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The 1 st World Congress on Controversies in Cryopreservation of Stem Cells, Reproductive Cells, Tissue & Organs (CRYO) The Academy for Clinical Debates & Controversies in Medicine www.comtecmed.com/cryo A comprehensive Congress fully devoted to clinical debates and controversial issues in the field of Cryopreservation of Stem cells, Reproductive cells, Tissue and Organs. VALENCIA SPAIN APRIL 22-25, 2010 &

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The 1st World Congress on Controversies inCryopreservation of Stem Cells,

Reproductive Cells, Tissue & Organs (CRYO)

The Academy for Clinical Debates & Controversies in Medicine

www.comtecmed.com/cryo

A comprehensive Congress fully devoted to clinical debates and controversial issues in the fieldof Cryopreservation of Stem cells, Reproductive cells, Tissue and Organs.

VALENCIA • SPAIN • APRIL 22-25, 2010

&

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In recent years the field of Cryopreservation has witnessed enormous expansionin clinical and basic data. Conferences are becoming more and more informativebut there is often only limited time for thorough discussion. There seems to bea gap between the enormous expansion of knowledge in the field ofcryopreservation and the dissemination of that knowledge. This developmenthas created a great need to debate the many controversial issues and crystallizethem into clinical conclusions.

This controversies Congress stems from the fact that current congresses fail topromote true clinical discussion between practicing physicians and researcherson unresolved pressing issues.

Allowing ample time for speaker-audience discussion, the congress aims atreaching up-to-date and agreed-upon answers to ongoing debates even whenproof is lacking, through evidence-based medicine and expert opinion.

The purpose of the Cryopreservation of Stem cells, Reproductive Cells, Tissue andOrgans Congress is to disseminate information in our field by debating the multiplecontroversial issues and reaching consensus when possible.

We invite you to take part in The First International Congress on Controversiesin Cryopreservation of Stem cells, Reproductive cells, Tissue and Organs (CRYO)which will be a milestone for future congresses.

We look forward to an exciting scientific event in the beautiful city of Valencia.

A. Arav A. Nagler A. Pellicer Z. Shoham S. Slavin G. StaceyCongress Chairmen

Dear Friends and Colleagues,

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The 1st World Congress on Controversies in Cryopreservation of Stem Cells, Reproductive Cells, Tissue & Organs (CRYO)

Valencia • Spain • April 22-25, 2010

A. Arav, IsraelA. Nagler, IsraelA. Pellicer, SpainZ. Shoham, IsraelS. Slavin, IsraelG. Stacey, UK

CONGRESS CHAIRMEN

SCIENTIFIC COMMITTEESTEM CELLS: IVF: SPERM, OOCYTES, FERTILITY ANIMAL MODEL:EMBRYONIC AND ZYGOTES, EMBRYOS PRESERVATION: SPERM, OOCYTES,ADULT STEM CELLS AND BLASTOCYSTS OVARIAN CORTEX, EMBRYOS AND SOMATIC• A. Arav, Israel • S. Leibo, USA WHOLE OVARY CELLS FOR NT• F. Gandolfi, Italy • J. Liebermann, USA • R. Casper, Canada • T. Hildebrandt, Germany• A. Nagler, Israel • P. Nagy, USA • J. Donnez, Belgium • P. Loi, Italy• C. Simon, Spain • A. Pellicer, Spain • T. Falcone, USA • G. Seidel, USA• S. Slavin, Israel • Z. Shoham, Israel • R. Gosden, USA

• G. Vajta, Australia • P. Patrizio, USA

LOCAL SCIENTIFIC COMMITTEEJ. AlemanyP. BarriJ. CallejoJ. Casas Fernandez de TejerinaA. CoboM. J. de los Santos

J. DomingoJ. A. Garcia-VelascoM. MeseguerJ. RemohiG. SanzC. Simon

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HANDS-ON WORKSHOP:OOCYTE AND EMBRYO VITRIFICATION

Afternoon sessions

THE CRYOTOP METHODThe "hands-on" laboratory program, general principles ofcryobiology, minimum volume methods, cooling rates and differentvitrification devices will be discussed in a scheduled program oftalks and demos performed by recognized scientists top in thefield of cryobiology

Workshop 1Valencia

Moderator:A. Cobo, Spain

Supported by an unrestrictededucational grant from Ferring

Morning session of workshops 1, 2, 3, 4THEORETICAL SESSIONSupported by an unrestricted educational grant from FerringFundamentals of cryobiology | S. Leibo, USAVitrification of oocytes and embryos | A. Arav, IsraelDifferent approaches of vitrification | G. Vajta, AustraliaThe cryotop method for oocyte vitrification. Description of the technique. Clinical results | M. Kuwayama, Japan

