacity evaluation of anti-infective agents

• ‘Hit-to-lead’ and ‘lead optimization’ medicinal chemistry projects

• In silico and in vitro physicochemical characterization

• In vivo pharmacokinetic studies

• Design, synthesis and evaluation of chemical probes– Target identification & validation– Compound validation– Biomarker & bio-imaging research

Page 5: The Antwerp Drug Discovery Network - · PDF fileFit for Health and HEALTH-NCP-NET projects are funded by the European Commission Strategy ... – 2.3.2 HIV/AIDS, malaria and tuberculosis

Fit for Health and HEALTH-NCP-NET projectsare funded by the European Commission

EU Collaborations

Academic research platform with:• Industrial standards• Broad international network• Clear and ambitious strategy

Page 6: The Antwerp Drug Discovery Network - · PDF fileFit for Health and HEALTH-NCP-NET projects are funded by the European Commission Strategy ... – 2.3.2 HIV/AIDS, malaria and tuberculosis

Fit for Health and HEALTH-NCP-NET projectsare funded by the European Commission

• Topic interest 2012– 1.2 Detection diagnosis and monitoring

– 2.1.2 Systems biology– 2.2.2 Human development and aging

– 2.3.2 HIV/AIDS, malaria and tuberculosis

• ADDN input– Medicinal chemistry

– In vitro and in vivo evaluation for infectious diseases– PK studies

– Biochemical evaluation/molecular biology

– Activity-based probes

Topic

Page 7: The Antwerp Drug Discovery Network - · PDF fileFit for Health and HEALTH-NCP-NET projects are funded by the European Commission Strategy ... – 2.3.2 HIV/AIDS, malaria and tuberculosis

Fit for Health and HEALTH-NCP-NET projectsare funded by the European Commission

Thank you!

[email protected]

Jurgen Joossens, PhD, Pharm. D. Research & Innovation Manager Drug Discovery Medicinal Chemistry University of AntwerpCampus Drie Eiken, Office A2.05Universiteitsplein 1BE-2610 Wilrijk , BelgiumTel. +32 (0)3.265.28.92http://www.addn.be

Contact details