Tb
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Transcript of Tb
Introduction:Tuberculosis is caused by Mycobacterium tuberculosis.It is an air borne disease and is spread
through droplet nuclei.It mostly effects the lungs.
History:
Tubercular decay has been found in the spines of Egyptian mummies.
Dr. Robert Koch discovered the tuberculosis bacillus
Staining:High lipid and mycolic acid content makes
staining difficult.Special staining techniques: Acid fast staining Auramine-Rodamine staining Fluorescent microscopy
Symptoms
•Chest pain•Coughing blood•Chills•Appetite loss•Weight loss
Risk factors for TB HIV infection
Low socioeconomic status
Alcoholism
Homelessness
Diseases that weaken the immune system
Migration from a country with a high number of cases
Crowded living conditions
Screening:
Tuberculin test or Mantoux test. It produces false negative tests.
Interferon-γ release assays.Chest Photofluorography. The latter two techniques are expensive but
results are more reliable.
Drug resistant Tb:Multi drug resistant Tb and Extensively drug
resistant Tb are major health issues.These have resistance to the primary line of
drugs given to the patientThis has made the cure of Tb difficult.
Treatment:Antibiotics like isoniazid and rifampicin
are commonly used.DOTS
Role of Diet:Malnutrition aggravates the severity of
infectionChemotherapy effects nutritional statusBalanced diet is required to build immunity
and to fight against the disease.Should increase intake of nutrients like
proteins, minerals and vitamins.Along with drugs Balanced diet is required to
fight the disease.
Dietary management: An all-fruit diet for three days. Take three
meals a day of fresh juicy fruits at five-hourly intervals.
A fruit and milk diet for further 10 days, adding a cup of milk to each fruit meal.
After this a balanced vegetarian diet should be given
PRINCIPLE OF THE DIET is HIGH CARBOHYDRATE, HIGH PROTEIN, LOW FAT, HIGH CALCIUM which is non-oily and non-spicy.
AVOID Tea, coffee, sugar, white flour and products made from them, refined foods, fried foods, flesh foods, alcohol and smoking.
Dietary recommendations: Dietary FatEat less than ten percent of calories from
saturated fats and less than 300 mg/day of cholesterol, and eat as few trans-fats (hydrogenated fat) as possible.
Maintain total intake of fats/oils at between 20-35 percent of calories, with most fat coming from polyunsaturated and monounsaturated fat, such as oily fish, nuts, and vegetable oils.
Regarding meat, poultry, dry beans, and milk or milk products, choose lean, low-fat, or fat-free options.
Carbohydrates:Eat fibre-rich fruits, vegetables, and whole
grains as often as possible.Consume foods and drinks with little added
sugars or caloric sweeteners.
Protein:Eat lean meats and poultry.Eat a variety of protein rich foods, with more
fish, beans, peas, nuts and seeds.Bake, broil, or grill food.
Vitamins:Vitamin A, C, D should be consumed more.
Minerals:
Calcium:It is required for calcification of lesions.
Iron:Deficiency leads to anemia which
aggravates the condition.
Sodium and Potassium:Eat less than 2,300 mg (approximately 1
teaspoon of salt) of sodium per day.Choose low-sodium foods, and do not add salt
when cooking. Also, eat potassium-rich foods, such as fruits and vegetables.
Prevention of Tuberculosis:BCG vaccine is major part of Tb control
programme.Its efficacy is only 80% RNTCP- Revised National Tb Control
ProgrammeRecombinant tuberculosis vaccine is under
trials