Workshop 2Alicante

Moderator:M. Kuwayama, Japan

Workshop 4Valencia

Discussions on how to managea Cryo-bank and the problemsarising from this

Management of an egg bank: theIVI experienceM. Jos de los Santos, Spain

Ethical and counselling issuesarising from 'social' egg freezingG. Lockwood, UK

Practical approaches to in themanagement of a cryo donoroocyte bankP. Nagy, USA

Workshop 3Valencia

Moderators:A. Arav, Israel, Y. Barak, Israel

VITRIFCATION IN A CLOSEDSYSTEMClosed system vitrificationtechniques will be demonstrated.Participants will try to vitrifyoocytes using Sealed SOPS and theVitMaster. Problems duringvitrification will be reviewed andmethods required to solve themrevealed

THURSDAY, APRIL 22, 2010

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The 1st World Congress on Controversies in Cryopreservation of Stem Cells, Reproductive Cells, Tissue & Organs (CRYO)

Valencia • Spain • April 22-25, 2010

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The 1st World Congress on Controversies in Cryopreservation of Stem Cells, Reproductive Cells, Tissue & Organs (CRYO)

Valencia • Spain • April 22-25, 2010

PRELIMINARY PROGRAM

Plenary Session 108:30-10:30 BASIC UNDERSTANDING OF VITRIFICATION

– PART 1Supported by an unrestricted educational grant from MerckSeronoPanel: A. Arav, Israel, M. Meseguer, Spain

08:30-09:00 Biosafety of vitrification – the issue of contamination using an open system| G. Vajta, Australia

09:00-09:30 Rationale of cryopreservation by very high cooling and warming rates| S. Leibo, USA

09:30-10:00 Basic principles of vitrification| A. Arav, Israel

10:00-10:30 Vitrification of bovine and equine embryos- practical considerations| G. Seidel, USA

10:30-11:00 Coffee Break

11:00-13:00 BASIC UNDERSTANDING OF VITRIFICATION– PART 2

Supported by an unrestricted educational grant from MerckSerono

Panel: M. Jos de los Santos, Spain,M. Kuwayama, Japan, G. Seidel, USA,G. Vajta, Australia

11:00-12:00 Debate: Cryopreservation of oocytes –slow freezing vs. vitrificationSlow freezing: G. Coticchio, ItalyVitrification: P. Nagy, USA

12:00-13:00 Debate: Clinical application – what arethe limits?A. Cobo, Spain, L. Rienzi, Italy

13:00-14:00 Lunch break

Session 214:00-15:30 WHAT CAN GO WRONG IN

CRYOPRESERVATION?Chairpersons: J. Remoh , Spain

14:00-14:30 Errors that can occur when applying cryopreservation technology in the real world,and how to minimize these errors| J. Hasler, USA

14:30-15:00 What can go wrong during vitrification?| S. Ledda, Italy

15:00-15:30 Cellular damage during cryopreservation| J. Van Blerkom, USA

FRIDAY, APRIL 23, 2010

Session 314:00-15:30 SPERM FREEZING IN PRIMATESChairpersons: W. Ji, China

14:00-14:30 Cryopreservation of spermatozoon in rhesus and cynomogus monkey| W. Ji, China

14:30-15:00 Intracellular ice formation in spermatozoa?| G.J. Morris, UK

15:00-15:30 Freeze dried sperm| T. Wakayama, Japan

15:30-16:00 Coffee break

Session 416:00-18:00 FREEZING OF EMBRYONIC & ADULT STEM

CELLS – VARIOUS TECHNIQUESChairpersons: O. Hovatta, Sweden

16:00-16:30 Cryopreservation of human embryonic stem cells| O. Hovatta, Sweden

16:30-17:00 Large animals models in regenerative medicine:the need and the limits| F. Gandolfi, Italy

17:00-17:30 Tumorigenicity of pluripotent stem cells| N. Benvenisty, Israel

17:30-18:00 Cryopreservationof adult stem cells| R. Devireddy, USA

Session 516:00-18:00 CORD BLOOD BANKING, BIOLOGY,

TRANSPLANTATION AND TISSUE REGENERATION

Chairpersons: W. Arcese, Italy, A. Nagler, Israel

16:00-16:20 Cord Blood Banking – public vs. private network| S. Querol, Spain

16:20-16:40 Cord Blood cryobiology: liquid nitrogen, cryoprotectant vs. lyophilization| P. Rebulla, Italy

