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    TEXTBOOK DISCUSSION

    A. Definition

    Cerebrovascular diseases

    Cerebrovascular disease encompasses a number of disorders involving vessels in the cerebral

    circulation. These disorders include stroke and transient ischemic attacks (TIAs), aneurysmal

    subarachnoid hemorrhage, and arteriovenous malformations.

    Stroke is the syndrome of acute focal neurologic deficit from a vascular disorder that injures

    brain tissue. The term brain attack has been promoted to highlight that time-dependent tissue

    damage occurs and to raise awareness of the need for rapid emergency treatment, similar to

    that with heart attack.

    There are two main types of strokes: ischemic and hemorrhagic.

    Ischemic Stroke

    Ischemic strokes are caused by cerebrovascular obstruction by thrombosis or emboli. A

    common classification system identifies five stroke subtypes: ischemic penumbra in evolving

    stroke, transient ischemic attack, large vessel stroke, small vessel stroke, and cardiogenic

    embolic stroke.

    Hemorrhagic Stroke

    The most frequently fatal stroke is a spontaneous hemorrhage into the brain substance. Withrupture of a blood vessel, hemorrhage into the brain tissue occurs, resulting in edema,

    compression of the brain contents, or spasm of the adjacent blood vessels. In the most

    common situation, hemorrhage into the basal ganglia results in contralateral hemiplegia, with

    initial flaccidity progressing to spasticity. The hemorrhage and resultant edema exert great

    pressure on the brain substance, and the clinical course progresses rapidly to coma and

    frequently to death.

    B. Signs and symptoms

    According to textbook As manifested by patient

    Weakness of face -

    Weakness of the arm + August 2, 2013

    Unilateral numbness -

    Vision loss in one eye -

    Language disturbance + August 2, 2013

    Aphasia + August 2, 2013

    Sudden, unexplained imbalance or ataxia + August 2, 2013

    A. Definition

    Unstable Angina (NonST-Segment Elevation Myocardial Infarction)

    Unstable angina is considered to be a clinical syndrome of myocardial ischemia ranging

    between stable angina and myocardial infarction. It most frequently results from

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    atherosclerotic plaque disruption, platelet aggregation, and secondary hemostasis.In contrast

    to stable angina, the pain associated with unstable angina has a more persistent and severe

    course and is characterized by at least one of three features: (1) it occurs at rest usually lasting

    more than 20 minutes; (2) it is severe and described as frank pain and of new onset; and (3) it

    occurs with a pattern that is more severe, prolonged, or frequent than previously experienced.Persons who have no evidence of serum markers for myocardial damage are considered to

    have unstable angina, whereas a diagnosis of nonST-segment elevation myocardial infarction

    is indicated if a serum marker of myocardial injury is present.

    B. Signs and symptoms

    According to textbook As manifested by patient

    Chest pain or discomfort + August 2, 2013

    Pain in arms, neck, jaw, shoulder or back

    accompanying chest pain

    -

    Nausea + August 2, 2013

    Fatigue -

    Shortness of breath -

    Excessive sweating -

    Dizziness -

    A. Definition

    Hypertensive Cardiovascular Disease

    Uncontrolled and prolonged elevation of BP can lead to a variety of changes in the myocardial

    structure, coronary vasculature, and conduction system of the heart. These changes in turn can

    lead to the development of left ventricular hypertrophy (LVH), coronary artery disease (CAD),

    various conduction system diseases, and systolic and diastolic dysfunction of the myocardium,

    complications that manifest clinically as angina or myocardial infarction, cardiac arrhythmias

    (especially atrial fibrillation), and congestive heart failure (CHF).

    Thus, hypertensive heart disease is a term applied generally to heart diseases, such as LVH,coronary artery disease, cardiac arrhythmias, and CHF, that are caused by the direct or indirect

    effects of elevated BP. Although these diseases generally develop in response to chronically

    elevated BP, marked and acute elevation of BP can lead to accentuation of an underlying

    predisposition to any of the symptoms traditionally associated with chronic hypertension.

    B. Signs and Symptoms

    According to textbook As manifested by patient

    High blood pressure + August 2010

    Enlarged heart and irregular heartbeat -

    Fluid in the lungs or lower extremities + August 10, 2013

    Unusual heart sounds -

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    A. Definition

    Type 2 Diabetes

    The two main problems related to insulin in type 2 diabetes are insulin resistance and impaired

    insulin secretion. Insulin resistance refers to a decreased tissue sensitivity to insulin. Normally,insulin binds to special receptors on cell surfaces and initiates a series of reactions involved in

    glucose metabolism. In type 2 diabetes, these intracellular reactions are diminished, thus

    rendering insulin less effective at stimulating glucose uptake by the tissues and at regulating

    glucose release by the liver. The exact mechanisms that lead to insulin resistance and impaired

    insulin secretion in type 2 diabetes are unknown, although genetic factors are thought to play a

    role.

    To overcome insulin resistance and to prevent the buildup of glucose in the blood, increased

    amounts of insulin must be secreted to maintain the glucose level at a normal or slightly

    elevated level.

    B. Signs and symptoms

    According to textbook As manifested by patient

    Fatigue -

    Irritability + August 10, 2013

    Polyuria -

    Polydipsia -

    Slow healing of skin wounds -

    Vaginal infections -Blurred vision + August 10, 2013

    Increased hunger -

    Weight loss -

    Areas of darkened skin + August 10, 2013

    SCHEMATIC DIAGRAM

    Predisposing Factors Precipitating Factors

    Obesity Increased carbohydrate and fat intake

    Race/Ethnicity Lack of exercise

    History of GDM History of smoking

    Delivery of babies over 9Ilbs History of alcoholism

    Family history

    Gender: Female

    Age>45: 64 years old