16:40-17:00 Cord Blood Transplantation: Do we know the best option for alternative donor transplant:MUD vs. CB vs. Haplo?| W. Arcese, Italy

17:00-17:20 Cord Blood Transplantations: Strategies to facilitate engraftment, do we know the best one?| M. Fernandez, Spain

17:20-17:40 Cord Blood Tissue Regeneration Potential: Mesenchymal stem cells (MSCs) heart, vascular,neurology. Does it exist at all?| A. Nagler, Israel

17:40-18:00 Discussion

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The 1st World Congress on Controversies in Cryopreservation of Stem Cells, Reproductive Cells, Tissue & Organs (CRYO)

Valencia • Spain • April 22-25, 2010

PRELIMINARY PROGRAM

Plenary Session 608:30-10:30 STEM CELL – PRESERVATION OF FUTURE

MEDICINE – PART 1Supported by an unrestricted educational grant from IBSA/AngeliniChairpersons: C. Simon, Spain, S. Slavin, Israel

08:30-09:00 Adult stem cells vs. embryonic stem cells| C. Simon, Spain

09:00-09:30 Somatic cells into stem cells. Reprogramming!| A. Raya, Spain

09:30-10:00 Preclinical and clinical trials of stem cells therapy| O. Hovatta, Sweden

10:00-10:30 Pluripotent stem cells in medical research| N. Benvenisty, Israel

10:30-11:00 Coffee break

11:00-13:00 STEM CELL – PRESERVATION OF FUTURE MEDICINE – PART 2

Supported by an unrestricted educational grant from IBSA/AngeliniChairpersons:

11:00-11:30 The ethics of manufacturing gametes in the lab| G. Pennings, Belgium

11:30-12:00 The use of cord blood stem cells for tissue therapeutics| R. Casper, Canada

12:00-12:30 Future use of stem cells in medicine| S. Slavin, Israel

12:30-13:00 Future medicine of pluripotent cells| TBA

13:00-14:00 Lunch break

Session 714:00-15:30 ANIMAL EMBRYO FREEZINGChairpersons: T. Hildebrandt, Germany

14:00-14:30 Domestic animal embryo freezing| D. Rath, Germany

14:30-15:00 Freeze dried cells for nuclear transfer| P. Loi, Italy

15:00-15:30 Animal cloning from frozen dead body| T. Wakayama, Japan

SATURDAY, APRIL 24, 2010

Session 814:00-15:30 FERTILITY, TISSUE AND ORGAN

PRESERVATIONChairpersons: J. Garc a Velasco, Spain, P. Patrizio, USA,

Z. Shoham, Israel

14:00-14:30 What to freeze: Whole ovary, cortex or other?| P. Patrizio, USA

14:30-15:00 Duration of function of fresh and frozen ovarytransplants| S. Silber, USA

15:00-15:30 Where to transplant: Heterotopic or orthotopicsites?| J. Donnez, Belgium

15:30-16:00 Coffee break

Session 916:00-18:00 EMBRYO FREEZINGChairpersons: J. Domingo, Spain, J. Liebermann, USA,

P. Nagy, USA

16:00-16:30 What is the best stage for freezing? From 2PNto blastocyst| J. Liebermann, USA

16:30-17:00 Neonatal outcome from vitrified cleavage stageto embryos| G.A. Rama Raju, India

17:00-17:30 Vitrification of blastocysts: It is the way to go!| P. Vanderzwalmen, Belgium

17:30-18:00 Embryo freezing: A key to elective single embryo transfer (eSET)| P. Barri, Spain

Session 1016:00-18:00 COMPANY PRESENTATIONS16:00-16:15 Core Dynamics – Freeze dry of stem cells

| D. Nathan, Israel

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CONTINUED

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The 1st World Congress on Controversies in Cryopreservation of Stem Cells, Reproductive Cells, Tissue & Organs (CRYO)

Valencia • Spain • April 22-25, 2010

PRELIMINARY PROGRAM

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Plenary Session 1108:30-10:00 CRYO-BANKChairpersons: J. Callejo, Spain, G. Stacey, UK

08:30-09:00 Medical and social aspects of cryopreservationof oocytes for fertility preservation| G. Lockwood, UK

09:00-09:30 Legislation of cryopreservation of gametes, tissue and regulation of transportation between countries| C. O’Toole, UK

09:30-10:00 The use of cryopreservation of tumor tissue for preparation of tumor cell vaccines and forfuture evaluation of molecular pathways| S. Slavin, Israel

10:00-10:30 Coffee break

SUNDAY, APRIL 25, 2010

Plenary Session 1210:30-12:00 IS IT POSSIBLE TO RESTORE SPERM FROM

CRYOPRESERVED TISSUE OR SHOULD WE ALWAYS GET A FRESH ONE?

Chairpersons: A. Pellicer, Spain, Z. Shoham, Israel

10:30-11:00 Advantages of using cryopreserved TESE against freshly obtained tissue| M. Gil-Salom, Spain

11:00-11:30 Multipotent adult germ line stem cells: New therapeutic hope?| K. Guan, Germany

11:30-12:00 Clinical evaluation of the harmful effects of sperm freezing and its current indications| N. Garrido, Spain

12:00 Closing

CONTINUED

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MAJOR SPONSORSHIP OPPORTUNITIES

SATELLITE SYMPOSIUM(NON-CME APPROVED) 40,000

The Sponsor may organize an industrial non-CME Satellite Symposium (1.5 - 2 hours) as part ofthe Scientific Program. Organizing Committee approval of the content and speakers is required.The date and time of the Symposium will be mutually agreed upon.The expenses of the Symposium’s chairpersons and speakers (registration, accommodation andtravel) will be the responsibility of the Sponsor.

Provided by the Congress• Symposium hall and standard audiovisual equipment• Five complimentary registrations (for Symposium chairpersons and speakers)• A 100-word sponsor/product profile will be published in the final Congress Program• Approximately 15 sq.m exhibition space

(Additional space may be purchased at the reduced price of 400 Euro per sq.m)• Two complimentary registrations for exhibitors

(Additional exhibitors’ registrations may be purchased at 350 Euro per person)• One A4 page advertisement, full color, will be published in the final Congress Program• The Sponsor’s logo will be published on the Congress Website, providing a two-way link• The Sponsor will be acknowledged in the final Congress Program, and the Sponsor’s logo will appear on a

separate Sponsor Logo page• The Sponsor’s logo will appear on a Sponsor Board on site• The Sponsor's brochure will be inserted in the participants’ bags

CONTINUING MEDICAL EDUCATION (CME)APPROVED SYMPOSIUM 30,000

The Sponsor may donate an unrestricted grant to support an existing session or suggest a CME-approved session (1.5 - 2 hours) as part of the Scientific Program.The expenses of the Symposium’s chairpersons and speakers (registration, accommodation andtravel) will be the responsibility of the Sponsor.

Provided by the Congress• Symposium hall and standard audiovisual equipment• Four complimentary registrations (for Symposium chairpersons and speakers)• A 100-word sponsor/product profile will be published in the final Congress Program• Exhibition space of 10 sq.m

(Additional space may be purchased at the reduced price of 400 Euro per sq.m)• Two complimentary registrations for exhibitors

(Additional exhibitors’ registrations may be purchased at 350 Euro per person)• One A4 page advertisement, full color, will be included in the final Congress Program• The Sponsor’s logo will be published on the Congress Website, providing a two-way link• The Sponsor will be acknowledged in the final Congress Program, and the Sponsor’s logo will appear on a

separate Sponsor Logo page• The Sponsor’s logo will appear on a Sponsor Board on site• The Sponsor's brochure will be inserted in the participants' bags

The 1st World Congress on Controversies in Cryopreservation of Stem Cells, Reproductive Cells, Tissue & Organs (CRYO)

Valencia • Spain • April 22-25, 2010

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25,000LUNCH per lunch

The Sponsor may subsidize in part a buffet lunch served on Friday, (April 23) and/or on Saturday(April 24).

Provided by the Congress• Four complimentary registrations (for the Sponsor’s staff)• The Sponsor’s logo will appear on a special board at the lunch venue• A 100-word sponsor/product profile will be published in the final Congress Program• One A4 half-page advertisement, full color, will be published in the final Congress Program• The Sponsor’s logo will be published on the Congress Website, providing a two-way link• The Sponsor will be acknowledged in the final Congress Program, and the Sponsor’s logo will appear on a

separate Sponsor Logo page• The Sponsor’s logo will appear on a Sponsor Board on site• The Sponsor’s brochure will be inserted in the participants' bags

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MAJOR SPONSORSHIP OPPORTUNITIESCONTINUED

PRE/POST-CONGRESS SATELLITE SYMPOSIUM(NON-CME APPROVED) 50,000

(This option is particularly suited for drug launching and other special events)The Sponsor may organize an industrial non-CME approved Pre/Post-Congress Satellite Symposium,for 3-4 hours (or more) on Thursday (April 22), before the official opening of the Congress, or atthe end (April 25) of the Congress.The expenses of the Symposium’s chairpersons and speakers (registration, accommodation andtravel) will be the responsibility of the Sponsor.

Provided by the Congress• Symposium hall and standard audiovisual equipment• Six complimentary registrations (for Symposium chairpersons and speakers)• A 100-word sponsor/product profile will be published in the final Congress Program• Approximately 20 sq.m exhibition space

(Additional space may be purchased at the reduced price of 400 Euro per sq.m)• Two complimentary registrations for exhibitors

(Additional exhibitors’ registration may be purchased at 350 Euro per person)• One A4 page advertisement, full color, will be published in the final Congress Program• The Sponsor’s logo will be published on the Congress Website, providing a two-way link• The Sponsor will be acknowledged in the final Congress Program, and the Sponsor’s logo will appear on a

separate Sponsor Logo page• The Sponsor’s logo will appear on a Sponsor Board on site• The Sponsor's brochure will be inserted in the participants’ bags

The 1st World Congress on Controversies in Cryopreservation of Stem Cells, Reproductive Cells, Tissue & Organs (CRYO)

Valencia • Spain • April 22-25, 2010

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In addition to the major sponsorship opportunities, a range of other sponsorshippackages is available to meet various needs.

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SPONSORSHIP OPPORTUNITIES

10,000E-POSTERS: Sole Sponsorship

An E-Poster is an electronic version of the traditional poster board. The posters will be displayedon monitor screens and will include text, figures as well as videos.Abstracts will be displayed as an electronic poster (e-poster) during the days of the Congress. Theelectronic version of the posters will be uploaded to a virtual conference library (VCL), where theycan be viewed during and after the Congress for a period of time.

Provided by the Congress the opportunity to• Display Sponsor logo/information on screensaver• Display Sponsor logo/information on screen background• Distribute mouse pads and related promotional gifts

Provided by the Congress• The Sponsor’s logo will be published on the Congress Website, providing a two-way link• The Sponsor will be acknowledged in the final Congress Program and the logo will appear on a separate Sponsor

Logo page• The Sponsor’s logo will appear on a Sponsor Board on site

15,000CONGRESS PROGRAM: Sole Sponsorship

The final Congress Program will include the Scientific Program and the Scientific Abstracts of theCongress. The Congress Program will be distributed to all participants and will be an invaluablereference book after the Congress.

Provided by the Congress• One A4 page advertisement, full color, will be published on the back cover of the final Congress Program• A 100-word sponsor/product profile will be published in the final Congress Program• The Sponsor’s logo will be published on the Congress Website providing a two-way link• The Sponsor will be acknowledged in the final Congress Program, and the Sponsor’s logo will appear on a

separate Sponsor Logo page• The Sponsor’s logo will appear on a Sponsor Board on site

15,000WELCOME RECEPTION: Sole Sponsorship

A Welcome Reception for all participants will be held on Thursday evening (April 22) at theCongress venue.

Provided by the Congress• The Sponsor’s logo will appear on a special board at the Welcome Reception venue• A 100-word sponsor/product profile will be published in the final Congress Program• One A4 half-page advertisement, full color, will be published in the final Congress Program• The Sponsor’s logo will be published on the Congress Website, providing a two-way link• The Sponsor will be acknowledged in the final Congress Program, and the Sponsor’s logo will appear on a

separate Sponsor Logo page• The Sponsor’s logo will appear on a Sponsor Board on site• The Sponsor’s brochure will be inserted in the participants' bags

The 1st World Congress on Controversies in Cryopreservation of Stem Cells, Reproductive Cells, Tissue & Organs (CRYO)

Valencia • Spain • April 22-25, 2010

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SPONSORSHIP OPPORTUNITIESCONTINUED

10,000FACULTY DINNER: Sole Sponsorship

A Faculty Dinner will be held for the invited speakers of the Congress.

Provided by the Congress• The Sponsor’s logo will appear on a special board at the Faculty Dinner venue• The Sponsor’s logo will be published on the Congress Website, providing a two-way link• The Sponsor will be acknowledged in the final Congress Program, and the Sponsor’s logo will appear on a

separate Sponsor Logo page• The Sponsor’s logo will appear on a Sponsor Board on site

10,000INTERNET CENTER: Sole Sponsorship

The Internet Center will be outfitted with Internet workstations for participants of the Congressto check their email and stay updated in-between sessions. The sponsorship package entails tohave provided: workstations, areas for corporate logo display, technical support, furniture, adequatespace for the workstations and Internet set-up and connection.

Provided by the Congress the opportunity to:• Display Sponsor logo/information on screensaver• Display Sponsor logo/information on screen background• Distribute mouse pads and related promotional gifts at the internet center

Provided by the Congress:• The Sponsor’s logo will be published on the Congress Website, providing a two-way link• The Sponsor will be acknowledged in the final Congress Program and the logo will appear on a separate Sponsor

Logo page• The Sponsor’s logo will appear on a Sponsor Board on site

The 1st World Congress on Controversies in Cryopreservation of Stem Cells, Reproductive Cells, Tissue & Organs (CRYO)

Valencia • Spain • April 22-25, 2010

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SPONSORSHIP OPPORTUNITIESCONTINUED

CONGRESS WEBSITE: Sole Sponsorship

The Congress Website is www.comtecmed.com/cryo.Participants can register for the Congressas well as book their accommodation on-line. Submission of abstracts will only be possible via theCongress Website, and all abstracts will be available on the Website, both during and after theCongress. The Website will be maintained for the year following the Congress.

Provided by the Congress• The Sponsor’s logo will be published on the Congress Website, providing a two-way link• The Sponsor will be acknowledged in the final Congress Program, and the Sponsor’s logo will appear on a

separate Sponsor Logo page• The Sponsor’s logo will appear on a Sponsor Board on site

8,000

The 1st World Congress on Controversies in Cryopreservation of Stem Cells, Reproductive Cells, Tissue & Organs (CRYO)

Valencia • Spain • April 22-25, 2010

10,000PARTICIPANTS’ BAGS: Sole Sponsorship

The Sponsor will provide the participants’ Congress bags.

Provided by the Congress:• The Sponsor's brochure/s will be inserted in the participants' bags• The Sponsor’s logo will be published on the Congress Website, providing a two-way link• The Sponsor will be acknowledged in the final Congress Program, and the Sponsor’s logo will appear on a

separate Sponsor Logo page• The Sponsor’s logo will appear on a Special Board on site

provided-in-kind +

10,000CD-ROM: Sole Sponsorship

The CD-Rom will contain all of the Scientific Abstracts of the Congress and will be distributed toall the participants. The CD-Rom may include the Sponsor’s logo.An exchange voucher (printed by the Sponsor) will be placed in the participants’ bags.

Provided by the Congress:• Exclusive advertisement on the cover of the voucher• Exclusive advertisement on the cover of the CD-ROM cover

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VIDEO WEBCAST

The Congress will provide a Video Webcast of your session/symposium, (up to 2 hours) which canbe placed on the official COPHy Web site at www.comtecmed.com/cophy (pending the speakers'approval).A Video Webcast is a media file distributed over the Internet using streaming media technology.The Video webcast will be greatly beneficial for your company, both for your visibility and foryour targets. The Video Webcast represents outstanding material for distribution through yourrepresentatives of your affiliates in the different countries.

Provided by the Congress• The Sponsor's edited webcast with the sponsors logo will be published on the Congress Website, providing a

two-way link (if necessary)• The Sponsor will be acknowledged in the final Congress Program, and the Sponsor’s logo will appear on a

separate Sponsor Logo page• The Sponsor’s logo will appear on a Sponsor Board on site• The Congress will provide a CD

5,000

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SPONSORSHIP OPPORTUNITIES

The 1st World Congress on Controversies in Cryopreservation of Stem Cells, Reproductive Cells, Tissue & Organs (CRYO)

Valencia • Spain • April 22-25, 2010

AUDIO WEBCAST

The Congress will provide an Audio Webcast of your session/symposium, (up to 2 hours) whichcan be placed on the official COPHy Web site at www.comtecmed.com/cophy (pending the speakers'approval).A Audio Webcast is a media file distributed over the Internet using streaming media technology.The Audio webcast will be greatly beneficial for your company, both for your visibility and foryour targets. The Audio Webcast represents outstanding material for distribution through yourrepresentatives of your affiliates in the different countries.

Provided by the Congress• The Sponsor's edited webcast with the sponsors logo will be published on the Congress Website, providing a

two-way link (if necessary)• The Sponsor will be acknowledged in the final Congress Program, and the Sponsor’s logo will appear on a

separate Sponsor Logo page• The Sponsor’s logo will appear on a Sponsor Board on site

2,500

CONTINUED

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MINI/POCKET PROGRAM: Sole Sponsorship

A Mini/Pocket Program will be distributed to all participants with their registration kits.Provided by the Congress

• The Sponsor’s exclusive advertisement on the back cover of the Mini/Pocket Program• The Sponsor’s logo will be published on the Congress Website, providing a two-way link• The Sponsor will be acknowledged in the final Congress Program, and the Sponsor’s logo will appear on a

separate Sponsor Logo page• The Sponsor’s logo will appear on a Sponsor Board on site

5,000

TRANSLATION

Simultaneous translation from English to any required language.Provided by the Congress

• The Sponsor’s logo will appear on a special board in the session hall• The Sponsor’s logo will be published on the Congress Website, providing a two-way link• The Sponsor will be acknowledged in the final Congress Program, and the Sponsor’s logo will appear on a

separate Sponsor Logo page• The Sponsor’s logo will appear on a Sponsor Board on site

5,000per hall per day

WRITING PADS AND PENS: Sole Sponsorship

The Sponsor will provide all participants with writing pads and pens, which will be included inthe participants’ bags.This can be an effective high-profile sponsorship opportunity for a drug launch or for immediatebrand recognition.Provided by the Congress

• The Sponsor’s logo will be published on the Congress Website, providing a two-way link• The writing pads and pens will bear the Sponsor’s company product/logo

5,000provided-in-kind +

� 14 �

SPONSORSHIP OPPORTUNITIESCONTINUED

CONGRESS LANYARDS: Sole SponsorshipThe Sponsor provides printed lanyards for the name badgesThe Congress provides printed lanyards for the name badges

3,0006,000

Provided by the Congress• The Sponsor/product name, logo or text printed on lanyards• The Sponsor’s logo will be published on the Congress Website, providing a two-way link• The Sponsor will be acknowledged in the final Congress Program, and the Sponsor’s logo will appear on a

separate Sponsor Logo page• The Sponsor’s logo will appear on a Special Board on site

The 1st World Congress on Controversies in Cryopreservation of Stem Cells, Reproductive Cells, Tissue & Organs (CRYO)

Valencia • Spain • April 22-25, 2010

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EUROPEAN SPEAKER

The Sponsor may support in part the expenses of one or more invited European Speaker.Expenses include registration, accommodation and travel.Provided by the Congress

• The Sponsor’s logo will be published on the Congress Website, providing a two-way link• A half-page advertisement, full color, will be published in the final Congress Program• The Sponsor will be acknowledged in the final Congress Program, and the Sponsor’s logo will appear on a

separate Sponsor Logo page• The Sponsor’s logo will appear on a Sponsor Board on site

3,000

� 15 �

SPONSORSHIP OPPORTUNITIESCONTINUED

The 1st World Congress on Controversies in Cryopreservation of Stem Cells, Reproductive Cells, Tissue & Organs (CRYO)

Valencia • Spain • April 22-25, 2010

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PRIZES FOR OUTSTANDING ABSTRACTS: Sole Sponsorship

Six prizes of 500 Euro each will be awarded to the authors of the six most outstanding abstracts/posters.The winners will be announced at the Congress and will appear on the Website after the Congress.The Sponsor’s representatives will be invited to attend the prize-giving.

Provided by the Congress• The Sponsor’s logo will be published on the Congress Website, providing a two-way link• The Sponsor will be acknowledged in the final Congress Program, and the Sponsor’s logo will appear on a

separate Sponsor Logo page• The Sponsor’s logo will appear on a Sponsor Board on site

3,000

BROCHURE INSERT

A brochure provided by the Sponsor will be inserted in the participants’ bags, which will bedistributed to all of the participants of the Congress.

Provided by the Congress• The Sponsor’s logo will be published on the Congress Website, providing a two-way link

3,000

COFFEE BREAK

Coffee will be served during the breaks between the sessions on each day of the Congress.

Provided by the Congress• The Sponsor’s logo will be published on the Congress Website, providing a two-way link• The Sponsor will be acknowledged in the final Congress Program, and the Sponsor’s logo will appear on a

separate Sponsor Logo page• The Sponsor’s logo will appear on a Sponsor Board on site

2,000

per coffee break

� 16 �

SPONSORSHIP OPPORTUNITIESCONTINUED

NON-EUROPEAN SPEAKER

The Sponsor may support in part the expenses of one or more invited Non-European Speaker.Expenses include registration, accommodation and travel.

Provided by the Congress• The Sponsor’s logo will be published on the Congress Website, providing a two-way link• An A4 half-page advertisement, full color, will be published in the final Congress Program• The Sponsor’s brochure will be inserted in the participants' bags• The Sponsor will be acknowledged in the final Congress Program, and the Sponsor’s logo will appear on a

separate Sponsor Logo page• The Sponsor’s logo will appear on a Sponsor Board on site

6,000

The 1st World Congress on Controversies in Cryopreservation of Stem Cells, Reproductive Cells, Tissue & Organs (CRYO)

Valencia • Spain • April 22-25, 2010

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VENUEConvention & Exhibition Centre Feria ValenciaAvda. De Las Ferias s/nValencia, 46035SpainTel: +34 96 386-1517www.centroeventos.feriavalencia.com

LANGUAGEThe official language of the Congress is English.

CONGRESS SECRETARIAT AND SPONSORSHIP/ EXHIBITION CONTACTComtecMed53, Rothschild Boulevard, PO Box 68Tel Aviv, 61000, IsraelTel: +972 3 5666166Fax: +972 3 5666177E-mail: [email protected]: www.comtecmed.com/cryo

LIABILITY AND INSURANCEThe organizer carries no liability whatsoever for injuries or damages involving persons and/or property during theCongress. Participants are advised to issue their own personal travel and health insurance for their trip.

� 17 �

GENERAL INFORMATION

The 1st World Congress on Controversies in Cryopreservation of Stem Cells, Reproductive Cells, Tissue & Organs (CRYO)

Valencia • Spain • April 22-25, 2010

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� 18 �

EXHIBITIONA professional exhibition will be held at the Hilton Valencia, in conjunction with the Congress. The floor plan hasbeen designed so as to maximize the exhibitors’ exposure to the delegates. Coffee breaks will be held in thisexhibition area.

EXHIBITION SPACESponsors: Euro 400 per additional sq.mNon Sponsors: Euro 600 per sq.mThe minimum booth size is 5x3 sq.m

Additional information about the exhibition will be available on the official website of the Congress.

The 1st World Congress on Controversies in Cryopreservation of Stem Cells, Reproductive Cells, Tissue & Organs (CRYO)

Valencia • Spain • April 22-25, 2010

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Company Name:

Contact Name:

Address:

Post/Zip Code: Country:

Telephone: Fax:

Email: Website:

Signature: Date:

I would like to book the following sponsorship items:

Sponsors: Euro 400 per additional sq.m

Non Sponsors: Euro 600 per sq.m (minimum booth size: 5x3 meter)

I would like to book exhibition space:

ComtecMed – Medical Congresses53 Rothschild BoulevardP.O. Box 58Tel Aviv 61000, Israel

Fax: +972 3 5666177Tel: +972 3 5666166Email: [email protected]: www.comtecmed.com/cryo/2010

Please call me to discuss the sponsorship package

SPONSORSHIP BOOKING FORM

VALENCIA • SPAIN • APRIL 22-25, 2010

The 1st World Congress on Controversies in Cryopreservation of Stem Cells,Reproductive Cells, Tissue & Organs (CRYO)

SPONSORSHIP ITEM PRICE �

Continuing medical education (CME) Approved Symposium 30,000 Euro

Satellite Symposium (Non-CME approved) 40,000 Euro

Pre/Post- Congress Satellite Symposium (Non-CME approved) 50,000 Euro

Lunch 25,000 Euro

Welcome Reception 15,000 Euro

Congress Program 15,000 Euro

E-Posters 10,000 Euro

Faculty Dinner 10,000 Euro

Internet Center 10,000 Euro

Participants’ Bags 10,000 Euro

CD-ROM 10,000 Euro

Congress Website 8,000 Euro

Video Webcast 5,000 Euro

Audio Webcast 2,500 Euro

Mini/Pocket Program 5,000 Euro

Translation 5,000 Euro

Writing Pads and Pens 5,000 Euro

Lanyards (sponsor provides) 3,000 Euro

Lanyards (congress provides) 6,000 Euro

European Speaker 3,000 Euro

Non-European Speaker 6,000 Euro

Prizes for Outstanding Abstracts 3,000 Euro

Brochure Insert 3,000 Euro

Coffee Break 2,000 Euro

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The 1st World Congress on Controversies inCryopreservation of Stem Cells,

Reproductive Cells, Tissue & Organs (CRYO)

Headquarters and Administration:53 Rothschild Boulevard,PO Box 68,Tel Aviv 61000, IsraelTel: +972-3-5666166Fax: +972-3-5666177Email: [email protected]

Comtec Spain:Bailén, 95-97,pral. 1. a - 08009Barcelona, SpainTel: +34-93-2081145Fax: +34-93-4579291Email: [email protected]

Comtec China:175 Xiang Yang Road South,Shanghai 200031ChinaTel: +86-21-54660460Fax: +86-21-54660450Email: [email protected]

www.comtecmed.com/cryo